Hans-Peter Spirkl

Do Carboxylic/Sulfonic Acid Halides Really Present a Mutagenic and Carcinogenic Risk as Impurities in Final Drug Products?

Alexander Amberg, Angela White, Andreas Czich, 2015 .

Nonclinical safety evaluation of a novel ionizable lipid for mRNA delivery.

Marie-Clotilde Bernard, A. Amberg, Hans-Peter Spirkl, 2022, Toxicology and applied pharmacology.

Computational Models for Human and Animal Hepatotoxicity with a Global Application Scope.

Alexander Amberg, Andreas Czich, Denis Mulliner, 2016, Chemical research in toxicology.

A pharma-wide approach to address the genotoxicity prediction of primary aromatic amines

Mick D. Fellows, Robert A. Jolly, Alexander Amberg, 2018, Computational Toxicology.

Evaluation of a statistics-based Ames mutagenicity QSAR model and interpretation of the results obtained.

Nigel Greene, Alex Harding, Alexander Amberg, 2016, Regulatory toxicology and pharmacology : RTP.

It's difficult, but important, to make negative predictions.

Nigel Greene, Alexander Amberg, Susanne Glowienke, 2016, Regulatory toxicology and pharmacology : RTP.

Extending (Q)SARs to incorporate proprietary knowledge for regulatory purposes: A case study using aromatic amine mutagenicity.

Lidiya Stavitskaya, Alexander Amberg, Masamitsu Honma, 2016, Regulatory toxicology and pharmacology : RTP.

Principles and procedures for implementation of ICH M7 recommended (Q)SAR analyses.

Lidiya Stavitskaya, Raymond Kemper, Alexander Amberg, 2016, Regulatory toxicology and pharmacology : RTP.

Extending (Q)SARs to incorporate proprietary knowledge for regulatory purposes: A case study using aromatic amine mutagenicity.

Donald P. Quigley, G. Myatt, K. Cross, 2016, Regulatory toxicology and pharmacology : RTP.