Ling-Wei Li

发表

Design, Synthesis, and Bioevaluation of Novel Enzyme-Triggerable Cell Penetrating Peptide-Based Dendrimers for Targeted Delivery of Camptothecin and Cancer Therapy.

Ruiyao Mai, Bulian Deng, Huiting Zhao, 2022, Journal of medicinal chemistry.

Structure-guided development of purine amide, hydroxamate, and amidoxime for the inhibition of non-small cell lung cancer.

Chi‐Huey Wong, Szu-Hua Pan, Jim-Min Fang, 2019, European journal of medicinal chemistry.

Novel CRBN-Recruiting Proteolysis-Targeting Chimeras as Degraders of Stimulator of Interferon Genes with In Vivo Anti-Inflammatory Efficacy.

Ruiyao Mai, Bulian Deng, Huiting Zhao, 2022, Journal of medicinal chemistry.

Discovery of novel 3-hydroxyandrosta-5,7-Diene-17-Carboxylic acid derivatives as anti-inflammatory bowel diseases (IBD) agents.

Jingxuan Chen, Wei Li, A. Slominski, 2021, European journal of medicinal chemistry.

Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.

Shuwen Liu, M. Luo, Ling-Wei Li, 2020, European journal of medicinal chemistry.

Recent progress in histone methyltransferase (G9a) inhibitors as anticancer agents.

Guochao Liao, Bin Yu, Ling-Wei Li, 2019, European journal of medicinal chemistry.

Discovery of novel cell-penetrating and tumor-targeting peptide-drug conjugate (PDC) for programmable delivery of paclitaxel and cancer treatment.

Chenyu Zhang, Zhiqiang Yu, Ruiyao Mai, 2020, European journal of medicinal chemistry.

Discovery of KRas G12C-IN-3 and Pomalidomide-based PROTACs as degraders of endogenous KRAS G12C with potent anticancer activity.

Jingxuan Chen, Zichao Yang, Huiting Zhao, 2021, Bioorganic chemistry.

Discovery of Novel Quinazoline-based KRAS G12C Inhibitors as Potential Anticancer Agents

Jingxuan Chen, Ruiyao Mai, Huiting Zhao, 2022, Bioorganic & Medicinal Chemistry.

Discovery of novel quinazoline-based covalent inhibitors of KRAS G12C with various cysteine-targeting warheads as potential anticancer agents.

Jingxuan Chen, Huiting Zhao, Ling-Wei Li, 2021, Bioorganic chemistry.

Discovery of Thieno[2,3-d]pyrimidine-based KRAS G12D inhibitors as potential anticancer agents via combinatorial virtual screening.

Zichao Yang, Ruiyao Mai, Bulian Deng, 2022, European journal of medicinal chemistry.

Efficient Synthesis and Bioevaluation of Novel Dual Tubulin/Histone Deacetylase 3 Inhibitors as Potential Anticancer Agents.

Jingxuan Chen, Ling-Wei Li, Jianjun Chen, 2021, Journal of medicinal chemistry.

Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death through Interaction with Katanin.

Chi‐Huey Wong, Hsuan-Yu Chen, Pan‐Chyr Yang, 2016, Journal of medicinal chemistry.

Design, synthesis, and biological evaluation of 1-substituted -2-aryl imidazoles targeting tubulin polymerization as potential anticancer agents.

Jingxuan Chen, Ling-Wei Li, Jianjun Chen, 2019, European journal of medicinal chemistry.

Discovery of novel 2-aryl-4-bis-amide imidazoles (ABAI) as anti-inflammatory agents for the treatment of inflammatory bowel diseases (IBD).

Jingxuan Chen, Huiting Zhao, Ling-Wei Li, 2022, Bioorganic chemistry.

Synthesis of N ‐Carbonyl Acridanes as Highly Potent Inhibitors of Tubulin Polymerization via One‐Pot Copper‐Catalyzed Dual Arylation of Nitriles with Cyclic Diphenyl Iodoniums

Ling-Wei Li, Jianjun Chen, Jin Liu, 2020, Advanced Synthesis & Catalysis.

Recent advances in trimethoxyphenyl (TMP) based tubulin inhibitors targeting the colchicine binding site.

Jing Su, Jing Su, Ling-Wei Li, 2018, European journal of medicinal chemistry.

Recent advances in peptide-based therapeutic strategies for breast cancer treatment

X. Ji, Xiaofang Luo, Wubliker Dessie, 2023, Frontiers in Pharmacology.

Design, synthesis and biological evaluation of novel acridine and quinoline derivatives as tubulin polymerization inhibitors with anticancer activities.

Ling-Wei Li, Yuyu Fang, Jianjun Chen, 2021, Bioorganic & medicinal chemistry.

Copper-Catalyzed Selective Arylation of Nitriles with Cyclic Diaryl Iodonium Salts: Direct Access to Structurally Diversified Diarylmethane Amides with Potential Neuroprotective and Anticancer Activities.

Jingxuan Chen, Ling-Wei Li, Jianjun Chen, 2020, Organic letters.

Discovery and Crystallography Study of Novel Biphenyl Ether and Oxadiazole Thioether (Non-Arylmethylamine)-Based Small-Molecule PD-1/PD-L1 Inhibitors as Immunotherapeutic Agents.

Ling-Wei Li, Jianjun Chen, Ting Liu, 2023, Journal of medicinal chemistry.

Discovery of Novel Histone Deacetylase 6 (HDAC6) Inhibitors with Enhanced Antitumor Immunity of Anti-PD-L1 Immunotherapy in Melanoma.

Jingxuan Chen, Ling-Wei Li, Jianjun Chen, 2022, Journal of medicinal chemistry.

Discovery of novel resorcinol biphenyl ether-based macrocyclic small molecules as PD-1/PD-L1 inhibitors with favorable pharmacokinetics for cancer immunotherapy.

Zichao Yang, Ling-Wei Li, Jianjun Chen, 2023, Bioorganic chemistry.