R. Mckay

发表

Deletion of individual exons and induction of soluble murine interleukin-5 receptor-alpha chain expression through antisense oligonucleotide-mediated redirection of pre-mRNA splicing.

J. Karras, B. Monia, N. Dean, 2000, Molecular pharmacology.

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting.

Mark Graham, Susan F Murray, B. Monia, 2006, Cell metabolism.

Hepatic and glucagon-like peptide-1-mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors.

N. Porksen, J. Gromada, B. Berridge, 2004, The Journal of clinical investigation.

Protein kinase C delta is a prosurvival factor in human breast tumor cell lines.

L. Miraglia, J. Strobl, R. Mckay, 2003, Molecular cancer therapeutics.

Targeting Foxo1 in Mice Using Antisense Oligonucleotide Improves Hepatic and Peripheral Insulin Action

G. Shulman, J. Geisler, B. Monia, 2006, Diabetes.

Antisense inhibition of membrane-bound human interleukin-5 receptor-alpha chain does not affect soluble receptor expression and induces apoptosis in TF-1 cells.

J. Karras, B. Monia, N. Dean, 2000, Antisense & nucleic acid drug development.

Role of resistin in diet-induced hepatic insulin resistance.

B. Monia, E. D. Muse, L. Rossetti, 2004, The Journal of clinical investigation.

Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice.

B. Monia, N. Dean, S. Murray, 2002, Diabetes.

Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonism.

B. Monia, S. Bhanot, M. Michael, 2005, Diabetes.

Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice

B. Monia, Xing Yu, S. Pandey, 2005, Hepatology.

Inhibition of c-Jun N-terminal kinase 1, but not c-Jun N-terminal kinase 2, suppresses apoptosis induced by ischemia/reoxygenation in rat cardiac myocytes.

B. Monia, C. Cioffi, R. Mckay, 2001, Molecular pharmacology.

Specific Reduction of Hepatic Glucose 6-Phosphate Transporter-1 Ameliorates Diabetes while Avoiding Complications of Glycogen Storage Disease*

B. Monia, S. Booten, S. Murray, 2007, Journal of Biological Chemistry.

FFA-induced hepatic insulin resistance in vivo is mediated by PKCδ, NADPH oxidase, and oxidative stress.

I. G. Fantus, S. Najjar, S. Bhanot, 2014, American journal of physiology. Endocrinology and metabolism.

Inhibition of Antigen-Induced Eosinophilia and Late Phase Airway Hyperresponsiveness by an IL-5 Antisense Oligonucleotide in Mouse Models of Asthma

J. Karras, B. Monia, N. Dean, 2000, The Journal of Immunology.

Mouse Models of Asthma by an IL-5 Antisense Oligonucleotide in and Late Phase Airway Hyperresponsiveness Inhibition of Antigen-Induced Eosinophilia

J. Karras, B. Monia, N. Dean, 2000 .

Severe impairment in liver insulin signaling fails to alter hepatic insulin action in conscious mice.

B. Monia, E. D. Muse, L. Rossetti, 2005, The Journal of clinical investigation.

In Vitro and In Vivo Inhibition of Interleukin (IL)-5–Mediated Eosinopoiesis by Murine IL-5R α Antisense Oligonucleotide

J. Karras, B. Monia, C. Walker, 2001 .

Antisense oligonucleotides as inhibitors of genes that regulate AP-1: pharmacology and clinical development.

N. Dean, J. Holmlund, R. Mckay, 1998, Antisense & nucleic acid drug development.

PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice

J. Waring, R. Ulrich, S. Crosby, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Discovery and analysis of antisense oligonucleotide activity in cell culture.

B. Monia, E. Koller, B. Baker, 2001, Methods.

Enhanced activity of an antisense oligonucleotide targeting murine protein kinase C-alpha by the incorporation of 2'-O-propyl modifications.

E. Lesnik, N. Dean, M. Graham, 1996, Nucleic acids research.

Characterization of a Potent and Specific Class of Antisense Oligonucleotide Inhibitor of Human Protein Kinase C-α Expression*

L. Miraglia, N. Dean, L. Cummins, 1999, The Journal of Biological Chemistry.

STAT3 regulates the growth and immunoglobulin production of BCL(1) B cell lymphoma through control of cell cycle progression.

J. Karras, B. Monia, T. Lu, 2000, Cellular immunology.

Reduction of Low Molecular Weight Protein-tyrosine Phosphatase Expression Improves Hyperglycemia and Insulin Sensitivity in Obese Mice*

B. Monia, Xing Yu, S. Pandey, 2007, Journal of Biological Chemistry.

Inhibition of protein tyrosine phosphatase-1B with antisense oligonucleotides improves insulin sensitivity and increases adiponectin concentrations in monkeys.

B. Monia, S. Booten, S. Murray, 2009, Endocrinology.

Reversal of cisplatin resistance in human ovarian cancer cell lines by a c-jun antisense oligodeoxynucleotide (ISIS 10582): evidence for the role of transcription factor overexpression in determining resistant phenotype.

P. O'dwyer, K. Yao, B. Monia, 2002, Biochemical pharmacology.

Protein Kinase C Is a Prosurvival Factor in Human Breast Tumor Cell Lines 1

L. Miraglia, J. Strobl, R. Mckay, 2003 .

Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice.

B. Monia, Xing Yu, S. Pandey, 2005 .

Inhibition of protein tyrosine phosphatase-1B with antisense oligonucleotides improves insulin sensitivity and increases adiponectin concentrations in monkeys.

B. Monia, S. Booten, S. Murray, 2009, Endocrinology.

Targeting Hepcidin with Antisense Oligonucletides Improves Anemia Endpoints in Mice.

B. Monia, A. Watt, G. Hung, 2006 .

Hepatic and glucagon-like peptide-1-mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors.

J. Gromada, B. Monia, S. Bhanot, 2004, The Journal of clinical investigation.