Yan Xu

发表

Virtual Screening, Biological Evaluation, and 3D-QSAR Studies of New HIV-1 Entry Inhibitors That Function via the CD4 Primary Receptor

Siyu Zhu, R. Schooley, J. An, 2018, Molecules.

Structural and Biological Characterizations of Novel High-Affinity Fluorescent Probes with Overlapped and Distinctive Binding Regions on CXCR4

R. Schooley, J. An, Ziwei Huang, 2019, Molecules.

Synergistic inhibition of hepatitis C virus infection by a novel microtubule inhibitor in combination with daclatasvir

R. Schooley, Mohsin Khan, J. An, 2022, Biochemistry and biophysics reports.

Targeting chemokine receptor CXCR4 for treatment of HIV-1 infection, tumor progression, and metastasis.

Won-Tak Choi, J. An, Yan Xu, 2014, Current topics in medicinal chemistry.

Discovery and Computational Analyses of Novel Small Molecule Zika Virus Inhibitors

R. Schooley, J. An, Ziwei Huang, 2019, Molecules.

Pharmacokinetics of a novel microtubule inhibitor mHA11 in rats.

Yinsong Zhu, J. An, Ziwei Huang, 2019, Chemico-biological interactions.

A novel small molecule CXCR4 antagonist potently mobilizes hematopoietic stem cells in mice and monkeys

A. Ciechanover, J. An, Ziwei Huang, 2020, Stem cell research & therapy.

Design, synthesis, and biological characterization of a new class of symmetrical polyamine-based small molecule CXCR4 antagonists.

R. Schooley, J. An, Ziwei Huang, 2020, European journal of medicinal chemistry.

A synthetic bivalent ligand of CXCR4 inhibits HIV infection.

D. Richman, J. An, Ziwei Huang, 2013, Biochemical and biophysical research communications.

Critical role in CXCR4 signaling and internalization of the polypeptide main chain in the amino terminus of SDF-1α probed by novel N-methylated synthetically and modularly modified chemokine analogues.

Won-Tak Choi, C. Dong, J. An, 2012, Biochemistry.

Novel Bivalent and D-Peptide Ligands of CXCR4 Mobilize Hematopoietic Progenitor Cells to the Blood in C3H/HeJ Mice

E. Snyder, J. An, Ziwei Huang, 2018, Cell transplantation.

Discovery and Characterization of a Novel Cyclic Peptide That Effectively Inhibits Ephrin Binding to the EphA4 Receptor and Displays Anti-Angiogenesis Activity

J. An, Ziwei Huang, Xiaofeng Han, 2013, PloS one.

Development of a Novel Fluorescence Polarization–Based Assay for Studying the β-Catenin/Tcf4 Interaction

Xiaobin Han, J. An, Ziwei Huang, 2012, Journal of biomolecular screening.

IV-1 gp120-CXCR4 recognition probed with synthetic nanomolar affinity D-peptides containing fragments of gp120 V3 loop.

R. Schooley, J. An, Ziwei Huang, 2022, European journal of medicinal chemistry.

LC–MS/MS assay for the determination of a novel D‐peptide antagonist of CXCR4 in rat plasma and its application to a preclinical pharmacokinetic study

Yinsong Zhu, J. An, Ziwei Huang, 2018, Journal of pharmaceutical and biomedical analysis.

Design and Synthesis of Potent Bivalent Peptide Agonists Targeting the EphA2 Receptor.

E. Pasquale, J. An, Ziwei Huang, 2013, ACS medicinal chemistry letters.

A synthetic bivalent peptide ligand of EphB4 with potent agonistic activity.

A. Ciechanover, J. An, Ziwei Huang, 2022, European journal of medicinal chemistry.

Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities.

J. An, Ziwei Huang, Huijun Zhang, 2018, European journal of medicinal chemistry.

The chemical biology of apoptosis: Revisited after 17 years.

J. An, Ziwei Huang, Shu Yang, 2019, European journal of medicinal chemistry.

Structure-based discovery of a novel inhibitor targeting the β-catenin/Tcf4 interaction.

N. Lin, Xiaobin Han, J. An, 2012, Biochemistry.

Chemical mutagenesis of a GPCR ligand: Detoxifying “inflammo-attraction” to direct therapeutic stem cell migration

R. Sidman, Yinsong Zhu, E. Snyder, 2020, Proceedings of the National Academy of Sciences.

A fragment integrational approach to GPCR inhibition: Identification of a high affinity small molecule CXCR4 antagonist.

A. Ciechanover, R. Schooley, J. An, 2022, European journal of medicinal chemistry.

Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4).

Won-Tak Choi, Won-Tak Choi, J. An, 2012, Journal of medicinal chemistry.

A new class of α-ketoamide derivatives with potent anticancer and anti-SARS-CoV-2 activities

A. Ciechanover, A. Warshel, K. Yuen, 2021, European Journal of Medicinal Chemistry.

High affinity CXCR4 inhibitors generated by linking low affinity peptides.

R. Schooley, J. An, Ziwei Huang, 2019, European journal of medicinal chemistry.

Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4).

Won-Tak Choi, J. An, Ziwei Huang, 2011, Journal of medicinal chemistry.

Design, synthesis and characterization of novel small molecular inhibitors of ephrin-B2 binding to EphB4.

N. Lin, R. Noberini, E. Pasquale, 2013, Biochemical pharmacology.

Structural and Biological Characterizations of Novel High-Affinity Fluorescent Probes with Overlapped and Distinctive Binding Regions on CXCR4

R. Schooley, J. An, Ziwei Huang, 2019, Molecules.

CXCR4 Recognition by L- and D-Peptides Containing the Full-Length V3 Loop of HIV-1 gp120

J. An, Ziwei Huang, Lina S. Huang, 2023, Viruses.

A Chemical Strategy for the Degradation of the Main Protease of SARS-CoV-2 in Cells.

A. Warshel, Yan Xu, Xiaohong Sang, 2023, Journal of the American Chemical Society.