J. Zaro

发表

Cationic and amphipathic cell-penetrating peptides (CPPs): Their structures and in vivo studies in drug delivery

Wei-Chiang Shen, W. Shen, J. Zaro, 2015, Frontiers of Chemical Science and Engineering.

Cell Penetrating Peptides: Intracellular Pathways and Pharmaceutical Perspectives

Wei-Chiang Shen, W. Shen, J. Zaro, 2007, Pharmaceutical Research.

Comparison of cationic and amphipathic cell penetrating peptides for siRNA delivery and efficacy.

W. Shen, J. Zaro, Robert H Mo, 2012, Molecular pharmaceutics.

Tumor targeting of a cell penetrating peptide by fusing with a pH-sensitive histidine-glutamate co-oligopeptide.

P. Conti, W. Shen, Li-peng Yap, 2014, Biomaterials.

Evidence that membrane transduction of oligoarginine does not require vesicle formation.

W. Shen, J. Zaro, 2005, Experimental cell research.

Quantitative comparison of membrane transduction and endocytosis of oligopeptides.

W. Shen, J. Zaro, 2003, Biochemical and biophysical research communications.

Recombinant peptide constructs for targeted cell penetrating peptide-mediated delivery.

W. Shen, J. Zaro, Likun Fei, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Design of an in vivo cleavable disulfide linker in recombinant fusion proteins.

Wei-Chiang Shen, Yun Bai, W. Shen, 2010, BioTechniques.

Lipid-Based Drug Carriers for Prodrugs to Enhance Drug Delivery

J. Zaro, 2014, The AAPS Journal.

Membrane transduction of oligoarginine in HeLa cells is not mediated by macropinocytosis.

C. Okamoto, W. Shen, J. Zaro, 2006, Molecular pharmaceutics.

Proinsulin-Transferrin Fusion Protein Exhibits a Prolonged and Selective Effect on the Control of Hepatic Glucose Production in an Experimental Model of Type 1 Diabetes.

W. Shen, J. Zaro, J. Shao, 2016, Molecular Pharmaceutics.

Characterization of Polyelectrolyte Complex Formation Between Anionic and Cationic Poly(amino acids) and Their Potential Applications in pH-Dependent Drug Delivery

W. Shen, J. Zaro, Z. Folchman-Wagner, 2017, Molecules.

Tissue barriers and novel approaches to achieve hepatoselectivity of subcutaneously-injected insulin therapeutics

W. Shen, J. Zaro, J. Shao, 2016, Tissue barriers.

Interaction between Cell-Penetrating Peptides and Acid-Sensitive Anionic Oligopeptides as a Model for the Design of Targeted Drug Carriers

Jiasheng Tu, W. Shen, Chunmeng Sun, 2014, Molecular pharmaceutics.

Acid‐sensitive hybrid polymeric micelles containing a reversibly activatable cell‐penetrating peptide for tumor‐specific cytoplasm targeting

Yinglan Yu, Jiasheng Tu, W. Shen, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Vesicle-to-cytosol transport of disulfide-linked cargo mediated by an amphipathic cell-penetrating peptide

W. Shen, J. Zaro, Randall Kenien, 2012, Journal of drug targeting.

MAP-mediated nuclear delivery of a cargo protein

W. Shen, J. Zaro, Randall Kenien, 2012, Journal of drug targeting.

The influence of net charge and charge distribution on cellular uptake and cytosolic localization of arginine-rich peptides

L. Ren, W. Shen, J. Zaro, 2011, Journal of drug targeting.

Nuclear localization of cell-penetrating peptides is dependent on endocytosis rather than cytosolic delivery in CHO cells.

T. Tran, W. Shen, J. Zaro, 2009, Molecular pharmaceutics.

Cytosolic delivery of a p16-peptide oligoarginine conjugate for inhibiting proliferation of MCF7 cells.

W. Shen, J. Zaro, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Lipid-Based Carriers for Prodrugs to Enhance Delivery

Lawrence X. Yu, D. Lu, J. Zaro, 2015 .

Fusion protein linkers: property, design and functionality.

Wei-Chiang Shen, W. Shen, Xiaoying Chen, 2013, Advanced drug delivery reviews.

Advances in Exosome-Based Drug Delivery and Tumor Targeting: From Tissue Distribution to Intracellular Fate

J. Zaro, Yuxian Shen, J. Shao, 2020, International journal of nanomedicine.

Selective Intracellular Delivery of Recombinant Arginine Deiminase (ADI) Using pH-Sensitive Cell Penetrating Peptides To Overcome ADI Resistance in Hypoxic Breast Cancer Cells.

Yun-Ru Chen, Li-Jiuan Shen, D. Ann, 2016, Molecular pharmaceutics.

Effects of Lipofectamine 2000/siRNA Complexes on Autophagy in Hepatoma Cells

J. Ou, W. Shen, J. Zaro, 2012, Molecular Biotechnology.

pH-dependent reversibly activatable cell-penetrating peptides improve the antitumor effect of artemisinin-loaded liposomes.

Dongsheng He, Yinglan Yu, Jiasheng Tu, 2020, Journal of colloid and interface science.

Pharmacokinetics of recombinant bifunctional fusion proteins

W. Shen, J. Zaro, Xiaoying Chen, 2012, Expert opinion on drug metabolism & toxicology.

Characterization of transferrin receptor-mediated endocytosis and cellular iron delivery of recombinant human serum transferrin from rice (Oryza sativa L.)

S. Pettit, N. Huang, W. Shen, 2012, BMC Biotechnology.

Receptor-mediated activation of a proinsulin-transferrin fusion protein in hepatoma cells.

W. Shen, Yan Wang, J. Zaro, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Antibody-Drug Conjugates

R. A. Lipper, D. Crommelin, W. Shen, 2015, AAPS Advances in the Pharmaceutical Sciences Series.

Fatty acids as therapeutic auxiliaries for oral and parenteral formulations.

W. Shen, J. Zaro, Michael J. Hackett, 2013, Advanced drug delivery reviews.

Use of Microfluidics to Prepare Lipid-Based Nanocarriers

J. Zaro, Jiaqi Cheng, Samantha Marcotte, 2023, Pharmaceutics.

Fusion Protein Linkers: Effects on Production, Bioactivity, and Pharmacokinetics

W. Shen, J. Zaro, Xiaoying Chen, 2013 .

Effects of receptor binding on plasma half-life of bifunctional transferrin fusion proteins.

Wei-Chiang Shen, W. Shen, Xiaoying Chen, 2011, Molecular pharmaceutics.

Characterization and Oral Delivery of Proinsulin-Transferrin Fusion Protein Expressed Using ExpressTec

N. Huang, W. Shen, Deshui Zhang, 2018, International journal of molecular sciences.

Proinsulin-Transferrin Fusion Protein as a Novel Long-Acting Insulin Analog for the Inhibition of Hepatic Glucose Production

W. Shen, Yan Wang, J. Zaro, 2014, Diabetes.

Mylotarg: Revisiting Its Clinical Potential Post-Withdrawal

J. Zaro, 2015 .

Summary and Future Directions of ADCs

W. Shen, J. Zaro, Jeffery Wang, 2015 .

Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery.

C. Okamoto, W. Shen, J. Zaro, 2017, Biomaterials.

Proinsulin-Transferrin Fusion Protein as a Novel Long-acting Insulin Analogue for the Inhibition of Hepatic Glucose Production Running title: ProINS-Tf as a long-acting inhibitor of HGP

W. Shen, Yan Wang, J. Zaro, 2013 .

Lipid-Based Drug Carriers for Prodrugs to Enhance Drug Delivery

J. Zaro, 2014, The AAPS Journal.

Enhanced insulin receptor interaction by a bifunctional insulin-transferrin fusion protein: an approach to overcome insulin resistance

W. Shen, J. Zaro, J. Shao, 2020, Scientific Reports.

Design of an in vivo cleavable disulfide linker in recombinant fusion proteins.

Yun Bai, W. Shen, J. Zaro, 2010, BioTechniques.

Nuclear localization of cell-penetrating peptides is dependent on endocytosis rather than cytosolic delivery in CHO cells.

T. Tran, W. Shen, J. Zaro, 2009, Molecular Pharmaceutics.