Xiaofang Wang

发表

Conformational Studies of Glucose Transporter 1 (GLUT1) as an Anticancer Drug Target

S. Almahmoud, Xiaofang Wang, J. Vennerstrom, 2019, Molecules.

Antiprotozoal Selectivity of Diimidazoline N-Phenylbenzamides.

M. Kaiser, Yuxiang Dong, Xiaofang Wang, 2015, ACS infectious diseases.

Activity of diimidazoline amides against African trypanosomiasis.

M. Kaiser, Yuxiang Dong, Xiaofang Wang, 2014, Bioorganic & medicinal chemistry letters.

Effect of ozonide OZ418 against Schistosoma japonicum harbored in mice

S. Xiao, J. Xue, Yuxiang Dong, 2014, Parasitology Research.

In Vivo Activity of Aryl Ozonides against Schistosoma Species

J. Keiser, J. Chollet, Yuxiang Dong, 2011, Antimicrobial Agents and Chemotherapy.

Treatment of a chemoresistant neuroblastoma cell line with the antimalarial ozonide OZ513

S. Joshi, D. Coulter, J. Sharp, 2016, BMC Cancer.

Dual responsive micelles capable of modulating miRNA-34a to combat taxane resistance in prostate cancer.

R. Mahato, Xiaofang Wang, Feng Lin, 2019, Biomaterials.

Weak base dispiro-1,2,4-trioxolanes: potent antimalarial ozonides.

J. Karle, J. Chollet, S. Charman, 2007, Bioorganic & medicinal chemistry letters.

Structure-Activity Relationship of the Antimalarial Ozonide Artefenomel (OZ439).

David M. Shackleford, J. Chollet, S. Charman, 2017, Journal of medicinal chemistry.

Spiroadamantyl 1,2,4-trioxolane, 1,2,4-trioxane, and 1,2,4-trioxepane pairs: relationship between peroxide bond iron(II) reactivity, heme alkylation efficiency, and antimalarial activity.

J. K. Wood, J. Chollet, S. Charman, 2009, Bioorganic & medicinal chemistry letters.

Antischistosomal versus antiandrogenic properties of aryl hydantoin Ro 13-3978.

J. Keiser, R. Guy, Jaeki Min, 2014, The American journal of tropical medicine and hygiene.

Clinically Available Medicines Demonstrating Anti-Toxoplasma Activity

P. Davis, Xiaofang Wang, J. Vennerstrom, 2015, Antimicrobial Agents and Chemotherapy.

Spiro- and dispiro-1,2-dioxolanes: contribution of iron(II)-mediated one-electron vs two-electron reduction to the activity of antimalarial peroxides.

J. Chollet, S. Charman, D. Creek, 2007, Journal of medicinal chemistry.

Dispiro-1,2,4-trioxane analogues of a prototype dispiro-1,2,4-trioxolane: mechanistic comparators for artemisinin in the context of reaction pathways with iron(II).

J. K. Wood, James K. Wood, Yuxiang Dong, 2005, The Journal of organic chemistry.

The activity of dispiro peroxides against Fasciola hepatica.

J. Keiser, Qingjie Zhao, Yuxiang Dong, 2011, Bioorganic & medicinal chemistry letters.

Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes.

J. Karle, J. Chollet, S. Charman, 2005, Journal of medicinal chemistry.

Identification and biological evaluation of natural product Biochanin A.

Xiaofang Wang, Quanxiang Han, Junqi Liu, 2020, Bioorganic chemistry.

Synthesis, Structure, White-Light Emission, and Temperature Recognition Properties of Eu/Tb Mixed Coordination Polymers.

H Zhao, Huaiming Hu, G. Xue, 2016, Inorganic chemistry.

Synthesis of 2-Azaadamantan-6-one: A Missing Isomer

Yuxiang Dong, Xiaofang Wang, J. Vennerstrom, 2018, ACS omega.

The structure-activity relationship of the antimalarial ozonide arterolane (OZ277).

J. Chollet, S. Charman, W. Charman, 2010, Journal of medicinal chemistry.

Comparative antimalarial activities and ADME profiles of ozonides (1,2,4-trioxolanes) OZ277, OZ439, and their 1,2-dioxolane, 1,2,4-trioxane, and 1,2,4,5-tetraoxane isosteres.

J. Chollet, S. Charman, E. Ryan, 2013, Journal of medicinal chemistry.

Tricyclic Imidazolidin-4-ones by Witkop Oxidation of Tetrahydro-β-carbolines.

J. Garrison, Yuxiang Dong, Xiaofang Wang, 2020, The Journal of organic chemistry.

Antischistosomal Tetrahydro-γ-carboline Sulfonamides.

J. Keiser, M. Kaiser, Yuxiang Dong, 2022, Bioorganic & medicinal chemistry letters.

Review of Experimental Compounds Demonstrating Anti-Toxoplasma Activity

P. Davis, Xiaofang Wang, J. Vennerstrom, 2016, Antimicrobial Agents and Chemotherapy.

Structure-activity relationship of an ozonide carboxylic acid (OZ78) against Fasciola hepatica.

J. Keiser, Qingjie Zhao, Yuxiang Dong, 2010, Journal of medicinal chemistry.

Inhibition of Cytomegalovirus Replication with Extended-Half-Life Synthetic Ozonides

S. Charman, Xiaofang Wang, J. Vennerstrom, 2018, Antimicrobial Agents and Chemotherapy.

Semipinacol and protoadamantane-adamantane rearrangements of 5,6-dibromoadamantan-2-one and -2-ol

J. K. Wood, James K. Wood, J. Garrison, 2017 .

Peroxide Bond-Dependent Antiplasmodial Specificity of Artemisinin and OZ277 (RBx11160)

R. Brun, H. Matile, M. Kaiser, 2007, Antimicrobial Agents and Chemotherapy.

Effect of ozonide OZ418 against Schistosoma japonicum harbored in mice

S. Xiao, J. Xue, Yuxiang Dong, 2014, Parasitology Research.

Amino ozonides exhibit in vitro activity against Echinococcus multilocularis metacestodes.

J. Keiser, A. Hemphill, Yuxiang Dong, 2014, International journal of antimicrobial agents.

In Vitro and In Vivo Antischistosomal Activity Profiling and Pharmacokinetics of Ozonide Carboxylic Acids.

J. Keiser, S. Charman, Xiaofang Wang, 2023, ACS infectious diseases.

Peroxide Antimalarial Drugs Target Redox Homeostasis in Plasmodium falciparum Infected Red Blood Cells

D. Creek, Dovile Anderson, G. Siddiqui, 2021, bioRxiv.

Small molecule mimics of DFTamP1, a database designed anti-Staphylococcal peptide.

Guangshun Wang, T. Lushnikova, Yuxiang Dong, 2017, Bioorganic & medicinal chemistry.

HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives.

R. Cheng, K. Kossen, S. Seiwert, 2009, Bioorganic & medicinal chemistry letters.

Monoclonal Antibodies That Recognize the Alkylation Signature of Antimalarial Ozonides OZ277 (Arterolane) and OZ439 (Artefenomel)

O. Biehlmaier, P. Mäser, H. Matile, 2015, ACS infectious diseases.

Ozonide antimalarials alkylate heme in the malaria parasite Plasmodium falciparum.

S. Charman, D. Creek, Dovile Anderson, 2019, ACS infectious diseases.

Structure-Activity Relationship of Antischistosomal Ozonide Carboxylic Acids.

David M. Shackleford, J. Keiser, S. Charman, 2020, Journal of medicinal chemistry.

A new chemotype with promise against Trypanosoma cruzi.

F. Buckner, P. Davis, G. Lepesheva, 2019, Bioorganic & medicinal chemistry letters.

Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439.

David M. Shackleford, S. Charman, Qingjie Zhao, 2021, ACS infectious diseases.

Stochastic protein alkylation by antimalarial peroxides.

Remo S. Schmidt, P. Mäser, H. Matile, 2019, ACS infectious diseases.

Characterization of the two major CYP450 metabolites of ozonide (1,2,4-trioxolane) OZ277.

A. Ruf, S. Charman, W. Charman, 2008, Bioorganic & medicinal chemistry letters.

Effect of functional group polarity on the antimalarial activity of spiro and dispiro-1,2,4-trioxolanes.

J. Chollet, S. Charman, W. Charman, 2006, Bioorganic & medicinal chemistry.

Ligand-based design of GLUT inhibitors as potential antitumor agents.

S. Almahmoud, Xiaofang Wang, J. Vennerstrom, 2020, Bioorganic & medicinal chemistry.

Design, synthesis and in vitro evaluation of phenylbenzamidine derivatives as SSRIs

Hui Wen, Xiaofang Wang, Fang Qin, 2007 .

Antischistosomal versus antiandrogenic properties of aryl hydantoin Ro 13-3978.

J. Keiser, Jaeki Min, Qingjie Zhao, 2014, The American journal of tropical medicine and hygiene.