J. Smeets

发表

Physiologically Based Pharmacokinetic Modeling to Investigate Regional Brain Distribution Kinetics in Rats

Bart Ploeger, Meindert Danhof, B. Ploeger, 2012, The AAPS Journal.

Estrogenic potencies of several environmental pollutants, as determined by vitellogenin induction in a carp hepatocyte assay.

M. van den Berg, J. Giesy, I. van Holsteijn, 1999, Toxicological sciences : an official journal of the Society of Toxicology.

In vitro vitellogenin production by carp (Cyprinus carpio) hepatocytes as a screening method for determining (anti)estrogenic activity of xenobiotics.

M. van den Berg, J. Giesy, N. Kaminski, 1999, Toxicology and applied pharmacology.

Pharmacokinetic–Pharmacodynamic Model for the Reversal of Neuromuscular Blockade by Sugammadex

B. Ploeger, M. Danhof, G. Ruigt, 2009, Anesthesiology.

Cytochrome P4501A induction, benzo[a]pyrene metabolism, and nucleotide adduct formation in fish hepatoma cells: Effect of preexposure to 3,3′,4,4′,5‐pentachlorobiphenyl

M. van den Berg, D. Tillitt, W. Seinen, 1999 .

Cytochrome P4501A induction and testosterone hydroxylation in cultured hepatocytes of four fish species.

M. van den Berg, J. Smeets, J. Everaarts, 2002, Chemosphere.

PD-0034POPULATION PHARMACOKINETICS ANALYSIS OF REGORAFENIB AND ITS ACTIVE METABOLITES FROM THE PHASE III CORRECT STUDY OF METASTATIC COLORECTAL CANCER

M. Ychou, J. Tabernero, A. Grothey, 2013 .

Pharmacokinetic evaluation of three different intramuscular doses of nandrolone decanoate: analysis of serum and urine samples in healthy men.

A. Port, J. Smeets, H. Verheul, 2005, The Journal of clinical endocrinology and metabolism.

Safety, Tolerability and Pharmacokinetics of Sugammadex Using Single High Doses (Up to 96 mg/kg) in Healthy Adult Subjects

J. Smeets, P. Peeters, P. Passier, 2010, Clinical drug investigation.

Safety, tolerability and pharmacokinetics of sugammadex using single high doses (up to 96 mg/kg) in healthy adult subjects: a randomized, double-blind, crossover, placebo-controlled, single-centre study.

M. W. van den Heuvel, J. Smeets, Thijs MP van Iersel, 2010, Clinical drug investigation.

Safety and tolerability of single intravenous doses of sugammadex administered simultaneously with rocuronium or vecuronium in healthy volunteers.

L. Foubert, P. De Kam, J. Smeets, 2008, British journal of anaesthesia.

Sugammadex is cleared rapidly and primarily unchanged via renal excretion

J. Smeets, D. J. van den Dobbelsteen, P. Peeters, 2011, Biopharmaceutics & drug disposition.

Assessment of the Potential for Displacement Interactions with Sugammadex

J. Smeets, Alexandra J. M. Zwiers, S. Rutherford, 2012 .

Assessment of the potential for displacement interactions with sugammadex: a pharmacokinetic-pharmacodynamic modelling approach.

M. W. van den Heuvel, J. Smeets, Alexandra J. M. Zwiers, 2011, Clinical drug investigation.

Sugammadex is not associated with QT/QTc prolongation: methodology aspects of an intravenous moxifloxacin-controlled thorough QT study.

P. De Kam, J. V. van Kuijk, T. Thomsen, 2012, International journal of clinical pharmacology and therapeutics.

In vitro dialysability of sugammadex (Org 25969), a selective relaxant binding agent for reversal of neuromuscular block induced by rocuronium: A-555

J. Smeets, S. Peters, M. D. Zwart, 2006 .

Pharmacokinetics of high doses of the selective relaxant binding agent sugammadex, administered shortly after profound rocuronium-induced neuromuscular block: A-551

J. Egmond, M. Marcus, J. Driessen, 2006 .

The impact of P-glycoprotein functionality on non-steady state relationships between CSF and brain extracellular fluid

M. Danhof, J. Smeets, 2014 .

The impact of P-gp functionality on non-steady state relationships between CSF and brain extracellular fluid

M. Danhof, J. Westerhout, J. Smeets, 2013, Journal of Pharmacokinetics and Pharmacodynamics.

Pharmacokinetics of a granisetron transdermal system for the treatment of chemotherapy-induced nausea and vomiting

H. Drenth, J. Smeets, J. Howell, 2009, Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.

The anti-estrogenicity of Ah receptor agonists in carp (Cyprinus carpio) hepatocytes.

M. van den Berg, J. Giesy, I. van Holsteijn, 1999, Toxicological sciences : an official journal of the Society of Toxicology.

Pharmacokinetics of the selective relaxant binding agent sugammadex, administered for reversal of shallow neuromuscular blockade induced by rocuronium or vecuronium: 9AP2-7

J. Smeets, J. Ingimarsson, C. Rex, 2007 .