Matthew W. Frank

发表

ATF6α induces XBP1-independent expansion of the endoplasmic reticulum

P. Fagone, R. Kaufman, J. W. Brewer, 2009, Journal of Cell Science.

A Pseudomonas aeruginosa transcription factor that senses fatty acid structure

C. Rock, Yong-mei Zhang, Kun Zhu, 2007, Molecular microbiology.

Host Fatty Acid Utilization by Staphylococcus aureus at the Infection Site

C. Rock, C. Subramanian, J. Rosch, 2020, mBio.

A fatty acid-binding protein of Streptococcus pneumoniae facilitates the acquisition of host polyunsaturated fatty acids

C. Rock, S. White, J. Gullett, 2019, The Journal of Biological Chemistry.

Auxotrophs Do Not Proliferate in Mice Staphylococcus aureus Fatty Acid

C. Rock, J. Rosch, Joshua B Parsons, 2014 .

FabH Mutations Confer Resistance to FabF-Directed Antibiotics in Staphylococcus aureus

C. Rock, Joshua B Parsons, Matthew W. Frank, 2014, Antimicrobial Agents and Chemotherapy.

Staphylococcus aureus Fatty Acid Auxotrophs Do Not Proliferate in Mice

C. Rock, J. Rosch, Joshua B Parsons, 2013, Antimicrobial Agents and Chemotherapy.

Membrane Disruption by Antimicrobial Fatty Acids Releases Low-Molecular-Weight Proteins from Staphylococcus aureus

C. Rock, Joshua B Parsons, Matthew W. Frank, 2012, Journal of bacteriology.

Coordinate Regulation of Phospholipid Biosynthesis and Secretory Pathway Gene Expression in XBP-1(S)-induced Endoplasmic Reticulum Biogenesis*

J. W. Brewer, G. L. Buldak, S. Jackowski, 2007, Journal of Biological Chemistry.

Role of Fatty Acid Kinase in Cellular Lipid Homeostasis and SaeRS-Dependent Virulence Factor Expression in Staphylococcus aureus

C. Rock, C. Subramanian, Matthew W. Frank, 2017, mBio.

Branched-chain amino acid metabolism controls membrane phospholipid structure in Staphylococcus aureus

C. Rock, Matthew W. Frank, S. Whaley, 2021, The Journal of biological chemistry.

Serum Opacity Factor, a Streptococcal Virulence Factor That Binds to Apolipoproteins A-I and A-II and Disrupts High Density Lipoprotein Structure*

C. Rock, Yong-mei Zhang, H. Courtney, 2006, Journal of Biological Chemistry.

Elimination of the CDP-ethanolamine Pathway Disrupts Hepatic Lipid Homeostasis*

C. Rock, S. Jackowski, Matthew W. Frank, 2009, The Journal of Biological Chemistry.

The CDP-Ethanolamine Pathway Regulates Skeletal Muscle Diacylglycerol Content and Mitochondrial Biogenesis without Altering Insulin Sensitivity.

A. Russell, P. Meikle, M. Febbraio, 2015, Cell metabolism.

Oleate Hydratase (OhyA) Is a Virulence Determinant in Staphylococcus aureus

C. Rock, J. Rosch, Matthew W. Frank, 2021, Microbiology spectrum.

Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation.

C. Rock, S. Ogden, Miriam E. Dillard, 2017, Cell reports.

Maternal bile acid transporter deficiency promotes neonatal demise

C. Rock, Fei Li, G. Neale, 2015, Nature Communications.

Homeostasis Pathway Disrupts Hepatic Lipid Elimination of the CDP-ethanolamine Regulation , and Signaling : Lipids and Lipoproteins : Metabolism

C. Rock, Matthew W. Frank, Pamela, 2009 .

Biochemical characterization of the first step in sulfonolipid biosynthesis in Alistipes finegoldii

C. Rock, Darcie J. Miller, Matthew W. Frank, 2022, The Journal of biological chemistry.

Biochemical characterization of the ﬁ rst step in sulfonolipid biosynthesis in Alistipes ﬁ negoldii

C. Rock, Darcie J. Miller, Matthew W. Frank, 2022 .

PqsD Is Responsible for the Synthesis of 2,4-Dihydroxyquinoline, an Extracellular Metabolite Produced by Pseudomonas aeruginosa*

C. Rock, Yong-mei Zhang, Kun Zhu, 2008, Journal of Biological Chemistry.

Lysophospholipid Flipping across the Escherichia coli Inner Membrane Catalyzed by a Transporter (LplT) Belonging to the Major Facilitator Superfamily*

C. Rock, M. Saier, Zhongge Zhang, 2005, Journal of Biological Chemistry.

Chlamydia trachomatis Scavenges Host Fatty Acids for Phospholipid Synthesis via an Acyl-Acyl Carrier Protein Synthetase*

C. Rock, Matthew W. Frank, Jiangwei Yao, 2015, The Journal of Biological Chemistry.

Fatty acid activation and utilization by Alistipes finegoldii, a representative Bacteroidetes resident of the human gut microbiome

C. Rock, Matthew W. Frank, Jiangwei Yao, 2019, Molecular microbiology.

Relief of CoA sequestration and restoration of mitochondrial function in a mouse model of propionic acidemia

C. Rock, C. Subramanian, S. White, 2022, Journal of inherited metabolic disease.

Pantothenate kinase activation relieves coenzyme A sequestration and improves mitochondrial function in mice with propionic acidemia

C. Rock, C. Subramanian, S. White, 2021, Science Translational Medicine.

Pyruvate Oxidase as a Critical Link between Metabolism and Capsule Biosynthesis in Streptococcus pneumoniae

C. Rock, Ti-Cheng Chang, A. Iverson, 2016, PLoS pathogens.

Acyl Carrier Protein Is a Cellular Target for the Antibacterial Action of the Pantothenamide Class of Pantothenate Antimetabolites*

C. Rock, Yong-mei Zhang, S. Jackowski, 2004, Journal of Biological Chemistry.

Chlamydia trachomatis Relies on Autonomous Phospholipid Synthesis for Membrane Biogenesis*♦

C. Rock, Matthew W. Frank, Jiangwei Yao, 2015, The Journal of Biological Chemistry.

A thioesterase bypasses the requirement for exogenous fatty acids in the plsX deletion of Streptococcus pneumoniae

C. Rock, J. Schalkwijk, M. Jonge, 2015, Molecular microbiology.

RelA Mutant Enterococcus faecium with Multiantibiotic Tolerance Arising in an Immunocompromised Host

C. Rock, V. Cooper, J. Rubnitz, 2017, mBio.

Activation of Exogenous Fatty Acids to Acyl-Acyl Carrier Protein Cannot Bypass FabI Inhibition in Neisseria*

C. Rock, Richard E. Lee, Matthew W. Frank, 2015, The Journal of Biological Chemistry.

A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance

C. Rock, J. Rosch, B. Jana, 2022, Nature Communications.

Physiological roles of the pantothenate kinases.

S. Jackowski, Jina Wang, Matthew W. Frank, 2014, Biochemical Society transactions.

A bacterial pan-genome makes gene essentiality strain-dependent and evolvable

C. Rock, Defne Surujon, J. Rosch, 2022, bioRxiv.

Phospholipid Biosynthesis Program Underlying Membrane Expansion during B-lymphocyte Differentiation*

P. Fagone, S. Jackowski, Jina Wang, 2007, Journal of Biological Chemistry.

Acyl-chain selectivity and physiological roles of Staphylococcus aureus fatty acid–binding proteins

C. Rock, C. Subramanian, S. White, 2018, The Journal of Biological Chemistry.

Probucol therapy overcomes the reproductive defect in CTP: phosphocholine cytidylyltransferase beta2 knockout mice.

J. Rehg, K. Murti, S. Jackowski, 2007, Biochimica et biophysica acta.

Malonyl-acyl carrier protein decarboxylase activity promotes fatty acid and cell envelope biosynthesis in Proteobacteria

C. Rock, C. Subramanian, Matthew W. Frank, 2021, The Journal of biological chemistry.

Structure and mechanism of Staphylococcus aureus oleate hydratase (OhyA)

C. Rock, B. Young, Matthew W. Frank, 2020, The Journal of biological chemistry.

The genome of a Bacteroidetes inhabitant of the human gut encodes a structurally distinct enoyl-acyl carrier protein reductase (FabI)

C. Rock, J. Seetharaman, Darcie J. Miller, 2020, The Journal of Biological Chemistry.

Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors

Chitra Subramanian, C. Rock, C. Subramanian, 2011, Proceedings of the National Academy of Sciences.

A therapeutic approach to pantothenate kinase associated neurodegeneration

C. Rock, C. Subramanian, S. White, 2018, Nature Communications.

Cardiac PANK1 Deletion Exacerbates Ventricular Dysfunction During Pressure Overload.

B. Merkely, S. Jackowski, M. Pólos, 2021, American journal of physiology. Heart and circulatory physiology.

Incorporation of extracellular fatty acids by a fatty acid kinase‐dependent pathway in Staphylococcus aureus

C. Rock, C. Subramanian, Joshua B Parsons, 2014, Molecular microbiology.

Oleate hydratase from Staphylococcus aureus protects against palmitoleic acid, the major antimicrobial fatty acid produced by mammalian skin

C. Rock, C. Subramanian, Matthew W. Frank, 2019, The Journal of Biological Chemistry.

A pantothenate kinase-deficient mouse model reveals a gene expression program associated with brain coenzyme a reduction.

C. Rock, C. Subramanian, S. Jackowski, 2020, Biochimica et biophysica acta. Molecular basis of disease.

Role of the pyruvate metabolic network on carbohydrate metabolism and virulence in Streptococcus pneumoniae

C. Rock, H. Echlin, J. Rosch, 2020, Molecular microbiology.

Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy.

C. Rock, S. Jackowski, Matthew W. Frank, 2015, Molecular genetics and metabolism.

A short-chain acyl-CoA synthetase that supports branched-chain fatty acid synthesis in Staphylococcus aureus

C. Rock, Matthew W. Frank, S. Whaley, 2023, The Journal of biological chemistry.

A therapeutic approach to pantothenate kinase associated neurodegeneration

C. Rock, C. Subramanian, S. White, 2018, Nature Communications.

Quantification of Coenzyme A in Cells and Tissues.

C. Rock, C. Subramanian, S. Jackowski, 2019, Journal of visualized experiments : JoVE.

Enoyl-Acyl Carrier Protein Reductase I (FabI) Is Essential for the Intracellular Growth of Listeria monocytogenes

C. Rock, Matthew W. Frank, Jiangwei Yao, 2016, Infection and Immunity.

The CDP-Ethanolamine Pathway Regulates Skeletal Muscle Diacylglycerol Content and Mitochondrial Biogenesis without Altering Insulin Sensitivity.

A. Russell, P. Meikle, M. Febbraio, 2015, Cell metabolism.

Activation of Exogenous Fatty Acids to Acyl-Acyl Carrier Protein Cannot Bypass FabI Inhibition in Neisseria*

C. Rock, Richard E. Lee, Matthew W. Frank, 2015, The Journal of Biological Chemistry.

The Bacillus subtilis cell envelope stress-inducible ytpAB operon modulates membrane properties and contributes to bacitracin resistance

J. Helmann, C. Subramanian, Matthew W. Frank, 2024, bioRxiv.