Youhou Kang

发表

Four PSM/SH2-B Alternative Splice Variants and Their Differential Roles in Mitogenesis*

Youping Deng, N. Yousaf, Youhou Kang, 2001, The Journal of Biological Chemistry.

Syntaxin-1A Binds the Nucleotide-binding Folds of Sulphonylurea Receptor 1 to Regulate the KATP Channel*

N. Cui, Youhou Kang, Ewa A Pasyk, 2004, Journal of Biological Chemistry.

Botulinum Neurotoxin A and Neurotoxin E Cleavage Products of Synaptosome-Associated Protein of 25 kd Exhibit Distinct Actions on Pancreatic Islet &bgr;-Cell Kv2.1 Channel Gating

C. Elias, Y. Leung, Youhou Kang, 2008, Pancreas.

Munc18b Is a Major Mediator of Insulin Exocytosis in Rat Pancreatic β-Cells

H. Kasai, M. Kauppi, V. Olkkonen, 2013, Diabetes.

Dual role of VAMP8 in regulating insulin exocytosis and islet β cell growth.

M. Woo, M. Wheeler, E. Allister, 2012, Cell metabolism.

Pancreas-specific SNAP23 depletion prevents pancreatitis by attenuating pathological basolateral exocytosis and formation of trypsin-activating autolysosomes

T. Liang, P. Roche, J. Manuel, 2020, Autophagy.

Truncation of SNAP-25 reduces the stimulatory action of cAMP on rapid exocytosis in insulin-secreting cells.

L. Eliasson, J. Vikman, Youhou Kang, 2009, American journal of physiology. Endocrinology and metabolism.

Effects of Selective Endocrine or Exocrine Induction of AR42J on SNARE and Munc18 Protein Expression

I. Kojima, Y. Eto, Youhou Kang, 2002, Pancreas.

The Actions of a Novel Potent Islet β-Cell–Specific ATP-Sensitive K+ Channel Opener Can Be Modulated by Syntaxin-1A Acting on Sulfonylurea Receptor 1

P. Wahl, C. Elias, Youhou Kang, 2007, Diabetes.

SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes.

J. Pessin, T. Liang, C. Ostenson, 2020, JCI insight.

Kv2.1 clusters on β-cell plasma membrane act as reservoirs that replenish pools of newcomer insulin granule through their interaction with syntaxin-3

T. Liang, A. Hardy, Youhou Kang, 2018, The Journal of Biological Chemistry.

Munc18b Increases Insulin Granule Fusion, Restoring Deficient Insulin Secretion in Type-2 Diabetes Human and Goto-Kakizaki Rat Islets with Improvement in Glucose Homeostasis

T. Liang, C. Ostenson, S. Sugita, 2017, EBioMedicine.

Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells

T. Liang, E. Chapman, Youhou Kang, 2016, Diabetes.

New Roles of Syntaxin-1A in Insulin Granule Exocytosis and Replenishment*

M. Wheeler, T. Liang, K. J. Prentice, 2016, The Journal of Biological Chemistry.

Syntaxin-3 Binds and Regulates Both R- and L-Type Calcium Channels in Insulin-Secreting INS-1 832/13 Cells

T. Liang, Liangyi Chen, Youhou Kang, 2016, PloS one.

Syntaxin-4 mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose-stimulated insulin secretion in human pancreatic beta cells

T. Liang, Youhou Kang, H. Gaisano, 2015, Diabetologia.

Munc18c mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose stimulated insulin secretion in human pancreatic beta-cells

T. Liang, Youhou Kang, H. Gaisano, 2015, Molecular metabolism.

Phosphatidylinositol 4,5-Biphosphate (PIP2) Modulates Interaction of Syntaxin-1A with Sulfonylurea Receptor 1 to Regulate Pancreatic β-Cell ATP-sensitive Potassium Channels*

Zhong-Ping Feng, T. Liang, Youhou Kang, 2014, The Journal of Biological Chemistry.

Phosphatidylinositol 4,5-biphosphate (PIP2) modulates syntaxin-1A binding to sulfonylurea receptor 2A to regulate cardiac ATP-sensitive potassium (KATP) channels.

Zhong-Ping Feng, S. Shyng, T. Liang, 2014, Journal of molecular and cellular cardiology.

ATP Modulates Interaction of Syntaxin-1A with Sulfonylurea Receptor 1 to Regulate Pancreatic β-Cell KATP Channels*

S. Shyng, Nathan Chang, T. Liang, 2010, The Journal of Biological Chemistry.

Syntaxin-1A inhibition of P-1075, cromakalim, and diazoxide actions on mouse cardiac ATP-sensitive potassium channel.

Youhou Kang, H. Gaisano, Hui Sun, 2008, Cardiovascular research.

Role of the exchange protein directly activated by cyclic adenosine 5'-monophosphate (Epac) pathway in regulating proglucagon gene expression in intestinal endocrine L cells.

T. Jin, Peixiang Wang, M. Rahimi, 2006, Endocrinology.

Syntaxin-1A Interacts with Distinct Domains within Nucleotide-binding Folds of Sulfonylurea Receptor 1 to Inhibit β-Cell ATP-sensitive Potassium Channels*

Zhong-Ping Feng, Nathan Chang, T. Liang, 2011, The Journal of Biological Chemistry.

Pancreatitis-Induced Depletion of Syntaxin 2 Promotes Autophagy and Increases Basolateral Exocytosis.

T. Liang, P. Thorn, Abrahim I. Orabi, 2018, Gastroenterology.

Exocyst Sec5 Regulates Exocytosis of Newcomer Insulin Granules Underlying Biphasic Insulin Secretion

T. Liang, Youhou Kang, H. Gaisano, 2013, PloS one.

SNAP-25 inhibits L-type Ca2+ channels in feline esophagus smooth muscle cells.

N. Diamant, Youhou Kang, H. Gaisano, 2003, Biochemical and biophysical research communications.

The Neuronal Ca2+ Sensor Protein Visinin-like Protein-1 Is Expressed in Pancreatic Islets and Regulates Insulin Secretion*

Catherine B. Chan, F. Dai, M. Wheeler, 2006, Journal of Biological Chemistry.

Synaptosome-associated protein of 25 kilodaltons modulates Kv2.1 voltage-dependent K(+) channels in neuroendocrine islet beta-cells through an interaction with the channel N terminus.

P. MacDonald, M. Wheeler, J. Lakey, 2002, Molecular endocrinology.

Syntaxin-1A inhibits KATP channels by interacting with specific conserved motifs within sulfonylurea receptor 2A.

Zhong-Ping Feng, T. Liang, Youhou Kang, 2011, Journal of molecular and cellular cardiology.

Direct Interaction of Target SNAREs with the Kv2.1 Channel

M. Linial, D. Chikvashvili, Sharon Tsuk, 2003, Journal of Biological Chemistry.

Syntaxin-1A Inhibits Cardiac KATP Channels by Its Actions on Nucleotide Binding Folds 1 and 2 of Sulfonylurea Receptor 2A*

P. Light, Y. Leung, Youhou Kang, 2004, Journal of Biological Chemistry.

Plasma membrane flipping of Syntaxin-2 regulates its inhibitory action on insulin granule exocytosis

Youhou Kang, H. Gaisano, Fei Kang, 2022, Nature Communications.

RalA GTPase Tethers Insulin Granules to L‐ and R‐Type Calcium Channels Through Binding α2δ‐1 Subunit

D. James, T. Liang, S. Chidambaram, 2013, Traffic.

Syntaxin-1A Actions on Sulfonylurea Receptor 2A Can Block Acidic pH-induced Cardiac KATP Channel Activation*

Y. Leung, A. Tinker, Youhou Kang, 2006, Journal of Biological Chemistry.

VAMP8 Deletion Delays the Onset of Streptozotocin-Induced Hyperglycemia

M. Woo, Youhou Kang, H. Gaisano, 2012 .

MODAL REGULATION OF CHANNEL ACTIVATION AND INACTIVATION GATING

M. Linial, D. Chikvashvili, Sharon Tsuk, 2003 .

SNAREing voltage-gated K+ and ATP-sensitive K+ channels: tuning beta-cell excitability with syntaxin-1A and other exocytotic proteins.

Y. Leung, Youhou Kang, H. Gaisano, 2007, Endocrine reviews.

H 3 Domain of Syntaxin 1 A Inhibits KATP Channels by Its Actions on the Sulfonylurea Receptor 1 Nucleotide-Binding Folds-1 and-2 *

P. Wahl, Y. Leung, N. Cui, 2004 .

Syntaxin 1A Binds to the Cytoplasmic C Terminus of Kv2.1 to Regulate Channel Gating and Trafficking*

Sharon Tsuk, I. Lotan, Y. Leung, 2003, The Journal of Biological Chemistry.

Regional differences in L-type Ca2+ channel expression in feline lower esophageal sphincter.

N. Diamant, Youhou Kang, H. Gaisano, 2004, American journal of physiology. Gastrointestinal and liver physiology.

SUMOylation Regulates Insulin Exocytosis Downstream of Secretory Granule Docking in Rodents and Humans

P. MacDonald, X. Dai, C. Hajmrle, 2011, Diabetes.

An Exploratory Study of the Association between KCNB1 rs1051295 and Type 2 Diabetes and Its Related Traits in Chinese Han Population

Hong Wang, J. Zhang, Qingxuan Lai, 2013, PloS one.

SNAREing Voltage-Gated K+ and ATP-Sensitive K+ Channels: Tuning β-Cell Excitability with Syntaxin-1A and Other Exocytotic Proteins.

Y. Leung, Youhou Kang, H. Gaisano, 2007, Endocrine reviews.

H3 Domain of Syntaxin 1A Inhibits KATP Channels by Its Actions on the Sulfonylurea Receptor 1 Nucleotide-Binding Folds-1 and -2*

P. Wahl, Y. Leung, N. Cui, 2004, Journal of Biological Chemistry.

The 25-kDa Synaptosome-associated Protein (SNAP-25) Binds and Inhibits Delayed Rectifier Potassium Channels in Secretory Cells*

N. Diamant, W. Trimble, A. Salapatek, 2002, The Journal of Biological Chemistry.

Open form of syntaxin-1A is a more potent inhibitor than wild-type syntaxin-1A of Kv2.1 channels.

Y. Leung, Youhou Kang, L. Sheu, 2005, The Biochemical journal.

Syntaxin 2 Acts as Inhibitory SNARE for Insulin Granule Exocytosis

Li Xie, Tao Liang, T. Liang, 2017, Diabetes.

Modulation of Kv2.1 channel gating and TEA sensitivity by distinct domains of SNAP-25.

Y. Leung, Youhou Kang, H. Gaisano, 2006, The Biochemical journal.

Cab45b, a Munc18b-interacting Partner, Regulates Exocytosis in Pancreatic beta-Cells

V. Olkkonen, Nathan Chang, Youhou Kang, 2009 .

Distinct modulation of Kv1.2 channel gating by wild type, but not open form, of syntaxin-1A.

N. Diamant, Y. Leung, Youhou Kang, 2007, American journal of physiology. Gastrointestinal and liver physiology.

Distinct modulation of Kv 1 . 2 channel gating by wild type , but not open form , of syntaxin-1 A

N. Diamant, Y. Leung, Youhou Kang, 2007 .

Syntaxin-3 regulates newcomer insulin granule exocytosis and compound fusion in pancreatic beta cells

D. Zhu, Seungmee Park, S. Sugita, 2013, Diabetologia.

The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function

P. MacDonald, X. Dai, C. Hajmrle, 2012, Diabetologia.