S. Dirrig‐Grosch

发表

A transgenic mouse expressing CHMP2Bintron5 mutant in neurons develops histological and behavioural features of amyotrophic lateral sclerosis and frontotemporal dementia.

L. Schaeffer, F. Sellal, J. Loeffler, 2016, Human molecular genetics.

Inhibition by transmembrane peptides of chimeric insulin receptors

D. Aunis, A. Appert-Collin, A. Bennasroune, 2005, Cellular and Molecular Life Sciences CMLS.

Cytoplasmic accumulation of FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and defects in inhibitory synapses

V. Rasche, J. Kassubek, A. Ludolph, 2020, bioRxiv.

Systemic Down-Regulation of Delta-9 Desaturase Promotes Muscle Oxidative Metabolism and Accelerates Muscle Function Recovery following Nerve Injury

J. Loeffler, A. Henriques, E. Marchioni, 2013, PloS one.

Presence of Dynamin—Syntaxin Complexes Associated with Secretory Granules in Adrenal Chromaffin Cells

S. Chasserot-Golaz, M. Bader, M. Galas, 2000, Journal of neurochemistry.

Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis

Ying Sun, A. Ludolph, C. Haass, 2017, Acta Neuropathologica.

Investigating the contribution of VAPB/ALS8 loss of function in amyotrophic lateral sclerosis.

V. Meininger, G. Rouleau, P. Drapeau, 2013, Human molecular genetics.

Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosis

P. Wong, L. H. van den Berg, J. Veldink, 2016, Acta Neuropathologica.

Induction by Cocaine of the Serotonergic 5‐HT3 Receptor in Rat Cerebellum

J. Zwiller, D. Aunis, S. Dirrig‐Grosch, 2006, Annals of the New York Academy of Sciences.

Endogenous Morphine Levels Are Increased in Sepsis: A Partial Implication of Neutrophils

Arnaud H. Muller, F. Delalande, D. Aunis, 2010, PloS one.

Mapping of endogenous morphine‐like compounds in the adult mouse brain: Evidence of their localization in astrocytes and GABAergic cells

Arnaud H. Muller, F. Delalande, D. Aunis, 2011, The Journal of comparative neurology.

Transmembrane peptides as inhibitors of ErbB receptor signaling.

D. Aunis, A. Bennasroune, S. Dirrig‐Grosch, 2004, Molecular biology of the cell.

Transmembrane domain interactions control biological functions of neuropilin-1.

D. Aunis, L. Roth, S. Dirrig‐Grosch, 2007, Molecular biology of the cell.

Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects

Katharina M. Hembach, V. Rasche, J. Kassubek, 2021, Nature Communications.

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

Xiang-Dong Fu, Hai-Ri Li, A. Ludolph, 2016, The EMBO journal.

A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis

A. Echaniz-Laguna, J. Loeffler, A. Henriques, 2015, EMBO molecular medicine.

Low dietary protein content alleviates motor symptoms in mice with mutant dynactin/dynein-mediated neurodegeneration.

P. Wong, V. Rasche, J. Kassubek, 2015, Human molecular genetics.

Expression and distribution of distinct variants of E-MAP-115 during proliferation and differentiation of human intestinal epithelial cells.

J. Stutzmann, M. Kedinger, M. Vanier, 2003, Cell motility and the cytoskeleton.

Loss of nucleoporin Nup50 is a risk factor for amyotrophic lateral sclerosis

J. Veldink, T. Boeckers, A. Ludolph, 2021, medRxiv.

Longitudinal transcriptomic analysis of altered pathways in a CHMP2Bintron5-based model of ALS-FTD

J. Loeffler, A. Henriques, C. Keime, 2019, Neurobiology of Disease.

Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation

D. Cleveland, S. Megat, C. Lagier-Tourenne, 2020, bioRxiv.

Alteration of the Neuromuscular Junction and Modifications of Muscle Metabolism in Response to Neuron-Restricted Expression of the CHMP2Bintron5 Mutant in a Mouse Model of ALS-FTD Syndrome

J. Loeffler, S. Dirrig‐Grosch, Robin Waegaert, 2022, Biomolecules.

Amyotrophic lateral sclerosis and denervation alter sphingolipids and up-regulate glucosylceramide synthase

M. Spedding, A. Ludolph, A. Echaniz-Laguna, 2015, Human molecular genetics.

Evidence that corticofugal propagation of ALS pathology is not mediated by prion-like mechanism

P. Kessler, M. Birling, C. Rouaux, 2020, Progress in Neurobiology.

Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosis

P. Wong, L. H. van den Berg, J. Veldink, 2016, Acta Neuropathologica.

Integrative genetic analysis illuminates ALS heritability and identifies risk genes

P. Andersen, A. Chiò, J. Veldink, 2023, Nature communications.

Degeneration of serotonin neurons triggers spasticity in amyotrophic lateral sclerosis

C. Rouaux, L. Dupuis, S. Dirrig‐Grosch, 2017, Annals of neurology.

Cocaine induces the expression of homer 1b/c, homer 3a/b, and hsp 27 proteins in rat cerebellum

J. Zwiller, D. Aunis, S. Dirrig‐Grosch, 2007, Synapse.

Low dietary protein content alleviates motor symptoms in mice with mutant dynactin/dynein-mediated neurodegeneration.

P. Wong, V. Rasche, J. Kassubek, 2015, Human Molecular Genetics.

Cortical hyperexcitability in mouse models and patients with amyotrophic lateral sclerosis is linked to noradrenaline deficiency

V. Marchand-Pauvert, C. Rouaux, Y. Goumon, 2024, Science Translational Medicine.