D. Pan

发表

Retroviral transduction and expansion of peripheral blood lymphocytes for the treatment of mucopolysaccharidosis type II, Hunter's syndrome

D. Stroncek, A. Hubel, C. Whitley, 1999, Transfusion.

Combined ultrafiltration-transduction in a hollow-fiber bioreactor facilitates retrovirus-mediated gene transfer into peripheral blood lymphocytes from patients with mucopolysaccharidosis type II.

C. Whitley, D. Stroncek, R. Shankar, 1999, Human gene therapy.

Retroviral transduction of peripheral blood leukocytes in a hollow‐ fiber bioreactor

D. Stroncek, C. Whitley, D. Stroncek, 1997, Transfusion.

Real-time quantitative polymerase chain reaction to assess gene transfer.

K. Becker, C. Whitley, D. Pan, 1999, Human gene therapy.

Comprehensive evaluation of blood-brain barrier-forming micro-vasculatures: Reference and marker genes with cellular composition

D. Pan, Salim S. El-Amouri, Mei Dai, 2018, PloS one.

New function of a well‐known promoter: Enhancer activity of minimal CMV promoter enables efficient dual‐cassette transgene expression

D. Pan, Xiaohong Wang, Yi Lin, 2021, The journal of gene medicine.

K-Cl Cotransporter Gene Expression during Human and Murine Erythroid Differentiation*

D. Mount, Daren Wang, C. Hübner, 2011, The Journal of Biological Chemistry.

Normalization and improvement of CNS deficits in mice with Hurler syndrome after long-term peripheral delivery of BBB-targeted iduronidase.

R. Brady, D. Pan, Salim S. El-Amouri, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Loss of BRUCE reduces cellular energy level and induces autophagy by driving activation of the AMPK-ULK1 autophagic initiating axis

Qi-En Wang, T. Herzog, D. Pan, 2019, PloS one.

Getting the Most: Enhancing Efficacy by Promoting Erythropoiesis and Thrombopoiesis after Gene Therapy in Mice with Hurler Syndrome

D. Pan, Salim S. El-Amouri, Mei Dai, 2018, Molecular therapy. Methods & clinical development.

Correction of metabolic, craniofacial, and neurologic abnormalities in MPS I mice treated at birth with adeno-associated virus vector transducing the human alpha-L-iduronidase gene.

W. Low, R. McIvor, C. Whitley, 2004, Molecular therapy : the journal of the American Society of Gene Therapy.

"Supercharged Cells" for delivery of recombinant human iduronate-2-sulfatase.

S. Braun, R. McIvor, C. Whitley, 2000, Molecular genetics and metabolism.

In vivo gene transfer into adult stem cells in unconditioned mice by in situ delivery of a lentiviral vector.

C. von Kalle, D. Pan, Todd Schuesler, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

Hematopoietic Stem cell transplantation and lentiviral vector‐based gene therapy for Krabbe's disease: Present convictions and future prospects

E. Bongarzone, D. Moore, T. Kafri, 2016, Journal of neuroscience research.

Improved gene transfer and normalized enzyme levels in primitive hematopoietic progenitors from patients with mucopolysaccharidosis type I using a bioreactor

D. Stroncek, C. Whitley, D. Pan, 2004, The journal of gene medicine.

Cell- and gene-based therapeutic approaches for neurological deficits in Mucopolysaccharidoses

D. Pan, 2014 .

Retroviral-mediated transfer of the iduronate-2-sulfatase gene into lymphocytes for treatment of mild Hunter syndrome (mucopolysaccharidosis type II).

R. Latchaw, R. McIvor, B. Blazar, 1996, Human gene therapy.

Molecular Genetic Defect Underlying a-L-lduronidase Pseudodeficiency

E. Aronovich, C. Whitley, D. Pan, 2007 .

Reprogramming erythroid cells for lysosomal enzyme production leads to visceral and CNS cross-correction in mice with Hurler syndrome

Wei Zhang, Daren Wang, P. Malik, 2009, Proceedings of the National Academy of Sciences.

Co‐expression of MGMTP140K and α‐L‐iduronidase in primary hepatocytes from mucopolysaccharidosis type I mice enables efficient selection with metabolic correction

Daren Wang, D. Pan, D. N. Worsham, 2008, The journal of gene medicine.

Molecular genetic defect underlying alpha-L-iduronidase pseudodeficiency.

E. Aronovich, C. Whitley, D. Pan, 1996, American journal of human genetics.

A multifaceted evaluation of microgliosis and differential cellular dysregulation of mammalian target of rapamycin signaling in neuronopathic Gaucher disease

D. Pan, Yi Lin, Zhenting Zhang, 2022, Frontiers in Molecular Neuroscience.

In situ (in vivo) gene transfer into murine bone marrow stem cells.

D. Pan, 2009, Methods in molecular biology.

Platelets are efficient and protective depots for storage, distribution, and delivery of lysosomal enzyme in mice with Hurler Syndrome

R. Brady, D. Pan, Salim S. El-Amouri, 2014, Proceedings of the National Academy of Sciences.

Retroviral vector design studies toward hematopoietic stem cell gene therapy for mucopolysaccharidosis type I

R. McIvor, E. Aronovich, C. Whitley, 2000, Gene Therapy.

Cell- and gene-based therapeutic approaches for neurological deficits in mucopolysaccharidoses.

D. Pan, 2011, Current pharmaceutical biotechnology.

Intraosseous delivery of lentiviral vectors targeting factor VIII expression in platelets corrects murine hemophilia A.

D. Rawlings, C. Miao, D. Pan, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

Biodistribution and toxicity studies of VSVG-pseudotyped lentiviral vector after intravenous administration in mice with the observation of in vivo transduction of bone marrow.

I. Verma, T. Kafri, W. Kaemmerer, 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

A convenient approach to facilitate monitoring Gaucher disease progression and therapeutic response.

Ying Sun, K. Setchell, D. Wattanasirichaigoon, 2017, The Analyst.

Closed hollow‐fiber bioreactor: a new approach to retroviral vector production

C. Whitley, D. Pan, D Pan, 1999, The journal of gene medicine.

Preclinical studies of lymphocyte gene therapy for mild Hunter syndrome (mucopolysaccharidosis type II).

S. Braun, R. McIvor, E. Aronovich, 1996, Human gene therapy.

Mobilization and transduction of peripheral blood progenitor cells in patients with mucopolysaccharidosis I.

A. Hubel, C. Whitley, D. Stroncek, 1998, Journal of hematotherapy.

Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen

David A. Williams, Yi Zheng, J. Cancelas, 2010, Haematologica.

Craniofacial Abnormalities in a Murine Knock-Out Model of Mucopolysaccharidosis I H: A Computed Tomography and Anatomic Study

W. Low, C. Whitley, D. Pan, 2004, The Journal of craniofacial surgery.

Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood–brain barrier

C. Kuan, R. Brady, Daren Wang, 2013, Proceedings of the National Academy of Sciences.

Progression of Behavioral and CNS Deficits in a Viable Murine Model of Chronic Neuronopathic Gaucher Disease

Ying Sun, G. Grabowski, B. Liou, 2016, PloS one.

RUNX represses Pmp22 to drive neurofibromagenesis

E. Boscolo, N. Ratner, E. Dombi, 2019, Science Advances.

Secreted Luciferase for In Vivo Evaluation of Systemic Protein Delivery in Mice

C. Miao, D. Pan, Salim S. El-Amouri, 2012, Molecular Biotechnology.

miR-143 Regulates Lysosomal Enzyme Transport across the Blood-Brain Barrier and Transforms CNS Treatment for Mucopolysaccharidosis Type I.

Mei Xin, D. Pan, Kevin Rose, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Progression of Behavioral and CNS Deficits in a Viable Murine Model of Chronic Neuronopathic Gaucher Disease

Ying Sun, G. Grabowski, B. Liou, 2016, PloS one.

Rational Design of Gene Therapy Vectors

Chen Ling, Hildegard Büning, Dao Pan, 2019, Molecular therapy. Methods & clinical development.

Intraosseous delivery of lentiviral vectors targeting factor VIII expression in platelets corrects murine hemophilia A.

D. Rawlings, C. Miao, D. Pan, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.