Leigh Ford

发表

Ionic liquids provide unique opportunities for oral drug delivery: structure optimization and in vivo evidence of utility.

Hywel D Williams, Christopher J H Porter, C. Porter, 2014, Chemical communications.

Unlocking the full potential of lipid-based formulations using lipophilic salt/ionic liquid forms.

P. Botti, C. Pouton, C. Porter, 2019, Advanced drug delivery reviews.

Biocompatible Cationic Lipoamino Acids as Counterions for Oral Administration of API-Ionic Liquids

C. Porter, H. Williams, H. Benameur, 2022, Pharmaceutical Research.

The hybrid molecule, VCP746, is a potent adenosine A2B receptor agonist that stimulates anti-fibrotic signalling.

Joanne Baltos, P. White, A. Christopoulos, 2016, Biochemical pharmacology.

Radicals and transition-metal catalysis: an alliance par excellence to increase reactivity and selectivity in organic chemistry.

U. Jahn, Leigh Ford, 2009, Angewandte Chemie.

Transformation of Biopharmaceutical Classification System Class I and III Drugs Into Ionic Liquids and Lipophilic Salts for Enhanced Developability Using Lipid Formulations.

C. Pouton, C. Porter, H. Williams, 2018, Journal of Pharmacy and Science.

Ionic Liquid Forms of Weakly Acidic Drugs in Oral Lipid Formulations: Preparation, Characterization, in Vitro Digestion, and in Vivo Absorption Studies.

C. Porter, H. Williams, P. Scammells, 2017, Molecular pharmaceutics.

Nitrogen-Containing Ionic Liquids: Biodegradation Studies and Utility in Base-Mediated Reactions

M. T. García, R. Singer, P. Scammells, 2015 .

Further studies on the biodegradation of ionic liquids

R. Singer, P. Scammells, M. Garcia, 2010 .

Discovery and in vivo evaluation of alcohol-containing benzothiazoles as potent dual-targeting bacterial DNA supercoiling inhibitors.

J. Palmer, D. Davies, C. Morton, 2014, Bioorganic & medicinal chemistry letters.

Highly functionalized and potent antiviral cyclopentane derivatives formed by a tandem process consisting of organometallic, transition-metal-catalyzed, and radical reaction steps.

R. Pohl, J. Hodek, R. Mackman, 2014, Chemistry.

Catechols as Sources of Hydrogen Atoms in Radical Deiodination and Related Reactions.

P. Renaud, Leigh Ford, Davide Pozzi, 2016, Angewandte Chemie.

Polarity-reversal-catalyzed hydrostannylation reactions : Benzeneselenol-mediated homolytic hydrostannylation of electron-rich olefins

C. Schiesser, Leigh Ford, U. Wille, 2006 .

Grignard Reactions in Pyridinium and Phosphonium Ionic Liquids

R. Singer, P. Scammells, Leigh Ford, 2011 .

Free Radical Hydrostannylation of Unactivated Alkenes with Chiral Trialkylstannanes

C. Schiesser, Leigh Ford, Yvonne Kavanagh, 2011 .

Role of catechol in the radical reduction of B-alkylcatecholboranes in presence of methanol.

P. Renaud, C. Schiesser, Leigh Ford, 2010, Chemical communications.

Transformation of poorly water-soluble drugs into lipophilic ionic liquids enhances oral drug exposure from lipid based formulations.

Hywel D Williams, Christopher J H Porter, Susan A Charman, 2015, Molecular pharmaceutics.

API ionic liquids: probing the effect of counterion structure on physical form and lipid solubility

C. Porter, H. Williams, H. Benameur, 2020, RSC advances.

Cyclosporin Structure and Permeability: From A to Z and Beyond.

Dallas B. Warren, C. Pouton, D. Chalmers, 2021, Journal of medicinal chemistry.

Enhancing the Oral Absorption of Kinase Inhibitors Using Lipophilic Salts and Lipid-Based Formulations.

David M. Shackleford, C. Pouton, C. Porter, 2018, Molecular pharmaceutics.

Lipophilic Salts and Lipid-Based Formulations: Enhancing the Oral Delivery of Octreotide

C. Pouton, P. Thompson, C. Porter, 2021, Pharmaceutical Research.

Ionic Liquid Forms of the Antimalarial Lumefantrine in Combination with LFCS Type IIIB Lipid-Based Formulations Preferentially Increase Lipid Solubility, In Vitro Solubilization Behavior and In Vivo Exposure

C. Porter, H. Williams, H. Benameur, 2019, Pharmaceutics.

Stabilising disproportionation of lipophilic ionic liquid salts in lipid-based formulations.

C. Porter, H. Williams, H. Benameur, 2021, International journal of pharmaceutics.

Computational and Experimental Models of Type III Lipid-Based Formulations of Loratadine Containing Complex Nonionic Surfactants.

Dallas B. Warren, C. Pouton, D. Chalmers, 2021, Molecular pharmaceutics.

Molecular Dynamics Simulations and Experimental Results Provide Insight into Clinical Performance Differences between Sandimmune® and Neoral® Lipid-Based Formulations

Dallas B. Warren, C. Pouton, D. Chalmers, 2021, Pharmaceutical Research.