L. Renzetti

发表

Discovery of novel and potent leukotriene B4 receptor antagonists. Part 1.

Y. Li, N. Fotouhi, Romyr Dominique, 2010, Journal of medicinal chemistry.

Dual bronchodilatory and pulmonary anti‐inflammatory activity of RO5024118, a novel agonist at vasoactive intestinal peptide VPAC2 receptors

M. Cazzola, L. Calzetta, D. Bolin, 2010, British journal of pharmacology.

Themed Section: Analytical Receptor Pharmacology in Drug Discovery

M. Cazzola, L. Calzetta, A. Hicks, 2010 .

A Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry.

A. Keefe, F. Ruebsam, J. Cuozzo, 2020, Journal of medicinal chemistry.

N-Aroyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.

R. Campbell, L. Chen, A. Sidduri, 2002, Bioorganic & medicinal chemistry letters.

The mRNA level of Charcot–Leyden crystal protein/galectin-10 is a marker for CRTH2 activation in human whole blood in vitro

H. Hilton, N. Tare, L. Renzetti, 2010, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primates.

Y. Li, N. Fotouhi, K. Dabbagh, 2010, Prostaglandins & other lipid mediators.

Pharmacological evidence for tumor necrosis factor as a mediator of allergic inflammation in the airways.

J. Tocker, M. Wasserman, S. Tannu, 1996, The Journal of pharmacology and experimental therapeutics.

Nonadrenergic, noncholinergic contractile responses of the guinea pig hilar bronchus involve the preferential activation of tachykinin neurokinin2 receptors.

L. Renzetti, A. Shenvi, C. Buckner, 1992, The Journal of pharmacology and experimental therapeutics.

Cellular and Molecular Characterization of Ozone-Induced Pulmonary Inflammation in the Cynomolgus Monkey

Y. Li, H. Hilton, T. March, 2010, Inflammation.

KU812 cells provide a novel in vitro model of the human IL-33/ST2L axis: functional responses and identification of signaling pathways.

G. Ju, N. Tare, L. Renzetti, 2010, Experimental cell research.

Ro 25-1553: a novel, long-acting vasoactive intestinal peptide agonist. Part I: In vitro and in vivo bronchodilator studies.

R. Garippa, D. Bolin, M. Wasserman, 1994, The Journal of pharmacology and experimental therapeutics.

Effects of Ro 47-0203 on endothelin-1 and sarafotoxin S6c-induced contractions of human bronchus and guinea-pig trachea.

M. Wasserman, L. Renzetti, P. R. Gater, 1996, European journal of pharmacology.

Inhibition of Sephadex-induced lung injury in the rat by Ro 45-2081, a tumor necrosis factor receptor fusion protein.

M. Wasserman, L. Renzetti, P. Paciorek, 1996, American journal of respiratory cell and molecular biology.

Ro 45-2081, a TNF receptor fusion protein, prevents inflammatory responses in the airways

L. Renzetti, P. R. Gater, 1997, Inflammation Research.

Transformation of human cells by a polyomavirus containing complementing JCV and RFV genomes.

L. Renzetti, F. O'Neill, T. Miller, 1988, Virus research.

Identification of N-acyl 4-(5-pyrimidine-2,4-dionyl)phenylalanine derivatives and their orally active prodrug esters as dual-acting alpha4-beta1 and alpha4-beta7 receptor antagonists.

A. Railkar, A. Sidduri, J. Lou, 2013, Bioorganic & medicinal chemistry letters.

Identification of N-acyl 4-(3-pyridonyl)phenylalanine derivatives and their orally active prodrug esters as dual acting α4β1 and α4β7 receptor antagonists.

A. Railkar, A. Sidduri, J. Lou, 2013, Bioorganic & medicinal chemistry letters.

Pharmacokinetics, Safety, and Tolerability of R411, a Dual α4β1‐α4β7 Integrin Antagonist After Oral Administration at Single and Multiple Once‐Daily Ascending Doses in Healthy Volunteers

R. Blain, Y. Hijazi, R. Abbas, 2004 .

Studies of the Combination of Ro 24–5913, a Peptidoleukotriene Antagonist, and Ro 24–4736, a PAF Antagonist, in Guinea pig and Rat Models of Lung Inflammation

J. Tocker, M. Wasserman, P. Newbold, 1994, Annals of the New York Academy of Sciences.

N-Aroyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.

R. Campbell, L. Chen, A. Sidduri, 2002, Bioorganic & medicinal chemistry letters.

Evaluation of the effect of multiple-dose administration of R411, a dual alpha4beta1-alpha4beta7 integrin antagonist on the major CYP isoform activities in healthy volunteers.

Y. Hijazi, I. Patel, K. Frank, 2006, European journal of clinical pharmacology.

Temperature dependency for maintenance of transformation in mouse cells transformed by simian virus 40 tsA mutants

S. Cohen, L. Renzetti, F. O'Neill, 1980, Journal of virology.

Evaluation of the effect of multiple-dose administration of R411, a dual α4β1–α4β7 integrin antagonist on the major CYP isoform activities in healthy volunteers

Y. Hijazi, I. Patel, K. Frank, 2005, European Journal of Clinical Pharmacology.

The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses.

L Adorini, L. Adorini, M. Gately, 1998, Annual review of immunology.

In vitro growth control phenotypes of transformed rodent cells prior to and following tumorigenesis.

L. Renzetti, F. O'Neill, 1983, Cancer research.

Contribution of intracellular calcium to gallbladder smooth muscle contraction.

J. Ryan, L. Renzetti, M. Wang, 1990, The American journal of physiology.

Discovery of 2,4-1H-Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors.

A. Keefe, G. Müller, L. Babiss, 2021, ACS medicinal chemistry letters.

Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response

Stephen T Holgate, S. Holgate, P. Barnes, 2000, The Lancet.

Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia

M. Foley, A. Stamford, M. Carroll, 2022, Cancer Discovery.