C. Notley

发表

Aberrant Splicing and Premature Termination of Transcription of the FVIII Gene as a Cause of Severe Canine Hemophilia A: Similarities with the Intron 22 Inversion Mutation in Human Hemophilia

A. Giles, D. Lillicrap, C. Hough, 2002, Thrombosis and Haemostasis.

Cell type-specific regulation of von Willebrand factor expression by the E4BP4 transcriptional repressor.

D. Lillicrap, C. Hough, C. Notley, 2005, Blood.

Cell type – specific regulation of von Willebrand factor expression by the E 4 BP 4 transcriptional repressor

D. Lillicrap, C. Hough, C. Notley, 2005 .

The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels.

A. Paterson, R. Montgomery, P. James, 2013, Blood.

Omental implantation of BOECs in hemophilia dogs results in circulating FVIII antigen and a complex immune response.

M. Ozelo, V. Arruda, A. Winterborn, 2014, Blood.

circulating FVIII antigen and a complex immune response Omental implantation of BOECs in hemophilia dogs results in

M. Ozelo, V. Arruda, A. Winterborn, 2014 .

Stabilin‐2 deficiency increases thrombotic burden and alters the composition of venous thrombi in a mouse model

D. Lillicrap, C. Notley, L. Swystun, 2021, Journal of thrombosis and haemostasis : JTH.

The scavenger receptor SCARA5 is an endocytic receptor for von Willebrand factor expressed by littoral cells in the human spleen

K. Tryggvason, D. Lillicrap, J. Lai, 2019, Journal of thrombosis and haemostasis : JTH.

The mutational spectrum of type 1 von Willebrand disease: Results from a Canadian cohort study.

L. O'Brien, J. Leggo, M. Othman, 2007, Blood.

The Canine Factor VIII cDNA and 5’ Flanking Sequence

A. Giles, D. Lillicrap, C. Hough, 1998, Thrombosis and Haemostasis.

Systemic delivery of an adenoviral vector encoding canine factor VIII results in short-term phenotypic correction, inhibitor development, and biphasic liver toxicity in hemophilia A dogs.

M. Kaleko, S. Connelly, D. Lillicrap, 2001, Blood.

Abnormal von Willebrand factor secretion, factor VIII stabilization and thrombus dynamics in type 2N von Willebrand disease mice

D. Lillicrap, J. Mewburn, C. Notley, 2017, Journal of thrombosis and haemostasis : JTH.

Role of the liver-enriched transcription factor hepatocyte nuclear factor 1 in transcriptional regulation of the factor V111 gene

D. Lillicrap, C. Mueller, C. Notley, 1996, Molecular and cellular biology.

Endothelial characteristics in healthy endothelial colony forming cells; generating a robust and valid ex vivo model for vascular disease

E. Weijers, J. Eikenboom, P. James, 2020, Journal of thrombosis and haemostasis : JTH.

Androgen effects on factor IX expression: in‐vitro and in‐vivo studies in mice

D. Lillicrap, C. Cameron, C. Notley, 1998, British journal of haematology.

Frequency of Platelet type versus Type 2B von Willebrand Disease

M. Ozelo, J. Leggo, M. Othman, 2011, Thrombosis and Haemostasis.

The Factor VIII Acute Phase Response Requires the Participation of NFκB and C/EBP

D. Lillicrap, S. Tinlin, C. Notley, 2000, Thrombosis and Haemostasis.

The genetics of Canadian type 3 von Willebrand disease: further evidence for co‐dominant inheritance of mutant alleles

V. Blanchette, J. Leggo, P. James, 2013, Journal of thrombosis and haemostasis : JTH.

Challenges in defining type 2M von Willebrand disease: results from a Canadian cohort study

P. James, D. Lillicrap, M. Poon, 2007, Journal of thrombosis and haemostasis : JTH.

Founder von Willebrand factor haplotype associated with type 1 von Willebrand disease.

J. Sutherland, L. O'Brien, M. Othman, 2003, Blood.

Heterogeneity and reciprocity of FVIII and VWF expression, and the response to shear stress in cultured human endothelial cells

D. Lillicrap, C. Hough, C. Notley, 2022, Journal of thrombosis and haemostasis : JTH.

Functional characterization of a 13-bp deletion (c.-1522_-1510del13) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease.

D. Hampshire, M. Othman, A. Parker, 2010, Blood.

The effect of exercise on von Willebrand factor and ADAMTS‐13 in individuals with type 1 and type 2B von Willebrand disease

P. Lenting, P. James, D. Lillicrap, 2007, Journal of thrombosis and haemostasis : JTH.

ADAMTS13 cleavage efficiency is altered by mutagenic and, to a lesser extent, polymorphic sequence changes in the A1 and A2 domains of von Willebrand factor

L. O'Brien, D. Lillicrap, C. Notley, 2008, British journal of haematology.

The canine factor VIII 3'-untranslated region and a concatemeric hepatocyte nuclear factor 1 regulatory element enhance factor VIII transgene expression in vivo.

D. Lillicrap, C. Hough, A. Killoran, 2002, Human gene therapy.

Genetic linkage and association analysis in type 1 von Willebrand disease: results from the Canadian Type 1 VWD Study

A. Paterson, L. O'Brien, J. Leggo, 2006, Journal of thrombosis and haemostasis : JTH.

biphasic liver toxicity in hemophilia A dogs results in short-term phenotypic correction, inhibitor development, and Systemic delivery of an adenoviral vector encoding canine factor VIII

M. Kaleko, S. Connelly, D. Lillicrap, 2013 .

In vivo evaluation of an adenoviral vector encoding canine factor VIII: high-level, sustained expression in hemophiliac mice.

D. Kayda, M. Kaleko, S. Connelly, 1999, Human gene therapy.

The endothelial lectin clearance receptor CLEC4M binds and internalizes factor VIII in a VWF‐dependent and independent manner

P. James, D. Lillicrap, J. Lai, 2019, Journal of thrombosis and haemostasis : JTH.

A novel type 2A von Willebrand factor mutation located at the last nucleotide of exon 26 (3538G>A) causes skipping of 2 nonadjacent exons.

L. O'Brien, P. James, D. Lillicrap, 2004, Blood.

Influence of a GT repeat element on shear stress responsiveness of the VWF gene promoter

L. O'Brien, D. Lillicrap, C. Hough, 2008, Journal of thrombosis and haemostasis : JTH.

Identification and functional characterization of a novel 27-bp deletion in the macroglycopeptide-coding region of the GPIBA gene resulting in platelet-type von Willebrand disease.

H. White, C. Byrne, M. Othman, 2004, Blood.

The Endothelial Lectin Receptor CLEC4M Internalizes Factor VIII and Von Willebrand Factor Via a Clathrin-Coated Pit-Dependent Mechanism

P. James, D. Lillicrap, C. Notley, 2013 .

The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity

S. Goerdt, R. Montgomery, P. James, 2018, The Journal of clinical investigation.

Expanded phenotype–genotype correlations in a pediatric population with type 1 von Willebrand disease

V. Blanchette, M. Carcao, P. James, 2011, Journal of thrombosis and haemostasis : JTH.

Pathologic mechanisms of type 1 VWD mutations R1205H and Y1584C through in vitro and in vivo mouse models.

D. Lillicrap, Kate Sponagle, C. Notley, 2011, Blood.

Human von Willebrand Disease Mutations in Mouse von Willebrand Factor Alter Its Cleavage by ADAMTS13.

D. Lillicrap, C. Notley, C. Hegadorn, 2007 .

Expanded phenotype–genotype correlations in a pediatric population with type 1 von Willebrand disease

C. Notley, M. Rand, J. Robertson, 2011, Journal of thrombosis and haemostasis : JTH.

The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels.

D. Lillicrap, Kate Sponagle, N. Rydz, 2013, Blood.