G. Linton

发表

Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease.

S. Holland, T. Fleisher, C. Maack, 1997, Proceedings of the National Academy of Sciences of the United States of America.

The K-562 cell model for analysis of neutrophil NADPH oxidase function.

H. Malech, T. Leto, G. Linton, 2007, Methods in molecular biology.

Genetic correction of p67phox deficient chronic granulomatous disease using peripheral blood progenitor cells as a target for retrovirus mediated gene transfer.

H. Malech, N. Whiting-Theobald, G. Linton, 1997, Blood.

Polyclonal long-term MFGS-gp91phox marking in rhesus macaques after nonmyeloablative transplantation with transduced autologous peripheral blood progenitor cells.

A. Farese, T. MacVittie, U. Choi, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

Reversion mutations in patients with leukocyte adhesion deficiency type-1 (LAD-1).

S. Holland, T. Fleisher, S. Rosenzweig, 2008, Blood.

Gene therapy improves immune function in preadolescents with X-linked severe combined immunodeficiency.

J. Puck, Joie Davis, A. Hsu, 2007, Blood.

Simian immunodeficiency virus lentivector corrects human X-linked chronic granulomatous disease in the NOD/SCID mouse xenograft

Y. Ikeda, N. Naumann, U. Choi, 2007, Gene Therapy.

Persistent Mycobacterium avium infection following nonmyeloablative allogeneic peripheral blood stem cell transplantation for interferon-gamma receptor-1 deficiency.

S. Holland, G. Uzel, H. Malech, 2003, Blood.

peripheral blood CD34+ cells 2m -/- repopulating mobilized human β oxidase defect in NOD/SCID/ levels of functional correction of the chronic granulomatous disease Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high

D. Bodine, H. Malech, E. Vanin, 2013 .

Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD34+ cells.

D. Bodine, H. Malech, E. Vanin, 2003, Blood.

Peripheral blood progenitors as a target for genetic correction of p47phox-deficient chronic granulomatous disease.

R. Mulligan, G. Linton, S. Sekhsaria, 1993, Proceedings of the National Academy of Sciences of the United States of America.

vivo retroviral gene therapy Correction of canine x-linked severe combined immunodeficiency by in

N. Naumann, P. Moore, P. Felsburg, 2013 .

Diprotin A infusion into nonobese diabetic/severe combined immunodeficiency mice markedly enhances engraftment of human mobilized CD34+ peripheral blood cells.

U. Choi, H. Malech, T. Kawai, 2007, Stem cells and development.

Efficient and durable gene marking of hematopoietic progenitor cells in nonhuman primates after nonablative conditioning.

R. Johnson, A. Farese, T. MacVittie, 1999, Blood.

CD34+ peripheral blood progenitors as a target for genetic correction of the two flavocytochrome b558 defective forms of chronic granulomatous disease

H. Malech, N. Whiting-Theobald, G. Linton, 1994 .

CXCR4‐Transgene Expression Significantly Improves Marrow Engraftment of Cultured Hematopoietic Stem Cells

U. Choi, H. Malech, P. Murphy, 2004, Stem cells.

Genetic correction of p67phox deficient chronic granulomatous disease using peripheral blood progenitor cells as a target for retrovirus mediated gene transfer.

H. Malech, N. Whiting-Theobald, G. Linton, 1997, Blood.

Genetic Correction of p 67 phox Deficient Chronic Granulomatous Disease Using Peripheral Blood Progenitor Cells as a Target for Retrovirus Mediated Gene Transfer

H. Malech, N. Whiting-Theobald, G. Linton, 1997 .

Enhanced function with decreased internalization of carboxy-terminus truncated CXCR4 responsible for WHIM syndrome.

U. Choi, H. Malech, P. Murphy, 2005, Experimental hematology.

WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus-truncated CXCR4.

N. Naumann, U. Choi, H. Malech, 2007, Blood.

Nuclear-localizing O6-benzylguanine-resistant GFP-MGMT fusion protein as a novel in vivo selection marker.

A. Pegg, U. Choi, H. Malech, 2004, Experimental hematology.

Treatment of chronic granulomatous disease with nonmyeloablative conditioning and a T-cell-depleted hematopoietic allograft.

S. Holland, A. Barrett, R. Childs, 2001, The New England journal of medicine.

Immunoregulatory disorders associated with hereditary angioedema. II. Serologic and cellular abnormalities.

G. Tsokos, M. Frank, J. Balow, 1986, The Journal of allergy and clinical immunology.

Correction of canine X-linked severe combined immunodeficiency by in vivo retroviral gene therapy.

N. Naumann, B. Hartnett, P. Moore, 2006, Blood.

Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils.

D. Kuhns, N. Theobald, U. Choi, 2010, Blood.

Analysis of Human Phagocyte Flavocytochrome b558 by Mass Spectrometry*

T. Angel, E. Dratz, A. Jesaitis, 2006, Journal of Biological Chemistry.

Analysis of Human Phagocyte Flavocytochrome b 558

T. Angel, E. Dratz, A. Jesaitis, 2006 .

Transgene-free iPSCs generated from small volume peripheral blood nonmobilized CD34+ cells.

T. Myers, N. Theobald, U. Choi, 2013, Blood.

CD 34 + Peripheral Blood Progenitors as a Target for Genetic Correction of the Two Flavocytochrome bSs 8 Defective Forms of Chronic Granulomatous Disease

Harry, John, Julie, 2000 .

A bicistronic retrovirus vector containing a picornavirus internal ribosome entry site allows for correction of X-linked CGD by selection for MDR1 expression.

M. Gottesman, Y. Sugimoto, H. Malech, 1996, Blood.

Evidence for the existence of a novel pregnancy-associated soluble variant of the vascular endothelial growth factor receptor, Flt-1.

D. Pappin, S. Kaufmann, D. Rahman, 1998, Molecular human reproduction.

Persistence of recipient plasma cells and anti‐donor isohaemagglutinins in patients with delayed donor erythropoiesis after major ABO incompatible non‐myeloablative haematopoietic cell transplantation

J. P. McCoy, R. Srinivasan, J. McCoy, 2005, British journal of haematology.

Treatment of infections in patients with X-linked chronic granulomatous disease (CGD) with gene therapy

N. Theobald, H. Malech, E. Kang, 2008 .

Treatment of Infections in Patients with X-Linked Chronic Granulomatous Disease (XCGD) with Gene Therapy.

N. Theobald, H. Malech, E. Kang, 2007 .

The Late Dividing Population of γ‐Retroviral Vector Transduced Human Mobilized Peripheral Blood Progenitor Cells Contributes Most to Gene‐Marked Cell Engraftment in Nonobese Diabetic/Severe Combined Immunodeficient Mice

H. Malech, N. Whiting-Theobald, M. Gentsch, 2007, Stem cells.

CD34+ peripheral blood progenitors as a target for genetic correction of the two flavocytochrome b558 defective forms of chronic granulomatous disease.

H. Malech, N. Whiting-Theobald, G. Linton, 1994, Blood.

Concentrated RD 114-pseudotyped MFGS-gp 91 phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD / SCID / 2-microglobulin / repopulating mobilized human peripheral blood CD 34 cells

D. Bodine, H. Malech, E. Vanin, 2003 .

PERSISTENT MYCOBACTERIUM AVIUM INFECTION FOLLOWING NON - MYELOABLATIVE ALLOGENEIC PERIPHERAL BLOOD STEM CELL TRANSPLANTATION FOR INTERFERON -

S. Holland, G. Uzel, H. Malech, 2003 .

Concentrated RD114-Pseudotyped MFGS-gp91 Vector Achieves High Levels of Functional Correction of the Chronic Granulomatous Disease Oxidase Defect in NOD/SCID/β2m-/- Repopulating Mobilized Human Peripheral Blood CD34 Cells Running head: RD114 MFGS-gp91 correction of X-CGD Scientific section heading:

D. Bodine, H. Malech, E. Vanin, 2003 .