C. Loscher

发表

Adaptive Evolution as a Predictor of Species-Specific Innate Immune Response

S. Edwards, M. O’Connell, Claire C. Morgan, 2015, Molecular biology and evolution.

IL-1β-dependent neurological effects of the whole cell pertussis vaccine: a role for IL-1-associated signalling components in vaccine reactogenicity

M. Lynch, K. Mills, C. Loscher, 2003, Journal of Neuroimmunology.

Conjugated linoleic acid suppresses dendritic cell activation and subsequent Th17 responses.

H. Roche, K. Mills, C. Reynolds, 2014, The Journal of nutritional biochemistry.

Glycerol-induced seizure: involvement of IL-1beta and glutamate.

M. Lynch, K. Mills, S. Donnelly, 1999, Neuroreport.

Antidiabetic Effects of cis-9, trans-11–Conjugated Linoleic Acid May Be Mediated via Anti-Inflammatory Effects in White Adipose Tissue

E. Noone, H. Roche, A. Nugent, 2007, Diabetes.

InductionCells through ERK-Mediated IL-10 Activation and IL-12 Production in Dendritic B k Conjugated Linoleic Acid Suppresses NF-Kelleher,

H. Roche, O. Leavy, K. Mills, 2005 .

Conjugated Linoleic Acid Suppresses NF- B Activation and IL-12 Production in Dendritic Cells through ERK-Mediated IL-10 Induction

H. Roche, O. Leavy, K. Mills, 2005 .

Conjugated Linoleic Acid Suppresses NF-κB Activation and IL-12 Production in Dendritic Cells through ERK-Mediated IL-10 Induction1

H. Roche, O. Leavy, K. Mills, 2005, The Journal of Immunology.

The Limonoids TS3 and Rubescin E Induce Apoptosis in Human Hepatoma Cell Lines and Interfere with NF-κB Signaling

G. Tiegs, N. Lange, C. Loscher, 2016, PloS one.

Embryonic rat vascular smooth muscle cells revisited - a model for neonatal, neointimal SMC or differentiated vascular stem cells?

P. Cahill, Roya Hakimjavadi, C. Loscher, 2014, Vascular cell.

Adult vascular smooth muscle cells in culture express neural stem cell markers typical of resident multipotent vascular stem cells

P. Cahill, Roya Hakimjavadi, C. Loscher, 2014, Cell and Tissue Research.

Anti-inflammatory effects of EPA and DHA are dependent upon time and dose-response elements associated with LPS stimulation in THP-1-derived macrophages.

H. Roche, C. Loscher, A. Mullen, 2010, The Journal of nutritional biochemistry.

Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A4 mimetics (sLXms).

E. Brennan, M. Perretti, P. Fallon, 2019, European journal of medicinal chemistry.

Synthesis and Biological Evaluation of Pyridine‐Containing Lipoxin A4 Analogues

C. Godson, P. Guiry, C. Loscher, 2010, ChemMedChem.

Syntaxin-4 is essential for IgE secretion by plasma cells.

D. Walls, Arman Rahman, C. Loscher, 2013, Biochemical and biophysical research communications.

Modulation of gene expression in U251 glioblastoma cells by binding of mutant p53 R273H to intronic and intergenic sequences

W. Deppert, V. Tichý, M. Brázdová, 2009, Nucleic acids research.

Asymmetric Synthesis and Biological Evaluation of 1,3- and 1,4-Disubstituted Benzo-Type Lipoxin A4 Analogues.

P. Guiry, C. Loscher, C. McCarthy, 2014 .

Profiling Humoral Immune Responses to Clostridium difficile-Specific Antigens by Protein Microarray Analysis

P. Tighe, O. Negm, M. Hamed, 2015, Clinical and Vaccine Immunology.

IL‐1F5 mediates anti‐inflammatory activity in the brain through induction of IL‐4 following interaction with SIGIRR/TIR8

M. Lynch, C. Garlanda, A. Mantovani, 2008, Journal of neurochemistry.

A Role for Syntaxin 3 in the Secretion of IL-6 from Dendritic Cells Following Activation of Toll-Like Receptors

C. Loscher, K. Rochfort, J. Decourcey, 2015, Front. Immunol..

Interleukin-1β-dependent changes in the hippocampus following parenteral immunization with a whole cell pertussis vaccine

M. Lynch, K. Mills, S. Donnelly, 2000, Journal of Neuroimmunology.

Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response

D. Kelleher, M. O’Connell, T. Rogers, 2017, BMC Evolutionary Biology.

Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid.

H. Roche, C. Loscher, A. Mullen, 2007, The Journal of nutritional biochemistry.

Activation of liver X receptor suppresses the production of the IL-12 family of cytokines by blocking nuclear translocation of NF-κBp50

S. Melgar, H. Kagechika, John Macsharry, 2014, Innate immunity.

Autoantibodies - enemies, and/or potential allies?

Hui Ma, C. Loscher, C. Murphy, 2022, Frontiers in Immunology.

Cis-9, trans-11-conjugated linoleic acid but not its precursor trans-vaccenic acid attenuate inflammatory markers in the human colonic epithelial cell line Caco-2

H. Roche, A. Moloney, C. Reynolds, 2008, British Journal of Nutrition.

Conjugated linoleic acid suppresses IRF3 activation via modulation of CD14.

L. O’Neill, C. McCoy, Sarah L. Doyle, 2013, The Journal of nutritional biochemistry.

Aflatoxins B(1), B(2) and G(1) modulate cytokine secretion and cell surface marker expression in J774A.1 murine macrophages.

C. Loscher, Edwina Stack, J. Bruneau, 2012, Toxicology in vitro : an international journal published in association with BIBRA.

Whole-Cell but Not Acellular Pertussis Vaccines Induce Convulsive Activity in Mice: Evidence of a Role for Toxin-Induced Interleukin-1β in a New Murine Model for Analysis of Neuronal Side Effects of Vaccination

K. Mills, S. Donnelly, C. Loscher, 2001, Infection and Immunity.

A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4.

H. Roche, A. Moloney, K. Mills, 2009, The Journal of nutrition.

A Conjugated Linoleic Acid-Enriched Beef Diet Attenuates Lipopolysaccharide-Induced Inflammation in Mice in Part through PPAR g-Mediated Suppression of Toll-Like Receptor 41 – 3

H. Roche, A. Moloney, K. Mills, 2009 .

Interleukin-1 receptor antagonist exerts agonist activity in the hippocampus independent of the interleukin-1 type I receptor

M. Lynch, K. Mills, C. Loscher, 2003, Journal of Neuroimmunology.

Proinflammatory responses in the murine brain after intranasal delivery of cholera toxin: implications for the use of AB toxins as adjuvants in intranasal vaccines.

M. Lynch, K. Mills, E. Lavelle, 2005, The Journal of infectious diseases.

Induction of inflammatory cytokines in the brain following respiratory infection with Bordetella pertussis

M. Lynch, K. Mills, S. Donnelly, 2000, Journal of Neuroimmunology.

Exopolysaccharides of Lactic Acid Bacteria: Production, Purification and Health Benefits towards Functional Food

D. Brabazon, C. Loscher, K. Rochfort, 2022, Nutrients.

Colon cancer associated genes exhibit signatures of positive selection at functionally significant positions

H. Ruskin, M. O’Connell, Claire C. Morgan, 2012, BMC Evolutionary Biology.

Khaya grandifoliola C.DC: a potential source of active ingredients against hepatitis C virus in vitro

G. Tiegs, Y. Rouillé, K. Séron, 2016, Archives of Virology.

Mechanisms of osteopontin-mediated effects on chronic hepatic inflammation and cancer

V. Lohmann, G. Tiegs, C. Loscher, 2015 .

Khaya grandifoliola C.DC: a potential source of active ingredients against hepatitis C virus in vitro

G. Tiegs, Y. Rouillé, K. Séron, 2016, Archives of Virology.

Inhibition of duck hepatitis B virus infection of liver cells by combined treatment with viral e antigen and carbohydrates.

M. Bruns, C. Loscher, Alicja Iwanski, 2008, The Journal of general virology.

Modulation of the Nuclear Transcription Factor 1 of Activated T Cells by Duck Hepatitis B Virus 2 3 By 4 5

M. Bruns, C. Loscher, U. Matschl, 2009 .

An Emerging Role for SNARE Proteins in Dendritic Cell Function

C. Loscher, K. Rochfort, J. Decourcey, 2015, Front. Immunol..

Three-dimensional organotypic co-culture model of intestinal epithelial cells and macrophages to study Salmonella enterica colonization patterns

S. Clemett, K. Roland, Jennifer Barrila, 2017, npj Microgravity.

The Fasciola hepatica Tegumental Antigen Suppresses Dendritic Cell Maturation and Function

P. Brophy, S. O'Neill, David J. Dowling, 2009, Infection and Immunity.

Colon cancer associated genes exhibit signatures of positive selection at functionally significant positions

Mark Lynch, Heather J Ruskin, H. Ruskin, 2012, BMC Evolutionary Biology.

Patulin, Deoxynivalenol, Zearalenone and T-2 Toxin Affect Viability and Modulate Cytokine Secretion in J774A.1 Murine Macrophages

G. Kijanka, C. Loscher, Jonathan H. Loftus, 2016 .

A Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins

A. Ryan, P. Fallon, D. Kelleher, 2011, PLoS pathogens.

Omega-3 fatty acids attenuate dendritic cell function via NF-κB independent of PPARγ.

H. Roche, K. Mills, C. Reynolds, 2011, The Journal of nutritional biochemistry.

Surface layer proteins isolated from Clostridium difficile induce clearance responses in macrophages.

D. Kelleher, M. O’Connell, C. Loscher, 2014, Microbes and infection.

Activation of p38 Plays a Pivotal Role in the Inhibitory Effect of Lipopolysaccharide and Interleukin-1β on Long Term Potentiation in Rat Dentate Gyrus*

M. Lynch, K. Mills, Y. Nolan, 2003, Journal of Biological Chemistry.

The emerging roles of intestinal macrophages in sickness and in health

C. Loscher, M. Kristek, 2014 .

Adaptive Evolution in TRIF Leads to Discordance between Human and Mouse Innate Immune Signaling

Edel M Hyland, M. O’Connell, A. Webb, 2021, Genome biology and evolution.

Obese IL-1 receptor-I-deficient (IL-1RI−/−) mice are protected against diet-induced insulin resistance via a down-regulation of inflammation and oxidative stress in adipose tissue: a proteomics investigation

H. Roche, G. Horgan, J. Browne, 2008, Proceedings of the Nutrition Society.

Network analysis of adipose tissue gene expression highlights altered metabolic and regulatory transcriptomic activity in high-fat-diet-fed IL-1RI knockout mice.

Melissa J. Morine, John A Browne, H. Roche, 2013, The Journal of nutritional biochemistry.

Schizophrenia interactome with 504 novel protein–protein interactions

Mohamed Thahir, Madhavi K Ganapathiraju, Adam Handen, 2016, npj Schizophrenia.

Divergent mechanisms of cis9, trans11‐ and trans10, cis12‐conjugated linoleic acid affecting insulin resistance and inflammation in apolipoprotein E knockout mice: a proteomics approach

H. Roche, J. Arbonés-Mainar, G. Duncan, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Adult vascular smooth muscle cells in culture express neural stem cell markers typical of resident multipotent vascular stem cells

P. Cahill, Roya Hakimjavadi, C. Loscher, 2014, Cell and Tissue Research.

Glycerol-induced seizure : involvement of IL-1β and glutamate

Sheila Donnelly, Marina A. Lynch, M. Lynch, 1999 .

Matrix Conditions and KLF2-Dependent Induction of Heme Oxygenase-1 Modulate Inhibition of HCV Replication by Fluvastatin

R. Bartenschlager, J. Schrader, A. Lohse, 2014, PloS one.

Degradation of pyroglutamyl-phenylalanyl-proline amide by a pyroglutamyl aminopeptidase purified from membrane fractions of bovine brain.

B. O'connor, C. Loscher, J. A. Kelly, 1997, Biochemical Society transactions.

Targeted Application of Functional Foods as Immune Fitness Boosters in the Defense against Viral Infection

Restituto Tocmo, C. Loscher, D. Finnegan, 2023, Nutrients.

Attenuation of inflammation and cellular stress‐related pathways maintains insulin sensitivity in obese type I interleukin‐1 receptor knockout mice on a high‐fat diet

H. Roche, G. Horgan, K. Mills, 2009, Proteomics.

Soluble factors from colonic epithelial cells contribute to gut homeostasis by modulating macrophage phenotype

C. Loscher, J. Decourcey, L. Collins, 2015, Innate immunity.

Proinflammatory Cytokines in the Adverse Systemic and Neurologic Effects Associated with Parenteral Injection of a Whole Cell Pertussis Vaccine

M. Lynch, K. Mills, C. Loscher, 1998, Annals of the New York Academy of Sciences.

Soluble factors from colonic epithelial cells contribute to gut homeostasis by modulating macrophage phenotype

C. Loscher, J. Decourcey, L. Collins, 2015, Innate Immunity.

The Fasciola hepatica Tegumental Antigen Suppresses Dendritic Cell Maturation and Function

P. Brophy, S. O'Neill, David J. Dowling, 2009, Infection and Immunity.