Liangxing Wu

发表

Fluorescent cassettes for monitoring three-component interactions in vitro and in living cells.

K. Burgess, R. Burghardt, A. Loudet, 2009, Journal of the American Chemical Society.

A new synthesis of symmetric boraindacene (BODIPY) dyes.

K. Burgess, Liangxing Wu, 2008, Chemical communications.

Synthesis and spectroscopic properties of rosamines with cyclic amine substituents.

K. Burgess, Liangxing Wu, 2008, The Journal of organic chemistry.

Naturally Assembled Excimers in Xanthenes as Singular and Highly Efficient Laser Dyes in Liquid and Solid Media

K. Burgess, Á. Costela, I. García‐Moreno, 2013 .

Optical control of calcium affinity in a spiroamido-rhodamine based calcium chelator.

G. Marriott, Liangxing Wu, Yingrui Dai, 2011, Organic letters.

Syntheses of highly fluorescent GFP-chromophore analogues.

K. Burgess, Liangxing Wu, 2008, Journal of the American Chemical Society.

Inhibition of ALK2 with bicyclic pyridyllactams.

W. Yao, Yaoyu Chen, Liangxing Wu, 2021, Bioorganic & medicinal chemistry letters.

Discovery of 5,7-Dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-ones as Highly Selective CDK2 Inhibitors.

Yvonne Lo, M. Covington, S. Diamond, 2022, ACS medicinal chemistry letters.

Energy transfer cassettes in silica nanoparticles target intracellular organelles.

D. Son, K. Burgess, R. Burghardt, 2011, Organic & biomolecular chemistry.

Functionalized BF(2) Chelated Azadipyrromethene Dyes.

K. Burgess, R. Bandichhor, A. Loudet, 2008, Tetrahedron.

Discovery of Novel Pyrazolopyrimidines as Potent, Selective, and Orally Bioavailable Inhibitors of ALK2.

M. Covington, S. Diamond, S. Yeleswaram, 2022, ACS medicinal chemistry letters.

Rosamines Targeting the Cancer Oxidative Phosphorylation Pathway

K. Burgess, L. Kiew, Hong-Boon Lee, 2014, PloS one.

New cytotoxic rosamine derivatives selectively accumulate in the mitochondria of cancer cells

K. Burgess, Hong-Boon Lee, Liangxing Wu, 2009, Anti-cancer drugs.

INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models

R. Wynn, H. Koblish, Yue Zhang, 2020, PLoS ONE.

Fluorescent amino- and thiopyronin dyes.

K. Burgess, Liangxing Wu, 2008, Organic letters.

Discovery of Pemigatinib: A Potent and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor.

R. Wynn, H. Koblish, Yue Zhang, 2021, Journal of medicinal chemistry.

Abstract 531: Activity of the selective FGFR 1, 2 and 3 inhibitor INCB054828 in genetically-defined models of triple-negative breast cancer

J. Pietenpol, B. Lehmann, P. Scherle, 2017 .

Abstract 1234: The novel FGFR4-selective inhibitor INCB062079 is efficacious in models of hepatocellular carcinoma harboring FGF19 amplification

X. Wen, M. Stubbs, P. Scherle, 2017 .

Abstract 4712: Discovery of INCB059872, a novel FAD-directed LSD1 inhibitor that is effective in preclinical models of human and murine AML

R. Wynn, A. Margulis, X. Liu, 2016 .

Abstract 1162: The evaluation of INCB059872, an FAD-directed covalent inhibitor of LSD1, in preclinical models of Ewing sarcoma

R. Wynn, X. Liu, P. Scherle, 2017 .

Abstract 2032: Combination of epigenetic regulation via LSD1 inhibition with signal transduction inhibitors significantly enhances anti-tumor activity in models of hematologic malignancies

R. Wynn, H. Koblish, X. Wen, 2017 .

Organelle-selective energy transfer: a fluorescent indicator of intracellular environment.

K. Burgess, R. Burghardt, A. Loudet, 2011, Bioorganic & medicinal chemistry letters.

Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor

R. Wynn, Yue Zhang, H. Koblish, 2022, Cancer discovery.

A new synthesis of symmetric boraindacene (BODIPY) dyes.

K. Burgess, Liangxing Wu, 2008, Chemical communications.