Clarissa G Jakob

SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding.

Hongyu Zhao, Ying Wang, Zhiqin Ji, 2017, Bioorganic & medicinal chemistry letters.

The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex.

Jun Guo, Kenneth M Comess, Haizhong Zhu, 2017, Nature chemical biology.

Crystal structures of DPP-IV (CD26) from rat kidney exhibit flexible accommodation of peptidase-selective inhibitors.

Vincent S Stoll, K. Longenecker, V. Stoll, 2006, Biochemistry.

Discovery of potent inhibitors of dihydroneopterin aldolase using CrystaLEAD high-throughput X-ray crystallographic screening and structure-directed lead optimization.

Jean M. Severin, Rolf Wagner, Vincent S Stoll, 2004, Journal of medicinal chemistry.