G. Del Vecchio

Opioid receptor signaling, analgesic and side effects induced by a computationally designed pH-dependent agonist

Marcus Weber, A. Rodríguez-Gaztelumendi, C. Stein, 2018, Scientific Reports.

A nontoxic pain killer designed by modeling of pathological receptor conformations

V. Durmaz, A. Rodríguez-Gaztelumendi, C. Stein, 2017, Science.

pKa of opioid ligands as a discriminating factor for side effects

Marcus Weber, A. Rodríguez-Gaztelumendi, C. Stein, 2019, Scientific Reports.

Modulation of μ‐opioid receptor activation by acidic pH is dependent on ligand structure and an ionizable amino acid residue

C. Stein, G. Del Vecchio, Johanna Meyer, 2019, British journal of pharmacology.

Novel Opioid Analgesics and Side Effects.

C. Stein, V. Spahn, G. Del Vecchio, 2017, ACS chemical neuroscience.