Wenqin Ying

CRISPR/Cas9-mediated targeted chromosome elimination

Hui Yang, Yu Wei, Jie Ping, 2017, Genome Biology.

A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects

Hui Yang, Changyang Zhou, Yixue Li, 2020, Nature Methods.

CRISPR/Cas9 – Mediated Precise Targeted Integration In Vivo Using a Double Cut Donor with Short Homology Arms

Xin Wang, Hui Yang, Pengyu Huang, 2017, EBioMedicine.

One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs

Hui Yang, Yu Wei, Changyang Zhou, 2017, Cell Research.

Base-Editing-Mediated R17H Substitution in Histone H3 Reveals Methylation-Dependent Regulation of Yap Signaling and Early Mouse Embryo Development.

Shisheng Huang, Yu Wei, Hui Yang, 2019, Cell reports.

Base editing generates substantial off-target single nucleotide variants

Lars M. Steinmetz, Hui Yang, L. Steinmetz, 2018, bioRxiv.