A. Guo

发表

CYP4A/20-HETE regulates ischemia-induced neovascularization via its actions on endothelial progenitor and preexisting endothelial cells.

J. Falck, A. Arbab, M. Schwartzman, 2019, American journal of physiology. Heart and circulatory physiology.

20-HETE can act as a nonhypoxic regulator of HIF-1alpha in human microvascular endothelial cells.

P. Edwards, A. Guo, A. G. Scicli, 2009, American journal of physiology. Heart and circulatory physiology.

20-HETE in neovascularization.

Li Chen, A. Guo, R. Ackerman, 2012, Prostaglandins & other lipid mediators.

Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.

S. Dulchavsky, D. Deeb, Xiaohua Gao, 2011, Anticancer research.

Neutrophil-Derived Myeloperoxidase and Hypochlorous Acid Critically Contribute to 20-Hydroxyeicosatetraenoic Acid Increases that Drive Postischemic Angiogenesis

J. Falck, M. Schwartzman, T. Jeitner, 2022, The Journal of Pharmacology and Experimental Therapeutics.

20-HETE contributes to ischemia-induced angiogenesis.

J. Falck, M. Schwartzman, K. Gotlinger, 2016, Vascular pharmacology.

Elevated level of pro-inflammatory eicosanoids and EPC dysfunction in diabetic patients with cardiac ischemia.

R. Kornowski, N. Abraham, K. Gotlinger, 2013, Prostaglandins & other lipid mediators.

Expression of CYP4A1 in U251 Human Glioma Cell Induces Hyperproliferative Phenotype in Vitro and Rapidly Growing Tumors in Vivo

N. Lehman, J. Falck, R. Roman, 2008, Journal of Pharmacology and Experimental Therapeutics.

Role of 12-lipoxygenase in regulation of ovarian cancer cell proliferation and survival

Xiuli Liu, A. Munkarah, R. Ali-Fehmi, 2011, Cancer Chemotherapy and Pharmacology.

HET0016, a Selective Inhibitor of 20-HETE Synthesis, Decreases Pro-Angiogenic Factors and Inhibits Growth of Triple Negative Breast Cancer in Mice

A. Arbab, N. Varma, A. Iskander, 2014, PloS one.

20-HETE synthesis inhibition promotes cerebral protection after intracerebral hemorrhage without inhibiting angiogenesis

R. Koehler, Xiaoning Han, J. Falck, 2019, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

20-HETE Regulates the Angiogenic Functions of Human Endothelial Progenitor Cells and Contributes to Angiogenesis In Vivo

J. Falck, A. Arbab, M. Schwartzman, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Cardiovascular Inflammation

A. Guo, J. Stubbe, Miao Wang, 2013, Mediators of inflammation.

novel localization in vascular endothelium CYP4A mRNA, protein, and product in rat lungs:

E. Jacobs, J. Falck, R. Roman, 2015 .

The Cytochrome P450 4A/F-20-Hydroxyeicosatetraenoic Acid System: A Regulator of Endothelial Precursor Cells Derived from Human Umbilical Cord Blood

J. Falck, R. Roman, A. Arbab, 2011, Journal of Pharmacology and Experimental Therapeutics.

The Cytochrome P 450 4 A / F-20-Hydroxyeicosatetraenoic Acid System : A Regulator of Endothelial Precursor Cells Derived from Human Umbilical Cord Blood

J. Falck, R. Roman, A. Arbab, 2011 .

Activation of Vascular Endothelial Growth Factor through Reactive Oxygen Species Mediates 20-Hydroxyeicosatetraenoic Acid-Induced Endothelial Cell Proliferation

J. Falck, R. Roman, A. Arbab, 2007, Journal of Pharmacology and Experimental Therapeutics.

Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6.

Y. Li, A. Guo, T. Tang, 2014, Toxicology and applied pharmacology.

Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer.

Y. Li, J. Falck, Wei Yu, 2013, Toxicology and applied pharmacology.

CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis

Jing Zhang, X. Chen, J. Yang, 2017, Oncogene.

Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis.

G. Trick, P. Edwards, A. Guo, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

Intravenous Formulation of HET0016 Decreased Human Glioblastoma Growth and Implicated Survival Benefit in Rat Xenograft Models

A. Arbab, B. R. Achyut, A. Iskander, 2017, Scientific Reports.

Human Cord Blood-Derived AC133+ Progenitor Cells Preserve Endothelial Progenitor Characteristics after Long Term In Vitro Expansion

A. Arbab, B. Janic, N. Varma, 2010, PloS one.

Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid

Xia Li, R. Tiwari, Xiufeng Yu, 2023, Frontiers in Pharmacology.

Cytochrome P450 ω-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer

J. Falck, Li Chen, A. Guo, 2011, Cancer Chemotherapy and Pharmacology.

Editorial Cardiovascular Inflammation

MiaoWang, A. Guo, J. Stubbe, 2015 .

Combination of vatalanib and a 20-HETE synthesis inhibitor results in decreased tumor growth in an animal model of human glioma

T. Mikkelsen, J. Ewing, A. Arbab, 2016, OncoTargets and therapy.

Eicosanoids: Emerging contributors in stem cell-mediated wound healing.

Yanzhou Liu, A. Guo, Li Chen, 2017, Prostaglandins & other lipid mediators.

Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion.

Y. Li, Jing Zhang, J. Yue, 2014, Toxicology and applied pharmacology.