John L Hopper

发表

High performance computing enabling exhaustive analysis of higher order single nucleotide polymorphism interaction in Genome Wide Association Studies

Matthias Reumann, Justin Zobel, Benjamin Goudey, 2015, Health Inf. Sci. Syst..

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade.

Jane E. Carpenter, Kyriaki Michailidou, France Labrèche, 2014, Human molecular genetics.

An open-source, integrated pedigree data management and visualization tool for genetic epidemiology.

John L Hopper, Enes Makalic, Adrian Bickerstaffe, 2018, International journal of epidemiology.

International Network of Twin Registries (INTR): Building a Platform for International Collaboration

John L Hopper, Jennifer R Harris, Jaakko Kaprio, 2014, Twin Research and Human Genetics.

Towards more effective and equitable genetic testing for BRCA1 and BRCA2 mutation carriers

John L Hopper, Carmel Apicella, Graham G Giles, 2008, Journal of Medical Genetics.

Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource

John L Hopper, Edward Edkins, Phyllis N Butow, 2006, Breast Cancer Research.

Mammographic Density and Candidate Gene Variants: A Twins and Sisters Study

John L Hopper, Lyle C Gurrin, Gillian S Dite, 2007, Cancer Epidemiology Biomarkers & Prevention.

Multiple loci with different cancer specificities within the 8q24 gene desert.

John L Hopper, Honglin Song, Thibaud Koessler, 2008, Journal of the National Cancer Institute.

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.

Peter Kraft, Todd L Edwards, Nazneen Rahman, 2016, Cancer discovery.

The Breast Cancer Family Registry: an infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer

Norman Boyd, John L Hopper, Irene L Andrulis, 2004, Breast Cancer Research.

Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer.

Julian Peto, Sergi Castellví-Bel, Jean-Baptiste Cazier, 2008, Human molecular genetics.

BRCA1/2-negative, high-risk breast cancers (BRCAX) for Asian women: genetic susceptibility loci and their potential impacts

John L Hopper, Jisun Kim, Joohon Sung, 2018, Scientific Reports.

Cirrus: An Automated Mammography-Based Measure of Breast Cancer Risk Based on Textural Features

Benjamin Goudey, John L Hopper, Enes Makalic, 2018, JNCI cancer spectrum.

A variant in FTO shows association with melanoma risk not due to BMI

Marko Hočevar, Florence Demenais, Kari Stefansson, 2013, Nature Genetics.

Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer.

Alun Thomas, Sue Healey, John L Hopper, 2009, American journal of human genetics.

A genome-wide linkage study of mammographic density, a risk factor for breast cancer

Celia MT Greenwood, John L Hopper, Irene L Andrulis, 2011, Breast Cancer Research.

Mammographic density: a heritable risk factor for breast cancer.

John L Hopper, Martin J Yaffe, Jennifer Stone, 2009, Methods in molecular biology.

Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers.

Christiana Kartsonaki, Mads Thomassen, Etienne Rouleau, 2011, Human molecular genetics.

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

Mads Thomassen, Nina Ditsch, Vijai Joseph, 2012, Breast Cancer Research.

19p13.1 is a triple-negative-specific breast cancer susceptibility locus.

Daniel J. Park, Julian Peto, Kamila Czene, 2012, Cancer research.

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers.

Mads Thomassen, Nina Ditsch, Dieter Niederacher, 2009, Human molecular genetics.

Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study.

John D Potter, Shinichi Hayashi, John L Hopper, 2007, Gastroenterology.

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

Wei Lu, Wei Zheng, Mads Thomassen, 2013, Nature Genetics.

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers.

Dong Liang, Patrick Neven, Harvey Risch, 2016, Journal of the National Cancer Institute.

Familial risks, early-onset breast cancer, and BRCA1 and BRCA2 germline mutations.

John L Hopper, Gillian S Dite, Graham G Giles, 2003, Journal of the National Cancer Institute.

Commentary: Case-control-family designs: a paradigm for future epidemiology research?

John L Hopper, 2003, International journal of epidemiology.

Heritability of mammographic density, a risk factor for breast cancer.

David Tritchler, John L Hopper, Gillian S Dite, 2002, The New England journal of medicine.

Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants.

Mathieu Lemire, John D Potter, Conghui Qu, 2015, JAMA.

Gene–Environment Interaction Involving Recently Identified Colorectal Cancer Susceptibility Loci

Mathieu Lemire, Jing Ma, Mengmeng Du, 2014, Cancer Epidemiology, Biomarkers & Prevention.

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

Christiana Kartsonaki, Mads Thomassen, Julian Peto, 2010, Nature Genetics.

Colon Cancer Family Registry: An International Resource for Studies of the Genetic Epidemiology of Colon Cancer

John D Potter, John L Hopper, John Baron, 2007, Cancer Epidemiology Biomarkers & Prevention.

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.

Patrick Neven, Päivi Heikkilä, Giu-Cheng Hsu, 2011, Human molecular genetics.

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

Peter Kraft, Anssi Auvinen, Henrik Gronberg, 2013, Nature Genetics.

Risk Prediction Models for Colorectal Cancer: A Review

John L Hopper, Aung Ko Win, J. Hopper, 2011, Cancer Epidemiology, Biomarkers & Prevention.

Determining the familial risk distribution of colorectal cancer: a data mining approach

Rowena Chau, John L Hopper, Loic Le Marchand, 2015, Familial Cancer.

Using mammographic density to predict breast cancer risk: dense area or percentage dense area

Stephen W Duffy, John L Hopper, Jennifer Stone, 2010, Breast Cancer Research.

Using Mammographic Density to Improve Breast Cancer Screening Outcomes

Anne M Kavanagh, Carolyn Nickson, John L Hopper, 2008, Cancer Epidemiology Biomarkers & Prevention.

The Heritability of Mammographically Dense and Nondense Breast Tissue

John L Hopper, Gillian S Dite, Graham G Giles, 2006, Cancer Epidemiology Biomarkers & Prevention.

Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk: A case-control study in unselected white European populations

John D Potter, David Forman, John L Hopper, 2018, PloS one.

A Multifactorial Likelihood Model for MMR Gene Variant Classification Incorporating Probabilities Based on Sequence Bioinformatics and Tumor Characteristics: A Report from the Colon Cancer Family Registry

Steven Gallinger, John L Hopper, Sean V Tavtigian, 2013, Human mutation.

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

Julian Peto, Henry Völzke, Sergi Castellví-Bel, 2008, Nature Genetics.

Breast-cancer risk in families with mutations in PALB2.

Nazneen Rahman, Katri Pylkäs, Arto Mannermaa, 2014, The New England journal of medicine.

Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium.

Michael Jones, Nazneen Rahman, Michael Bremer, 2011, Human molecular genetics.

A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium.

Julian Peto, Kyriaki Michailidou, Thomas Brüning, 2014, Human molecular genetics.

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

Patrick Neven, Peter Kraft, Nazneen Rahman, 2015 .

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

Steven Gallinger, Peter Kraft, Nazneen Rahman, 2016, Cancer research.

Double-Strand Break Repair Gene Polymorphisms and Risk of Breast or Ovarian Cancer

John L Hopper, Georgia Chenevix-Trench, Graham G Giles, 2005, Cancer Epidemiology Biomarkers & Prevention.

Analyzing the Etiology of Benign Rolandic Epilepsy: A Multicenter Twin Collaboration

John L Hopper, Roger L Milne, Linda A Corey, 2006, Epilepsia.

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers.

Wei Lu, Päivi Heikkilä, Peter Kraft, 2013, American journal of human genetics.

Genome-wide association studies identify four ER negative–specific breast cancer risk loci

Patrick Neven, Michael Jones, Wei Lu, 2013, Nature Genetics.

Five endometrial cancer risk loci identified through genome-wide association analysis

Hui Zhao, Mark McEvoy, Julian Peto, 2016, Nature Genetics.

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

Patrick Neven, Chiun-Sheng Huang, Julian Peto, 2014, Breast Cancer Research.

Use of molecular tumor characteristics to prioritize mismatch repair gene testing in early-onset colorectal cancer.

John L Hopper, Graham G Giles, Melissa C Southey, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.

Suzanne Chambers, Peter Kraft, Anssi Auvinen, 2013, Human molecular genetics.

Consequences of germline variation disrupting the constitutional translational initiation codon start sites of MLH1 and BRCA2: Use of potential alternative start sites and implications for predicting variant pathogenicity

John L Hopper, Kathy Tucker, Bryony A Thompson, 2015, Molecular carcinogenesis.

Discovery of common and rare genetic risk variants for colorectal cancer

Mathieu Lemire, Steven Gallinger, Michael Wainberg, 2018, Nature Genetics.

Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction.

Mads Thomassen, Etienne Rouleau, Dieter Niederacher, 2010, Cancer research.

Classifying MLH1 and MSH2 variants using bioinformatic prediction, splicing assays, segregation, and tumor characteristics

John L Hopper, Sean V Tavtigian, Michael O Woods, 2009, Human mutation.

Mammographic breast density and breast cancer: evidence of a shared genetic basis.

Nazneen Rahman, Kyriaki Michailidou, Kamila Czene, 2012, Cancer research.

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

Dong Liang, Jane E. Carpenter, Peter Kraft, 2016, Journal of Medical Genetics.

Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data

Mathieu Lemire, Steven Gallinger, Anshul Kundaje, 2017, PloS one.

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2

Mads Thomassen, Stephen Fox, Dieter Niederacher, 2011, Breast Cancer Research.

Accuracy of Risk Estimates from the iPrevent Breast Cancer Risk Assessment and Management Tool

Jack Cuzick, Gord Glendon, Mary Beth Terry, 2019, JNCI cancer spectrum.

Population-based family studies in genetic epidemiology

John L Hopper, Douglas F Easton, D. Bishop, 2005, The Lancet.

Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.

Michael Jones, Julian Peto, Thomas Brüning, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

Wei Lu, Nina Ditsch, Julian Peto, 2013, American journal of human genetics.

Breast cancer prognosis in BRCA1 and BRCA2 mutation carriers: an International Prospective Breast Cancer Family Registry population-based cohort study.

John L Hopper, Irene L Andrulis, Carmel Apicella, 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

10-year performance of four models of breast cancer risk: a validation study.

Gord Glendon, Mary Beth Terry, John L Hopper, 2019, The Lancet. Oncology.

Risks of Lynch syndrome cancers for MSH6 mutation carriers.

Finlay Macrae, John L Hopper, Loic Le Marchand, 2010, Journal of the National Cancer Institute.

Identification of nine new susceptibility loci for endometrial cancer

Peter Kraft, Mark McEvoy, Julian Peto, 2018, Nature Communications.

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

Suzanne Chambers, Peter Kraft, Henrik Gronberg, 2011, Nature Genetics.

Genome-wide association analysis identifies three new breast cancer susceptibility loci

Michael Jones, Nazneen Rahman, Daniel J. Park, 2012, Nature Genetics.

Clinical classification of BRCA1 and BRCA2 DNA sequence variants: the value of cytokeratin profiles and evolutionary analysis--a report from the kConFab Investigators.

Sue Healey, John L Hopper, Georgia Chenevix-Trench, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness.

Stefania Tommasi, Laura Cortesi, Mads Thomassen, 2019, Cancer research.