E. Bel

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Loss of asthma control and activation of coagulation and fibrinolysis

R. Lutter, P. Sterk, P. Kamphuisen, 2016, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

The long-term effects of nedocromil sodium and beclomethasone dipropionate on bronchial responsiveness to methacholine in nonatopic asthmatic subjects.

P. Sterk, E. Bel, J. Dijkman, 1990, The American review of respiratory disease.

Exhaled nitric oxide predicts lung function decline in difficult-to-treat asthma

K. Rabe, P. Sterk, S. Gauw, 2008, European Respiratory Journal.

Sputum induction in severe asthma by a standardized protocol: predictors of excessive bronchoconstriction.

A. Zwinderman, K. Rabe, P. Sterk, 2001, American journal of respiratory and critical care medicine.

Lung function and sputum characteristics of patients with severe asthma during an induced exacerbation by double-blind steroid withdrawal.

P. Sterk, E. Bel, H. Smits, 1999, American journal of respiratory and critical care medicine.

The determinants of airway hyperresponsiveness to hypertonic saline in atopic asthma in vivo. Relationship with sub‐populations of peripheral blood leucocytes

P. Sterk, J. Sont, P. Booms, 1993, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Difficult/therapy-resistant asthma: the need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel therapies. ERS Task Force on Difficult/Therapy-Resistant Asthma. European Respiratory Society.

D. Postma, P. Burney, G. Joos, 1999, The European respiratory journal.

Auranofin in the treatment of steroid dependent asthma: a double blind study.

A. Zwinderman, E. Bel, J. Dijkman, 1992, Thorax.

The use of induced sputum in clinical trials

I. Pavord, P. Sterk, R. Djukanović, 2002, European Respiratory Journal.

Maximal airway narrowing to inhaled leukotriene D4 in normal subjects. Comparison and interaction with methacholine.

P. Sterk, E. Bel, J. Dijkman, 1987, The American review of respiratory disease.

Repeated virus identification in the airways of patients with mild and severe asthma during prospective follow‐up

R. Lutter, P. Sterk, A. Spanevello, 2011, Allergy.

The effect of inhaled budesonide on the maximal degree of airway narrowing to leukotriene D4 and methacholine in normal subjects in vivo.

P. Sterk, E. Bel, H. van der Veen, 1989, The American review of respiratory disease.

The excretion of leukotriene E4 into urine following inhalation of leukotriene D4 by human individuals.

P. Sterk, J. Vliegenthart, G. Veldink, 1987, Biochemical and biophysical research communications.

The effect of an inhaled neutral endopeptidase inhibitor, thiorphan, on airway responses to neurokinin A in normal humans in vivo.

P. Sterk, E. Bel, J. den Hartigh, 1992, The American review of respiratory disease.

The shape of the dose-response curve to inhaled bronchoconstrictor agents in asthma and in chronic obstructive pulmonary disease.

P. Sterk, E. Bel, 1991, The American review of respiratory disease.

The effect of mk-591, a potent oral leukotriene biosynthesis inhibitor, on allergen-induced airway responses in asthmatic subjects

P. Sterk, Z. Diamant, E. Bel, 1993 .

External validation of blood eosinophils, FENO and serum periostin as surrogates for sputum eosinophils in asthma

R. Lutter, A. Sousa, P. Sterk, 2014, Thorax.

The severity of breathlessness during challenges with inhaled methacholine and hypertonic saline in atopic asthmatic subjects. The relationship with deep breath-induced bronchodilation.

P. Sterk, J. Sont, P. Booms, 1995, American journal of respiratory and critical care medicine.

The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo.

P. Sterk, Z. Diamant, D Hilliard, 1995, The Journal of allergy and clinical immunology.

Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment. The AMPUL Study Group.

J. Vandenbroucke, P. Sterk, E. Bel, 1999, American journal of respiratory and critical care medicine.

Long-term effects of a long-acting beta 2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma.

A. Zwinderman, A. Zwinderman, P. Sterk, 1992, The New England journal of medicine.

Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma

E. Nizankowska-Mogilnicka, S. Dahlén, S. Holgate, 2014, Allergy.

The effect of an inhaled leukotriene antagonist, L-648,051, on early and late asthmatic reactions and subsequent increase in airway responsiveness in man.

P. Sterk, E. Bel, J. Dijkman, 1990, The Journal of allergy and clinical immunology.

P138 An innovative approach to study design: using electronic medical records to inform the feasibility and design of the novelty study (a novel observational longitudinal study on patients with asthma and/or COPD)

B. Make, C. Janson, J. Vestbo, 2016, Thorax.

Risk factors of frequent exacerbations in difficult-to-treat asthma

A. Zwinderman, K. Rabe, P. Sterk, 2005, European Respiratory Journal.

Recurrent exacerbations in severe asthma are associated with enhanced airway closure during stable episodes.

P. Sterk, E. Bel, J. I. '. in 't Veen, 2000, American journal of respiratory and critical care medicine.

Impaired perception of dyspnea in patients with severe asthma. Relation to sputum eosinophils.

P. Sterk, E. Bel, H. Smits, 1998, American journal of respiratory and critical care medicine.

Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers

C. Auffray, K. Bønnelykke, H. Bisgaard, 2018, Metabolomics.

The long‐term effect of nedocromil sodium on the maximal degree of airway narrowing to methacholine in atopic asthmatic subjects

P. Sterk, J. Sont, J. Dijkman, 1992, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

The effect of inhaled corticosteroids on the maximal degree of airway narrowing to methacholine in asthmatic subjects.

A. Zwinderman, A. Zwinderman, P. Sterk, 1991, The American review of respiratory disease.

The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma

D. Postma, R. Pauwels, P. Howarth, 2003, European Respiratory Journal.

Gene expression profiling of laser microdissected airway smooth muscle tissue in asthma and atopy

F. Baas, R. Lutter, C. Y. Yick, 2014, Allergy.

Frequent exacerbators – a distinct phenotype of severe asthma

E. Nizankowska-Mogilnicka, S. Dahlén, B. Dahlén, 2011, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

External validation of exhaled breath profiling using an electronic nose in the discrimination of asthma with fixed airways obstruction and chronic obstructive pulmonary disease

M P van der Schee, A. Zwinderman, E. Bel, 2011, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Extracellular matrix in airway smooth muscle is associated with dynamics of airway function in asthma

R. Lutter, P. Sterk, C. Y. Yick, 2012, Allergy.

Small airways, big challenge

P. Sterk, E. Bel, 2011, European Respiratory Review.

Airway inflammation in obese and nonobese patients with difficult‐to‐treat asthma

K. Rabe, P. Sterk, E. Bel, 2008, Allergy.

Monitoring exhaled Nitric Oxide (FENO) To Tailor The Lowest Effective Dose Of Oral Corticosteroids In Severe Asthma (MONOSA-Study)

A. Zwinderman, P. Sterk, J. Sont, 2010, Asian Test Symposium.

Correction

I. Pavord, B. Make, A. Agustí, 2017, Thorax.

Bronchial hyperresponsiveness: the need for a distinction between hypersensitivity and excessive airway narrowing.

P. Sterk, E. Bel, 1989, The European respiratory journal.