A. Thike

发表

Evaluation of phospho-histone H3 in Asian triple-negative breast cancer using multiplex immunofluorescence

P. Tan, Bernett Lee, E. Lim, 2019, Breast Cancer Research and Treatment.

Clinical Significance of Mucin Extravasation in Breast Core Biopsy Specimens

P. Tan, J. T. Ho, J. Wong, 2011 .

Mucin extravasation in breast core biopsies – clinical significance and outcome correlation

A. Jara-Lazaro, P. Tan, G. Tse, 2009, Histopathology.

Y-box binding protein 1 is up-regulated in proliferative breast cancer and its inhibition deregulates the cell cycle.

P. Tan, B. Bay, M. Tsujimoto, 2010, International journal of oncology.

Predicting the likelihood of additional lymph node metastasis in sentinel lymph node positive breast cancer: validation of the Memorial Sloan-Kettering Cancer Centre (MSKCC) nomogram

P. Tan, B. Tan, G. Ho, 2013, Journal of Clinical Pathology.

A five-gene reverse transcription-PCR assay for pre-operative classification of breast fibroepithelial lesions

P. Tan, M. Tan, XiaoNa Wei, 2016, Breast Cancer Research.

Characteristics, behaviour and role of biomarkers in metastatic triple-negative breast cancer

P. Tan, H. Sasano, J. Yeong, 2019, Journal of Clinical Pathology.

Behaviour and characteristics of low‐grade ductal carcinoma in situ of the breast: literature review and single‐centre retrospective series

I. Ellis, P. Tan, B. Tan, 2019, Histopathology.

Expression of FGFR1 is an independent prognostic factor in triple-negative breast cancer

P. Tan, B. Bay, C. Cheng, 2015, Breast Cancer Research and Treatment.

Cancer-Testis Antigens in Triple-Negative Breast Cancer: Role and Potential Utility in Clinical Practice

P. Tan, J. Yeong, J. Iqbal, 2021, Cancers.

Medullary breast carcinoma: a pathogenic review and immunohistochemical study using tissue microarray

A. Jara-Lazaro, Ming Lee, A. Thike, 2021, Singapore medical journal.

Implications of the Updated 2013 American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations on Human Epidermal Growth Factor Receptor 2 Gene Testing Using Immunohistochemistry and Fluorescence In Situ Hybridization for Breast Cancer.

P. Tan, S. Tien, A. Thike, 2016, Archives of pathology & laboratory medicine.

Keratin 15, transcobalamin I and homeobox gene Hox-B13 expression in breast phyllodes tumors: novel markers in biological classification

P. Tan, B. Teh, P. Tan, 2012, Breast Cancer Research and Treatment.

Predictors of phyllodes tumours on core biopsy specimens of fibroepithelial neoplasms

A. Jara-Lazaro, P. Tan, G. Tse, 2010, Histopathology.

Hypoxia-regulated carbonic anhydrase IX (CAIX) protein is an independent prognostic indicator in triple negative breast cancer

P. Tan, Bernett Lee, J. Yeong, 2022, Breast Cancer Research.

Distant metastases in phyllodes tumours of the breast: an overview

P. Tan, A. Thike, V. Koh, 2017, Applied Cancer Research.

MED12 is frequently mutated in breast phyllodes tumours: a study of 112 cases

P. Tan, C. Ong, B. Teh, 2015, Journal of Clinical Pathology.

Paediatric fibroepithelial lesions revisited: pathological insights

P. Tan, A. Thike, K. Chang, 2015, Journal of Clinical Pathology.

Novel genetic aberrations in breast phyllodes tumours: comparison between prognostically distinct groups

P. Tan, B. Bay, M. Tan, 2014, Breast Cancer Research and Treatment.

Genomic landscapes of breast fibroepithelial tumors

Swe Swe Myint, P. Tan, Dachuan Huang, 2015, Nature Genetics.

MED12, TERT and RARA in fibroepithelial tumours of the breast

P. Tan, B. Teh, C. Ng, 2019, Journal of Clinical Pathology.

Stromal keratin expression in phyllodes tumours of the breast: a comparison with other spindle cell breast lesions

P. Tan, A. Thike, P. Cheok, 2012, Journal of Clinical Pathology.

ALDH1 expression is enriched in breast cancers arising in young women but does not predict outcome

P. Tan, E. Tan, A. Thike, 2013, British Journal of Cancer.

Expression of heparan sulfate in gastric carcinoma and its correlation with clinicopathological features and patient survival

P. Tan, B. Bay, S. Choo, 2010, Journal of Clinical Pathology.

Higher density of stromal M2 macrophages in breast ductal carcinoma in situ predicts recurrence

P. Tan, B. Bay, A. Thike, 2020, Virchows Archiv.

Hormone receptor and c-ERBB2 status in distant metastatic and locally recurrent breast cancer. Pathologic correlations and clinical significance.

P. Tan, G. Tse, N. Wong, 2010, American journal of clinical pathology.

MED12 protein expression in breast fibroepithelial lesions: correlation with mutation status and oestrogen receptor expression

P. Tan, B. Teh, B. Bay, 2016, Journal of Clinical Pathology.

Second harmonic generation microscopy is a novel technique for differential diagnosis of breast fibroepithelial lesions

P. Tan, B. Bay, Hanry Yu, 2015, Journal of Clinical Pathology.

Intranuclear inclusions in epithelial cells of benign proliferative breast lesions

A. Jara-Lazaro, P. Tan, F. Petersson, 2011, Journal of Clinical Pathology.

Multiplex immunohistochemistry/immunofluorescence (mIHC/IF) for PD-L1 testing in triple-negative breast cancer: a translational assay compared with conventional IHC

Yong Cheng Poh, Zi Long Chow, P. Tan, 2020, Journal of Clinical Pathology.

A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers—Analytical validation and performance evaluation with clinical samples

P. Tan, B. Teh, M. Tan, 2022, Frontiers in Molecular Biosciences.

Ductal carcinoma in situ associated with triple negative invasive breast cancer: evidence for a precursor–product relationship

P. Tan, G. Tse, J. Iqbal, 2013, Journal of Clinical Pathology.

Tumor Infiltrating Lymphocytes in Multi-National Cohorts of Ductal Carcinoma In Situ (DCIS) of Breast

P. Tan, A. Harris, D. Generali, 2022, Cancers.

Wnt Signaling Promotes Breast Cancer by Blocking ITCH-Mediated Degradation of YAP/TAZ Transcriptional Coactivator WBP2.

P. Tan, Zilin Li, T. Putti, 2016, Cancer research.

Utility of the Singapore nomogram for predicting recurrence-free survival in Japanese women with breast phyllodes tumours

P. Tan, N. Taira, M. Tan, 2014, Journal of Clinical Pathology.

MALT lymphoma and coincidental rectal carcinoma were found. Due to the paucity of data, a causal association between development of a gastric MALT lymph-

P. Tan, N. Taira, M. Tan, 2014 .

Histiocytoid breast carcinoma: an enigmatic lobular entity

P. Tan, G. Tse, A. Thike, 2011, Journal of Clinical Pathology.

Size and heterologous elements predict metastases in malignant phyllodes tumours of the breast

P. Tan, B. Bay, G. Yip, 2018, Virchows Archiv.

Correlation of p27kip1 and Cyclin D1 Proteins with Growth Activity in Grade 1 Oral Squamous Cell Carcinoma in Myanmar: a Preliminary Study

M. Takagi, A. Myint, A. Thike, 2004 .

Y‐box binding protein 1 is correlated with lymph node metastasis in intestinal‐type gastric cancer

P. Tan, B. Bay, T. Lim, 2015, Histopathology.

High Densities of Tumor-Associated Plasma Cells Predict Improved Prognosis in Triple Negative Breast Cancer

P. Tan, T. Putti, Bernett Lee, 2018, Front. Immunol..

Clinicopathological significance of calreticulin in breast invasive ductal carcinoma

F. Chew, P. Tan, B. Bay, 2010, Modern Pathology.

Breast cancer in women with neurofibromatosis type 1 (NF1): a comprehensive case series with molecular insights into its aggressive phenotype

P. Tan, P. Munusamy, I. Tan, 2018, Breast Cancer Research and Treatment.

Epithelial–mesenchymal transition and cancer stem cell interactions in breast phyllodes tumours: immunohistochemical evaluation of EZH2, EZR, HMGA2, CD24 and CD44 in correlation with outcome analysis

P. Tan, J. Iqbal, J. Lim, 2021, Journal of Clinical Pathology.

Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2

Swe Swe Myint, P. Tan, Dachuan Huang, 2017, Science Translational Medicine.

DEAD-box helicase DP103 defines metastatic potential of human breast cancers.

C. Lim, M. Salto‐Tellez, P. Tan, 2014, The Journal of clinical investigation.

Identifying progression predictors of breast ductal carcinoma in situ

P. Tan, J. Yeong, J. Iqbal, 2016, Journal of Clinical Pathology.

Genetics and genomics of breast fibroadenomas

P. Tan, B. Teh, Cheok Soon Lee, 2017, Journal of Clinical Pathology.

Identification of Circulating MicroRNA Signatures for Breast Cancer Detection

P. Tan, G. Ho, C. Wong, 2013, Clinical Cancer Research.

TP53 Genomic Status Regulates Sensitivity of Gastric Cancer Cells to the Histone Methylation Inhibitor 3-Deazaneplanocin A (DZNep)

Qiang Yu, Na-Yu Chia, B. Bay, 2012, Clinical Cancer Research.

Predictive Biomarkers and Personalized Medicine TP 53 GenomicStatusRegulates Sensitivity of GastricCancer Cells to the HistoneMethylation Inhibitor 3-Deazaneplanocin A ( DZNep )

P. Tan, Qiang Yu, Na-Yu Chia, 2012 .

Clinicopathological significance of ARID1B in breast invasive ductal carcinoma

P. Tan, B. Bay, G. Baeg, 2015, Histopathology.

Whole‐exome sequencing of breast cancer, malignant peripheral nerve sheath tumor and neurofibroma from a patient with neurofibromatosis type 1

P. Tan, C. Ong, B. Teh, 2015, Cancer medicine.

Genetic differences between benign phyllodes tumors and fibroadenomas revealed through targeted next generation sequencing

P. Tan, B. Teh, B. Bay, 2021, Modern Pathology.

Genomic profile of breast sarcomas: a comparison with malignant phyllodes tumours

P. Tan, B. Teh, B. Tan, 2018, Breast Cancer Research and Treatment.

Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma

Swe Swe Myint, P. Tan, C. Ong, 2014, Nature Genetics.

A five-gene reverse transcription-PCR assay for pre-operative classification of breast fibroepithelial lesions

P. Tan, M. Tan, XiaoNa Wei, 2016, Breast Cancer Research.

Predicting clinical behaviour of breast phyllodes tumours: a nomogram based on histological criteria and surgical margins

P. Tan, M. Tan, I. Busmanis, 2011, Journal of Clinical Pathology.

Caveolin-1 expression as a prognostic marker in triple negative breast cancers of Asian women

P. Tan, Bernett Lee, Seigo Nakamura, 2017, Journal of Clinical Pathology.

Mutations in the epidermal growth factor receptor (EGFR) gene in triple negative breast cancer: possible implications for targeted therapy

P. Tan, B. Bay, G. Tse, 2011, Breast Cancer Research.

Phyllodes tumours of the breast: the role of CD34, vascular endothelial growth factor and β‐catenin in histological grading and clinical outcome

P. Tan, G. Tse, A. Thike, 2013, Histopathology.

Prognostic significance of phosphoglycerate dehydrogenase in breast cancer

P. Tan, R. Huang, B. Bay, 2021, Breast Cancer Research and Treatment.

KIF21A regulates breast cancer aggressiveness and is prognostic of patient survival and tumor recurrence

V. B. Yap, P. Tan, B. Bay, 2021, Breast Cancer Research and Treatment.

A multigene assay identifying distinct prognostic subtypes of clear cell renal cell carcinoma with differential response to tyrosine kinase inhibition.

P. Tan, Q. Ng, M. Tan, 2015, European urology.

Elevated WBP2 Expression in HER2-positive Breast Cancers Correlates with Sensitivity to Trastuzumab-based Neoadjuvant Therapy: A Retrospective and Multicentric Study

P. Tan, T. Putti, J. Arribas, 2018, Clinical Cancer Research.

Insulin growth factor receptor‐1 expression and loss of PTEN protein predict early recurrence in triple‐negative breast cancer

P. Tan, G. Tse, J. Iqbal, 2012, Histopathology.

PD-L1 expression is an unfavourable prognostic indicator in Asian renal cell carcinomas

P. Tan, B. Teh, R. Kanesvaran, 2020, Journal of Clinical Pathology.

Higher densities of Foxp3+ regulatory T cells are associated with better prognosis in triple-negative breast cancer

P. Tan, S. Wong, Bernett Lee, 2017, Breast Cancer Research and Treatment.

Increased ID4 expression, accompanied by mutant p53 accumulation and loss of BRCA1/2 proteins in triple‐negative breast cancer, adversely affects survival

P. Tan, J. Iqbal, A. Thike, 2016, Histopathology.

Role of epithelial–mesenchymal transition markers in triple-negative breast cancer

P. Tan, J. Iqbal, J. Lim, 2015, Breast Cancer Research and Treatment.

Clinicopathological characteristics of oestrogen receptor negative, progesterone receptor positive breast cancers: re-evaluating subsets within this group

P. Tan, J. Lim, A. Thike, 2016, Journal of Clinical Pathology.

Higher densities of tumour‐infiltrating lymphocytes and CD4+ T cells predict recurrence and progression of ductal carcinoma in situ of the breast

P. Tan, B. Bay, A. Thike, 2019, Histopathology.

Prognostic role of immune infiltrates in breast ductal carcinoma in situ

P. Tan, B. Bay, J. Yeong, 2019, Breast Cancer Research and Treatment.

Loss of androgen receptor expression predicts early recurrence in triple-negative and basal-like breast cancer

Puay Hoon Tan, Boon Huat Bay, P. Tan, 2014, Modern Pathology.

Prognostic significance of epithelial–mesenchymal transition proteins Twist and Foxc2 in phyllodes tumours of the breast

P. Tan, J. Lim, A. Thike, 2015, Breast Cancer Research and Treatment.

Triple-negative breast cancer: clinicopathological characteristics and relationship with basal-like breast cancer

A. Jara-Lazaro, P. Tan, B. Tan, 2010, Modern Pathology.

Delineating the breast cancer immune microenvironment in the era of multiplex immunohistochemistry/immunofluorescence

P. Tan, J. Yeong, J. Lim, 2021, Histopathology.

IMMUNOHISTOCHEMICAL EXPRESSION OF HORMONE RECEPTORS IN INVASIVE BREAST CARCINOMA: CORRELATION OF RESULTS OF H‐SCORE WITH PATHOLOGICAL PARAMETERS

P. Tan, S. Fook-Chong, A. Thike, 2001, Pathology.

Predictive Factors for BRCA1 and BRCA2 Genetic Testing in an Asian Clinic-Based Population

P. Tan, P. Ang, M. Tan, 2015, PloS one.

Cancer stem cell and epithelial–mesenchymal transition markers predict worse outcome in metaplastic carcinoma of the breast

P. Tan, A. Thike, S. Tan, 2015, Breast Cancer Research and Treatment.

Clinicopathologic Characteristics of Solid Papillary Carcinoma of the Breast

I. Ellis, P. Tan, A. Thike, 2016, The American journal of surgical pathology.

Increased CD4 and CD8-positive T cell infiltrate signifies good prognosis in a subset of triple-negative breast cancer

P. Tan, R. Dent, S. Koo, 2016, Breast Cancer Research and Treatment.

Therapeutic and immunomodulatory potential of pazopanib in malignant phyllodes tumor

P. Tan, B. Teh, Shun-Jie Li, 2022, npj Breast Cancer.

Predicting Breast Cancer Events in Ductal Carcinoma In Situ (DCIS) Using Generative Adversarial Network Augmented Deep Learning Model

P. Tan, A. Harris, Sanghee Cho, 2023, medRxiv.

Molecular insights into paediatric breast fibroepithelial tumours

P. Tan, B. Teh, C. Ng, 2018, Histopathology.

Prognostic value of CD8 + PD-1+ immune infiltrates and PDCD1 gene expression in triple negative breast cancer

P. Tan, Y. Yang, E. Newell, 2019, Journal of Immunotherapy for Cancer.

Breast sarcomas and malignant phyllodes tumours: comparison of clinicopathological features, treatment strategies, prognostic factors and outcomes

P. Tan, B. Tan, A. Thike, 2016, Breast Cancer Research and Treatment.

Breast carcinoma and phyllodes tumour: a case series

P. Tan, B. Tan, C. Wong, 2015, Journal of Clinical Pathology.

Molecular classification of breast phyllodes tumors: validation of the histologic grading scheme and insights into malignant progression

P. Tan, K. Dykema, K. Furge, 2011, Breast Cancer Research and Treatment.

Morphologic and genetic heterogeneity in breast fibroepithelial lesions—a comprehensive mapping study

P. Tan, B. Teh, C. Ng, 2020, Modern Pathology.

Genomic characterisation of breast fibroepithelial lesions in an international cohort

P. Tan, B. Teh, B. Tan, 2019, The Journal of pathology.

Breast ductal Carcinoma in situ associated with microinvasion induces immunological response and predicts ipsilateral invasive recurrence

P. Tan, B. Bay, A. Thike, 2020, Virchows Archiv.

Characteristics and behaviour of screen-detected ductal carcinoma in situ of the breast: comparison with symptomatic patients

P. Tan, B. Tan, I. Busmanis, 2015, Breast Cancer Research and Treatment.

Prognostic significance of Claudin 12 in estrogen receptor-negative breast cancer

P. Tan, B. Bay, G. Yip, 2016, Journal of Clinical Pathology.

HER2/neu revisited: quality and interpretive issues

P. Tan, S. Tien, J. Iqbal, 2010, Journal of Clinical Pathology.

False negative rate for intraoperative sentinel lymph node frozen section in patients with breast cancer: a retrospective analysis of patients in a single Asian institution

P. Tan, B. Tan, G. Ho, 2015, Journal of Clinical Pathology.

p53-Independent regulation of p21Waf1/Cip1 expression and senescence by PRMT6

P. Tan, V. Kuznetsov, Nancy Jennifer, 2012, Nucleic acids research.

p 53-Independent regulation of p 21 Waf 1 / Cip 1 expression and senescence by PRMT 6

P. Tan, V. Kuznetsov, Nancy Jennifer, 2012 .

Assessment of suitability of the one step nucleic acid amplification (OSNA) assay as an intraoperative procedure for detection of metastasis in sentinel lymph nodes of breast cancer

A. Jara-Lazaro, P. Tan, B. Tan, 2014, Journal of Clinical Pathology.

Diagnostic issues in second opinion consultations in prostate pathology

A. Jara-Lazaro, P. Tan, A. Thike, 2010, Pathology.

Sentinel lymph nodes with isolated tumour cells and micrometastases in breast cancer: clinical relevance and prognostic significance

P. Tan, B. Tan, G. Ho, 2013, Journal of Clinical Pathology.

Second harmonic generation microscopy is a novel technique for differential diagnosis of breast fibroepithelial lesions

P. Tan, B. Bay, Hanry Yu, 2015, Journal of Clinical Pathology.

The role of Ki-67 in Asian triple negative breast cancers: a novel combinatory panel approach

P. Tan, Bernett Lee, E. Lim, 2019, Virchows Archiv.

Epigenetic derepression converts PPARγ into a druggable target in triple-negative and endocrine-resistant breast cancers

P. Tan, T. Tan, R. Huang, 2021, Cell death discovery.

Utility of mammaglobin and gross cystic disease fluid protein-15 (GCDFP-15) in confirming a breast origin for recurrent tumors.

P. Tan, A. Thike, P. Cheok, 2010, Breast.

CD117 expression in breast phyllodes tumors correlates with adverse pathologic parameters and reduced survival

P. Tan, B. Bay, M. Tan, 2015, Modern Pathology.

A novel genomic panel as an adjunctive diagnostic tool for the characterization and profiling of breast Fibroepithelial lesions

P. Tan, B. Teh, B. Tan, 2019, BMC medical genomics.

A genetic mutation panel for differentiating malignant phyllodes tumour from metaplastic breast carcinoma.

P. Tan, B. Teh, K. Loh, 2017, Pathology.

GRAM domain-containing protein 1B (GRAMD1B), a novel component of the JAK/STAT signaling pathway, functions in gastric carcinogenesis

P. Tan, G. Baeg, W. Wan, 2017, OncoTarget.

A novel genomic panel as an adjunctive diagnostic tool for the characterization and profiling of breast Fibroepithelial lesions

W. Liu, P. Tan, B. Teh, 2019, BMC Medical Genomics.

Artificial intelligence modelling in differentiating core biopsies of fibroadenoma from phyllodes tumor

P. Tan, C. Cheng, A. Thike, 2021, Laboratory Investigation.

Triple Negative Breast Cancer: Outcome Correlation With Immunohistochemical Detection of Basal Markers

P. Tan, G. Tse, P. Tan, 2010, The American journal of surgical pathology.

Immunohistochemical expression of homeoproteins Six1 and Pax3 in breast phyllodes tumours correlates with histological grade and clinical outcome

P. Tan, B. Bay, A. Thike, 2014, Histopathology.

Using computer assisted image analysis to determine the optimal Ki67 threshold for predicting outcome of invasive breast cancer

Zi Long Chow, A. Jara-Lazaro, P. Tan, 2018, Oncotarget.

Comparison of the sensitivity and specificity of p16/Ki-67 dual staining and HPV DNA testing of abnormal cervical cytology in the detection of histology proven cervical intraepithelial neoplasia grade 2 and above (CIN 2+).

A. Thike, J. S. Hwang, M. Hilmy, 2017, The Malaysian journal of pathology.

Quantitative stain-free imaging and digital profiling of collagen structure reveal diverse survival of triple negative breast cancer patients

Yong Cheng Poh, P. Tan, Weimiao Yu, 2020, Breast Cancer Research.

Triple-negative and HER2 positive ductal carcinoma in situ of the breast: characteristics, behavior, and biomarker profile

P. Tan, H. Sasano, Satoshi Takahashi, 2018, Virchows Archiv.

Therapeutic targets in triple negative breast cancer - where are we now?

P. Tan, N. Wong, A. Thike, 2011, Recent Patents on Anti-Cancer Drug Discovery.

Counting Mitoses With Digital Pathology in Breast Phyllodes Tumors.

Zi Long Chow, P. Tan, J. Yeong, 2020, Archives of pathology & laboratory medicine.

Syndecan-1 is a potential biomarker for triple-positive breast carcinomas in Asian women with correlation to survival.

A. Jara-Lazaro, P. Tan, G. Yip, 2014, Singapore medical journal.

The role of Ki-67 in Asian triple negative breast cancers: a novel combinatory panel approach

P. Tan, Bernett Lee, E. Lim, 2019, Virchows Archiv.

DEAD-box helicase DP103 defines metastatic potential of human breast cancers.

C. Lim, M. Salto‐Tellez, P. Tan, 2014, The Journal of clinical investigation.

Breast carcinoma and phyllodes tumour: a case series

P. Tan, C. Wong, V. Tan, 2015, Journal of Clinical Pathology.

J. Hwang, A. Thike, M. Hilmy, 2017, The Malaysian journal of pathology.