I. Syk

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Lactobacillus plantarum 299v Does Not Reduce Enteric Bacteria or Bacterial Translocation in Patients Undergoing Colon Resection

P. Mangell, S. Ahrné, B. Jeppsson, 2012, Digestive Diseases and Sciences.

Influence of primary tumour and patient factors on survival in patients undergoing curative resection and treatment for liver metastases from colorectal cancer

E. Holmberg, P. Naredi, I. Syk, 2019, BJS open.

MiR-155-5p positively regulates CCL17-induced colon cancer cell migration by targeting RhoA

H. Thorlacius, I. Syk, A. Al-haidari, 2017, Oncotarget.

Impact of patient, primary tumor and metastatic pattern including tumor location on survival in patients undergoing ablation or resection for colorectal liver metastases: A population-based national cohort study.

E. Holmberg, P. Naredi, I. Syk, 2020, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

Optimal fractionation of preoperative radiotherapy and timing to surgery for rectal cancer (Stockholm III): a multicentre, randomised, non-blinded, phase 3, non-inferiority trial.

H. Johansson, B. Cedermark, B. Glimelius, 2017, The Lancet. Oncology.

Effect of More vs Less Frequent Follow-up Testing on Overall and Colorectal Cancer–Specific Mortality in Patients With Stage II or III Colorectal Cancer: The COLOFOL Randomized Clinical Trial

L. Påhlman, E. Horváth-Puhó, H. Sørensen, 2018, JAMA.

Risk of recurrence after endoscopic resection of nonpedunculated T1 colorectal cancer.

H. Thorlacius, I. Syk, V. Arthursson, 2022, Endoscopy.

Lymphovascular Infiltration, Not Depth of Invasion, is the Critical Risk Factor of Metastases in Early Colorectal Cancer

P. Krarup, E. Toth, H. Thorlacius, 2020, Annals of surgery.

Patterns and resectability of colorectal cancer recurrences: outcome study within the COLOFOL trial

S. Petersen, E. Holmberg, P. Naredi, 2021, BJS open.

Water soluble contrast enema examination of the integrity of the rectal anastomosis prior to loop ileostomy reversal may be superfluous

I. Syk, P. Buchwald, G. Lindmark, 2015, International Journal of Colorectal Disease.

Cytoreductive surgery and intraperitoneal chemotherapy versus systemic chemotherapy for colorectal peritoneal metastases: A randomised trial.

B. Glimelius, M. Torkzad, P. Cashin, 2016, European journal of cancer.

Survival after operations for ischaemic bowel disease.

S. Elmståhl, I. Syk, M. Wadman, 2000, The European journal of surgery = Acta chirurgica.

recruitment in septic lung injury formation in alveolar macrophages and neutrophil Geranylgeranyl transferase regulates CXC chemokine

B. Jeppsson, I. Syk, Z. Hasan, 2016 .

HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation.

H. Thorlacius, I. Syk, A. Al-haidari, 2014, Biochemical and biophysical research communications.

CCR4 mediates CCL17 (TARC)-induced migration of human colon cancer cells via RhoA/Rho-kinase signaling

K. Jirström, H. Thorlacius, I. Syk, 2013, International Journal of Colorectal Disease.

Delineating the intra-patient heterogeneity of molecular alterations in treatment-naïve colorectal cancer with peritoneal carcinomatosis

D. Gisselsson, K. Jirström, J. Eberhard, 2022, Modern Pathology.

Low‐dose aspirin use and colorectal cancer survival in 32,195 patients—A national cohort study

B. Glimelius, I. Syk, K. Ekström Smedby, 2022, Cancer medicine.

Standard protocol for assessment of colon cancer improves the quality of pathology

F. Olofsson, I. Syk, P. Buchwald, 2011, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation. Al-Haidari, Amr; Syk, Ingvar; Thorlacius, Henrik

H. Thorlacius, I. Syk, A. Al-haidari, 2014 .

Self-expanding metal stents in malignant colonic obstruction: experiences from Sweden

E. Toth, H. Thorlacius, A. Németh, 2011, BMC Research Notes.

GM6001 Increases Anastomotic Leakage following Colonic Obstruction Possibly by Impeding Epithelialization.

P. Krarup, J. Seidelin, M. Ågren, 2015, Surgical infections.

Epidemiology and Prognostic Factors in Acute Superior Mesenteric Artery Occlusion

S. Acosta, O. Ekberg, S. Elmståhl, 2010, Journal of Gastrointestinal Surgery.

Distinct patterns of leukocyte recruitment in the pulmonary microvasculature in response to local and systemic inflammation.

M. Menger, H. Thorlacius, J. Slotta, 2013, American journal of physiology. Lung cellular and molecular physiology.

Travel time to care does not affect survival for patients with colorectal cancer in northern Sweden: A data linkage study from the Risk North database

B. Melin, I. Syk, Gustav Silander, 2020, PloS one.

Peritoneal mesothelioma in Sweden: A population‐based study

P. Cashin, W. Graf, I. Syk, 2019, Cancer medicine.

Low molecular weight heparin started before surgery as prophylaxis against deep vein thrombosis: 2500 versus 5000 Xal units in 2070 patients

B. Risberg, D. Bergqvist, J. Frisell, 1995 .

Postoperative complications following colonic resection for cancer are associated with impaired long‐term survival

I. Syk, Ö. Arnarson, S. Butt-Tuna, 2019, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Wide excision in right-sided colon cancer is associated with decreased survival

F. Olofsson, S. Elmståhl, I. Syk, 2013, Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society.

Quality of life and cost effectiveness in a randomized trial of patients with colorectal cancer and peritoneal metastases.

B. Glimelius, P. Cashin, W. Graf, 2018, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

Postoperative fever, bowel ischaemia and cytokine response to abdominal aortic aneurysm repair--a comparison between endovascular and open surgery.

B. Lindblad, J. Brunkwall, B. Risberg, 1998, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

Experimental Colonic Obstruction Increases Collagen Degradation by Matrix Metalloproteinases in the Bowel Wall

U. Mirastschijski, B. Jeppsson, M. Ågren, 2003, Diseases of the colon and rectum.

Neutrophil‐derived matrix metalloproteinase‐9 is a potent activator of trypsinogen in acinar cells in acute pancreatitis

S. Regnér, B. Jeppsson, H. Thorlacius, 2012, Journal of leukocyte biology.

Rho-Kinase Signaling Regulates Pulmonary Infiltration of Neutrophils in Abdominal Sepsis Via Attenuation of CXC Chemokine Formation and Mac-1 Expression on Neutrophils

B. Jeppsson, H. Thorlacius, I. Syk, 2012, Shock.

Rac1‐dependent secretion of platelet‐derived CCL5 regulates neutrophil recruitment via activation of alveolar macrophages in septic lung injury

E. Zhang, H. Thorlacius, I. Syk, 2015, Journal of leukocyte biology.

Purification, localization, and expression of human intestinal alkaline sphingomyelinase Published, JLR Papers in Press, April 1, 2003. DOI 10.1194/jlr.M300037-JLR200

G. Hansen, A. Nilsson, H. Sjöström, 2003, Journal of Lipid Research.

Systemic Interleukin-6 Response to Colorectal Surgery Originates from the Bowel

A. Bjartell, P. Mangell, B. Jeppsson, 2002, Digestive Surgery.

Rapid morphological changes and loss of collagen following experimental acute colonic obstruction

P. Krarup, M. Ågren, I. Syk, 2013, International Journal of Colorectal Disease.

Compression anastomotic ring-locking procedure (CARP) is a safe and effective method for intestinal anastomoses following left-sided colonic resection

E. Toth, H. Thorlacius, I. Syk, 2015, International Journal of Colorectal Disease.

The Compression Anastomotic Ring-Locking Procedure: A Novel Technique for Creating a Sutureless Colonic Anastomosis

H. Thorlacius, I. Syk, D. Vilhjalmsson, 2014, European Surgical Research.

Outcomes of Simultaneous Resections and Classical Strategy for Synchronous Colorectal Liver Metastases in Sweden: A Nationwide Study with Special Reference to Major Liver Resections

B. Isaksson, A. Norén, C. Sturesson, 2020, World Journal of Surgery.

Liver-first strategy for synchronous colorectal liver metastases - an intention-to-treat analysis.

J. Nilsson, C. Sturesson, I. Syk, 2017, HPB : the official journal of the International Hepato Pancreato Biliary Association.

Action of matrix metalloproteinases at restricted sites in colon anastomosis repair: an immunohistochemical and biochemical study.

J. Lindebjerg, J. Delaissé, T. L. Andersen, 2006, Surgery.

Inhibition of matrix metalloproteinases enhances breaking strength of colonic anastomoses in an experimental model

B. Jeppsson, M. Ågren, I. Syk, 2001, The British journal of surgery.

Experimental evaluation of clinical colon anastomo- tic leakage

L. Jørgensen, N. Qvist, I. Syk, 2014 .

Proinflammatory role of neutrophil extracellular traps in abdominal sepsis.

E. Zhang, H. Thorlacius, I. Syk, 2014, American journal of physiology. Lung cellular and molecular physiology.

Impact of MDCT with intravenous contrast on the survival in patients with acute superior mesenteric artery occlusion

S. Acosta, O. Ekberg, S. Elmståhl, 2010, Emergency Radiology.

No benefit of extended mesenteric resection with central vascular ligation in right‐sided colon cancer

F. Olofsson, S. Elmståhl, I. Syk, 2016, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Podocalyxin-like protein expression in primary colorectal cancer and synchronous lymph node metastases

M. Uhlén, K. Jirström, J. Eberhard, 2013, Diagnostic Pathology.

Unspecific clinical presentation of bowel ischemia in the very old. Digitalis treatment - a reason for higher mortality?

S. Elmståhl, I. Syk, M. Wadman, 2004, Aging clinical and experimental research.

Simvastatin Protects Against T Cell Immune Dysfunction in Abdominal Sepsis

B. Jeppsson, H. Thorlacius, I. Syk, 2012, Shock.

Management of Aneurysm Sac Hygroma

L. Lönn, B. Risberg, I. Syk, 2004, Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists.

Collagen levels are normalized after decompression of experimentally obstructed colon

M. Ågren, I. Syk, M. Rehn, 2011, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

Cost comparisons of endoscopic and surgical resection of stage T1 rectal cancer

J. Norlin, E. Toth, H. Thorlacius, 2021, Endoscopy International Open.

Long-term survival after self-expanding metallic stent or stoma decompression as bridge to surgery in acute malignant large bowel obstruction

H. Thorlacius, I. Syk, M. Lepsenyi, 2021, BJS open.

Population‐based data from the Swedish Colon Cancer Registry

H. Olsson, L. Påhlman, B. Glimelius, 2013, The British journal of surgery.

CXCL2-CXCR2 axis mediates αV integrin-dependent peritoneal metastasis of colon cancer cells

H. Thorlacius, I. Syk, Milladur Rahman, 2021, Clinical & Experimental Metastasis.

MicroRNA-340-5p inhibits colon cancer cell migration via targeting of RhoA

H. Thorlacius, I. Syk, Milladur Rahman, 2020, Scientific Reports.

Abdominal plain film findings in acute ischemic bowel disease differ with age

O. Ekberg, S. Elmståhl, B. Elmståhl, 2006, Acta radiologica.

Metalloproteinases regulate CD40L shedding from platelets and pulmonary recruitment of neutrophils in abdominal sepsis

M. Menger, B. Jeppsson, H. Thorlacius, 2012, Inflammation Research.

Malignant fibrous histiocytoma of soft tissue. Correlation between clinical variables and histologic malignancy grade

A. Rydholm, I. Syk, Anders Rydholm, 1986, Cancer.

Platelet shedding of CD40L is regulated by matrix metalloproteinase‐9 in abdominal sepsis

B. Jeppsson, H. Thorlacius, I. Syk, 2013, Journal of thrombosis and haemostasis : JTH.

Rac1 signaling regulates sepsis-induced pathologic inflammation in the lung via attenuation of Mac-1 expression and CXC chemokine formation.

B. Jeppsson, H. Thorlacius, I. Syk, 2013, The Journal of surgical research.

Interventions to reduce dehydration related to defunctioning loop ileostomy after low anterior resection in rectal cancer: a prospective cohort study

K. Blomberg, I. Syk, P. Buchwald, 2020, ANZ journal of surgery.

No scientific base for more radical lymphadenectomy in colon cancer.

I. Syk, 2013, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

I. Syk, P. Buchwald, G. Lindmark, 2012, International Journal of Colorectal Disease.

Registries on peritoneal surface malignancies throughout the world, their use and their options

F. Jamali, B. Rau, S. O'dwyer, 2017, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

MiR-155-5p controls colon cancer cell migration via post-transcriptional regulation of Human Antigen R (HuR).

H. Thorlacius, I. Syk, A. Al-haidari, 2018, Cancer letters.

Who should operate patients presenting with emergent colon cancer? A comparison of short- and long-term outcome depending on surgical sub-specialization

I. Syk, S. Butt, Ö. Arnarson, 2023, World Journal of Emergency Surgery.

Rho Kinase Regulates Induction of T-Cell Immune Dysfunction in Abdominal Sepsis

B. Jeppsson, H. Thorlacius, I. Syk, 2013, Infection and Immunity.

Treatment and survival of patients with metachronous colorectal lung metastases

S. Petersen, E. Holmberg, P. Naredi, 2023, Journal of surgical oncology.

Disparities in colorectal cancer between Northern and SouthernSweden – a report from the new RISK North database

R. Henriksson, B. Melin, I. Syk, 2018, Acta oncologica.

Neutrophil extracellular traps promote peritoneal metastasis of colon cancer cells

H. Thorlacius, I. Syk, Milladur Rahman, 2019, Oncotarget.

Outcomes of liver-first strategy and classical strategy for synchronous colorectal liver metastases in Sweden.

B. Isaksson, A. Norén, C. Sturesson, 2018, HPB : the official journal of the International Hepato Pancreato Biliary Association.

Transanal formation of anastomosis using C-REX device is feasible and effective in high anterior resection

H. Thorlacius, I. Syk, M. Lepsenyi, 2023, International Journal of Colorectal Disease.

CRCBaSe: a Swedish register-based resource for colorectal adenocarcinoma research

B. Glimelius, K. E. Smedby, I. Syk, 2023, Acta oncologica.

Geranylgeranyl transferase regulates CXC chemokine formation in alveolar macrophages and neutrophil recruitment in septic lung injury.

B. Jeppsson, H. Thorlacius, I. Syk, 2013, American journal of physiology. Lung cellular and molecular physiology.

High Tie or not in Resection for Cancer in the Sigmoid Colon?

F. Olofsson, S. Elmståhl, I. Syk, 2018, Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society.

S100B profiles and cognitive function at high altitude.

E. Sigurdsson, T. Gudbjartsson, H. Bjursten, 2010, High altitude medicine & biology.

CALL FOR PAPERS Translational Research in Acute Lung Injury and Pulmonary Fibrosis Distinct patterns of leukocyte recruitment in the pulmonary microvasculature in response to local and systemic inflammation

M. Menger, H. Thorlacius, J. Slotta, 2013 .

The Delphi and GRADE methodology used in the PSOGI 2018 consensus statement on Pseudomyxoma Peritonei and Peritoneal Mesothelioma.

M. Simone, A. Nissan, J. Burger, 2019, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

Postoperative downregulation of MHC class II antigen on monocytes does not differ between open and endovascular repair of aortic aneurysms.

L. Truedsson, B. Risberg, I. Syk, 1999, The European journal of surgery = Acta chirurgica.

Abdominal Closure With Reinforcing Suture Decreases Incisional Hernia Incidence After CRS/HIPEC

O. Ekberg, I. Syk, U. Petersson, 2023, Journal of Abdominal Wall Surgery.

Metalloproteinases regulate CD40L shedding from platelets and pulmonary recruitment of neutrophils in abdominal sepsis

M. Menger, B. Jeppsson, H. Thorlacius, 2012, Inflammation Research.

Rac1‐dependent secretion of platelet‐derived CCL5 regulates neutrophil recruitment via activation of alveolar macrophages in septic lung injury

E. Zhang, H. Thorlacius, I. Syk, 2015, Journal of leukocyte biology.

Geranylgeranyl transferase regulates CXC chemokine formation in alveolar macrophages and neutrophil recruitment in septic lung injury.

B. Jeppsson, H. Thorlacius, I. Syk, 2013, American journal of physiology. Lung cellular and molecular physiology.

Rho-Kinase Signaling Regulates Pulmonary Infiltration of Neutrophils in Abdominal Sepsis Via Attenuation of CXC Chemokine Formation and Mac-1 Expression on Neutrophils

B. Jeppsson, H. Thorlacius, I. Syk, 2012, Shock.

S100B profiles and cognitive function at high altitude.

E. Sigurdsson, T. Gudbjartsson, H. Bjursten, 2010, High altitude medicine & biology.

The COLOFOL trial: study design and comparison of the study population with the source cancer population

E. Horváth-Puhó, H. Sørensen, S. Petersen, 2016, Clinical epidemiology.