R. D. Abreu

发表

A point mutation in an invariant splice donor site leads to exon skipping in two unrelated Dutch patients with dihydropyrimidine dehydrogenase deficiency

P. Vreken, A. B. Kuilenburg, R. Meinsma, 1996, Journal of Inherited Metabolic Disease.

Identification of a four-base deletion (delTCAT296–299) in the dihydropyrimidine dehydrogenase gene with variable clinical expression

P. Vreken, A. B. Kuilenburg, R. Meinsma, 1997, Human Genetics.

Molecular Genetics, Biochemistry and Clinical Aspects of Inherited Disorders of Purine and Pyrimidine Metabolism

U. Gresser, R. D. Abreu, R. A. Abreu, 1993, Springer Berlin Heidelberg.

Evidence for an Antagonism Between Caffeine and Adenosine in the Human Cardiovascular System

P. Smits, T. Thien, R. D. Abreu, 1987, Journal of cardiovascular pharmacology.

Real-Time Analysis of Tyrosine Hydroxylase Gene Expression : A Sensitive and Semiquantitative Marker for Minimal Residual Disease Detection of Neuroblastoma 1

M. Ligtenberg, L. Heuvel, C. H. Kaa, 2003 .

Dihydropyrimidine dehydrogenase deficiency Neurological aspects

F. Gabreëls, R. Sengers, J. Braakhekke, 1987, Journal of the Neurological Sciences.

Calcium-phosphate metabolism in autosomal recessive idiopathic strio-pallido-dentate calcinosis and Cockayne's syndrome

F. Gabreëls, H. Thijssen, W. Renier, 1983, Clinical Neurology and Neurosurgery.

Original Paper H eterozygosity for a Point M utation in an Invariant Splice D onor Site o f Dihydropyrim idine Dehydrogenase and Severe 5-Fluorouracil Related Toxicity

R. D. Abreu, A. H. Gennip, A. Amsterdam, 1997 .

Dihydropyrimidine Dehydrogenase Deficiency: Biochemical and Genetic Basis

R. D. Abreu, 1993 .

Elevated urine, blood and cerebrospinal fluid levels of uracil and thymine in a child with dihydrothymine dehydrogenase deficiency.

F. Gabreëls, R. D. De Abreu, R. Sengers, 1984, Clinica chimica acta; international journal of clinical chemistry.

Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene.

P. Vreken, A. V. van Kuilenburg, J. Haasjes, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Pharmacogenetic and clinical aspects of dihydropyrimidine dehydrogenase deficiency

A. B. Kuilenburg, R. D. Abreu, A. H. Gennip, 2003 .

Methotrexate in rheumatoid arthritis: an update with focus on mechanisms involved in toxicity.

H. Blom, R. D. De Abreu, R. Laan, 1998, Seminars in arthritis and rheumatism.

Analysis of Chromosome Aberrations and Sister Chromatid Exchanges in Peripheral Blood Lymphocytes of Newborns after Vitamin K Prophylaxis at Birth

D. Smeets, L. Monnens, G. Merkx, 1991, Pediatric Research.

Purine and Pyrimidine Metabolism and Electrocortical Brain Activity during Hypoxemia in Near-Term Lambs

J. Hopman, M. Bor, R. D. Abreu, 2004, Pediatric Research.

Reference values for amino acids in cerebrospinal fluid of children determined using ion-exchange chromatography with fluorimetric detection.

F. Gabreëls, R. D. De Abreu, L. Monnens, 1989, Clinica chimica acta; international journal of clinical chemistry.

Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency

P. Vreken, M. Durán, E. Holme, 1999, Human Genetics.

Dihydropyrimidinase deficiency, a progressive neurological disorder?

R. D. De Abreu, R. Wevers, J. Rotteveel, 1997, Neuropediatrics.

6-Thioguanine: High-dose 2-H infusions in goats

R. D. Abreu, J. Baal, T. J. Schouten, 2004, Journal of Cancer Research and Clinical Oncology.