Y. Amrani

K. Jordan-Sciutto, D. Goncharov, R. Panettieri, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Selected Contribution: TNF-α modulates murine tracheal rings responsiveness to G-protein-coupled receptor agonists and KCl

R. Panettieri, O. Tliba, Y. Amrani, 2003 .

Modulation of calcium homeostasis as a mechanism for altering smooth muscle responsiveness in asthma

R. Panettieri, Y. Amrani, 2002, Current opinion in allergy and clinical immunology.

Airway smooth muscle: contraction and beyond.

R. Panettieri, Y. Amrani, 2003, The international journal of biochemistry & cell biology.

Cytokines induce an early steroid resistance in airway smooth muscle cells: novel role of interferon regulatory factor-1.

S. Keslacy, O. Tliba, Y. Amrani, 2008, American journal of respiratory cell and molecular biology.

Potential Role of Mast Cells in Regulating Corticosteroid Insensitivity in Severe Asthma.

P. Bradding, A. Hussain, A. Alzahrani, 2021, Advances in experimental medicine and biology.

TGF-β potentiates airway smooth muscle responsiveness to bradykinin

E. Puré, R. Panettieri, D. Jain, 2005 .

Airway smooth muscle cells are insensitive to the anti-proliferative effects of corticosteroids: The novel role of insulin growth factor binding Protein-1 in asthma.

R. Panettieri, O. Tliba, Y. Amrani, 2019, Immunobiology.

Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth-muscle cells. Modulation by cyclic adenosine monophosphate.

A. Ammit, R. Panettieri, R. Penn, 2000, American journal of respiratory cell and molecular biology.

Dexamethasone Pathway That Is Only Partially Sensitive to B-dependent Signaling Κ Involves an Nf- Human Tracheal Smooth Muscle Cells Up-regulation of Icam-1 by Cytokines In

R. Panettieri, A. Lazaar, Y. Amrani, 2013 .

GTS-21, an α7nAChR agonist, suppressed the production of key inflammatory mediators by PBMCs that are elevated in COPD patients and associated with impaired lung function

M. Oumouna, Y. Amrani, R. Djidjik, 2020, Immunobiology.

Functional KCa3.1 Channels Regulate Steroid Insensitivity in Bronchial Smooth Muscle Cells

C. Brightling, P. Bradding, L. Chachi, 2013, The Journal of Immunology.

Cytokines alter glucocorticoid receptor phosphorylation in airway cells: role of phosphatases.

R. Honkanen, O. Tliba, Y. Amrani, 2012, American journal of respiratory cell and molecular biology.

Steroid Insensitivity in Bronchial Smooth 3.1 Channels Regulate Ca Functional K

C. Brightling, P. Bradding, Y. Amrani, 2022 .

Sphingosine 1‐phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma

S. Spiegel, S. Peters, A. Ammit, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Tumor Necrosis Factor-a – Induced Secretion of RANTES and Interleukin-6 from Human Airway Smooth-Muscle Cells Modulation by Cyclic Adenosine Monophosphate

A. Ammit, R. Panettieri, R. Penn, 2000 .

Abnormal corticosteroid signalling in airway smooth muscle: mechanisms and perspectives for the treatment of severe asthma

L. Chachi, A. Gavrila, O. Tliba, 2015, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

IFN-γ inhibits human airway smooth muscle cell proliferation by modulating the E2F-1/Rb pathway

D. Choubey, A. Eszterhas, R. Panettieri, 2003 .

Chapter 17 – Airway Smooth Muscle

R. Panettieri, V. Krymskaya, A. Lazaar, 2002 .

Comparative action of new highly potent bradykinin receptor antagonists in the guinea-pig trachea.

J. Gies, Y. Amrani, A. Trifilieff, 1993, European journal of pharmacology.

Targeting TNF-α: A novel therapeutic approach for asthma

Christopher E. Brightling, C. Brightling, Yassine Amrani, 2008 .

Tumor necrosis factor alpha potentiates the increase in cytosolic free calcium induced by bradykinin in guinea-pig tracheal smooth muscle cells.

C. Bronner, Y. Amrani, 1993, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.

Bradykinin induces interleukin-6 production in human airway smooth muscle cells: modulation by Th2 cytokines and dexamethasone.

R. Panettieri, Chien-Da Huang, O. Tliba, 2003, American journal of respiratory cell and molecular biology.

Targeting TNF-α: A novel therapeutic approach for asthma

C. Brightling, Y. Amrani, M. Berry, 2008 .

Sphingosine‐1‐phosphate stimulates contraction of human airway smooth muscle cells

S. Spiegel, H. Rosenfeldt, R. Panettieri, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cytokines induce airway smooth muscle cell hyperresponsiveness to contractile agonists

R. Panettieri, Y. Amrani, 1998, Thorax.

Mechanisms underlying TNF-α effects on agonist-mediated calcium homeostasis in human airway smooth muscle cells.

R. Panettieri, V. Krymskaya, Y. Amrani, 1997, American journal of physiology. Lung cellular and molecular physiology.

Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: role of CD38/cyclic adenosine diphosphate ribose pathway.

Steven M. Miller, R. Panettieri, D. Deshpande, 2004, American journal of respiratory cell and molecular biology.

Interferon-gamma modulates cysteinyl leukotriene receptor-1 expression and function in human airway myocytes.

R. Panettieri, S. Shore, P. Moore, 2001, American journal of respiratory and critical care medicine.

Vitamin D Attenuates Cytokine‐Induced Remodeling in Human Fetal Airway Smooth Muscle Cells

Richard J Martin, A. Faksh, M. Thompson, 2015, Journal of cellular physiology.

β2-Adrenoceptor Function in Asthma.

P. Bradding, Y. Amrani, 2017, Advances in immunology.

Counterregulation of beta(2)-adrenoceptor function in human mast cells by stem cell factor.

G. Cruse, P. Bradding, L. Chachi, 2010, The Journal of allergy and clinical immunology.

D prostanoid receptor 2 (chemoattractant receptor–homologous molecule expressed on TH2 cells) protein expression in asthmatic patients and its effects on bronchial epithelial cells

C. Brightling, Y. Amrani, S. Stinson, 2015, The Journal of allergy and clinical immunology.

Tumor Necrosis Factor Alpha

C. Brightling, L. Chachi, Y. Amrani, 2011 .

Essential role of IFNbeta and CD38 in TNFalpha-induced airway smooth muscle hyper-responsiveness.

R. Panettieri, S. Keslacy, D. Jain, 2008, Immunobiology.

Essential role of IFN β and CD38 in TNF α -induced airway smooth muscle hyper-responsiveness

R. Panettieri, S. Keslacy, D. Jain, 2008 .

TNF-alpha and calcium signaling in airway smooth muscle cells: a never-ending story with promising therapeutic relevance.

Y. Amrani, 2007, American journal of respiratory cell and molecular biology.

Effect of the plant derivative Compound A on the production of corticosteroid-resistant chemokines in airway smooth muscle cells.

C. Brightling, L. Chachi, A. Gavrila, 2015, American journal of respiratory cell and molecular biology.

The Plant Derivative Compound A Inhibits the Production of Corticosteroid-resistant Chemokines by Airway Smooth Muscle Cells.

C. Brightling, L. Chachi, A. Gavrila, 2015 .

Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells.

R. Panettieri, I. Rogatsky, S. Keslacy, 2010, American journal of respiratory cell and molecular biology.

CD38 Expression Is Insensitive to Steroid Action in Cells Treated with Tumor Necrosis Factor‐{alpha} and Interferon‐{gamma} by a Mechanism Involving the Up‐Regulation of the Glucocorticoid Receptor beta Isoform

O. Tliba, Y. Amrani, 2006, Molecular pharmacology.

CD38 Expression Is Insensitive to Steroid Action in Cells Treated with Tumor Necrosis Factor-α and Interferon-γ by a Mechanism Involving the Up-Regulation of the Glucocorticoid Receptor β Isoform

J. Cidlowski, O. Tliba, Y. Amrani, 2006, Molecular Pharmacology.

Immunopathogenesis of severe asthma.

S. Gupta, C. Brightling, Y. Amrani, 2011, Current pharmaceutical design.

Vascular endothelial growth factor-induced secretion of fibronectin is ERK dependent.

E. Goncharova, V. Krymskaya, A. Lazaar, 2004, American journal of physiology. Lung cellular and molecular physiology.

Modulation of Airway Smooth Muscle Contractile Function by TNFα and IL-13 and Airway Hyperresponsiveness in Asthma

Y. Amrani, 2014 .

TGF-beta potentiates airway smooth muscle responsiveness to bradykinin.

E. Puré, R. Panettieri, D. Jain, 2005, American journal of physiology. Lung cellular and molecular physiology.

TNF-[alpha] modulates murine tracheal rings responsiveness to G-protein-coupled receptor agonists and KCl.

R. Panettieri, O. Tliba, Y. Amrani, 2003, Journal of applied physiology.

Mechanisms underlying TNF-alpha effects on agonist-mediated calcium homeostasis in human airway smooth muscle cells.

R. Panettieri, V. Krymskaya, Y. Amrani, 1997, The American journal of physiology.

Potentiation by tumour necrosis factor‐α of calcium signals induced by bradykinin and carbachol in human tracheal smooth muscle cells

C. Bronner, N. Martinet, Y. Amrani, 1995, British journal of pharmacology.

Increased β2‐adrenoceptor phosphorylation in airway smooth muscle in severe asthma: possible role of mast cell‐derived growth factors

R. Panettieri, P. Bradding, C. Koziol-White, 2018, Clinical and experimental immunology.

IFN-γ-induced JAK/STAT, but not NF-κB, signaling pathway is insensitive to glucocorticoid in airway epithelial cells.

O. Tliba, Y. Amrani, Danielle O'Connell, 2015, American journal of physiology. Lung cellular and molecular physiology.

Tumor necrosis factor receptor (TNFR) 1, but not TNFR2, mediates tumor necrosis factor-alpha-induced interleukin-6 and RANTES in human airway smooth muscle cells: role of p38 and p42/44 mitogen-activated protein kinases.

A. Ammit, R. Panettieri, Y. Amrani, 2001, Molecular pharmacology.

altered smooth muscle response to isoprostane decreased pulmonary arterial nitric oxide release and exposure in the newborn rat results in

Jullie W Pan, A. Tanswell, S. Wedgwood, 2015 .

CD38 Expression Is Insensitive to Steroid Action in Cells Treated with Tumor Necrosis Factor- (cid:1) and Interferon- (cid:2) by a Mechanism Involving the Up-Regulation of the Glucocorticoid Receptor (cid:3) Isoform

J. Cidlowski, O. Tliba, Y. Amrani, 2006 .

Involvement of B2 receptors in the bradykinin‐induced relaxation of guinea‐pig isolated trachea

Y. Amrani, A. Trifilieff, Y. Landry, 1995, British journal of pharmacology.

A model of human lung fibrogenesis for the assessment of anti-fibrotic strategies in idiopathic pulmonary fibrosis

C. Newby, P. Bradding, Y. Amrani, 2018, Scientific Reports.

A comparison of β2-adrenoceptor desensitisation induced by olodaterol and formoterol in human lung mast cells and airway smooth muscle cells

P. Bradding, L. Chachi, Y. Amrani, 2013 .

Is airway smooth muscle the "missing link" modulating airway inflammation in asthma?

R. Panettieri, O. Tliba, Y. Amrani, 2008, Chest.

pathway is insensitive to glucocorticoid in airway

O. Tliba, Y. Amrani, B. Bouazza, 2015 .

Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: modulation by glucocorticoids and beta-agonists.

G. O'Neill, A. Ammit, R. Panettieri, 2002, American Journal of Respiratory Cell and Molecular Biology.

Oxygen dose responsiveness of human fetal airway smooth muscle cells.

Richard J Martin, M. Thompson, H. Pandya, 2012, American journal of physiology. Lung cellular and molecular physiology.

Transcriptional regulation of CD38 expression by tumor necrosis factor- (cid:1) in human airway smooth muscle cells: role of NF- (cid:2) B and sensitivity to glucocorticoids

R. Panettieri, D. Deshpande, B. Kang, 2006 .

G-Protein-coupled receptor agonists differentially regulate basal or tumor necrosis factor-α-stimulated activation of interleukin-6 and RANTES in human airway smooth muscle cells

H. Kuo, A. Ammit, R. Panettieri, 2005 .

Engagement of human PECAM-1 (CD31) on human endothelial cells increases intracellular calcium ion concentration and stimulates prostacyclin release.

I. Gurubhagavatula, D. Praticò, R. Panettieri, 1998, The Journal of clinical investigation.

Histamine mobilizes intracellular Ca2+-pools sensitive to thapsigargin in cultured guinea-pig tracheal smooth muscle cells

C. Bronner, Y. Amrani, 1995, Inflammation Research.

Response to C3a, mast cells, and asthma

R. Panettieri, Y. Amrani, A. Zaidi, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Tumor necrosis factor alpha modulates airway smooth muscle function via the autocrine action of interferon beta.

R. Panettieri, O. Tliba, Y. Amrani, 2003, The Journal of biological chemistry.

Role of Vitamin D Deficiency in Allergic Diseases: Is this Due to an Impaired Patients' Response to Corticosteroid Therapy?

I. Adcock, Y. Amrani, 2014 .

Fetal human airway smooth muscle cell production of leukocyte chemoattractants is differentially regulated by fluticasone

H. Pandya, C. Pabelick, Y. Amrani, 2015, Pediatric Research.

[Interaction between tumor necrosis factor-alpha and the smooth muscle cells of the airway: implication in the physiopathology of asthma].

C. Bronner, M. Aubier, Y. Amrani, 1996, Revue des maladies respiratoires.

Effect of lipopolysaccharide on bradykinin- and histamine-induced increase in cytosolic free calcium in cultured guinea-pig tracheal smooth muscle cells

C. Bronner, Y. Amrani, Y. Landry, 1994, Neuropeptides.

Smooth Muscle Hypercontractility in Airway Hyperresponsiveness: Innate, Acquired, or Nonexistent?

M. Grunstein, Y. Amrani, Y. Bossé, 2013, Journal of allergy.

Transcriptional regulation of CD38 expression by tumor necrosis factor‐α in human airway smooth muscle cells: role of NF‐κB and sensitivity to glucocorticoids

Bit‐Na Kang, K. G. Tirumurugaan, Deepak A. Deshpande, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

TARC attenuates the development of asthma in mice

Y. Amrani, 2001 .

Microsoft Word-14123389-file00

E. Goncharova, D. Goncharov, R. Panettieri, 2009 .

ROLE DE L'EPITHELIUM BRONCHIQUE DANS L'ASTHME

Da Silva R.C.M.A., Y Amrani, Y Landry, 1993 .

INHIBITION OF TNF α -INDUCIBLE INFLAMMATORY GENES BY IFN γ IS ASSOCIATED WITH ALTERED NF- κ B TRANSACTIVATION AND ENHANCED HDAC ACTIVITY.

S. Keslacy, O. Tliba, Y. Amrani, 2006 .

An RGS4-Mediated Phenotypic Switch of Bronchial Smooth Muscle Cells Promotes Fixed Airway Obstruction in Asthma

C. Brightling, P. Cooper, K. Druey, 2012, PloS one.

Airway Smooth Muscle

R. Panettieri, V. Krymskaya, O. Tliba, 2009 .

TNF α differentially regulates the expression of pro-inflammatory genes in human airway smooth muscle cells by activation of IFN β -dependent CD38 pathway

R. Panettieri, T. Walseth, O. Tliba, 2004 .

Targeting TNF-alpha: a novel therapeutic approach for asthma.

Christopher Brightling, C. Brightling, Yassine Amrani, 2008, The Journal of allergy and clinical immunology.

Activation of tumor necrosis factor receptor 1 in airway smooth muscle: a potential pathway that modulates bronchial hyper-responsiveness in asthma?

R. Panettieri, Y. Amrani, Hang Chen, 2000, Respiratory research.

Non-genomic Effects of Glucocorticoids: An Updated View.

Reynold A Panettieri, R. Ostrom, R. Panettieri, 2019, Trends in pharmacological sciences.

Activation of p55 tumor necrosis factor-alpha receptor-1 coupled to tumor necrosis factor receptor-associated factor 2 stimulates intercellular adhesion molecule-1 expression by modulating a thapsigargin-sensitive pathway in human tracheal smooth muscle cells.

R. Panettieri, A. Lazaar, K Amin, 2000, Molecular pharmacology.

Gene expression profiling of flaxseed in mouse lung tissues-modulation of toxicologically relevant genes

L. Showe, Y. Amrani, M. Christofidou-Solomidou, 2012, BMC Complementary and Alternative Medicine.

Stressed out - The role of oxidative stress in airway smooth muscle dysfunction in asthma and COPD.

C. Brightling, Y. Amrani, R. Saunders, 2022, Free radical biology & medicine.

MechanismsRemodeling in Asthma: Therapeutic Implications of

Richard J Martin, J. Whitsett, Ji-hang Ju, 2015 .

Interferon β Augments Tuberous Sclerosis Complex 2 (TSC2)-Dependent Inhibition of TSC2-Null ELT3 and Human Lymphangioleiomyomatosis-Derived Cell Proliferation

E. Goncharova, D. Goncharov, R. Panettieri, 2008, Molecular Pharmacology.

Lipoxin A4 Attenuates Constitutive and TGF-β1–Dependent Profibrotic Activity in Human Lung Myofibroblasts

P. Bradding, C. Feghali-Bostwick, Y. Amrani, 2015, The Journal of Immunology.

Tensin1 expression and function in chronic obstructive pulmonary disease

C. Brightling, B. Gooptu, P. Bradding, 2019, Scientific Reports.

Human lung myofibroblast TGFβ1-dependent Smad2/3 signalling is Ca2+-dependent and regulated by KCa3.1 K+ channels

H. Wulff, P. Bradding, C. Feghali-Bostwick, 2015, Fibrogenesis & tissue repair.

TGFβ 1-dependent Smad 2 / 3 signalling is Ca 2 +-dependent and regulated by KCa 3 . 1 K + channels

H. Wulff, P. Bradding, C. Feghali-Bostwick, 2015 .

Increased constitutive αSMA and Smad2/3 expression in idiopathic pulmonary fibrosis myofibroblasts is KCa3.1-dependent

H. Wulff, P. Bradding, C. Feghali-Bostwick, 2014, Respiratory Research.

Toll-like receptor 9 activation induces expression of membrane-bound B-cell activating factor (BAFF) on human B cells and leads to increased proliferation in response to both soluble and membrane-bound BAFF.

M. Browning, Y. Amrani, Eman Y. Abu-rish, 2013, Rheumatology.

Ozone inhalation induces exacerbation of eosinophilic airway inflammation and hyperresponsiveness in allergen‐sensitized mice

R. Panettieri, M. Salmon, A. Haczku, 2008, Allergy.

Airway smooth muscle cell as an inflammatory cell: lessons learned from interferon signaling pathways.

O. Tliba, Y. Amrani, 2008, Proceedings of the American Thoracic Society.

A model of human lung fibrogenesis for the assessment of anti-fibrotic strategies in idiopathic pulmonary fibrosis

C. Newby, P. Bradding, Y. Amrani, 2018, Scientific Reports.

Signal Transducer and Activator of Transcription 3 Is Required for Abnormal Proliferation and Survival of TSC2-Deficient Cells: Relevance to Pulmonary Lymphangioleiomyomatosis

E. Goncharova, D. Goncharov, R. Panettieri, 2009, Molecular Pharmacology.

Mast cell activation involves plasma membrane potential‐ and thapsigargin‐sensitive intracellular calcium pools

C. Bronner, O. Kassel, Y. Amrani, 1995, Fundamental & clinical pharmacology.

Human Lung Myofibroblasts Dependent Profibrotic Activity in - 1 β TGF- Attenuates Constitutive and 4 Lipoxin A

P. Bradding, C. Feghali-Bostwick, Y. Amrani, 2015 .

The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells

F. Syed, R. Panettieri, B. Amegadzie, 2005, Respiratory research.

Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction

K. Chung, A. Tobin, E. Kostenis, 2016, Proceedings of the National Academy of Sciences.

New Tricks for an Old Dog: Biased GPCR Agonism of an M4 Muscarinic Acetylcholine Receptor Antagonist in Airway Smooth Muscle Cells

Y. Amrani, 2022, American journal of respiratory cell and molecular biology.

Up-regulation of ICAM-1 by cytokines in human tracheal smooth muscle cells involves an NF-kappa B-dependent signaling pathway that is only partially sensitive to dexamethasone.

R. Panettieri, A. Lazaar, Y. Amrani, 1999, Journal of immunology.

Oxygen dose responsiveness of human fetal airway smooth muscle cells.

Richard J Martin, M. Thompson, H. Pandya, 2012, American journal of physiology. Lung cellular and molecular physiology.

Airway smooth muscle modulation and airway hyper-responsiveness in asthma: new cellular and molecular paradigms

Y. Amrani, 2006, Expert review of clinical immunology.

Tumor necrosis factor-alpha differentially regulates the expression of proinflammatory genes in human airway smooth muscle cells by activation of interferon-beta-dependent CD38 pathway.

R. Panettieri, T. Walseth, O. Tliba, 2004, Molecular pharmacology.

Inhibition of Tumor Necrosis Factor-α-Inducible Inflammatory Genes by Interferon-γ Is Associated with Altered Nuclear Factor-κB Transactivation and Enhanced Histone Deacetylase Activity

S. Keslacy, O. Tliba, Y. Amrani, 2006, Molecular Pharmacology.