Mario Perl

发表

The Pararectus Approach in Acetabular Surgery: Radiological and Clinical Outcome

P. Augat, L. Wenzel, C. von Rüden, 2019, Journal of orthopaedic trauma.

Pulmonary contusion causes impairment of macrophage and lymphocyte immune functions and increases mortality associated with a subsequent septic challenge*

L. Kinzl, A. Ayala, F. Gebhard, 2005, Critical care medicine.

Ethyl pyruvate ameliorates hepatic injury following blunt chest trauma and hemorrhagic shock by reducing local inflammation, NF-kappaB activation and HMGB1 release

I. Marzi, B. Relja, K. Mörs, 2018, PloS one.

Inflammatory alterations in a novel combination model of blunt chest trauma and hemorrhagic shock.

F. Gebhard, Sonja T Braumüller, Mario Perl, 2011, The Journal of trauma.

In vivo gene silencing (with siRNA) of pulmonary expression of MIP‐2 versus KC results in divergent effects on hemorrhage‐induced, neutrophil‐mediated septic acute lung injury

C. Chung, A. Ayala, Joanne L. Lomas-Neira, 2005, Journal of leukocyte biology.

Role of alveolar macrophage and migrating neutrophils in hemorrhage-induced priming for ALI subsequent to septic challenge.

C. Chung, A. Ayala, W. Biffl, 2006, American journal of physiology. Lung cellular and molecular physiology.

The molecular fingerprint of lung inflammation after blunt chest trauma

A. Chinnaiyan, P. Ward, S. Denk, 2015, European Journal of Medical Research.

Epithelial Cell Apoptosis and Neutrophil Recruitment in Acute Lung Injury—A Unifying Hypothesis? What We Have Learned from Small Interfering RNAs

C. Chung, A. Ayala, Joanne L. Lomas-Neira, 2008, Molecular medicine.

Blockade of apoptosis as a rational therapeutic strategy for the treatment of sepsis.

C. Chung, A. Ayala, Joanne L. Lomas-Neira, 2007, Novartis Foundation symposium.

The role and regulation of apoptosis in sepsis

Leslie Jones, C. Chung, A. Ayala, 2005, Journal of endotoxin research.

The influence of coagulation and inflammation research on the improvement of polytrauma care

M. Huber-Lang, F. Gebhard, Mario Perl, 2012, European Journal of Trauma and Emergency Surgery.

SILENCING OF FAS, FAS-ASSOCIATED VIA DEATH DOMAIN, OR CASPASE 3 DIFFERENTIALLY AFFECTS LUNG INFLAMMATION, APOPTOSIS, AND DEVELOPMENT OF TRAUMA-INDUCED SEPTIC ACUTE LUNG INJURY

S. Denk, M. Huber-Lang, Sascha Weber, 2013, Shock.

Hydrodynamic delivery of siRNA in a mouse model of sepsis.

C. Chung, A. Ayala, Joanne L. Lomas-Neira, 2008, Methods in molecular biology.

Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis.

W. Cioffi, C. Chung, A. Ayala, 2005, The American journal of pathology.

Propofol--sweet dreams, but not for everyone?

F. Gebhard, Mario Perl, S. Fulda, 2011, Critical care medicine.

Ethyl pyruvate reduces acute lung damage following trauma and hemorrhagic shock via inhibition of NF-κB and HMGB1.

I. Marzi, B. Relja, K. Mörs, 2017, Immunobiology.

Cathepsin D is released after severe tissue trauma in vivo and is capable of generating C5a in vitro.

S. Fulda, S. Denk, M. Huber-Lang, 2012, Molecular immunology.

Cystic fibrosis patients with and without central nervous system complications following lung transplantation

A. Arroliga, P. Stillwell, Mario Perl, 2000, Pediatric pulmonology.

ROLE OF ALVEOLAR MACROPHAGE & MIGRATING

C. Chung, A. Ayala, W. Biffl, 2005 .

Ethanol, ethyl and sodium pyruvate decrease the inflammatory responses of human lung epithelial cells via Akt and NF-κB in vitro but have a low impact on hepatocellular cells.

I. Marzi, E. Juengel, B. Relja, 2016, International journal of molecular medicine.

Pathogenesis of indirect (secondary) acute lung injury

C. Chung, A. Ayala, Joanne L. Lomas-Neira, 2011, Expert review of respiratory medicine.

BLUNT CHEST TRAUMA INDUCES DELAYED SPLENIC IMMUNOSUPPRESSION

L. Kinzl, F. Gebhard, Mario Perl, 2004, Shock.

Divergent Effects of Neutrophils on Fas-Induced Pulmonary Inflammation, Apoptosis, and Lung Damage

A. Ayala, Mario Perl, Bastian Bruns, 2017, Shock.

Blunt chest trauma induces mediator-dependent monocyte migration to the lung

F. Gebhard, Annette Palmer, Sonja T Braumüller, 2010, Critical care medicine.

Ethanol Decreases Inflammatory Response in Human Lung Epithelial Cells by Inhibiting the Canonical NF-kB-Pathway

I. Marzi, B. Relja, S. Kany, 2017, Cellular Physiology and Biochemistry.

Sera from severe trauma patients with pneumonia and without infectious complications have differential effects on neutrophil biology

I. Marzi, B. Relja, F. Hildebrand, 2016, BMC Pulmonary Medicine.

Biochemical characterization of individual injury pattern and injury severity.

L. Kinzl, F. Gebhard, A. Beck, 2003, Injury.

Beneficial versus detrimental effects of neutrophils are determined by the nature of the insult.

W. Cioffi, C. Chung, A. Ayala, 2007, Journal of the American College of Surgeons.

Role of Complement C5 in Experimental Blunt Chest Trauma-Induced Septic Acute Lung Injury (ALI)

M. Huber-Lang, F. Gebhard, M. Kalbitz, 2016, PloS one.

Functional immune monitoring in severely injured patients—A pilot study

R. Halbgebauer, M. Huber-Lang, E. Barth, 2020, Scandinavian journal of immunology.

Humans on Neutrophils during Septic Shock in Changes and Regulation of the C5a Receptor

P. Monk, M. Mihlan, J. V. Sarma, 2022 .

Therapeutic accessibility of caspase-mediated cell death as a key pathomechanism in indirect acute lung injury*

R. Thakkar, C. Chung, A. Ayala, 2010, Critical care medicine.

Acute Alcohol Binge Deteriorates Metabolic and Respiratory Compensation Capability After Blunt Chest Trauma Followed by Hemorrhagic Shock—A New Research Model

I. Marzi, B. Relja, K. Mörs, 2017, Alcoholism, clinical and experimental research.

Suppression of the interleukin-1β-induced inflammatory response of human Chang liver cells by acute and subacute exposure to alcohol: an in vitro study

I. Marzi, B. Relja, S. Kany, 2018, Croatian medical journal.

Pre- or post-treatment with ethanol and ethyl pyruvate results in distinct anti-inflammatory responses of human lung epithelial cells triggered by interleukin-6.

I. Marzi, B. Relja, Mario Perl, 2015, Molecular medicine reports.

THE ROLE OF C5A IN THE INNATE IMMUNE RESPONSE AFTER EXPERIMENTAL BLUNT CHEST TRAUMA

D. Rittirsch, M. Huber-Lang, C. Bartl, 2007, Shock.

Apoptosis in sepsis: mechanisms, clinical impact and potential therapeutic targets.

C. Chung, A. Ayala, Joanne L. Lomas-Neira, 2008, Current pharmaceutical design.

The pulmonary and hepatic immune microenvironment and its contribution to the early systemic inflammation following blunt chest trauma

L. Kinzl, F. Gebhard, Sonja T Braumüller, 2006, Critical care medicine.

Hypercapnic acidosis in acute lung injury: inevitable side effect or unexpected benefit?

P. Radermacher, M. Huber-Lang, Mario Perl, 2008, Critical care medicine.

Cardiopulmonary, Histological, and Inflammatory Alterations After Lung Contusion in a Novel Mouse Model of Blunt Chest Trauma

L. Kinzl, F. Gebhard, Mario Perl, 2003, Shock.

Role of Activated Neutrophils in Chest Trauma–Induced Septic Acute Lung Injury

S. Denk, M. Huber-Lang, A. Ayala, 2012, Shock.

The immune response after fracture trauma is different in old compared to young patients

M. Huber-Lang, A. Nüssler, M. van Griensven, 2014, Immunity & Ageing.

Inflammatory and apoptotic alterations in serum and injured tissue after experimental polytrauma in mice: Distinct early response compared with single trauma or “double-hit” injury

S. Denk, M. Huber-Lang, P. Stahel, 2013, The journal of trauma and acute care surgery.

A New Experimental Polytrauma Model in Rats: Molecular Characterization of the Early Inflammatory Response

M. Huber-Lang, A. Ignatius, P. Stahel, 2012, Mediators of inflammation.

Interleukin-6 (IL-6) – an Early Marker of Chest Trauma

L. Kinzl, G. Steinbach, F. Gebhard, 2002, European Journal of Trauma.

SHOCK AND HEMORRHAGE: AN OVERVIEW OF ANIMAL MODELS

Alfred Ayala, C. Chung, A. Ayala, 2005, Shock.

The Pattern of Preformed Cytokines in Tissues Frequently Affected by Blunt Trauma

L. Kinzl, M. Bachem, H. Gross, 2003, Shock.

EARLY EXPRESSION CHANGES OF COMPLEMENT REGULATORY PROTEINS AND C5a RECEPTOR (CD88) ON LEUKOCYTES AFTER MULTIPLE INJURY IN HUMANS

D. Rittirsch, M. Huber-Lang, F. Gebhard, 2010, Shock.

Alcohol Binge Reduces Systemic Leukocyte Activation and Pulmonary PMN Infiltration After Blunt Chest Trauma and Hemorrhagic Shock

I. Marzi, B. Relja, K. Mörs, 2018, Inflammation.

PULMONARY CONTUSION INDUCES ALVEOLAR TYPE 2 EPITHELIAL CELL APOPTOSIS: ROLE OF ALVEOLAR MACROPHAGES AND NEUTROPHILS

M. Huber-Lang, M. Bachem, Sonja T Braumüller, 2008, Shock.

Leukocyte apoptosis and its significance in sepsis and shock

C. Chung, A. Ayala, Joanne L. Lomas-Neira, 2005, Journal of leukocyte biology.

Contribution of anti-inflammatory/immune suppressive processes to the pathology of sepsis.

C. Chung, A. Ayala, Mario Perl, 2006, Frontiers in bioscience : a journal and virtual library.

Changes and Regulation of the C5a Receptor on Neutrophils during Septic Shock in Humans

P. Monk, M. Mihlan, J. V. Sarma, 2013, The Journal of Immunology.

Role of Programmed Cell Death in the Immunopathogenesis of Sepsis.

C. Chung, A. Ayala, Mario Perl, 2007, Drug discovery today. Disease mechanisms.

Case Report: Dysplasia Epiphysealis Hemimelica: A Case Report with Novel Pathophysiologic Aspects

R. Brenner, M. Nelitz, S. Lippacher, 2009, Clinical orthopaedics and related research.

Early Complementopathy After Multiple Injuries in Humans

A. Blom, D. Rittirsch, M. Huber-Lang, 2012, Shock.

Is the function of alveolar macrophages altered following blunt chest trauma?

M. Huber-Lang, F. Gebhard, Mario Perl, 2011, Langenbeck's Archives of Surgery.

Risk Factors for Failure in Conservatively Treated Osteoporotic Vertebral Fractures: A Systematic Review

G. Osterhoff, M. Scheyerer, M. Pumberger, 2021, Global spine journal.

The pararectus approach for internal fixation of acetabular fractures involving the anterior column: evaluating the functional outcome

P. Augat, V. Bühren, L. Wenzel, 2018, International Orthopaedics.

Divergent Effects of Activated Neutrophils on Inflammation, Kupffer Cell/Splenocyte Activation, and Lung Injury Following Blunt Chest Trauma

M. Huber-Lang, A. Ayala, M. Bachem, 2012, Shock.

Fas-induced pulmonary apoptosis and inflammation during indirect acute lung injury.

W. Cioffi, C. Chung, A. Ayala, 2007, American journal of respiratory and critical care medicine.

Complement Factor C5a Inhibits Apoptosis of Neutrophils—A Mechanism in Polytrauma?

M. Huber-Lang, F. Gebhard, Mario Perl, 2021, Journal of clinical medicine.

Apoptotic and inflammatory signaling via Fas and tumor necrosis factor receptor I contribute to the development of chest trauma-induced septic acute lung injury

T. Wirth, S. Denk, M. Huber-Lang, 2013, The journal of trauma and acute care surgery.

Die neuen Heilverfahren der DGUV: Aus Sicht der BG Kliniken

V. Bühren, Mario Perl, 2016, Der Unfallchirurg.

Contents Vol. 48, 2012

J. Lange, I. Mulder, N. Komen, 2012, European Surgical Research.

Polymicrobial sepsis enhances clearance of apoptotic immune cells by splenic macrophages.

W. Cioffi, C. Chung, A. Ayala, 2007, Surgery.

Granzyme B: a new crossroad of complement and apoptosis.

S. Denk, M. Huber-Lang, M. Kalbitz, 2012, Advances in experimental medicine and biology.

Induziert das stumpfe Thoraxtrauma eine Aktivierung zirkulierender Monozyten

F. Gebhard, L. Kinzl, Mario Perl, 2003 .

The Role and Source of Tumor Necrosis Factor-&agr; in Hemorrhage-Induced Priming for Septic Lung Injury

C. Chung, A. Ayala, Joanne L. Lomas-Neira, 2012, Shock.