A. Fischer

发表

Factor VII gene intronic mutation in a lethal factor VII deficiency: effects on splice-site selection.

S. Amselem, K. Borensztajn, M. Sobrier, 2003, Blood.

Characterization of two novel splice site mutations in human factor VII gene causing severe plasma factor VII deficiency and bleeding diathesis

K. Borensztajn, M. Alhenc-Gelas, A. Fischer, 2002, British journal of haematology.

Perfusion defects after pulmonary embolism: risk factors and clinical significance

L. Trinquart, G. Meyer, S. Couchon, 2010, Journal of thrombosis and haemostasis : JTH.

Characterization of a homozygous Gly11Val mutation in the Gla domain of coagulation factor X.

M. Tagzirt, A. Fischer, O. Chafa, 2009, Thrombosis research.

Therapeutic effect of fucoidan‐stimulated endothelial colony‐forming cells in peripheral ischemia

P. Bruneval, L. David, J. Emmerich, 2012, Journal of thrombosis and haemostasis : JTH.

Mechanism of thrombin inhibition by antithrombin and heparin cofactor II in the presence of heparin.

A. Fischer, J. Tapon-Bretaudière, M. Jozefowicz, 1997, Biomaterials.

Fucoidan Stimulates Monocyte Migration via ERK/p38 Signaling Pathways and MMP9 Secretion

A. Fischer, C. Boisson-Vidal, E. Sapharikas, 2015, Marine drugs.

Evaluation of Prothrombin Complex Concentrate and Recombinant Activated Factor VII to Reverse Rivaroxaban in a Rabbit Model

C. Samama, J. Emmerich, T. Lecompte, 2012, Anesthesiology.

Clinical, biological, and genetic features in an afibrinogenemia patient series in Algeria

P. de Mazancourt, T. Mirault, A. Fischer, 2022, Haemophilia : the official journal of the World Federation of Hemophilia.

Evaluation of recombinant activated factor VII, prothrombin complex concentrate, and fibrinogen concentrate to reverse apixaban in a rabbit model of bleeding and thrombosis.

C. Samama, Anne-Céline Martin, C. Marchand-Leroux, 2013, International journal of cardiology.

Low molecular weight fucoidan and heparin enhance the basic fibroblast growth factor-induced tube formation of endothelial cells through heparan sulfate-dependent alpha6 overexpression.

I. Laurendeau, S. Matou, B. L. Le Bonniec, 2003, Molecular pharmacology.

Low Molecular Weight Fucoidan and Heparin Enhance the Basic Fibroblast Growth Factor-Induced Tube Formation of Endothelial Cells through Heparan Sulfate-Dependent (cid:1) 6 Overexpression

I. Laurendeau, S. Matou, A. Fischer, 2003 .

Modulation of human endothelial cell proliferation and migration by fucoidan and heparin.

D. Letourneur, S. Matou, D Letourneur, 1998, European journal of cell biology.

Effect of an oversulfated exopolysaccharide on angiogenesis induced by fibroblast growth factor-2 or vascular endothelial growth factor in vitro.

S. Matou, A. Fischer, J. Guézennec, 2005, Biochemical pharmacology.

A fucosylated chondroitin sulfate from echinoderm modulates in vitro fibroblast growth factor 2-dependent angiogenesis.

S. Matou, P. Mourão, A. Fischer, 2002, Molecular cancer research : MCR.

Effect of fucoidan on fibroblast growth factor-2-induced angiogenesis in vitro.

S. Matou, A. Fischer, D. Helley, 2002, Thrombosis research.

Venous Antithrombotic and Anticoagulant Activities of a Fucoïdan Fraction

A. Fischer, J. Tapon-Bretaudière, S. Mauray, 1995, Thrombosis and Haemostasis.

The profibrotic cytokine transforming growth factor‐β1 increases endothelial progenitor cell angiogenic properties

I. Bièche, J. Kovacic, P. Gaussem, 2012, Journal of thrombosis and haemostasis : JTH.

Arterial and venous thrombosis is associated with different angiogenic cytokine patterns in patients with antiphospholipid syndrome

J. Emmerich, P. Gaussem, D. Smadja, 2010, Lupus.

Recombinant hirudin (HBW 023): Biological data of ten patients with severe venous thrombo‐embolism

G. Simonneau, A. Camez, F. Parent, 1995, American journal of hematology.

Azacitidine-eligibility in higher-risk myelodysplastic syndromes and chronic myelomonocytic leukaemia: a registry-based study

P. Coppo, A. Fischer, D. Helley, 2013 .

Endothelial dysfunction in systemic lupus patients with low disease activity: evaluation by quantification and characterization of circulating endothelial microparticles, role of anti-endothelial cell antibodies.

P. Youinou, E. Hachulla, Yves Renaudineau, 2010, Rheumatology.

Low-molecular-weight fucoidan enhances the proangiogenic phenotype of endothelial progenitor cells.

D. Benisvy, G. Uzan, F. Zemani, 2005, Biochemical pharmacology.

Characterization, chemical modifications and in vitro anticoagulant properties of an exopolysaccharide produced by Alteromonas infernus.

A. Fischer, D. Helley, C. Sinquin, 2001, Biochimica et biophysica acta.

&agr;6-Integrin Subunit Plays a Major Role in the Proangiogenic Properties of Endothelial Progenitor Cells

B. Gafsou, B. Dizier, A. Fischer, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Anticoagulant activity of dextran derivatives.

E. de Raucourt, F. Chaubet, A. Fischer, 1998, Journal of biomedical materials research.

Thrombin binding properties of insoluble modified polystyrene: Part II.

A. Fischer, J. Tapon-Bretaudière, J. Jozefonvicz, 1988, Thrombosis research.

Thrombin purification by one-step preparative affinity chromatography on modified polystyrenes.

D. Muller, A. Fischer, J. Tapon-Bretaudière, 1986, Journal of chromatography.

Affinity chromatography of thrombin on modified polystyrene resins.

D. Muller, A. Fischer, J. Tapon-Bretaudière, 1986, Journal of chromatography.

Antithrombic properties of insoluble modified polystyrene: Part I.

A. Fischer, J. Tapon-Bretaudière, J. Jozefonvicz, 1984, Thrombosis research.

Effect of Low Molecular Weight Fucoidan and Low Molecular Weight Heparin in a Rabbit Model of Arterial Thrombosis

A. Al Haj Zen, P. Bruneval, A. Lafont, 2008, Journal of Vascular Research.

Severe hypofibrinogenemia associated with bilateral ischemic necrosis of toes and fingers.

A. Fischer, O. Chafa, A. Reghis, 1995, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Human Follicular Fluid Heparan Sulfate Contains Abundant 3-O-Sulfated Chains with Anticoagulant Activity*

Zhenqing Zhang, R. Linhardt, N. W. Shworak, 2008, Journal of Biological Chemistry.

Two novel mutations responsible for hereditary type I protein C deficiency: Characterization by denaturing gradient gel electrophoresis

M. Vidaud, M. Goossens, J. Fiessinger, 1992, Human mutation.

[Hydroxychloroquine: a new therapeutic approach to the thrombotic manifestations of antiphospholipid syndrome].

L. Darnige, A. Fischer, A. Ankri, 2010, La Revue de medecine interne.

Low-Molecular-Weight Fucoidan Induces Endothelial Cell Migration via the PI3K/AKT Pathway and Modulates the Transcription of Genes Involved in Angiogenesis

W. Carpentier, S. Gandrille, F. Grelac, 2015, Marine drugs.

Sunlight-Induced Photochemistry of Humic Substances in Natural Waters: Major Reactive Species

W. J. Cooper, R. Zika, A. Fischer, 1988 .

Variants Using Polymerase Chain Reaction

E. Clauser, M. Aiach, A. Fischer, 2013 .

Platelet dysfunction associated with the novel Trp29Cys thromboxane A2 receptor variant

S. Mundell, A. Mumford, P. Gaussem, 2013, Journal of thrombosis and haemostasis : JTH.

[Thrombopathy induced by selective serotonin reuptake inhibitors: a case report].

L. Amar, P. Gaussem, D. Smadja, 2014, Annales de biologie clinique.

Absence of mutation in the RAB27B gene in patients with platelet delta‐storage pool deficiency

J. Masliah-planchon, J. Callebert, L. Darnige, 2011, European journal of haematology.

Osteoprotegerin, a new actor in vasculogenesis, stimulates endothelial colony‐forming cells properties

I. Bièche, I. Laurendeau, D. Heymann, 2011, Journal of thrombosis and haemostasis : JTH.

“ERS/ATS Task Force onUndifferentiated Forms of CTD-ILD”. An official European RespiratorySociety/American Thoracic Society research statement: interstitial pneumonia withautoimmunefeatures

I. Noth, J. Lee, L. Richeldi, 2015 .

Affinity chromatography of sulphated polysaccharides separately fractionated on antithrombin III and heparin cofactor II immobilized on concanavalin A--sepharose.

V. Sinniger, D. Muller, A. Fischer, 1993, Journal of chromatography.

Relationship between antithrombotic activities of fucans and their structure

F. Chaubet, B. Mulloy, A. Fischer, 2000 .

Homozygous nonsense mutation (Cys72→stop) in the human F7 gene: a not life‐threatening mutation despite the absence of circulating factor VII

A. Fischer, O. Chafa, J. Tapon-Bretaudière, 2005, Journal of thrombosis and haemostasis : JTH.

Tie2-dependent knockout of α6 integrin subunit in mice reduces post-ischaemic angiogenesis.

A. De Arcangelis, B. Dizier, A. Fischer, 2012, Cardiovascular research.

Effect of low‐molecular‐weight fucoidan on experimental arterial thrombosis in the rabbit and rat

A. Fischer, D. Helley, C. Sinquin, 2003, Journal of thrombosis and haemostasis : JTH.

Reversal of anticoagulant effects of apixaban with non-specific prohaemostatic agents: an in vitro study

C. Samama, Anne-Céline Martin, A. Godier, 2013 .

Low molecular weight fucoidan promotes FGF-2-induced vascular tube formation by human endothelial cells, with decreased PAI-1 release and ICAM-1 downregulation.

A. Fischer, D. Helley, D. Chabut, 2004, Thrombosis research.

Diagnostic value of two rapid and individual D-dimer assays in patients with clinically suspected pulmonary embolism: comparison with microplate enzyme-linked immunosorbent assay.

E. de Raucourt, G. Meyer, A. Fischer, 1998, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Polysaccharide labelling: impact on structural and biological properties

A. Fischer, J. Guézennec, C. Sinquin, 2002 .

Effect of oversulfated dermatan sulfate derivatives on platelet aggregation.

M. Dautzenberg, P. Giordano, A. Fischer, 2007, Thrombosis research.

Anticoagulant properties of a fucoïdan fraction.

A. Fischer, J. Tapon-Bretaudière, P. Durand, 1991, Thrombosis research.

Influence of the oversulfation method and the degree of sulfation on the anticoagulant properties of dermatan sulfate derivatives.

M. Dautzenberg, A. Fischer, J. Tapon-Bretaudière, 1990, Thrombosis research.

Comparison between the effect of pentosan polysulphate heparin and antithrombin III injections in antithrombin III deficient patients.

H. Hemker, S. Béguin, J. Goudemand, 1985, Thrombosis research.

Human umbilical vein endothelial cell culture on heparin-like microcarriers.

Y. Sultan, A. Fischer, H. Serne, 1993, Journal of biomedical materials research.

The stability of heparin-coated liposomes in plasma and their effect on its coagulation

D. Letourneur, M. Cansell, A. Fischer, 1998 .

Evaluation of hemostasis and endothelial function in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab

R. Porcher, G. Socié, J. Schved, 2010, Haematologica.

Osteoprotegerin regulates cancer cell migration through SDF-1/CXCR4 axis and promotes tumour development by increasing neovascularization.

D. Heymann, B. Dizier, A. Fischer, 2017, Cancer letters.

Neoangiogenesis induced by progenitor endothelial cells: effect of fucoidan from marine algae.

G. Caligiuri, F. Zemani, A. Fischer, 2007, Cardiovascular & hematological agents in medicinal chemistry.

Interactions of poly(lactic acid) and poly(lactic acid-co-ethylene oxide) nanoparticles with the plasma factors of the coagulation system.

G. Spenlehauer, D. Labarre, A. Fischer, 1997, Biomaterials.

Endothelial colony‐forming cells from patients with paroxysmal nocturnal haemoglobinuria are not PIGA mutated

G. Socié, S. Gandrille, A. Fischer, 2013, British journal of haematology.

A Comparison of Pentosan Polysulphate and Heparin II: Effects of Subcutaneous Injection

P. Gaffney, S. Williams, T. Barrowcliffe, 1982, Thrombosis and Haemostasis.

Eculizumab inhibits clot generation and endothelial dysfunction in patients with paroxysmal nocturnal haemoglobinuria

R. Porcher, G. Socié, J. Matheron, 2010 .

Antithrombotic and Anticoagulant Activities of a Low Molecular Weight Fucoidan by the Subcutaneous Route

A. Fischer, S. Mauray, J. Millet, 1999, Thrombosis and Haemostasis.

A motif within the N-terminal domain of TSP-1 specifically promotes the proangiogenic activity of endothelial colony-forming cells.

L. Juliano, C. Takiya, V. Morandi, 2012, Biochemical pharmacology.

Marine Polysaccharides: A Source of Bioactive Molecules for Cell Therapy and Tissue Engineering

Karim Senni, G. Godeau, Gaston Godeau, 2011, Marine drugs.

Fucoidan, as Heparin, Induces Tissue Factor Pathway Inhibitor Release from Cultured Human Endothelial Cells

S. Matou, A. Fischer, J. Giraux, 1998, Thrombosis and Haemostasis.

Mechanistic study of the proangiogenic effect of osteoprotegerin

D. Heymann, D. Lutomski, C. Deloménie, 2013, Angiogenesis.

Thrombin inhibition by antithrombin in the presence of oversulfated dermatan sulfates.

A. Fischer, M. Jozefowicz, R. Maaroufi, 2006, Carbohydrate research.

Tie2-dependent deletion of α6 integrin subunit in mice reduces tumor growth and angiogenesis.

Zacharie Segaoula, A. De Arcangelis, L. Mauge, 2014, International journal of oncology.

Molecular characterization of antithrombin III (ATIII) variants using polymerase chain reaction. Identification of the ATIII Charleville as an Ala 384 Pro mutation.

E. Clauser, M. Aiach, A. Fischer, 1989, The Journal of clinical investigation.

Anticoagulant activity of dextran derivatives. Part II: Mechanism of thrombin inactivation.

A. Fischer, M. Mauzac, J. Jozefonvicz, 1985, Biomaterials.

Thromboxane synthase mutations in an increased bone density disorder (Ghosal syndrome)

A. Munnich, C. Picard, B. Isidor, 2008, Nature Genetics.

Ex Vivo Priming of Endothelial Progenitor Cells With SDF-1 Before Transplantation Could Increase Their Proangiogenic Potential

F. Fauvel-Lafève, I. Bièche, I. Laurendeau, 2008, Arteriosclerosis, thrombosis, and vascular biology.

Thrombopénie ferriprive : un diagnostic différentiel rare du purpura thrombopénique auto-immun

J. Pouchot, P. Gaussem, J. Arlet, 2010 .

DH, RPL, AMF and GS received educational grants from

L. Darnige, A. Fischer, D. Helley, 2011 .

Prevalence of the FVQ506 (factor V Leiden) mutation in the normal and thrombophilic Algerian population.

A. Fischer, O. Chafa, A. Reghis, 1997, British journal of haematology.

[Prevention of thrombosis by Hemoclar. Preliminary results of a test in a patient with antithrombin III deficiency].

S. Béguin, M. Dautzenberg, A. Fischer, 1982, Revue francaise de transfusion et immuno-hematologie.

A Comparison of Pentosan Polysulphate (SP54) and Heparin I: Mechanism of Action on Blood Coagulation

T. Barrowcliffe, D. Thomas, A. Fischer, 1982, Thrombosis and Haemostasis.

Antithrombin III Alger: A New Homozygous AT III Variant

M. Desnos, S. Béguin, M. Dautzenberg, 1986, Thrombosis and Haemostasis.

Comparative effect of heparin and heparan sulphate on two abnormal antithrombin III type 3 variants

S. Béguin, M. Dautzenberg, A. Fischer, 1987, British journal of haematology.

Pharmacokinetics of warfarin in the nephrotic syndrome and effect on vitamin K-dependent clotting factors.

J. Barré, G. Houin, P. Jungers, 1986, Clinical nephrology.

Respective Roles of Antithrombin III and Alpha 2 Macroglobulin in Thrombin Inactivation

A. Fischer, F. Josso, A. Bros, 1981, Thrombosis and Haemostasis.

Absence of Transplacental Passage of Pentosan Polysulfate During Mid Trimester of Pregnancy

S. Béguin, F. Daffos, F. Forestier, 1986, Thrombosis and Haemostasis.

Behçet Syndrome Associated with Protein S Deficiency

A. Fischer, O. Chafa, M. Benabadji, 1992, Thrombosis and Haemostasis.

A new case of ‘type II’ inherited protein S deficiency

A. Fischer, O. Chafa, M. Benabadji, 1989, British journal of haematology.

Inactivation of thrombin by a fucosylated chondroitin sulfate from echinoderm.

A. Fischer, P. A. Mourão, B. Drouet, 2001, Thrombosis research.

Heparin-like functionalized polymer surfaces: discrimination between catalytic and adsorption processes during the course of thrombin inhibition.

F. Pflüger, D. Labarre, A. Fischer, 1996, Biomaterials.

Plasmatic antiproteinase activity enhancement by insoluble functionalized polystyrene surfaces.

D. Labarre, A. Fischer, M. Jozefowicz, 1990, Biomaterials.

Mechanism of thrombin inhibition by heparin cofactor II in the presence of dermatan sulphates, native or oversulphated, and a heparin-like dextran derivative.

A. Fischer, M. Jozefowicz, R. Maaroufi, 1997, Biomaterials.

Oriented Scanning Is the Leading Mechanism Underlying 5′ Splice Site Selection in Mammals

S. Amselem, K. Borensztajn, P. Duquesnoy, 2006, PLoS genetics.

Monoclonal Immunoglobulins in Haemophiliac Patients with HIV Infection

M. Torchet, C. Gazengel, A. Fischer, 1991, Thrombosis and Haemostasis.

Modulation of Vascular Human Endothelial and Rat Smooth Muscle Cell Growth by a Fucosylated Chondroitin Sulfate from Echinoderm

D. Letourneur, S. Matou, A. Fischer, 2000, Thrombosis and Haemostasis.

Treatment of type III von Willebrand's disease with solvent/detergent-treated factor VIII concentrates.

M. Torchet, C. Rothschild, M. Dautzenberg, 1988, Nouvelle revue francaise d'hematologie.

Factor Xa Acts as a PDGF-Independent Mitogen in Human Vascular Smooth Muscle Cells

K. Schrör, M. Braun, A. Fischer, 2000, Thrombosis and Haemostasis.

Canine heparan sulfate sulfamidase and the molecular pathology underlying Sanfilippo syndrome type A in Dachshunds.

H. Morizono, G. Hoganson, E. Aronovich, 2000, Genomics.

Mechanism of factor IXa inhibition by antithrombin in the presence of unfractionated and low molecular weight heparins and fucoidan.

E. de Raucourt, J. Dachary-Prigent, A. Fischer, 1998, Biochimica et biophysica acta.

Successful use of eculizumab in a patient with post‐transplant thrombotic microangiopathy

G. Socié, P. Coppo, V. Frémeaux-Bacchi, 2013, British journal of haematology.

Caractéristiques clinico-biologiques des patients avec thrombocytémie essentielle en fonction de leur statut mutationnel JAK2 ou CALR : étude monocentrique de 40 patients et revue de la littérature

S. Gandrille, L. Darnige, A. Fischer, 2015 .

Antiphospholipid antibodies in patients with paroxysmal nocturnal haemoglobinuria receiving eculizumab

G. Socié, L. Darnige, A. Fischer, 2011, British journal of haematology.

Fas expression in DLBCL

L. Darnige, A. Fischer, S. Clauser, 2007, American journal of hematology.

Direct observation of phototransients in natural waters

D. Kliger, T. Mill, A. Fischer, 1985 .

The prevalence of selective IgA deficiency in type 1 diabetes mellitus

C. Boitard, R. Liblau, J. Bach, 1992, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Platelet microparticles: a potential predictive factor of survival in hormone-refractory prostate cancer patients treated with docetaxel-based chemotherapy.

S. Oudard, F. Scotté, A. Fischer, 2009, European urology.

[Hirudin. A new and promising anticoagulant from leech].

M. Aiach, A. Fischer, 1991, La Revue du praticien.

[Antiphospholipid syndrome diagnosis: an update].

L. Darnige, A. Fischer, B. Visseaux, 2011, Annales de biologie clinique.

Use of a factor XI concentrate in three severe factor XI-deficient patients.

E. de Raucourt, A. Fischer, M. Goudemand, 1995, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

RISK FACTORS AND CLINICAL SIGNIFICANCE OF RESIDUAL PERFUSION DEFECTS AFTER SYMPTOMATIC PULMONARY EMBOLISM

G. Meyer, A. Fischer, H. Sors, 2007 .

Exopolysaccharides produced by bacteria isolated from deep-sea hydrothermal vents: new agents with therapeutic potential

A. Fischer, P. Zanchetta, J. Guézennec, 2004 .

Mechanistic study of the proangiogenic effect of osteoprotegerin

D. Heymann, D. Lutomski, C. Deloménie, 2013, Angiogenesis.

Heparin-induced thrombocytopenia with thrombotic complications during prophylactic treatment with low-molecular-weight heparin.

C. Vinsonneau, E. de Raucourt, G. Meyer, 1996, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Inherited factor VII deficiency: identification of two novel mutations (A191V and T239P) in the catalytic domain.

K. Borensztajn, H. Wajcman, B. L. Le Bonniec, 2005, Thrombosis research.

Prevalence of the Prothrombin Gene 20210A Mutation in Thrombophilic and Healthy Algerian Subjects

A. Fischer, O. Chafa, A. Reghis, 1999, Thrombosis and Haemostasis.

The in vitro and in vivo effects of a low-molecular-weight fucoidan on the osteogenic capacity of human adipose-derived stromal cells.

P. Corre, B. Dizier, A. Fischer, 2014, Tissue Engineering. Part A.

LETTER TO THE EDITOR Effect of low-molecular-weight fucoidan on experimental arterial thrombosis in the rabbit and rat

A. Fischer, D. Helley, C. Sinquin, 2003 .

[Microbial polysaccharides of marine origin and their potential in human therapeutics].

A. Fischer, P. Zanchetta, J. Guézennec, 2004, Pathologie-biologie.

A two adenine insertion polymorphism in the 3’ untranslated region of factor VII gene is associated with peripheral arterial disease but not with venous thrombosis

J. Reny, J. Emmerich, A. Fischer, 2007, Thrombosis and Haemostasis.

Markers of hemostatic system activation in pulmonary embolism. Changes during and after cessation of anticoagulant treatment.

P. Landais, E. de Raucourt, G. Meyer, 2000, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Poster session 2

Hugo A. Katus, V. V. Miroshnikova, Paolo Dario, 2004, EP Europace.

Prothrombin Poissy: a new variant of human prothrombin

M. Dumont, A. Fischer, J. Chassevent, 1987, British journal of haematology.

Use of a polysaccharide sulfate of low molecular weight for obtaining a drug active against vascular thrombosis

D. Letourneur, A. Fischer, P. Durand, 1999 .