G. M. Donné-op den Kelder

发表

Generalized cytochrome P450-mediated oxidation and oxygenation reactions in aromatic substrates with activated N-H, O-H, C-H, or S-H substituents.

L. Koymans, N. Vermeulen, J. T. te Koppele, 1993, Xenobiotica; the fate of foreign compounds in biological systems.

A homology model for rat mu class glutathione S-transferase 4-4.

N. Vermeulen, M. D. de Groot, G. M. Donné-op den Kelder, 1996, Chemical research in toxicology.

A theoretical study on the metabolic activation of paracetamol by cytochrome P-450: indications for a uniform oxidation mechanism.

J. H. van Lenthe, L. Koymans, N. Vermeulen, 1988, Chemical research in toxicology.

A quantum chemical explanation of the antioxidant activity of flavonoids.

A. Bast, M. D. de Groot, W. van der Vijgh, 1996, Chemical research in toxicology.

Cytochromes P450: their active-site structure and mechanism of oxidation.

L. Koymans, N. Vermeulen, G. M. Donné-op den Kelder, 1993, Drug metabolism reviews.

Localization of the second calcium ion binding site in porcine and equine phospholipase A2.

M. Egmond, G. de Haas, G. M. Donné-op den Kelder, 1983, Biochemistry.

Is there a difference in the affinity of histamine H1 receptor antagonists for CNS and peripheral receptors? An in vitro study.

A. Bast, H. Timmerman, G. M. Donné-op den Kelder, 1993, European journal of pharmacology.

Physicochemical studies on the interaction of pancreatic phospholipase A2 with a micellar substrate analogue.

M. Egmond, G. de Haas, P. Sauve, 1981, Biochemistry.

Metabolite predictions for para-substituted anisoles based on ab initio complete active space self-consistent field calculations.

J. H. van Lenthe, N. Vermeulen, M. D. de Groot, 1995, Chemical research in toxicology.

A new model for the agonistic binding site on the histamine H2-receptor: the catalytic triad in serine proteases as a model for the binding site of histamine H2-receptor agonists.

E J Baerends, E. Baerends, H. Timmerman, 1994, Journal of molecular graphics.

Binding of porcine pancreatic phospholipase A2 to various micellar substrate analogues. Involvement of histidine-48 and aspartic acid-49 in the binding process.

M. Egmond, G. de Haas, R. Dijkman, 1981, Biochemistry.

Does the ternary complex act as a secondary proton pump and a GTP synthase?

H. Timmerman, G. M. Donné-op den Kelder, P. Nederkoorn, 1995, Trends in pharmacological sciences.

A theoretical study concerning the mode of interaction of the histamine H2-agonist dimaprit.

H. Timmerman, E. Haaksma, G. M. Donné-op den Kelder, 1992, Journal of molecular graphics.

Mapping of the beta 2-adrenoceptor on Chang liver cells. Differences between high- and low-affinity receptor states.

H. Timmerman, G. M. Donné-op den Kelder, B. Rademaker, 1988, Journal of Medicinal Chemistry.

A predictive model for substrates of cytochrome P450-debrisoquine (2D6).

S A van Acker, L. Koymans, N. Vermeulen, 1992, Chemical research in toxicology.

The histamine H1-receptor antagonist binding site. A stereoselective pharmacophoric model based upon (semi-)rigid H1-antagonists and including a known interaction site on the receptor.

J. Venhorst, H. Timmerman, G M Donné-Op den Kelder, 1995, Journal of medicinal chemistry.

A three-dimensional protein model for human cytochrome P450 2D6 based on the crystal structures of P450 101, P450 102, and P450 108.

N. Vermeulen, M. D. de Groot, M J de Groot, 1996, Chemical research in toxicology.