K. Hirashima

I. Jinnai, K. Yoshida, H. Hirota, 1995, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Interleukin-3 and granulocyte colony-stimulating factor as survival factors in murine hemopoietic stem cells in vitro.

K. Ikebuchi, K. Hirashima, Y. Itoh, 1992, International journal of hematology.

Improvement of anemia by recombinant erythropoietin in patients with myelodysplastic syndromes and aplastic anemia.

I. Jinnai, A. Matsuda, M. Bessho, 1990, International journal of cell cloning.

Characterization of a T cell line specific to an anti-Id antibody related to the carbohydrate antigen, sialyl SSEA-1, and the immundominant T cell antigenic site of the antibody.

R. Kannagi, Y. Fukuda, K. Nakao, 1996, Journal of immunology.

Once weekly epoetin beta to increase hemoglobin and improve quality of life in anemic cancer patients receiving chemotherapy: A randomized, double-blind, dose-finding study

N. Saijo, Y. Ohashi, H. Sakai, 2004 .

Treatment of the anemia of aplastic anemia patients with recombinant human erythropoietin in combination with granulocyte colony ‐ stimulating factor: a multicenter randomized controlled study

S. Asano, M. Tomonaga, H. Mizoguchi, 1997, European journal of haematology.

[Plasma cell leukemia associated with monocytosis].

I. Jinnai, A. Matsuda, M. Bessho, 1997, [Rinsho ketsueki] The Japanese journal of clinical hematology.

Trilineage recovery by combination therapy with recombinant human granulocyte colony‐stimulating factor and erythropoietin in patients with aplastic anemia and refractory anemia

Yoshiyuki Kobayashi, I. Jinnai, A. Matsuda, 1994, Stem cells.

Clinical and cytogenetic findings of myelodysplastic syndromes showing hypocellular bone marrow or minimal dysplasia, in comparison with typical myelodysplastic syndromes.

S. Asano, K. Ohyashiki, T. Hotta, 1993, International journal of hematology.

Fucosylated type‐2 chain polylactosamine antigens in human lung cancer

R. Kannagi, Y. Kirihata, K. Hirashima, 1988, International journal of cancer.

Heritable rare fragile sites in patients with leukemia and other hematologic disorders.

M. Bessho, K. Hirashima, E. Takahashi, 1988, Cancer genetics and cytogenetics.

Stimulation of human and murine bone marrow cell colony formation by colony-stimulating factors obtained from the urine of mice bearing leukocytosis-inducing fibrosarcoma.

M. Bessho, K. Hirashima, M. Shikita, 1984, Gan.

Macrophage colony-stimulating factor and granulocyte colony-stimulating factor separated from fibrosarcoma tissue in mice.

M. Bessho, K. Hirashima, M. Shikita, 1984, Gan.

New system for assessing the prognosis of refractory anemia patients

M. Tomonaga, I. Jinnai, S. Honda, 1999, Leukemia.

Long-term Follow-up of Patients with Aplastic Anemia and Refractory Anemia Responding to Combination Therapy with Recombinant Human Granulocyte Colony-Stimulating Factor and Erythropoietin

A. Matsuda, M. Bessho, K. Hirashima, 2002, International journal of hematology.

Multicenter prospective study of clonal complications in adult aplastic anemia patients following recombinant human granulocyte colony-stimulating factor (lenograstim) administration.

S. Asano, M. Tomonaga, M. Kizaki, 2003, International journal of hematology.

Transformation of bilineal hybrid acute leukemia to acute lymphoid leukemia: A case report with serial analyses of cytogenetics and gene rearrangement

I. Jinnai, M. Bessho, K. Hirashima, 1990, American journal of hematology.

Prophylactic and therapeutic effects of oral administration of amphotericin B in mycosis associated with hematologic diseases. Study Group of Mycosis in Hematologic Disease.

H. Mizoguchi, F. Takaku, O. Takatani, 1990, The Japanese journal of antibiotics.

Sialyl SSEA-1 antigen as a carbohydrate marker of human natural killer cells and immature lymphoid cells.

S. Arii, K. Hirashima, K. Ohmori, 1989, Blood.

Effects of recombinant human erythropoietin on anaemic W/Wv and SI/SId mice

M. Higuchi, O. Cynshi, K. Hirashima, 1990, British journal of haematology.

Retroviruses released from a human tumor xenograft in nude mice induce colony-stimulating factor (CSF) activity in human fibroblastic cells

F. Takaku, K. Hirashima, T. Terasima, 1984, Experientia.

Enhancement by transforming growth factor‐β 1 (TGF‐β 1) of the proliferation of leukemic blast progenitors stimulated with IL‐3

T. Morio, N. Nara, M. Bessho, 1991 .

Effects of recombinant human granulocyte colony stimulating factor (rG-CSF) on murine myeloid leukemia: stimulation of proliferation of leukemic cells in vitro and inhibition of development of leukemia in vivo.

S. Asano, M. Ono, K. Hattori, 1989, Leukemia.

Reduced response to granulocyte colony-stimulating factor in W/Wv and Sl/Sld mice.

H. Nomura, K. Hattori, O. Cynshi, 1991, Leukemia.

Poor response of Wv/Wx mice to a grafted neutrophilia-inducing, colony-stimulating-factor-producing tumor.

T. Nakano, M. Bessho, K. Hirashima, 1984, Experimental hematology.

A hematological remission by clonal hematopoiesis after treatment with recombinant human granulocyte-macrophage colony-stimulating factor and erythropoietin in a patient with therapy-related myelodysplastic syndrome.

I. Jinnai, A. Matsuda, M. Bessho, 1992, Leukemia research.

Differential effects of TGF-beta 1 on normal and leukemic human hematopoietic cell proliferation.

I. Jinnai, M. Bessho, K. Hirashima, 1995, Experimental hematology.

Improvement in anemia by recombinant human erythropoietin in patients with myelodysplastic syndrome and aplastic anemia.

I. Jinnai, M. Bessho, K. Hirashima, 1991, Contributions to nephrology.

Successful treatment of multicentric Castleman's disease with intracranial and retroperitoneal tumors.

A. Matsuda, M. Bessho, K. Hirashima, 2001, Internal medicine.

Effects of recombinant human erythropoietin on haemolytic anaemia in mice

M. Higuchi, O. Cynshi, K. Hirashima, 1990, British journal of haematology.

[Aspergillosis of the maxillary sinus in a patient with Ph1 positive acute lymphoblastic leukemia: a case report].

M. Fukuda, I. Jinnai, A. Matsuda, 1990, [Rinsho ketsueki] The Japanese journal of clinical hematology.

A Case of Nodular Subcutaneous Abscesses due to Candida tropicalis Complicated by Acute Myeloid Leukemia

K. Hirashima, T. Sakata, M. Fukuda, 1995 .

[Empiric therapy with fluconazole in granulocytopenic patients with carcinoma or leukemia].

K. Hirashima, T. Abe, R. Kurane, 1994, The Japanese journal of antibiotics.

A Case of Systemic Fusarium solani Infection Complicating Acute Lymphocytic Leukemia

I. Jinnai, M. Bessho, K. Hirashima, 1997 .

Clinical studies on radiation inquires resulting from accidental exposure to an iridium-192 radiographic source.

K. Hirashima, T. Kumatori, H. Sugiyama, 1973, Journal of radiation research.

Chromosome aberrations in persons accidentally exposed to 192Ir gamma-rays.

K. Hirashima, T. Kumatori, T. Ishihara, 1973, Journal of radiation research.

Clinical effect of recombinant human granulocyte colony-stimulating factor (rhG-CSF) on various types of neutropenia including cyclic neutropenia

H. Dohy, S. Asano, S. Eto, 1991, Biotherapy.

Hematological studies of six cases of accidental exposure to an iridium radiographic source.

K. Hirashima, T. Kumatori, T. Ishihara, 1973, Journal of radiation research.

Effect of the Bilateral Section of the Splanchnic Nerve on Erythropoiesis

F. Takaku, K. Hirashima, S. Okinaka, 1961, Nature.

Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13)

N Asou, I. Jinnai, A. Matsuda, 1999, Genes, chromosomes & cancer.

Chromosomal aberrations observed in 52 mouse myeloid leukemias.

K. Yoshida, M. Seki, K. Hirashima, 1983, Cancer research.

High idiotypic connectivity of the VH7183-encoded antibodies directed to a murine embryonic carbohydrate antigen, Lewis Y, as ascertained by syngenic anti-idiotype monoclonal antibodies.

S. Hirohashi, K. Hirashima, S. Kyoizumi, 1990, Journal of immunology.

Effect of recombinant human granulocyte colony-stimulating factor on combination therapy with aztreonam and clindamycin for infections in neutropenic patients with hematologic diseases.

N. Aoki, S. Asano, N. Tsuruoka, 1996, Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases.

Experimental studies on erythropoietin. II. The relationship between juxtaglomerular cells and erythropoietin.

F. Takaku, K. Hirashima, 1962, Blood.

Experimental studies on the mechanism of leukemogenesis following the hemopoietic stem cell kinetics.

M. Bessho, K. Hirashima, 1982, Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society.

Partial deletion of chromosome No. 2 in myelocytic leukemias of irradiated C3H/He and RFM mice.

K. Hirashima, I. Hayata, T. Sado, 1979, Journal of the National Cancer Institute.

Refractory anemia with severe dysplasia: clinical significance of morphological features in refractory anemia

I. Jinnai, S. Honda, A. Matsuda, 1998, Leukemia.

Relationship between fibroblastoid colony-forming units (CFU-f) and hemopoietic precursor cells in normal human bone marrow.

I. Jinnai, N. Nara, M. Bessho, 1984, The International Journal Of Cell Cloning.

Studies on the mechanism of erythropoietin production. I. Effect of unilateral constriction of the renal artery.

F. Takaku, K. Nakao, K. Hirashima, 1962, The Journal of laboratory and clinical medicine.

Prolonged survival of mice with myeloid leukemia by subcutaneous injection of recombinant human G-CSF.

M. Ono, M. Bessho, K. Hirashima, 1989, Leukemia research.

Effects of chloramphenicol on hematopoietic inductive microenvironment.

N. Nara, M. Bessho, K. Hirashima, 1982, Experimental hematology.

Studies on the mechanism of erythropoietin production. II. Effect of bilateral section of the splanchnic nerves.

F. Takaku, K. Hirashima, S. Okinaka, 1962, The Journal of laboratory and clinical medicine.

p53-independent induction of p21 (WAF1/CIP1) during differentiation of HL-60 cells by tumor necrosis factor alpha.

K. Hirashima, I. Murohashi, K. Yoshida, 1996, International journal of hematology.

[De novo CD5-positive diffuse large B-cell lymphoma with leukemic dissemination diagnosed by immunohistochemical examinations of bone marrow clot sections].

A. Matsuda, M. Bessho, K. Hirashima, 2002, [Rinsho ketsueki] The Japanese journal of clinical hematology.

Northern hybridization analysis of VH gene expression in murine monoclonal antibodies directed to cancer-associated ganglioside antigens having various sialic acid linkages.

R. Kannagi, K. Hirashima, A. Takada, 1990, Journal of immunology.

A long term follow-up of a randomized trial comparing interferon-α with busulfan for chronic myelogenous leukemia

T. Naoe, H. Dohy, N. Kamada, 1998 .

Clonal origin of radiation-induced myeloid leukemia in mice with cellular mosaicism.

M. Bessho, K. Hirashima, 1987, Japanese journal of cancer research : Gann.

Single cell origin of radiation-induced thymic lymphoma in mice with cellular mosaicism.

K. Tanaka, H. Tanooka, I. Jinnai, 1984, Gan.

M. Bessho, K. Hirashima, F. Yagasaki, 1998, International journal of hematology.

Efficacy of carboplatin with an MEP (mitoxantrone, etoposide and prednisone) regimen for relapsed and CHOP-resistant diffuse large B-cell lymphomas.

Takashi Takahashi, A. Matsuda, M. Bessho, 2002, Leukemia research.

Effects of Interleukin‐6 and Granulocyte Colony‐stimulating Factor on the Proliferation of Leukemic Blast Progenitors from Acute Myeloblastic Leukemia Patients

T. Morio, N. Aoki, N. Nara, 1990, Japanese journal of cancer research : Gann.

[A randomized controlled study of rG.CSF in patients with neutropenia after induction therapy for acute myelogenous leukemia. (rG.CSF Clinical Study Group)].

S. Asano, M. Tomonaga, R. Ohno, 1995, [Rinsho ketsueki] The Japanese journal of clinical hematology.

[Therapeutic evaluation of combination therapy using human native immunoglobulin preparation for i.v. administration, with antibiotics and G-CSF in severe infections in the field of internal medicine].

S. Asano, H. Mizoguchi, F. Takaku, 1995, Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases.

Reduction of granulocyte-macrophage progenitor cells (CFU-C) and fibroblastoid colony-forming units (CFU-F) by leukemic cells in human and murine leukemia.

I. Jinnai, N. Nara, M. Bessho, 1984, Acta haematologica.

Clinical benefits of lenograstim in patients with neutropenia due to chemotherapy for multiple myeloma (MM)

N. Ogawa, T. Hotta, M. Sawamura, 2001, Supportive Care in Cancer.

[Clinical effect of recombinant human granulocyte colony-stimulating factor on aplastic anemia].

S. Asano, F. Takaku, K. Hirashima, 1990, [Rinsho ketsueki] The Japanese journal of clinical hematology.

MECHANISM OF HEMATOPOIETIC RECOVERY IN THE X-IRRADIATED MOUSE WITH SPLEEN OR ONE LEG SHIELDED.

F. Takaku, K. Nakao, K. Hirashima, 1967 .

Differential response to stem cell factor and Flt3 ligand by the FAB subtype in acute myeloid leukemia clonogenic cells.

Takashi Takahashi, I. Jinnai, A. Matsuda, 2002, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

[Clinical evaluation of combination therapy with sulbactam/cefoperazone and amikacin sulfate for infections associated with hematological disorders].

K. Hirashima, M. Fukuda, 1993, The Japanese journal of antibiotics.

Serum thymidine kinase and soluble interleukin-2 receptor predict recurrence of malignant lymphoma

M. Bessho, K. Hirashima, F. Yagasaki, 2002, Annals of Hematology.

Diagnostic significance of serum soluble transferrin receptors in various anemic diseases: the first multi-institutional joint study in Japan.

Y. Yawata, T. Akizawa, A. Matsuda, 2002, Haematologia.

Modification of X-ray Survival Curves of Stem-cells by Different Doses of Erythropoietin

L. Lajtha, K. Hirashima, D. Porteous, 1965, Nature.

Differential regulation by hematopoietic growth factors of apoptosis and mitosis in acute myeloblastic leukemia cells.

I. Jinnai, K. Yoshida, M. Bessho, 1997, Experimental Hematology.

Effects of recombinant human G-CSF and GM-CSF on primary human leukemic cells.

M. Bessho, K. Hirashima, K. Itoh, 1989, Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society.

[CD7(+) acute myeloid leukemia (M0) associated with a mediastinal bulky mass lesion].

A. Matsuda, M. Bessho, K. Hirashima, 2001, [Rinsho ketsueki] The Japanese journal of clinical hematology.

[Hematological effect of 14 days treatment of recombinant human granulocyte colony-stimulating factor for neutropenia in myelodysplastic syndromes].

S. Asano, F. Takaku, K. Hirashima, 1991, [Rinsho ketsueki] The Japanese journal of clinical hematology.

Effects of Cobalt on Activity of Sheep Erythropoietin in Rat Kidney Homogenates.∗

J. Fisher, K. Hirashima, D. Porteous, 1966, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[Non-Hodgkin's lymphoma complicated by recurrent intractable generalized herpes zoster responsive to long-term acyclovir therapy].

M. Bessho, K. Hirashima, K. Endo, 1999, Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases.

Effect of granulocyte-colony stimulating factor on empiric therapy with flomoxef sodium and tobramycin in febrile neutropenic patients with hematological malignancies

Y. Miura, K. Motoyoshi, K. Hirashima, 1999 .

Effect of granulocyte-colony stimulating factor on empiric therapy with flomoxef sodium and tobramycin in febrile neutropenic patients with hematological malignancies. Kan-etsu Hematological Disease and Infection Study Group.

K. Saito, Y. Miura, T. Naruse, 1999, International journal of hematology.

Unique action of an immunosuppressive agent, deoxyspergualin, on hematopoiesis in mice.

K. Hirashima, A. Ohinata, K. Nemoto, 1997, Experimental Hematology.

[Idiopathic plasmacytic lymphadenopathy with polyclonal hyperimmunoglobulinemia in a patient who died of progressive peripheral polyneuritis and cerebral dysfunction].

I. Jinnai, M. Bessho, K. Hirashima, 1997, [Rinsho ketsueki] The Japanese journal of clinical hematology.

A new cell line of murine myeloid leukemia with A-type phosphoglycerate kinase as marker isoenzyme.

M. Bessho, K. Hirashima, N. Kawai, 1988, Leukemia research.