C. Werno

发表

Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma

S. Haferkamp, K. Dietz, M. Hoffmann, 2018, Nature Communications.

The supernatant of apoptotic cells causes transcriptional activation of hypoxia-inducible factor-1alpha in macrophages via sphingosine-1-phosphate and transforming growth factor-beta.

B. Brüne, Jie Zhou, C. Werno, 2009, Blood.

Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during periods of clinical latency

S. Rose-John, M. Hoffmann, C. Klein, 2020, bioRxiv.

Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency

N. Harbeck, S. Rose-John, M. Hoffmann, 2020, Nature Communications.

Knockout of HIF-1α in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses.

S. Goerdt, B. Brüne, J. Kzhyshkowska, 2010, Carcinogenesis.

A23187, ionomycin and thapsigargin upregulate mRNA of HIF‐1α via endoplasmic reticulum stress rather than a rise in intracellular calcium

B. Brüne, Jie Zhou, C. Werno, 2008, Journal of cellular physiology.

sphingosine-1-phosphate and transforming growth factor-{beta} hypoxia-inducible factor-1{alpha} in macrophages via The supernatant of apoptotic cells causes transcriptional activation of

B. Brüne, Jie Zhou, C. Werno, 2009 .

A combination of hypoxia and lipopolysaccharide activates tristetraprolin to destabilize proinflammatory mRNAs such as tumor necrosis factor-alpha.

B. Brüne, T. Schmid, C. Werno, 2010, The American journal of pathology.

Single-cell microRNA sequencing method comparison and application to cell lines and circulating lung tumor cells

A. Keller, C. Klein, T. Fehlmann, 2021, Nature Communications.

Early dissemination seeds metastasis in breast cancer

Rainer Spang, Tanja Fehm, Brigitte Rack, 2016, Nature.

Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma

S. Haferkamp, K. Dietz, M. Hoffmann, 2018, Nature Communications.

Sphingosine kinase 2 deficient tumor xenografts show impaired growth and fail to polarize macrophages towards an anti‐inflammatory phenotype

B. Brüne, G. Geisslinger, S. Ley, 2009, International journal of cancer.

Roles of hypoxia‐inducible factor‐1α (HIF‐1α) versus HIF‐2α in the survival of hepatocellular tumor spheroids

B. Brüne, T. Schmid, T. Deller, 2010, Hepatology.

Immune Humanization of Immunodeficient Mice Using Diagnostic Bone Marrow Aspirates from Carcinoma Patients

D. Männel, C. Klein, U. Nitsche, 2014, PloS one.

Predicting therapy response by analysis of metastasis founder cells: emerging perspectives for personalized tumor therapy

B. Polzer, C. Werno, K. Honarnejad, 2020 .

Ex vivo expansion of lung cancer‐derived disseminated cancer cells from lymph nodes identifies cells associated with metastatic progression

C. Klein, A. Varadarajan, M. Werner-Klein, 2023, International journal of cancer.

The supernatant of apoptotic cells causes transcriptional activation of hypoxia-inducible factor-1alpha in macrophages via sphingosine-1-phosphate and transforming growth factor-beta.

B. Brüne, Jie Zhou, C. Werno, 2009, Blood.

Sphingosine kinase 2 deficient tumor xenografts show impaired growth and fail to polarize macrophages towards an anti‐inflammatory phenotype

B. Brüne, G. Geisslinger, S. Ley, 2009, International journal of cancer.

Knockout of HIF-1α in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses.

S. Goerdt, B. Brüne, J. Kzhyshkowska, 2010, Carcinogenesis.

HER2 Cellular Localization, Cell-Cell Contacts, and Cell Density Regulate Cancer Cell Plasticity in HER2+ Breast Cancer

Hedayatollah Hosseini, C. Werno, K. Weidele, 2023, bioRxiv.

Lysosomal acid lipase-activity as a novel target to efficiently address triple-negative breast cancer high malignancy

S. Treitschke, C. Werno, K. Weidele, 2023, bioRxiv.

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients.

A. Varadarajan, S. Treitschke, C. Werno, 2024, Molecular oncology.