Kristen L. Karlin

发表

The spliceosome is a therapeutic vulnerability in MYC-driven cancer

Sarah J. Kurley, Lukas M. Simon, Ido Golding, 2015, Nature.

Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression

Henry W. Long, C. T. Mowery, Charles Y. Lin, 2018, Cell reports.

ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.

D. Parsons, S. Pfister, Baoli Hu, 2021, Cancer discovery.

Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer

Jitendra Kumar Meena, Charles Y. Lin, F. Stossi, 2021, Cell.

Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma

Donald R. Polaski, J. Bradner, T. Westbrook, 2018, Nature Genetics.

The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor.

C. Shaw, D. Edwards, S. Hilsenbeck, 2014, Cell reports.

Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase

Adrian V. Lee, Laura M. Heiser, P. Spellman, 2014, Breast Cancer Research.

Tcf3 promotes cell migration and wound repair through regulation of lipocalin 2

T. Westbrook, V. Poli, T. Shaver, 2014, Nature Communications.

Corrigendum: Mutations in the transcriptional repressor REST predispose to Wilms tumor

C. Shaw, S. Seal, N. Rahman, 2016, Nature Genetics.

Mutations in the transcriptional repressor REST predispose to Wilms tumor

C. Shaw, S. Seal, N. Rahman, 2015, Nature Genetics.

Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma

Donald R. Polaski, Charles Y. Lin, J. Bradner, 2018, Nature Genetics.

Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors.

Charles Y. Lin, S. Knapp, T. Westbrook, 2020, Cell chemical biology.