P. Gillespie

发表

Discovery of novel and potent leukotriene B4 receptor antagonists. Part 1.

Y. Li, N. Fotouhi, Romyr Dominique, 2010, Journal of medicinal chemistry.

Potent MCH-1 receptor antagonists from cis-1,4-diaminocyclohexane-derived indane analogs.

S. So, Y. Qian, Yonglin Ren, 2013, Bioorganic & medicinal chemistry letters.

Discovery of 1-arylcarbonyl-6,7-dimethoxyisoquinoline derivatives as glutamine fructose-6-phosphate amidotransferase (GFAT) inhibitors.

S. So, Shaoqing Chen, Nam T Le, 2011, Bioorganic & medicinal chemistry letters.

Design and synthesis of 2-N-substituted indazolone derivatives as non-carboxylic acid glycogen synthase activators.

Qing Xiang, Xiaolei Zhang, Y. Qian, 2013, Bioorganic & medicinal chemistry letters.

N-substituted sultam carboxylic acids as novel glycogen synthase activators

Qing Xiang, Xiaolei Zhang, Y. Qian, 2013 .

A selective phosphatase of regenerating liver phosphatase inhibitor suppresses tumor cell anchorage-independent growth by a novel mechanism involving p130Cas cleavage.

N. Fotouhi, D. Heimbrook, J. Reidhaar-Olson, 2008, Cancer research.

Identification of RO4597014, a Glucokinase Activator Studied in the Clinic for the Treatment of Type 2 Diabetes.

S. Berthel, Y. Qian, D. Choi, 2013, ACS medicinal chemistry letters.

Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primates.

Y. Li, N. Fotouhi, K. Dabbagh, 2010, Prostaglandins & other lipid mediators.

Discovery and optimization of 2-phenyloxazole derivatives as diacylglycerol acyltransferase-1 inhibitors.

Yingsi Chen, Y. Qian, R. Taub, 2011, Bioorganic & medicinal chemistry letters.

Discovery of camphor-derived pyrazolones as 11β-hydroxysteroid dehydrogenase type 1 inhibitors.

S. So, Yonglin Ren, R. Taub, 2014, Bioorganic & medicinal chemistry letters.

Conformational analysis of dipeptide mimetics

P. Gillespie, G. Olson, J. Cicariello, 1997 .

Discovery of novel non-carboxylic acid 5-amino-4-cyanopyrazole derivatives as potent and highly selective LPA1R antagonists.

C. Stevenson, V. Roongta, A. Sidduri, 2014, Bioorganic & medicinal chemistry letters.

Rapid one-pot preparation of 2-substituted benzimidazoles from 2-nitroanilines using microwave conditions

J. Scicinski, P. Gillespie, D. VanVliet, 2005 .

Rapid One-Pot Preparation of 2-Substituted Benzimidazoles from 2-Nitroanilines Using Microwave Conditions.

J. Scicinski, P. Gillespie, D. VanVliet, 2006 .

Discovery of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists.

S. So, M. Myers, G. Saha, 2014, Bioorganic & medicinal chemistry letters.

Peptidomimetic compounds that inhibit antigen presentation by autoimmune disease-associated class II major histocompatibility molecules

J. Guenot, S. Berthel, F. Falcioni, 1999, Nature Biotechnology.

Novel 5-desmethylene analogs of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid as potential anticancer agents

P. Gillespie, E. Taylor, Mona Patel, 1992 .

Further acyclic analogs of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid

P. Gillespie, E. Taylor, 1992 .

A public-private partnership to unlock the untargeted kinome.

Julian Blagg, Paul Workman, Bernhard Kuster, 2013, Nature chemical biology.

Hit and Lead identification: efficient practices for drug discovery.

Robert A Goodnow, Paul Gillespie, R. Goodnow, 2007, Progress in medicinal chemistry.

Development of a virtual screening method for identification of "frequent hitters" in compound libraries.

Wolfgang Guba, Petra Schneider, Gisbert Schneider, 2002, Journal of medicinal chemistry.

Transcriptional repression of SKP2 is impaired in MYCN-amplified neuroblastoma.

F. Westermann, M. Schwab, M. Fischer, 2010, Cancer research.

Lead generation: reality check on commonly held views

Nader Fotouhi, Paul Gillespie, Robert Goodnow, Jr., 2008, Expert opinion on drug discovery.

The Hit-to-Lead Process in Drug Discovery

Paul Gillespie, Robert A. Goodnow, R. Goodnow, 2004 .

Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures.

R Crowther, U. Kammlott, J. Guenot, 2000, Journal of medicinal chemistry.

A Crowd‐Based Process and Tool for HTS Hit Triage

Paul Gillespie, Zhengwei Peng, Arjun Narayanan, 2013, Molecular informatics.

Design and synthesis of small molecule interleukin-1 receptor antagonists based on a benzene template.

G L Olson, C M Cook, P. Gillespie, 1998, Drug design and discovery.

A Crowd‐Based Process and Tool for HTS Hit Triage

S. So, W. V. So, M. Weisel, 2013, Molecular informatics.