S. Vreugde

发表

Low pH nasal rinse solution enhances mupirocin antimicrobial efficacy

C. Cooksley, K. Hon, S. Liu, 2022, Rhinology journal.

The international sinonasal microbiome study (ISMS): a multi-centre, multi-national collaboration characterising the microbial ecology of the sinonasal cavity

Matthew R. Dillon, Emily K. Cope, J. Caporaso, 2019, bioRxiv.

The international sinonasal microbiome study (ISMS): a multi-centre, international characterization of sinonasal bacterial ecology

Matthew R. Dillon, Emily K. Cope, J. Caporaso, 2019 .

USH3A transcripts encode clarin-1, a four-transmembrane-domain protein with a possible role in sensory synapses

Tsviya Olender, Doron Lancet, Shmuel Pietrokovski, 2002, European Journal of Human Genetics.

Efficacy and Safety of Novel Beta-Chitin Patches as Haemostat in Rat Vascular and Neurosurgical Model

C. J. McAdam, J. Finnie, P. Wormald, 2022, Frontiers in Surgery.

Association of intracellular Staphylococcus aureus with prognosis in chronic rhinosinusitis

P. Wormald, S. Vreugde, A. Psaltis, 2016, International forum of allergy & rhinology.

An in vivo safety and efficacy demonstration of a topical liposomal nitric oxide donor treatment for Staphylococcus aureus biofilm-associated rhinosinusitis.

C. Prestidge, B. Thierry, Shasha Rao, 2015, Translational research : the journal of laboratory and clinical medicine.

Role of fungi in chronic rhinosinusitis through ITS sequencing

P. Wormald, S. Vreugde, A. Psaltis, 2018, The Laryngoscope.

Staphylococcus aureus biofilm activates the nucleotide‐binding oligomerization domain containing 2 (Nod2) pathway and proinflammatory factors on a human sinonasal explant model

C. Cooksley, P. Wormald, S. Vreugde, 2013, International forum of allergy & rhinology.

Efficacy of anti-biofilm gel, chitogel-mupirocin-budesonide in a sheep sinusitis model

S. Moratti, P. Wormald, S. Vreugde, 2020 .

Clinical characterization of genetic hearing loss caused by a mutation in the POU4F3 transcription factor.

K. Avraham, M. Frydman, S. Vreugde, 2000, Archives of otolaryngology--head & neck surgery.

The clinical outcomes of medical therapies in chronic rhinosinusitis is independent of microbiomic outcomes: a double-blinded, randomised placebo-controlled trial.

C. Cooksley, P. Wormald, S. Vreugde, 2020, Rhinology.

Sirtuin‐1 Controls Poly (I:C)‐Dependent Matrix Metalloproteinase 9 Activation in Primary Human Nasal Epithelial Cells

A. Homma, C. Cooksley, P. Wormald, 2018, American journal of respiratory cell and molecular biology.

Pseudomonas aeruginosa Exoprotein-Induced Barrier Disruption Correlates With Elastase Activity and Marks Chronic Rhinosinusitis Severity

C. Cooksley, P. Wormald, Jian Li, 2019, Front. Cell. Infect. Microbiol..

Identification of the Bacterial Reservoirs for the Middle Ear Using Phylogenic Analysis

P. Wormald, S. Vreugde, A. Psaltis, 2017, JAMA otolaryngology-- head & neck surgery.

3D bioprinting of a cell-laden antibacterial polysaccharide hydrogel composite.

D. Losic, T. Tung, A. Mazinani, 2021, Carbohydrate polymers.

TLR Signals in Epithelial Cells in the Nasal Cavity and Paranasal Sinuses

A. Homma, C. Cooksley, Y. Nakamaru, 2021, Frontiers in Allergy.

Cousins, siblings, or copies: the genomics of recurrent Staphylococcus aureus infections in chronic rhinosinusitis

P. Speck, P. Wormald, S. Vreugde, 2014, International forum of allergy & rhinology.

Preclinical Development of a Bacteriophage Cocktail for Treating Multidrug Resistant Pseudomonas aeruginosa Infections

P. Wormald, K. Hon, S. Vreugde, 2021, Microorganisms.

Alloiococcus otitidis Forms Multispecies Biofilm with Haemophilus influenzae: Effects on Antibiotic Susceptibility and Growth in Adverse Conditions

Katharina Richter, P. Wormald, S. Vreugde, 2017, Front. Cell. Infect. Microbiol..

Safety evaluation of a sinus surfactant in an explant‐based cytotoxicity assay

C. Cooksley, P. Wormald, S. Vreugde, 2014, The Laryngoscope.

Comparative antibacterial activity of 2D materials coated on porous-titania.

D. Losic, T. Tung, M. J. Nine, 2021, Journal of materials chemistry. B.

Proteomic analysis of nasal mucus samples of healthy patients and patients with chronic rhinosinusitis

J. Finnie, P. Wormald, S. Vreugde, 2021 .

Increased IL-13 expression is independently associated with neo-osteogenesis in patients with chronic rhinosinusitis.

C. Cooksley, P. Wormald, S. Vreugde, 2017, The Journal of allergy and clinical immunology.

Chronic Rhinosinusitis, S. aureus Biofilm and Secreted Products, Inflammatory Responses, and Disease Severity

Gohar Shaghayegh, C. Cooksley, P. Wormald, 2022, Biomedicines.

Naive and Effector B-cell Subtypes are Increased in Chronic Rhinosinusitis with Polyps

P. Wormald, S. Vreugde, A. Psaltis, 2018, American journal of rhinology & allergy.

Green synthesized colloidal silver is devoid of toxic effects on primary human nasal epithelial cells in vitro.

Gohar Shaghayegh, C. Cooksley, P. Wormald, 2021, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Scoping review of chronic rhinosinusitis proteomics.

P. Wormald, S. Vreugde, A. Psaltis, 2020, Rhinology.

Role of intracellular zinc in molecular and cellular function in allergic inflammatory diseases.

S. Hatakeyama, A. Homma, Y. Nakamaru, 2020, Allergology international : official journal of the Japanese Society of Allergology.

Microbiotyping the Sinonasal Microbiome

Matthew R. Dillon, Emily K. Cope, J. Caporaso, 2019, bioRxiv.

Association between Group 2 Innate Lymphoid Cells enrichment, nasal polyps and allergy in Chronic Rhinosinusitis

E. Hauben, C. Cooksley, P. Wormald, 2014, Allergy.

Staphylococcus aureus impairs the airway epithelial barrier in vitro

P. Wormald, E. Roscioli, S. Vreugde, 2015, International forum of allergy & rhinology.

Deferiprone and Gallium-Protoporphyrin Have the Capacity to Potentiate the Activity of Antibiotics in Staphylococcus aureus Small Colony Variants

T. Coenye, C. Prestidge, Katharina Richter, 2017, Front. Cell. Infect. Microbiol..

The effect of neutrophil serine proteases on human nasal epithelial cell barrier function

P. Wormald, S. Vreugde, A. Psaltis, 2019, International forum of allergy & rhinology.

Staphylococcus Aureus Biofilms Induce Apoptosis and Expression of Interferon-γ, Interleukin-10, and Interleukin-17A on Human Sinonasal Explants

C. Cooksley, P. Wormald, E. Roscioli, 2015, American journal of rhinology & allergy.

The Bacterial Microbiome in Chronic Rhinosinusitis: Richness, Diversity, Postoperative Changes, and Patient Outcomes

P. Wormald, S. Vreugde, A. Bassiouni, 2016, American journal of rhinology & allergy.

Trimellitic anhydride facilitates transepithelial permeability disrupting tight junctions in sinonasal epithelial cells.

S. Fujieda, C. Cooksley, P. Wormald, 2021, Toxicology letters.

Small‐colony variants and phenotype switching of intracellular Staphylococcus aureus in chronic rhinosinusitis

C. Cooksley, P. Wormald, E. Roscioli, 2014, Allergy.

Association between mucosal barrier disruption by Pseudomonas aeruginosa exoproteins and asthma in patients with chronic rhinosinusitis

C. Cooksley, P. Wormald, S. Vreugde, 2021, Allergy.

Gene expression differences in nitric oxide and reactive oxygen species regulation point to an altered innate immune response in chronic rhinosinusitis

P. Wormald, S. Vreugde, L. Tan, 2013, International forum of allergy & rhinology.

The presence of virus significantly associates with chronic rhinosinusitis disease severity

S. Bialasiewicz, P. Wormald, S. Vreugde, 2019, Allergy.

Chronic Rhinosinusitis with Polyps Is Characterized by Increased Mucosal and Blood Th17 Effector Cytokine Producing Cells

P. Wormald, S. Vreugde, A. Psaltis, 2017, Front. Physiol..

Safety and Efficacy of Topical Chitogel- Deferiprone-Gallium Protoporphyrin in Sheep Model

C. Prestidge, Katharina Richter, S. Moratti, 2018, Front. Microbiol..

Long-Term Safety of Topical Bacteriophage Application to the Frontal Sinus Region

P. Speck, P. Wormald, Jason R. Clark, 2017, Front. Cell. Infect. Microbiol..

Inhibition of Staphylococcus aureus and Pseudomonas aeruginosa biofilms by quatsomes in low concentrations

C. Prestidge, B. Thierry, P. Wormald, 2020, Experimental biology and medicine.

Innate lymphoid type 2 cells in chronic rhinosinusitis

P. Wormald, S. Vreugde, 2016, Current opinion in allergy and clinical immunology.

T regulatory and Th17 cells in chronic rhinosinusitis with polyps

P. Wormald, S. Vreugde, A. Psaltis, 2016, International forum of allergy & rhinology.

APTC-C-SA01: A Novel Bacteriophage Cocktail Targeting Staphylococcus aureus and MRSA Biofilms

K. Shearwin, P. Wormald, K. Hon, 2022, International journal of molecular sciences.

Safety and efficacy of a bacteriophage cocktail in an in vivo model of Pseudomonas aeruginosa sinusitis

J. Finnie, S. Morales, P. Wormald, 2019, Translational research : the journal of laboratory and clinical medicine.

Staphylococcus aureus Lipoteichoic Acid has a Dual Effect on Inflammatory Responses in Airway Epithelial Cells via the Transcription Factor NFκB

C. Cooksley, S. Lester, P. Wormald, 2020 .

Der p 1 Disrupts the Epithelial Barrier and Induces IL-6 Production in Patients With House Dust Mite Allergic Rhinitis

S. Fujieda, P. Wormald, K. Ogi, 2021, Frontiers in Allergy.

Mucosal zinc deficiency in chronic rhinosinusitis with nasal polyposis contributes to barrier disruption and decreases ZO‐1

P. Wormald, E. Roscioli, S. Vreugde, 2018, Allergy.

Role of crushed skeletal muscle extract in hemostasis

P. Wormald, S. Vreugde, A. Bassiouni, 2015, International forum of allergy & rhinology.

The prevalence and expression of inherited connexin 26 mutations associated with nonsyndromic hearing loss in the Israeli population

K. Avraham, M. Frydman, A. Orr-Urtreger, 1999, Human Genetics.

Th17 Cytokines Disrupt the Airway Mucosal Barrier in Chronic Rhinosinusitis

P. Wormald, S. Vreugde, M. Ramezanpour, 2016, Mediators of inflammation.

Sub-Inhibitory Clindamycin and Azithromycin reduce S. aureus Exoprotein Induced Toxicity, Inflammation, Barrier Disruption and Invasion

P. Wormald, S. Vreugde, A. Psaltis, 2019, Journal of clinical medicine.

Tertiary lymphoid organs in recalcitrant chronic rhinosinusitis.

S. McColl, S. Lester, P. Wormald, 2017, The Journal of allergy and clinical immunology.

Characterization of human nasal organoids from chronic rhinosinusitis patients

Gohar Shaghayegh, P. Wormald, K. Hon, 2022, Biology open.

Kappa‐carrageenan sinus rinses reduce inflammation and intracellular Staphylococcus aureus infection in airway epithelial cells

C. Cooksley, S. Vreugde, A. Psaltis, 2019, International forum of allergy & rhinology.

Primary human nasal epithelial cells: a source of poly (I:C) LMW-induced IL-6 production

P. Wormald, S. Vreugde, A. Psaltis, 2018, Scientific Reports.

In vitro safety evaluation of human nasal epithelial cell monolayers exposed to carrageenan sinus wash

S. Vreugde, A. Psaltis, M. Ramezanpour, 2017, International forum of allergy & rhinology.

The microbiome of otitis media with effusion

P. Wormald, S. Vreugde, A. Psaltis, 2016, The Laryngoscope.

TLR response pathways in NuLi-1 cells and primary human nasal epithelial cells.

C. Cooksley, P. Wormald, E. Roscioli, 2015, Molecular immunology.

Colloidal silver combating pathogenic Pseudomonas aeruginosa and MRSA in chronic rhinosinusitis.

T. Coenye, C. Prestidge, C. Cooksley, 2021, Colloids and surfaces. B, Biointerfaces.

Barrier disruptive effects of mucus isolated from chronic rhinosinusitis patients

J. Finnie, P. Wormald, S. Vreugde, 2020, Allergy.

Chitogel following endoscopic sinus surgery promotes a healthy microbiome and reduces postoperative infections

P. Wormald, S. Vreugde, E. Vyskocil, 2022, International forum of allergy & rhinology.

Manuka honey sinus irrigations in recalcitrant chronic rhinosinusitis: phase 1 randomized, single‐blinded, placebo‐controlled trial

E. Ooi, P. Wormald, S. Vreugde, 2019, International forum of allergy & rhinology.

The persistence of intracellular Staphylococcus aureus in the sinuses: a longitudinal study.

P. Wormald, S. Vreugde, A. Psaltis, 2017, Rhinology.

The fungal microbiome in chronic rhinosinusitis: richness, diversity, postoperative changes and patient outcomes

S. Dowd, P. Wormald, S. Vreugde, 2014, International forum of allergy & rhinology.

Intracellular Staphylococcus aureus: the Trojan horse of recalcitrant chronic rhinosinusitis?

R. Douglas, P. Wormald, S. Vreugde, 2013, International forum of allergy & rhinology.

Inflammasome gene expression alterations in Staphylococcus aureus biofilm-associated chronic rhinosinusitis.

P. Zalewski, P. Wormald, M. Rischmueller, 2013, Rhinology.

In vitro characteristics of an airway barrier‐disrupting factor secreted by Staphylococcus aureus

P. Wormald, E. Roscioli, S. Vreugde, 2018, International forum of allergy & rhinology.

Zinc-depletion associates with tissue eosinophilia and collagen depletion in chronic rhinosinusitis.

A. Homma, C. Cooksley, P. Wormald, 2020, Rhinology.

Association between viral infection and increased mucosal eosinophils and CD8+CD103+ T cells in chronic rhinosinusitis

S. Bialasiewicz, P. Wormald, S. Vreugde, 2020, International forum of allergy & rhinology.

Corynebacterium accolens inhibits Staphylococcus aureus induced mucosal barrier disruption

P. Wormald, Yulin Zhao, K. Hon, 2022, Frontiers in Microbiology.

Antibiotics Affect ROS Production and Fibroblast Migration in an In-vitro Model of Sinonasal Wound Healing

P. Wormald, S. Vreugde, A. Psaltis, 2020, Frontiers in Cellular and Infection Microbiology.

Metallothionein-3 is a clinical biomarker for tissue zinc levels in nasal mucosa.

A. Homma, C. Cooksley, P. Wormald, 2021, Auris, nasus, larynx.

Nano-hemostats and a Pilot Study of Their Use in a Large Animal Model of Major Vessel Hemorrhage in Endoscopic Skull Base Surgery

S. Vreugde, A. Psaltis, A. Jukes, 2016, Journal of Neurological Surgery Part B: Skull Base.

Overcoming bacteriophage insensitivity in Staphylococcus aureus using clindamycin and azithromycinat subinhibitory concentrations

K. Shearwin, J. Finnie, S. Morales, 2021, Allergy.

Safety and Tolerability of Bacteriophage Therapy for Chronic Rhinosinusitis Due to Staphylococcus aureus.

S. Morales, P. Wormald, S. Vreugde, 2019, JAMA otolaryngology-- head & neck surgery.

Early and late complications of endoscopic hemostatic techniques following different carotid artery injury characteristics

P. Wormald, S. Vreugde, Sathish Paramasivan, 2014, International forum of allergy & rhinology.

Deferiprone has anti-inflammatory properties and reduces fibroblast migration in vitro

P. Wormald, S. Vreugde, A. Psaltis, 2019, Scientific Reports.

Effect of commercial nasal steroid preparation on bacterial growth

Katharina Richter, C. Cooksley, P. Wormald, 2019, International forum of allergy & rhinology.

Corticosteroids directly reduce Staphylococcus aureus biofilm growth: An in vitro study

P. Wormald, S. Vreugde, C. Jardeleza, 2014, The Laryngoscope.

In vitro safety evaluation of a povidone‐iodine solution applied to human nasal epithelial cells

P. Wormald, S. Vreugde, A. Psaltis, 2020, International forum of allergy & rhinology.

Bacteriophage effectively kills multidrug resistant Staphylococcus aureus clinical isolates from chronic rhinosinusitis patients

Katharina Richter, S. Morales, P. Wormald, 2018, International forum of allergy & rhinology.

[Alloiococcus otitidis forms multispecies biofilm with Haemophilus influenzae: effects on antibiotic susceptibility and growth in adverse conditions].

Katharina Richter, P. Wormald, S. Vreugde, 2018, Vestnik otorinolaringologii.

Extent of maxillary sinus surgery and its effect on instrument access, irrigation penetration, and disease clearance

P. Wormald, S. Vreugde, A. Psaltis, 2019, International forum of allergy & rhinology.

Silver nanoparticles as a bioadjuvant of antibiotics against biofilm-mediated infections with methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa in chronic rhinosinusitis patients.

C. Cooksley, P. Wormald, S. Vreugde, 2021, Pathology.

Fighting sinus‐derived Staphylococcus aureus biofilms in vitro with a bacteriophage‐derived muralytic enzyme

C. Cooksley, P. Wormald, S. Vreugde, 2016, International forum of allergy & rhinology.

Mind “De GaPP”: in vitro efficacy of deferiprone and gallium‐protoporphyrin against Staphylococcus aureus biofilms

C. Prestidge, Katharina Richter, P. Wormald, 2016, International forum of allergy & rhinology.

Converging 2D Nanomaterials and 3D Bioprinting Technology: State‐of‐the‐Art, Challenges, and Potential Outlook in Biomedical Applications

Pei Lay Yap, D. Losic, T. Tung, 2021, Advanced healthcare materials.

The effect of chemical and structural modifiers on the haemostatic process and cytotoxicity of the beta-chitin patch

C. J. McAdam, L. Hanton, P. Wormald, 2021, Scientific Reports.

Topical colloidal silver as an anti‐biofilm agent in a Staphylococcus aureus chronic rhinosinusitis sheep model

P. Wormald, S. Vreugde, A. Bassiouni, 2015, International forum of allergy & rhinology.

Colloidal silver: a novel treatment for Staphylococcus aureus biofilms?

P. Wormald, S. Vreugde, C. Jardeleza, 2014, International forum of allergy & rhinology.

Staphylococcus Aureus V8 protease disrupts the integrity of the airway epithelial barrier and impairs IL‐6 production in vitro

G. Dubin, P. Wormald, S. Vreugde, 2018, The Laryngoscope.

SPPL2a and SPPL2b promote intramembrane proteolysis of TNFα in activated dendritic cells to trigger IL-12 production

E. Hauben, B. Martoglio, S. Lichtenthaler, 2006, Nature Cell Biology.

The international sinonasal microbiome study: A multicentre, multinational characterization of sinonasal bacterial ecology

Matthew R. Dillon, Emily K. Cope, J. Caporaso, 2020, Allergy.

Activity of Bacteriophages in Removing Biofilms of Pseudomonas aeruginosa Isolates from Chronic Rhinosinusitis Patients

W. Fokkens, S. Morales, B. Woodworth, 2017, Front. Cell. Infect. Microbiol..

Reduced Innate Immune Response to a Staphylococcus aureus Small Colony Variant Compared to Its Wild-Type Parent Strain

S. Kidd, C. Cooksley, P. Wormald, 2016, Front. Cell. Infect. Microbiol..

The potential of chitosan-based haemostats for use in neurosurgical setting – Literature review

P. Wormald, S. Vreugde, A. Sabab, 2021, Journal of Clinical Neuroscience.

Topical Colloidal Silver for the Treatment of Recalcitrant Chronic Rhinosinusitis

Katharina Richter, P. Wormald, S. Vreugde, 2018, Front. Microbiol..

Methylglyoxal‐augmented manuka honey as a topical anti–Staphylococcus aureus biofilm agent: safety and efficacy in an in vivo model

P. Wormald, S. Vreugde, Sathish Paramasivan, 2014, International forum of allergy & rhinology.

Distribution and Inhibition of Liposomes on Staphylococcus aureus and Pseudomonas aeruginosa Biofilm

C. Prestidge, B. Thierry, P. Wormald, 2015, PloS one.

From flies' eyes to our ears: Mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30

T. Walsh, M. King, Ming K. Lee, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Functional mgrA Influences Genetic Changes within a Staphylococcus aureus Cell Population over Time

A. Mira, A. Horswill, M. Carda-Diéguez, 2022, Journal of bacteriology.

High frequency of the deafness-associated 167delT mutation in the connexin 26 (GJB2) gene in Israeli Ashkenazim.

B. Bonné-Tamir, K. Avraham, A. Berry, 1999, American journal of medical genetics.

Wound healing in endoscopic sinus surgery: Phase 1 clinical trial evaluating the role of Chitogel with adjuvants

C. Cooksley, P. Wormald, S. Vreugde, 2022, Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery.

Prevention of peridural adhesions in spinal surgery: Assessing safety and efficacy of Chitogel with Deferiprone in a sheep model

Katharina Richter, S. Moratti, S. Otto, 2020, Journal of Clinical Neuroscience.

Fluticasone Propionate Suppresses Poly(I:C)-Induced ACE2 in Primary Human Nasal Epithelial Cells

S. Hatakeyama, T. Kondo, A. Homma, 2021, Frontiers in Cellular and Infection Microbiology.

Safety and efficacy of topical bacteriophage and ethylenediaminetetraacetic acid treatment of Staphylococcus aureus infection in a sheep model of sinusitis

P. Speck, S. Morales, P. Wormald, 2014, International forum of allergy & rhinology.

A human nasal explant model to study Staphylococcus aureus biofilm in vitro

C. Cooksley, P. Wormald, S. Vreugde, 2013, International forum of allergy & rhinology.

Effect of breathing profiles on nebuliser drug delivery targeting the paranasal sinuses in a post-operative nasal cavity

D. Fletcher, K. Inthavong, Y. Shang, 2021, Journal of Aerosol Science.

Numerical and Machine Learning Analysis of the Parameters Affecting the Regionally Delivered Nasal Dose of Nano- and Micro-Sized Aerosolized Drugs

M. Menden, O. Schmid, O. Pourmehran, 2023, Pharmaceuticals.

Acoustic drug delivery to the maxillary sinus.

B. Cazzolato, M. Arjomandi, O. Pourmehran, 2021, International journal of pharmaceutics.

Beethoven, a mouse model for dominant, progressive hearing loss DFNA36

H. Fuchs, K. Steel, R. Balling, 2002, Nature Genetics.

Prophages encoding human immune evasion cluster genes are enriched in Staphylococcus aureus isolated from chronic rhinosinusitis patients with nasal polyps

K. Shearwin, Gohar Shaghayegh, P. Wormald, 2021, Microbial genomics.

Calcific tendinitis of the longus colli muscle: Case report

Steven Laureys, D. Sartoris, M. Osteaux, 1997, Head & neck.

The global transcriptomic signature in sinonasal tissues reveals roles for tissue type and chronic rhinosinusitis disease phenotype.

A. Tsykin, A. Schreiber, J. Geoghegan, 2020, Rhinology.

Spontaneous Regression of Swollen Submandibular Glands in IgG4-Related Disease

A. Homma, Y. Nakamaru, S. Vreugde, 2019, Allergy & rhinology.

A Novel Rat Model to Test Intra-Abdominal Anti-adhesive Therapy

J. Finnie, P. Wormald, S. Vreugde, 2020, Frontiers in Surgery.

APTC-EC-2A: A Lytic Phage Targeting Multidrug Resistant E. coli Planktonic Cells and Biofilms

P. Wormald, K. Hon, S. Vreugde, 2022, Microorganisms.

The Microbiome of the Nasolacrimal System and Its Role in Nasolacrimal Duct Obstruction

P. Wormald, D. Selva, S. Vreugde, 2019, Ophthalmic plastic and reconstructive surgery.

Sinonasal Microbiome Sampling: A Comparison of Techniques

P. Wormald, S. Vreugde, A. Psaltis, 2015, PloS one.

Bacteriophage Reduces Biofilm of Staphylococcus Aureus Ex Vivo Isolates from Chronic Rhinosinusitis Patients

P. Speck, S. Morales, P. Wormald, 2014, American journal of rhinology & allergy.

Prevention of adhesions post-abdominal surgery: Assessing the safety and efficacy of Chitogel with Deferiprone in a rat model

G. Maddern, S. Moratti, J. Finnie, 2021, PloS one.

A Topical Hydrogel with Deferiprone and Gallium-Protoporphyrin Targets Bacterial Iron Metabolism and Has Antibiofilm Activity

T. Coenye, C. Prestidge, Katharina Richter, 2017, Antimicrobial Agents and Chemotherapy.

Quatsomes for the treatment of Staphylococcus aureus biofilm.

C. Prestidge, Katharina Richter, B. Thierry, 2015, Journal of materials chemistry. B.

Liposome-Encapsulated ISMN: A Novel Nitric Oxide-Based Therapeutic Agent against Staphylococcus aureus Biofilms

C. Prestidge, B. Thierry, Shasha Rao, 2014, PloS one.

Proteomic analysis of nasal mucus samples of healthy and chronic rhinosinusitis patients.

J. Finnie, P. Wormald, S. Vreugde, 2020, The Journal of allergy and clinical immunology.

Metastasis of a renal cell carcinoma to the nose and paranasal sinuses.

S. Vreugde, A. Halama, P. Deron, 1999, Acta oto-rhino-laryngologica Belgica.

In vitro safety and anti‐bacterial efficacy assessment of acriflavine

C. Cooksley, N. Singh, P. Wormald, 2022, Allergy. European Journal of Allergy and Clinical Immunology.

Primary human nasal epithelial cells: a source of poly (I:C) LMW-induced IL-6 production

P. Wormald, S. Vreugde, A. Psaltis, 2018, Scientific Reports.

Staphylococcus aureus biofilm secreted factors cause mucosal damage, mast cell infiltration and goblet cell hyperplasia in a rat rhinosinusitis model

Gohar Shaghayegh, P. Wormald, S. Vreugde, 2023, bioRxiv.

Chronic rhinosinusitis patients display an aberrant immune cell localisation with enhanced S. aureus biofilm metabolic activity and biomass

Gohar Shaghayegh, C. Cooksley, P. Wormald, 2022, Journal of Allergy and Clinical Immunology.

Staphylococcus aureus biofilm exoproteins are cytotoxic to human nasal epithelial barrier in chronic rhinosinusitis

C. Cooksley, P. Wormald, S. Vreugde, 2020, International forum of allergy & rhinology.

Prophage acquisition by Staphylococcus aureus contributes to the expansion of Staphylococcal immune evasion

K. Shearwin, Gohar Shaghayegh, P. Wormald, 2023, bioRxiv.

The intra-host evolutionary landscape and pathoadaptation of persistent Staphylococcus aureus in chronic rhinosinusitis

Gohar Shaghayegh, C. Cooksley, P. Wormald, 2023, bioRxiv.

Staphylococcal protein A modulates inflammation by inducing interferon signaling in human nasal epithelial cells

P. Wormald, K. Hon, S. Vreugde, 2022, Inflammation Research.

Cytokine-Induced Modulation of SARS-CoV2 Receptor Expression in Primary Human Nasal Epithelial Cells

P. Wormald, K. Hon, S. Vreugde, 2021, Pathogens.

Increased Serum IgG4 Associates with Asthma and Tissue Eosinophilia in Chronic Rhinosinusitis Patients

S. Lester, P. Wormald, M. Rischmueller, 2020, Pathogens.

Subepithelial inflammatory load and basement membrane thickening in refractory chronic rhinosinusitis with nasal polyposis: a histopathological study

P. Wormald, S. Vreugde, A. Bassiouni, 2016, International forum of allergy & rhinology.

In vitro and in vivo evaluation of probiotic properties of Corynebacterium accolens isolated from the human nasal cavity.

C. Cooksley, P. Wormald, S. Vreugde, 2021, Microbiological research.

The bacteriology of diabetic foot ulcers and infections and incidence of Staphylococcus aureus Small Colony Variants.

A. Mira, M. Carda-Diéguez, S. Kidd, 2023, Journal of medical microbiology.

Taking the Silver Bullet Colloidal Silver Particles for the Topical Treatment of Biofilm-Related Infections.

T. Coenye, C. Prestidge, Katharina Richter, 2017, ACS applied materials & interfaces.

Deferiprone has anti-inflammatory properties and reduces fibroblast migration in vitro

P. Wormald, S. Vreugde, A. Psaltis, 2019, Scientific Reports.

Prevention of false positive binding during immunofluorescence of Staphylococcus aureus infected tissue biopsies.

P. Wormald, E. Roscioli, H. Tran, 2012, Journal of immunological methods.

Tertiary Lymphoid Organs: A Primer for Otolaryngologists

P. Wormald, S. Vreugde, A. Psaltis, 2020, The Laryngoscope.

Identifying Intracellular Staphylococcus Aureus in Chronic Rhinosinusitis: A Direct Comparison of Techniques

P. Wormald, H. Tran, S. Vreugde, 2012, American journal of rhinology & allergy.

Proteomic characterisation of perhexiline treatment on THP-1 M1 macrophage differentiation

P. Drew, S. Vreugde, M. Ramezanpour, 2023, Frontiers in Immunology.

Nuclear myosin VI enhances RNA polymerase II-dependent transcription.

E. Hauben, S. Biffo, C. Ferrai, 2006, Molecular cell.

Comparative Viral Sampling in the Sinonasal Passages; Different Viruses at Different Sites

S. Bialasiewicz, P. Wormald, S. Vreugde, 2018, Front. Cell. Infect. Microbiol..

Staphylococcus aureus from patients with chronic rhinosinusitis show minimal genetic association between polyp and non-polyp phenotypes

D. Sarovich, E. Price, P. Wormald, 2018, BMC Ear, Nose and Throat Disorders.

Advancements in Acoustic Drug Delivery for Paranasal Sinuses: A Comprehensive Review.

O. Pourmehran, P. Wormald, J. Pourchez, 2023, International journal of pharmaceutics.

Probiotic manipulation of the chronic rhinosinusitis microbiome

P. Wormald, Peter-John Wormald, S. Vreugde, 2014, International forum of allergy & rhinology.

Haemostatic efficacy and inflammatory response of a novel beta-chitin patch in a cerebral small vessel injury model – A pilot study

P. Wormald, J. Manavis, S. Vreugde, 2023, Journal of Clinical Neuroscience.

Staphylococcus aureus biofilm properties and chronic rhinosinusitis severity scores correlate positively with total CD4+ T‐cell frequencies and inversely with its Th1, Th17 and regulatory cell frequencies

Gohar Shaghayegh, C. Cooksley, P. Wormald, 2023, Immunology.

Discordant frequencies of tissue‐resident and circulating CD180‐negative B cells in chronic rhinosinusitis

E. Hauben, P. Wormald, S. Vreugde, 2017, International forum of allergy & rhinology.

Colloidal silver against macrophage infections and biofilms of atypical mycobacteria

C. Cooksley, P. Wormald, S. Vreugde, 2023, BioMetals.

Deferiprone-gallium-protoporphyrin (IX): A promising treatment modality against Mycobacterium abscessus.

C. Cooksley, P. Wormald, S. Vreugde, 2023, Tuberculosis.

Haemostatic efficacy and inflammatory response of a novel beta-chitin patch in a cerebral small vessel injury model – A pilot study

P. Wormald, J. Manavis, S. Vreugde, 2023, Journal of Clinical Neuroscience.

Optimising Aerosol Delivery for Maxillary Sinus Deposition in a Post-FESS Sinonasal Cavities

K. Inthavong, Y. Shang, A. Rezk, 2021, Aerosol and Air Quality Research.

Pharokka: a fast scalable bacteriophage annotation tool

P. Wormald, S. Vreugde, A. Psaltis, 2022, Bioinform..

Corynebacterium accolens Has Antimicrobial Activity against Staphylococcus aureus and Methicillin-Resistant S. aureus Pathogens Isolated from the Sinonasal Niche of Chronic Rhinosinusitis Patients

C. Cooksley, P. Wormald, S. Vreugde, 2021, Pathogens.

Inducing a Mucosal Barrier–Sparing Inflammatory Response in Laboratory‐Grown Primary Human Nasal Epithelial Cells

P. Wormald, S. Vreugde, A. Psaltis, 2019, Current Protocols in Toxicology.

The effect of topical treatments for CRS on the sinonasal epithelial barrier.

J. L. Smith, S. Vreugde, M. Ramezanpour, 2017, Rhinology.

Plassembler: an automated bacterial plasmid assembly tool

A. Sheppard, S. Vreugde, V. Mallawaarachchi, 2023, Bioinformatics.

Optimal primer selection for sinus microbiome profiling: A comparative analysis of the V1‐V3 and V3‐4 16S target regions

P. Wormald, S. Vreugde, A. Psaltis, 2021, International forum of allergy & rhinology.

Identification of consensus head and neck cancer-associated microbiota signatures: a meta-analysis of 16S rRNA and The Cancer Microbiome Atlas datasets.

P. Wormald, S. Vreugde, A. Psaltis, 2023, medRxiv.

Fighting sinus‐derived Staphylococcus aureus biofilms in vitro with a bacteriophage‐derived muralytic enzyme

C. Cooksley, P. Wormald, S. Vreugde, 2016, International forum of allergy & rhinology.

S. aureus biofilm metabolic activity correlates positively with patients' eosinophil frequencies and disease severity in chronic rhinosinusitis.

Gohar Shaghayegh, C. Cooksley, P. Wormald, 2023, Microbes and infection.

The international sinonasal microbiome study (ISMS): a multi- 1 centre, international characterization of sinonasal bacterial ecology 2

Matthew R. Dillon, J. Caporaso, A. Shiffer, 2019 .

A Topical Hydrogel with Deferiprone and Gallium-Protoporphyrin Targets Bacterial Iron Metabolism and Has Antibiofilm Activity

T. Coenye, C. Prestidge, P. Wormald, 2017, Antimicrobial Agents and Chemotherapy.

Innate lymphoid type 2 cells in chronic rhinosinusitis

P. Wormald, S. Vreugde, 2016, Current opinion in allergy and clinical immunology.

How low can you go? Short-read polishing of Oxford Nanopore bacterial genome assemblies

R. Wick, T. Stinear, S. Vreugde, 2024, bioRxiv.

1S. aureus biofilm properties correlate with immune B cell subset frequencies and severity of chronic rhinosinusitis.

Gohar Shaghayegh, C. Cooksley, P. Wormald, 2024, Clinical immunology.

Early and late complications of endoscopic hemostatic techniques following different carotid artery injury characteristics

P. Wormald, S. Vreugde, Sathish Paramasivan, 2014, International forum of allergy & rhinology.

Deferiprone and Gallium-Protoporphyrin Chitogel as an antimicrobial treatment: Preclinical studies demonstrating antimicrobial activity for S. aureus infected cutaneous wounds.

Z. Kopecki, S. Vreugde, H. Haidari, 2024, International journal of biological macromolecules.

Identification of consensus head and neck cancer-associated microbiota signatures: a systematic review and meta-analysis of 16S rRNA and The Cancer Microbiome Atlas datasets.

P. Wormald, S. Vreugde, A. Psaltis, 2024, Journal of medical microbiology.

Staphylococcus aureus Biofilm-Secreted Factors Cause Mucosal Damage, Mast Cell Infiltration, and Goblet Cell Hyperplasia in a Rat Rhinosinusitis Model

Gohar Shaghayegh, P. Wormald, S. Vreugde, 2024, International journal of molecular sciences.

Nano-hemostats and a Pilot Study of Their Use in a Large Animal Model of Major Vessel Hemorrhage in Endoscopic Skull Base Surgery

P. Wormald, S. Vreugde, A. Psaltis, 2016, Journal of Neurological Surgery Part B: Skull Base.