David C McGowan

Characterization of a dengue NS4B inhibitor originating from an HCV small molecule library

Peggy Geluykens, M. Van Loock, B. Devogelaere, 2017, Antiviral research.

Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity.

Xin Huang, David Powers, Daniela Metz, 2006, Journal of medicinal chemistry.

Novel Pyrimidine Toll-like Receptor 7 and 8 Dual Agonists to Treat Hepatitis B Virus.

J. Vlach, F. Pauwels, E. Arnoult, 2016, Journal of medicinal chemistry.

2,4-Diaminoquinazolines as Dual Toll-like Receptor (TLR) 7/8 Modulators for the Treatment of Hepatitis B Virus.

V. Pande, F. Pauwels, T. Jonckers, 2018, Journal of medicinal chemistry.

Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055.

M. Cummings, B. Devogelaere, Lili Hu, 2012, Bioorganic & medicinal chemistry letters.

Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH)

J. Deval, J. Symons, D. Misner, 2020, bioRxiv.

Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.

P. Gallant, A. Oliveira-dos-Santos, J. Newcomb, 2008, Journal of medicinal chemistry.

Discovery and early development of TMC647055, a non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase.

M. Cummings, B. Devogelaere, Lili Hu, 2014, Journal of medicinal chemistry.