Chongren Tang

发表

Oxidation of apolipoprotein A-I by myeloperoxidase impairs the initial interactions with ABCA1 required for signaling and cholesterol export1

J. Heinecke, J. Oram, Baohai Shao, 2010, Journal of Lipid Research.

Exosome-mediated transfer of anti-miR-33a-5p from transduced endothelial cells enhances macrophage and vascular smooth muscle cell cholesterol efflux.

D. Dichek, Lucia Vojtech, Chongren Tang, 2019, Human gene therapy.

High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis

B. Gillespie, S. Pennathur, J. Heinecke, 2013, Annals of the rheumatic diseases.

The Apolipoprotein-AI Mimetic Peptide L4F at a Modest Dose Does Not Attenuate Weight Gain, Inflammation, or Atherosclerosis in LDLR-Null Mice

S. Subramanian, A. Chait, G. Getz, 2014, PloS one.

Neutrophil Extracellular Trap–Derived Enzymes Oxidize High‐Density Lipoprotein: An Additional Proatherogenic Mechanism in Systemic Lupus Erythematosus

B. Gillespie, P. Thompson, J. Knight, 2014, Arthritis & rheumatology.

Hematopoietic ABCA1 deletion promotes monocytosis and worsens diet-induced insulin resistance in mice

Yuhua Liu, R. Leboeuf, J. Heinecke, 2016, Journal of Lipid Research.

ABCA1 Overexpression in Endothelial Cells In Vitro Enhances ApoAI-Mediated Cholesterol Efflux and Decreases Inflammation.

D. Dichek, F. Kim, Nagadhara Dronadula, 2019, Human gene therapy.

Both STAT3 activation and cholesterol efflux contribute to the anti-inflammatory effect of apoA-I/ABCA1 interaction in macrophages

R. Leboeuf, Chongren Tang, C. Storey, 2016, Journal of Lipid Research.

Obesity and weight loss result in increased adipose tissue ABCG1 expression in db/db mice.

R. Leboeuf, N. Pamir, J. Oram, 2012, Biochimica et biophysica acta.

Humans With Atherosclerosis Have Impaired ABCA1 Cholesterol Efflux and Enhanced High-Density Lipoprotein Oxidation by Myeloperoxidase

N. Brot, Abhishek Sinha, J. Heinecke, 2014, Circulation research.

An Amphipathic Helical Region of the N-terminal Barrel of Phospholipid Transfer Protein Is Critical for ABCA1-dependent Cholesterol Efflux*

J. Albers, J. Oram, W. Davidson, 2008, Journal of Biological Chemistry.

Phospholipid Transfer Protein Interacts with and Stabilizes ATP-binding Cassette Transporter A1 and Enhances Cholesterol Efflux from Cells*

A. Vaughan, J. Albers, J. Oram, 2003, Journal of Biological Chemistry.

Apolipoprotein AI and High-Density Lipoprotein Have Anti-Inflammatory Effects on Adipocytes via Cholesterol Transporters: ATP-Binding Cassette A-1, ATP-Binding Cassette G-1, and Scavenger Receptor B-1

S. Subramanian, A. Chait, E. Kim, 2013, Circulation research.

Cell lipid metabolism modulators 2-bromopalmitate, D609, monensin, U18666A and probucol shift discoidal HDL formation to the smaller-sized particles: implications for the mechanism of HDL assembly.

D. Rader, J. Millar, M. Phillips, 2016, Biochimica et biophysica acta.

Advanced glycation end product precursors impair ABCA1-dependent cholesterol removal from cells.

T. McDonald, R. Gerrity, J. Heinecke, 2005, Diabetes.

Glycation of HDL blunts its anti-inflammatory and cholesterol efflux capacities in vitro, but has no effect in poorly controlled type 1 diabetes subjects.

S. Subramanian, A. Chait, Baohai Shao, 2020, Journal of diabetes and its complications.

Apolipoprotein A-I and HDL Have Anti-Inflammatory Effects on Adipocytes via Cholesterol Transporters: ATP-Binding Cassette (ABC) A-1, ABCG-1 and Scavenger Receptor B-1(SRB-1)

S. Subramanian, A. Chait, L. Goodspeed, 2013 .

Sexually Dimorphic Relationships Among Saa3 (Serum Amyloid A3), Inflammation, and Cholesterol Metabolism Modulate Atherosclerosis in Mice

A. Chait, A. Lusis, S. Gharib, 2021, Arteriosclerosis, thrombosis, and vascular biology.

Helper-dependent adenoviral vectors are superior in vitro to first-generation vectors for endothelial cell-targeted gene therapy.

D. Dichek, F. Kim, Chongren Tang, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

ABCA1 is an extracellular phospholipid translocase

W. S. Davidson, J. Segrest, S. Aller, 2022, Nature Communications.

10,12-Conjugated linoleic acid supplementation improves HDL composition and function in mice

T. Vaisar, Chongren Tang, M. Omer, 2022, Journal of lipid research.

Apolipoprotein A-I Attenuates Palmitate-Mediated NF-κB Activation by Reducing Toll-Like Receptor-4 Recruitment into Lipid Rafts

A. Chait, F. Kim, J. Oram, 2012, PloS one.

Conformational flexibility of apolipoprotein A-I amino- and carboxy-termini is necessary for lipid binding but not cholesterol efflux

W. S. Davidson, K. Bornfeldt, Amy Shah, 2022, Journal of lipid research.

ABCA1 mutants reveal an interdependency between lipid export function, apoA-I binding activity, and Janus kinase 2 activation ** This work was supported by National Institutes of Health Grant RO1HL-55362. Published, JLR Papers in Press, September 5, 2008.

A. Vaughan, J. Oram, Chongren Tang, 2009, Journal of Lipid Research.

Janus kinase 2 modulates the lipid-removing but not protein-stabilizing interactions of amphipathic helices with ABCA1 Published, JLR Papers in Press, October 6, 2005.

A. Vaughan, G. Anantharamaiah, J. Oram, 2006, Journal of Lipid Research.

Janus Kinase 2 Modulates the Apolipoprotein Interactions with ABCA1 Required for Removing Cellular Cholesterol*

A. Vaughan, J. Oram, Chongren Tang, 2004, Journal of Biological Chemistry.

The Macrophage Cholesterol Exporter ABCA1 Functions as an Anti-inflammatory Receptor*

A. Vaughan, Yuhua Liu, P. Kessler, 2009, The Journal of Biological Chemistry.

Serum amyloid A impairs the antiinflammatory properties of HDL.

S. Subramanian, A. Chait, K. Elkon, 2016, The Journal of clinical investigation.

Serum amyloid A impairs the antiinflammatory properties of HDL.

S. Subramanian, A. Chait, K. Elkon, 2016, The Journal of clinical investigation.

Regulation of human delta-6 desaturase gene transcription: identification of a functional direct repeat-1 element.

Manabu T. Nakamura, S. Clarke, Chongren Tang, 2003, Journal of lipid research.

The E-box like sterol regulatory element mediates the suppression of human Delta-6 desaturase gene by highly unsaturated fatty acids.

Manabu T. Nakamura, S. Clarke, Chongren Tang, 2002, Biochemical and biophysical research communications.

A newly discovered member of the fatty acid desaturase gene family: a non-coding, antisense RNA gene to delta5-desaturase.

S. Clarke, T. Gettys, T. Dreesen, 2006, Prostaglandins, leukotrienes, and essential fatty acids.

HDL-apoA-I Exchange: Rapid Detection and Association with Atherosclerosis

G. Shearer, M. Budamagunta, J. Genest, 2013, PloS one.

Genetic control of the mouse HDL proteome defines HDL traits, function, and heterogeneity[S]

Deanna L. Plubell, A. Lusis, Calvin Pan, 2019, Journal of Lipid Research.

Genetic control of the HDL proteome

Deanna L. Plubell, A. Lusis, Calvin Pan, 2018, bioRxiv.

ABCG1 regulates mouse adipose tissue macrophage cholesterol levels and ratio of M1 to M2 cells in obesity and caloric restriction[S]

R. Leboeuf, E. Tarling, Chongren Tang, 2015, Journal of Lipid Research.

Impact of mifepristone, a glucocorticoid/progesterone antagonist, on HDL cholesterol, HDL particle concentration, and HDL function.

R. Krauss, J. Kane, J. Purnell, 2012, The Journal of clinical endocrinology and metabolism.

A Cluster of Proteins Implicated in Kidney Disease Is Increased in High-Density Lipoprotein Isolated from Hemodialysis Subjects.

I. D. de Boer, J. Himmelfarb, M. Afkarian, 2015, Journal of proteome research.

Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosis.

D. Dichek, Nagadhara Dronadula, Chongren Tang, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Factors controlling nascent high-density lipoprotein particle heterogeneity: ATP-binding cassette transporter A1 activity and cell lipid and apolipoprotein AI availability

M. Phillips, Chongren Tang, N. Lyssenko, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Plasminogen promotes cholesterol efflux by the ABCA1 pathway.

M. Koschinsky, D. Dichek, G. Getz, 2017, JCI insight.

The cell cholesterol exporter ABCA1 as a protector from cardiovascular disease and diabetes.

J. Oram, Chongren Tang, 2009, Biochimica et biophysica acta.

ApoE4 Alters ABCA1 Membrane Trafficking in Astrocytes

H. Chui, D. Michaelson, Varun Rawat, 2019, The Journal of Neuroscience.

Diabetes Impairs Cellular Cholesterol Efflux From ABCA1 to Small HDL Particles

G. Jarvik, K. Bornfeldt, J. Segrest, 2020, Circulation research.

Patients With Coronary Endothelial Dysfunction Have Impaired Cholesterol Efflux Capacity and Reduced HDL Particle Concentration.

A. Lerman, T. Vaisar, J. Heinecke, 2016, Circulation research.

Apolipoprotein A-I exchange is impaired in metabolic syndrome patients asymptomatic for diabetes and cardiovascular disease

G. Shearer, O. Savinova, M. Oda, 2017, PloS one.

Regulation of ABCA1 functions by signaling pathways.

Yuhua Liu, Chongren Tang, 2012, Biochimica et biophysica acta.

Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity[S]

T. Vaisar, J. Heinecke, A. Suffredini, 2015, Journal of Lipid Research.

Diabetes reduces the cholesterol exporter ABCA1 in mouse macrophages and kidneys1

K. Bornfeldt, Jenny E. Kanter, R. Leboeuf, 2010, Journal of Lipid Research.

Testosterone replacement in hypogonadal men alters the HDL proteome but not HDL cholesterol efflux capacity[S]

T. Vaisar, A. Matsumoto, J. Heinecke, 2012, Journal of Lipid Research.

Acute sex steroid withdrawal increases cholesterol efflux capacity and HDL-associated clusterin in men

A. Hoofnagle, J. Heinecke, J. Amory, 2012, Steroids.

Acyl-CoA synthetase 1 is required for oleate and linoleate mediated inhibition of cholesterol efflux through ATP-binding cassette transporter A1 in macrophages.

K. Bornfeldt, Jenny E. Kanter, J. Oram, 2012, Biochimica et biophysica acta.

Phospholipid transfer protein interacts with and stabilizes ABCA 1 and enhances cholesterol efflux from cells *

A. Vaughan, J. Albers, J. Oram, 2003 .

N-terminal eGFP-tagging of rabbit apolipoprotein A-I decreases expression and impairs cholesterol-efflux activity.

D. Dichek, D. Palmer, Chongren Tang, 2023, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Regulation of human Δ-6 desaturase gene transcription Published, JLR Papers in Press, January 16, 2003. DOI 10.1194/jlr.M200195-JLR200

Manabu T. Nakamura, S. Clarke, Chongren Tang, 2003, Journal of Lipid Research.

Modulation of adipose tissue lipolysis and body weight by high-density lipoproteins in mice

S. Subramanian, A. Chait, R. Leboeuf, 2014, Nutrition & Diabetes.