A. Mizoguchi

发表

Current Understanding of Dysbiosis in Disease in Human and Animal Models

Atsushi Mizoguchi, Emiko Mizoguchi, E. Mizoguchi, 2016, Inflammatory bowel diseases.

Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria.

A. Kaser, L. Bry, J. Glickman, 2006, The Journal of clinical investigation.

Hepatic FcRn regulates albumin homeostasis and susceptibility to hepatotoxins

Inger, J. Andersen, S. D. Jones, 2018 .

Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice.

R. Xavier, D. Podolsky, E. Mizoguchi, 2002, Gastroenterology.

Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice.

F. Alt, C. Klein, S. Snapper, 2003, Blood.

Gene Therapy Gene Therapy for Wiskott Aldrich Syndrome-Rescue of T-Cell Signaling and Amelioration of Colitis upon Transplantation of Retrovirally Transduced Hematopoietic Stem Cells in Mice

F. Alt, C. Klein, S. Snapper, 2002 .

Protein Kinase C θ Plays a Fundamental Role in Different Types of Chronic Colitis

Y. Shimomura, A. Mizoguchi, Kiyotaka Nagahama, 2008 .

The critical role of interleukin 4 but not interferon gamma in the pathogenesis of colitis in T-cell receptor alpha mutant mice.

E. Mizoguchi, A. Bhan, A. Mizoguchi, 1999, Gastroenterology.

IBD: Pathogenesis

A. Toubert, P. Cattan, J. Panés, 2009, Mucosal Immunology.

Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum

N. Salzman, A. Biswas, Yuen-Joyce Liu, 2010, Proceedings of the National Academy of Sciences.

High Endogenous Expression of Chitinase 3-Like 1 and Excessive Epithelial Proliferation with Colonic Tumor Formation in MOLF/EiJ Mice

M. Mino‐Kenudson, E. Mizoguchi, Arianna K. DeGruttola, 2015, PloS one.

Intestinal heat shock protein 110 regulates expression of CD1d on intestinal epithelial cells.

R. Sartor, S. Colgan, L. Mayer, 2003, The Journal of clinical investigation.

Lymphocyte-dependent and Th2 cytokine-associated colitis in mice deficient in Wiskott-Aldrich syndrome protein.

C. Klein, S. Snapper, D. Nguyen, 2007, Gastroenterology.

Chitinase 3-like-1 expression in colonic epithelial cells as a potentially novel marker for colitis-associated neoplasia.

M. Mino‐Kenudson, M. Bissonnette, V. Lladó, 2011, The American journal of pathology.

Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation.

R. Blumberg, E. Mizoguchi, A. Bhan, 2002, Immunity.

Epithelial Control of Gut-Associated Lymphoid Tissue Formation through p38α-Dependent Restraint of NF-κB Signaling

M. Karin, Y. Sano, M. Choo, 2016, The Journal of Immunology.

Inducible IL-12-producing B cells regulate Th2-mediated intestinal inflammation.

Y. Shimomura, A. Bhan, A. Mizoguchi, 2007, Gastroenterology.

Chitin microparticles for the control of intestinal inflammation

V. Lladó, Zongxi Li, Y. Shibata, 2012, Inflammatory bowel diseases.

Limited CD4 T-cell diversity associated with colitis in T-cell receptor alpha mutant mice requires a T helper 2 environment.

R. Blumberg, E. Mizoguchi, A. Bhan, 2000, Gastroenterology.

Examination of the role of galectins in intestinal inflammation.

A. Nishida, A. Mizoguchi, C. Lau, 2015, Methods in molecular biology.

Regulatory B cells in mouse models of intestinal inflammation.

A. Nishida, E. Mizoguchi, A. Mizoguchi, 2014, Methods in molecular biology.

Chitinase 3-like 1 Synergistically Activates IL6-mediated STAT3 Phosphorylation in Intestinal Epithelial Cells in Murine Models of Infectious Colitis

J. Elias, H. Shi, E. Mizoguchi, 2014, Inflammatory bowel diseases.

Ectopic Epithelial Deaminase in IBD

A. Mizoguchi, 2013 .

Immunobiology of B Cells in Inflammatory Bowel Disease

A. Bhan, A. Mizoguchi, 2012 .

Bone marrow stromal cell transplants prevent experimental enterocolitis and require host CD11b+ splenocytes.

R. Weissleder, Y. Iwamoto, Joshua Dunham, 2011, Gastroenterology.

Regulatory role of B-1 B cells in chronic colitis.

Y. Benno, Y. Shimomura, E. Mizoguchi, 2008, International immunology.

A Case for Regulatory B Cells1

A. Bhan, A. Mizoguchi, 2006, The Journal of Immunology.

The Transcription Factor T-bet Regulates Mucosal T Cell Activation in Experimental Colitis and Crohn's Disease

S. Szabo, M. Neurath, P. Galle, 2002, The Journal of experimental medicine.

Regulation of human intestinal intraepithelial lymphocyte cytolytic function by biliary glycoprotein (CD66a).

G. Freeman, R. Blumberg, N. Utku, 1999, Journal of immunology.

Anti-KCA-3, a monoclonal antibody reactive with a rat complement C3 receptor, distinguishes Kupffer cells from other macrophages.

N. Narula, H. Rabb, M. Arnaout, 1993, Journal of immunology.

The herbal medicine sho-saiko-to inhibits proliferation of cancer cell lines by inducing apoptosis and arrest at the G0/G1 phase.

M. Kojiro, K. Fukuda, H. Yano, 1994, Cancer research.

A Case for Regulatory B Cells

A. Bhan, A. Mizoguchi, 2005 .

Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice.

T. Hibi, M. Suematsu, K. Matsushima, 2008, Gastroenterology.

Role of cytokines in the early stages of chronic colitis in TCR alpha-mutant mice.

E. Mizoguchi, A. Bhan, A. Mizoguchi, 1997, Laboratory investigation; a journal of technical methods and pathology.

Suppressive Role of B Cells in Chronic Colitis of T Cell Receptor α Mutant Mice

F. Preffer, R. N. Smith, E. Mizoguchi, 1997, The Journal of experimental medicine.

In vivo generation of oligoclonal colitic CD4+ T-cell lines expressing a distinct T-cell receptor Vbeta.

W. Faubion, S. Rietdijk, A. Bhan, 2005, Gastroenterology.

Cytokine imbalance and autoantibody production in T cell receptor-alpha mutant mice with inflammatory bowel disease

S. Tonegawa, E. Mizoguchi, A. Bhan, 1996, The Journal of experimental medicine.

Regulatory role of mature B cells in a murine model of inflammatory bowel disease.

F. Preffer, E. Mizoguchi, A. Bhan, 2000, International immunology.

Healing of intestinal inflammation by IL‐22

A. Mizoguchi, 2012, Inflammatory bowel diseases.

Role of the CD5 molecule on TCR γδ T cell‐mediated immune functions: development of germinal centers and chronic intestinal inflammation

F. Preffer, E. Mizoguchi, A. Bhan, 2003 .

Colitis in transgenic and knockout animals as models of human inflammatory bowel disease

R. N. Smith, A. Bhan, A. Mizoguchi, 1999, Immunological reviews.

Regulatory role of mature B cells in a murine model of inflammatory bowel disease

F. Preffer, E. Mizoguchi, A. Bhan, 2000 .

Lessons for human inflammatory bowel disease from experimental models.

R. N. Smith, E. Mizoguchi, A. Bhan, 1999, Current opinion in gastroenterology.

Suppressive Role of B Cells in Chronic Colitis of T Cell Receptor (cid:97) Mutant Mice

F. Preffer, R. N. Smith, E. Mizoguchi, 1997 .

Role of the CD5 molecule on TCR gammadelta T cell-mediated immune functions: development of germinal centers and chronic intestinal inflammation.

F. Preffer, E. Mizoguchi, A. Bhan, 2003, International immunology.

Essential role for Vav 1 in activation , but not development , of gd T cells

R. Xavier, F. Alt, W. Swat, 2003 .

Altered serum profile of the interleukin-22 system in inflammatory bowel disease.

K. Mitsuyama, H. Yamasaki, T. Torimura, 2020, Cytokine.

Mice with a Selective Deletion of the CC Chemokine Receptors 5 or 2 Are Protected from Dextran Sodium Sulfate-Mediated Colitis: Lack of CC Chemokine Receptor 5 Expression Results in a NK1.1+ Lymphocyte-Associated Th2-Type Immune Response in the Intestine1

Atsushi Mizoguchi, Emiko Mizoguchi, Daniel K. Podolsky, 2000, The Journal of Immunology.

Animal models of inflammatory bowel disease.

A. Mizoguchi, 2012, Progress in molecular biology and translational science.

Is the sugar always sweet in intestinal inflammation?

E. Mizoguchi, A. Mizoguchi, 2007, Immunologic research.

Establishment of two distinct human hepatocellular carcinoma cell lines from a single nodule showing clonal dedifferentiation of cancer cells

M. Kojiro, H. Yano, A. Mizoguchi, 1993, Hepatology.

Inflammatory bowel disease, past, present and future: lessons from animal models

E. Mizoguchi, A. Mizoguchi, 2008, Journal of Gastroenterology.

Insights from Recent Advances in Animal Models of Inflammatory Bowel Disease

E. Mizoguchi, A. Bhan, A. Mizoguchi, 2013 .

Establishment and characterization of a new human extrahepatic bile duct carcinoma cell line (KMBC)

M. Kojiro, H. Yano, A. Mizoguchi, 1992, Cancer.

The membrane-bound mucin Muc1 regulates T helper 17-cell responses and colitis in mice.

A. Andoh, A. Nishida, H. Shi, 2012, Gastroenterology.

Crohn disease: A current perspective on genetics, autophagy and immunity

J. Rioux, R. Xavier, M. Parkes, 2011, Autophagy.

Animal models of IBD: linkage to human disease.

E. Mizoguchi, A. Mizoguchi, 2010, Current opinion in pharmacology.

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis.

R. Xavier, A. Andoh, R. Blumberg, 2008, The Journal of clinical investigation.

Genetically engineered mouse models for studying inflammatory bowel disease

E. Mizoguchi, Hidetomo Himuro, Toshiyuki Okada, 2016, The Journal of pathology.

A unique B2 B cell subset in the intestine

S. Pillai, Y. Shimomura, H. Shi, 2008, The Journal of experimental medicine.

Animal Models of Inflammatory Bowel Disease for Drug Discovery

A. Andoh, A. Mizoguchi, 2013 .

Mechanistic roles of epithelial and immune cell signaling during the development of colitis-associated cancer.

E. Mizoguchi, R. Subramaniam, A. Mizoguchi, 2016, Cancer research frontiers.

DNA methylation in inflammatory bowel disease and beyond.

E. Mizoguchi, Daren Low, A. Mizoguchi, 2013, World journal of gastroenterology.

Immune Networks in Animal Models of Inflammatory Bowel Disease

E. Mizoguchi, A. Bhan, A. Mizoguchi, 2003, Inflammatory bowel diseases.

Role of appendix in the development of inflammatory bowel disease in TCR-alpha mutant mice

E. Mizoguchi, A. Bhan, A. Mizoguchi, 1996, The Journal of experimental medicine.

Colonic epithelial functional phenotype varies with type and phase of experimental colitis.

R. Xavier, D. Podolsky, E. Mizoguchi, 2003, Gastroenterology.

Long Acellular Nerve Transplants for Allogeneic Grafting and the Effects of Basic Fibroblast Growth Factor on the Growth of Regenerating Axons in Dogs: A Preliminary Report

K. Tohyama, T. Morihara, M. Shirasu, 1998, Experimental Neurology.

Mice with a selective deletion of the chemokine receptors CCR5 or CCR2 are protected from DSS-mediated colitis: Lack of ccr5 expression results in TH2 type immune response in the intestine

R. Macdermott, N. Maeda, D. Podolsky, 2000 .

Differential requirement for CARMA1 in agonist‐selected T‐cell development

R. Xavier, B. Medoff, A. Luster, 2009, European journal of immunology.

Alteration of a polyclonal to an oligoclonal immune response to cecal aerobic bacterial antigens in TCR alpha mutant mice with inflammatory bowel disease.

S. Tonegawa, E. Mizoguchi, A. Bhan, 1996, International immunology.

Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury

J. Andersen, S. D. Jones, N. Kaplowitz, 2017, Proceedings of the National Academy of Sciences.

Chitinase 3-like 1 induces survival and proliferation of intestinal epithelial cells during chronic inflammation and colitis-associated cancer by regulating S100A9

Li Lin, M. Mino‐Kenudson, Aylwin Ng, 2015, Oncotarget.

A Review of Selected IBD Biomarkers: From Animal Models to Bedside

E. Mizoguchi, R. Subramaniam, Toshiyuki Okada, 2021, Diagnostics.

TNF receptor type I-dependent activation of innate responses to reduce intestinal damage-associated mortality.

D. Podolsky, E. Mizoguchi, A. Mizoguchi, 2008, Gastroenterology.

Clinical importance of IL-22 cascade in IBD

E. Mizoguchi, Hidetomo Himuro, A. Mizoguchi, 2017, Journal of Gastroenterology.

Spontaneous Chronic Colitis in TCRα-Mutant Mice; an Experimental Model of Human Ulcerative Colitis

E. Mizoguchi, A. Bhan, A. Mizoguchi, 2000, International reviews of immunology.

Potential Novel Marker of Malignant Disease

M. Yokoyama, A. Yamada, Y. Imai, 2007 .

Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells.

D. Roopenian, W. Lencer, R. Blumberg, 2004, Immunity.

Paradoxical roles of different nitric oxide synthase isoforms in colonic injury.

R. Xavier, H. Mashimo, D. Podolsky, 2004, American journal of physiology. Gastrointestinal and liver physiology.

A novel intestinal organoid-based in vitro co-culture system to dissect out the initial host defense system

A. Mizoguchi, 2016, Journal of Gastroenterology.

Roles of galectins in inflammatory bowel disease.

A. Hokama, E. Mizoguchi, A. Mizoguchi, 2008, World journal of gastroenterology.

Induced reactivity of intestinal CD4(+) T cells with an epithelial cell lectin, galectin-4, contributes to exacerbation of intestinal inflammation.

S. Snapper, R. Blumberg, A. Hokama, 2004, Immunity.

Tuning of Protein Kinase Circuitry by p38α Is Vital for Epithelial Tissue Homeostasis*

K. Otsu, Y. Sano, H. Sakurai, 2013, The Journal of Biological Chemistry.

Inducible colitis-associated glycome capable of stimulating the proliferation of memory CD4+ T cells

H. Ikeuchi, T. Hibi, F. Preffer, 2012, The Journal of experimental medicine.

Dependence of intestinal granuloma formation on unique myeloid DC-like cells.

R. Blumberg, Y. Shimomura, E. Mizoguchi, 2007, The Journal of clinical investigation.

A cholangiocellular carcinoma nude mouse strain showing histologic alteration from adenocarcinoma to squamous cell carcinoma

M. Kojiro, H. Yano, A. Mizoguchi, 1992, Cancer.

Essential role for Vav1 in activation, but not development, of γδ T cells

R. Xavier, F. Alt, W. Swat, 2003 .

Diversity and shared T-cell receptor repertoire analysis in esophageal squamous cell carcinoma

T. Sudo, Y. Akagi, N. Mori, 2021, Oncology Letters.

Antineutrophil cytoplasmic antibodies in T-cell receptor alpha-deficient mice with chronic colitis.

E. Mizoguchi, A. Bhan, J. Niles, 1997, Gastroenterology.

Toll-like receptor 4-mediated regulation of spontaneous Helicobacter-dependent colitis in IL-10-deficient mice.

S. Snapper, K. Haigis, D. Nguyen, 2009, Gastroenterology.

Suppressive Role of B Cells in Chronic Colitis of T Cell Receptor α Mutant Mice

F. Preffer, R. N. Smith, E. Mizoguchi, 1997, The Journal of experimental medicine.

Interleukin‐10‐producing B‐cells in autoimmune bullous diseases

T. Hashimoto, A. Mizoguchi, 2017, The British journal of dermatology.

The Transcription Factor T-bet Regulates Mucosal T Cell Activation in Experimental Colitis and Crohn's Disease

S. Szabo, M. Neurath, L. Glimcher, 2002, The Journal of experimental medicine.

Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice.

F. Alt, C. Klein, S. Snapper, 2003, Blood.

New models of chronic intestinal inflammation

E. Mizoguchi, A. Bhan, A. Mizoguchi, 1994 .

Suppressive Role of B Cells in Chronic Colitis of T Cell Receptor (cid:97) Mutant Mice

E. Mizoguchi, A. Bhan, A. Mizoguchi, 1997 .

The Transcription Factor T-bet Regulates Mucosal T Cell Activation in Experimental Colitis and Crohn's Disease

S. Szabo, M. Neurath, L. Glimcher, 2002, The Journal of experimental medicine.

Establishment of two distinct human hepatocellular carcinoma cell lines from a single nodule showing clonal dedifferentiation of cancer cells

M. Kojiro, H. Yano, A. Mizoguchi, 1993, Hepatology.

Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice.

F. Alt, C. Klein, S. Snapper, 2003, Blood.

Chitinase 3-like 1 Synergistically Activates IL6-mediated STAT3 Phosphorylation in Intestinal Epithelial Cells in Murine Models of Infectious Colitis

J. Elias, H. Shi, E. Mizoguchi, 2014, Inflammatory bowel diseases.

TNF receptor type I-dependent activation of innate responses to reduce intestinal damage-associated mortality.

D. Podolsky, E. Mizoguchi, A. Mizoguchi, 2008, Gastroenterology.

Recently Updated Role of Chitinase 3-like 1 on Various Cell Types as a Major Influencer of Chronic Inflammation

A. Mizoguchi, Takayuki Sadanaga, Emiko Mizoguchi, 2024, Cells.