P. Augustijns

发表

Novel generic UPLC/MS/MS method for high throughput analysis applied to permeability assessment in early Drug Discovery.

Jef Adriaensen, Claire Mackie, M. Brewster, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Evaluation of various PAMPA models to identify the most discriminating method for the prediction of BBB permeability.

G. Verreck, M. Brewster, J. Mensch, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research

L. Marciani, H. Lennernäs, W. Weitschies, 2022, Pharmaceutics.

Biopredictive in vitro testing methods to assess intestinal drug absorption from supersaturating dosage forms

B. Hens, K. Kawakami, M. Kataoka, 2020 .

Stereoselective Pharmacokinetic Properties of Chloroquine and De-Ethyl-Chloroquine in Humans

P. Augustijns, N. Verbeke, 1993, Clinical pharmacokinetics.

High‐speed digital imaging method for ciliary beat frequency measurement

Frederik Maes, F. Maes, M. Brewster, 2005, The Journal of pharmacy and pharmacology.

Solvent systems and their selection in pharmaceutics and biopharmaceutics

M. Brewster, P. Augustijns, 2007 .

Supersaturating drug delivery systems: fast is not necessarily good enough.

M. Brewster, Marcus E Brewster, Patrick Augustijns, 2012, Journal of pharmaceutical sciences.

Preclinical and Clinical Studies

G. Verreck, M. Brewster, J. Brouwers, 2015 .

Usefulness of a novel Caco-2 cell perfusion system. I. In vitro prediction of the absorption potential of passively diffused compounds.

Bart Willems, M. Brewster, J. Mensch, 2004, Journal of pharmaceutical sciences.

Classification of the Crystallization Behavior of Amorphous Active Pharmaceutical Ingredients in Aqueous Environments

L. S. Taylor, Shweta A. Raina, P. Augustijns, 2013, Pharmaceutical Research.

In Vivo Assessment of Intestinal, Hepatic, and Pulmonary First Pass Metabolism of Propofol in the Rat

Araz A. Raoof, A. Raoof, R. Verbeeck, 1996, Pharmaceutical Research.

Application of PAMPA-models to predict BBB permeability including efflux ratio, plasma protein binding and physicochemical parameters.

Claire Mackie, Geert Verreck, G. Verreck, 2010, International journal of pharmaceutics.

The impact of advanced age on gastrointestinal characteristics that are relevant to oral drug absorption: An AGePOP review.

Cordula Stillhart, W. Weitschies, C. Matthys, 2023, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Application of PAMPA-models to predict BBB permeability including efflux ratio, plasma protein binding and physicochemical parameters.

Claire Mackie, Geert Verreck, G. Verreck, 2010, International journal of pharmaceutics.

Physicochemical characterization of solid dispersions of the antiviral agent UC-781 with polyethylene glycol 6000 and Gelucire 44/14.

L. Naesens, J. Balzarini, P. Augustijns, 2000, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Physical stabilisation of amorphous ketoconazole in solid dispersions with polyvinylpyrrolidone K25.

P Augustijns, R. Busson, P. Augustijns, 2001, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Improvement of the dissolution rate of artemisinin by means of supercritical fluid technology and solid dispersions.

P. Augustijns, G. Van den Mooter, N. Blaton, 2003, International journal of pharmaceutics.

Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1

Zhiwei Ye, Patrick Augustijns, Bruno Stieger, 2010, Xenobiotica; the fate of foreign compounds in biological systems.

CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells.

M. A. Moseley, P. Augustijns, D. Thakker, 1996, Drug metabolism and disposition: the biological fate of chemicals.

Screening of Tanzanian plant extracts for their potential inhibitory effect on P‐glycoprotein mediated efﬂux

P. D. de Witte, P. Augustijns, S. Deferme, 2003, Phytotherapy research : PTR.

Six years of progress in the oral biopharmaceutics area - a summary from the IMI OrBiTo project.

H Lennernäs, A Lindahl, E Sjögren, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

The Dynamic Intestinal Absorption Model (Diamod®), an in vitro tool to study the interconnected kinetics of gastrointestinal solubility, supersaturation, precipitation, and intestinal permeation processes of oral drugs

M. Marzorati, F. Moens, P. Augustijns, 2023, International journal of pharmaceutics: X.

Intestinal absorption characteristics of the low solubility thiocarboxanilide UC-781.

E. De Clercq, L. Naesens, J. Balzarini, 2002, International journal of pharmaceutics.

Effect of simulated intestinal fluid on drug permeability estimation across Caco-2 monolayers.

P Augustijns, B. Beck, P. Augustijns, 2004, International journal of pharmaceutics.

Potential of amorphous microporous silica for ibuprofen controlled release.

L. Froyen, J. Humbeeck, J. van Humbeeck, 2010, International journal of pharmaceutics.

Characterization of physico-chemical properties and pharmaceutical performance of sucrose co-freeze-dried solid nanoparticulate powders of the anti-HIV agent loviride prepared by media milling.

P Augustijns, L. Froyen, M. Brewster, 2007, International journal of pharmaceutics.

Inulin hydrogels as carriers for colonic drug targeting. Rheological characterization of the hydrogel formation and the hydrogel network.

L. Vervoort, P. Moldenaers, P. Augustijns, 1999, Journal of pharmaceutical sciences.

Chloroquine levels in blood during chronic treatment of patients with rheumatoid arthritis

P. Geusens, P. Augustijns, P. Augustijns, 1992, European Journal of Clinical Pharmacology.

Introduction to the OrBiTo decision tree to select the most appropriate in vitro methodology for release testing of solid oral dosage forms during development.

B Abrahamsson, P Augustijns, J Dressman, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Stable ciliary activity in human nasal epithelial cells grown in a perfusion system.

M. Brewster, M. Noppe, P. Augustijns, 2005, International journal of pharmaceutics.

Usefulness of a novel Caco-2 cell perfusion system II. Characterization of monolayer properties and peptidase activity.

M. Brewster, J. Mensch, M. Noppe, 2009, Die Pharmazie.

The use of human nasal in vitro cell systems during drug discovery and development.

M. Brewster, M. Noppe, P. Augustijns, 2005, Toxicology in vitro : an international journal published in association with BIBRA.

Simulated intestinal fluid as transport medium in the Caco-2 cell culture model.

P Augustijns, P. Augustijns, G. Van den Mooter, 2002, International journal of pharmaceutics.

Postprandial evolution in composition and characteristics of human duodenal fluids in different nutritional states.

P Augustijns, C Reppas, F. Lammert, 2009, Journal of pharmaceutical sciences.

Solubilizing agents in nasal formulations and their effect on ciliary beat frequency.

A. Bernkop‐Schnürch, P. Augustijns, P. Augustijns, 2012, Toxicology in vitro : an international journal published in association with BIBRA.

Effect of preservatives on ciliary beat frequency in human nasal epithelial cell culture: single versus multiple exposure.

P. Augustijns, P. Augustijns, R. Mallants, 2007, International journal of pharmaceutics.