Jintang He

发表

Development of Efficient Chemistry to Generate Site-Specific Disulfide-Linked Protein- and Peptide-Payload Conjugates: Application to THIOMAB Antibody-Drug Conjugates.

Yanli Wang, J. Wai, Donglu Zhang, 2017, Bioconjugate chemistry.

Antibody-mediated delivery of chimeric protein degraders which target estrogen receptor alpha (ERα).

C. Li, R. Rowntree, BinQing Wei, 2019, Bioorganic & medicinal chemistry letters.

Identification and confirmation of biomarkers using an integrated platform for quantitative analysis of glycoproteins and their glycosylations.

Chen Li, J. Marrero, D. Lubman, 2010, Journal of proteome research.

Purification and Identification of Antioxidant Peptides from Enzymatic Hydrolysates of Tilapia (Oreochromis niloticus) Frame Protein

Liping Sun, Jintang He, Yongliang Zhuang, 2012, Molecules.

High-Resolution Accurate-Mass Mass Spectrometry Enabling In-Depth Characterization of in Vivo Biotransformations for Intact Antibody-Drug Conjugates.

Thomas H. Pillow, Geoffrey del Rosario, Jintang He, 2017, Analytical chemistry.

Serum autoantibody profiling using a natural glycoprotein microarray for the prognosis of early melanoma.

M. Sabel, Gang Su, D. Lubman, 2010, Journal of proteome research.

Comparative Studies of Early Liver Dysfunction in Senescence-accelerated Mouse Using Mitochondrial Proteomics Approaches*S

Lingyao Meng, Qingsong Wang, J. Ji, 2008, Molecular & Cellular Proteomics.

High-Resolution Characterization of ADCs by Orbitrap LCMS.

Jintang He, Keyang Xu, S. Kaur, 2020, Methods in molecular biology.

Characterization of in vivo biotransformations for trastuzumab emtansine by high-resolution accurate-mass mass spectrometry

S. Yee, Jintang He, Shang‐Fan Yu, 2018, mAbs.

Modulating Therapeutic Activity and Toxicity of Pyrrolobenzodiazepine Antibody–Drug Conjugates with Self-Immolative Disulfide Linkers

Jeffrey T. Lau, S. Spencer, P. Polakis, 2017, Molecular Cancer Therapeutics.

Chemical Structure and Concentration of Intratumor Catabolites Determine Efficacy of Antibody Drug Conjugates

P. Dragovich, C. Hop, H. Erickson, 2016, Drug Metabolism and Disposition.

A homogeneous high-DAR antibody–drug conjugate platform combining THIOMAB antibodies and XTEN polypeptides

R. Rowntree, A. Kamath, D. Reilly, 2021, Chemical science.

Antibody-Drug Conjugates Derived from Cytotoxic seco-CBI-Dimer Payloads Are Highly Efficacious in Xenograft Models and Form Protein Adducts In Vivo.

Jeffrey T. Lau, R. Rowntree, B. Vollmar, 2019, Bioconjugate chemistry.

Automated, generic reagent and ultra-targeted 2D-LC-MS/MS enabling quantification of biotherapeutics and soluble targets down to pg/mL range in serum.

Lingyao Meng, Jintang He, Keyang Xu, 2020, Analytical chemistry.

B lymphocytes as effector cells in the immunotherapy of cancer

A. Chang, D. Lubman, Shuang Wei, 2012, Journal of surgical oncology.

Modulating Antibody-Drug Conjugate Payload Metabolism by Conjugation Site and Linker Modification.

Yichin Liu, Ely Cosino, R. Vandlen, 2018, Bioconjugate chemistry.

The Identification of Novel Potential Injury Mechanisms and Candidate Biomarkers in Renal Allograft Rejection by Quantitative Proteomics*

Ronald J. Moore, Richard D. Smith, W. Xiao, 2013, Molecular & Cellular Proteomics.

The Identification of Novel Potential Injury Mechanisms and Candidate Biomarkers in Renal Allograft Rejection by Quantitative Proteomics.

Ronald J. Moore, Richard D. Smith, W. Xiao, 2014, Molecular & Cellular Proteomics.

Identification and confirmation of differentially expressed fucosylated glycoproteins in the serum of ovarian cancer patients using a lectin array and LC-MS/MS.

R. Buckanovich, D. Lubman, Jintang He, 2012, Journal of proteome research.

The Hippocampal Proteomic Analysis of Senescence-Accelerated Mouse: Implications of Uchl3 and Mitofilin in Cognitive Disorder and Mitochondria Dysfunction in SAMP8

Mingrui An, Qingsong Wang, J. Ji, 2008, Neurochemical Research.

Differential profiling studies of N‐linked glycoproteins in glioblastoma cancer stem cells upon treatment with γ‐secretase inhibitor

K. Muraszko, D. Lubman, Xing Fan, 2011, Proteomics.

Identification of cell surface glycoprotein markers for glioblastoma-derived stem-like cells using a lectin microarray and LC-MS/MS approach.

F. DiMeco, A. Vescovi, D. Lubman, 2010, Journal of proteome research.

Antibody‐independent targeted quantification of TMPRSS2‐ERG fusion protein products in prostate cancer

M. Rubin, A. Chinnaiyan, Naoki Kitabayashi, 2014, Molecular oncology.

Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics

M. Rubin, J. Mosquera, D. Camp, 2017, Journal of Translational Medicine.

Glycoproteomic analysis of glioblastoma stem cell differentiation.

F. DiMeco, A. Vescovi, D. Lubman, 2011, Journal of proteome research.

CD90 is Identified as a Candidate Marker for Cancer Stem Cells in Primary High-Grade Gliomas Using Tissue Microarrays*

F. DiMeco, K. Muraszko, A. Vescovi, 2011, Molecular & Cellular Proteomics.

Dose‐dependent proteomic analysis of glioblastoma cancer stem cells upon treatment with γ‐secretase inhibitor

S. Pennathur, D. Lubman, Xing Fan, 2011, Proteomics.

Purification and proteomic analysis of liver membrane skeletons.

Qingsong Wang, J. Ji, Jintang He, 2012, Methods in molecular biology.

A proteomics analysis of rat liver membrane skeletons: the investigation of actin- and cytokeratin-based protein components.

Lingyao Meng, Qingsong Wang, J. Ji, 2010, Journal of proteome research.

Clinical Utility of Serum Autoantibodies Detected by Protein Microarray in Melanoma

K. Griffith, M. Sabel, D. Lubman, 2011, International journal of proteomics.

Attachment Site Cysteine Thiol pKa Is a Key Driver for Site-Dependent Stability of THIOMAB Antibody-Drug Conjugates.

Genee Y. Lee, B. Vollmar, BinQing Wei, 2017, Bioconjugate chemistry.

Sensitive targeted quantification of ERK phosphorylation dynamics and stoichiometry in human cells without affinity enrichment.

Rui Zhao, Tao Liu, Marina A Gritsenko, 2015, Analytical chemistry.

Long-gradient separations coupled with selected reaction monitoring for highly sensitive, large scale targeted protein quantification in a single analysis.

Ronald J Moore, Sudhir Srivastava, Rui Zhao, 2013, Analytical chemistry.

Analytical platform evaluation for quantification of ERG in prostate cancer using protein and mRNA detection methods

Richard D. Smith, S. Srivastava, D. Camp, 2015, Journal of Translational Medicine.

Targeted quantification of low ng/mL level proteins in human serum without immunoaffinity depletion.

Ronald J. Moore, Richard D. Smith, D. Camp, 2013, Journal of proteome research.

Preclinical pharmacokinetics and pharmacodynamics of DCLL9718A: An antibody-drug conjugate for the treatment of acute myeloid leukemia

A. Kamath, Victor Yip, Jintang He, 2018, mAbs.

Decoupling stability and release in disulfide bonds with antibody-small molecule conjugates

J. Flygare, S. Bhakta, J. R. Junutula, 2016, Chemical science.

Mining the human urine proteome for monitoring renal transplant injury.

Richard D. Smith, M. Sarwal, D. Camp, 2016, Kidney international.

Expediting SRM Assay Development for Large-Scale Targeted Proteomics Experiments

Joseph N. Brown, Ronald J. Moore, Anil K. Shukla, 2014, Journal of proteome research.

Identification of glycoprotein markers for pancreatic cancer CD24+CD44+ stem-like cells using nano-LC-MS/MS and tissue microarray.

D. Simeone, D. Lubman, Jintang He, 2012, Journal of proteome research.

Immunohistochemical staining, laser capture microdissection, and filter‐aided sample preparation‐assisted proteomic analysis of target cell populations within tissue samples

K. Muraszko, J. Heth, S. Nie, 2013, Electrophoresis.

Proteomic analysis of a membrane skeleton fraction from human liver.

Qingsong Wang, J. Ji, Jintang He, 2007, Journal of proteome research.

Proteomic analysis and comparison of the biopsy and autopsy specimen of human brain temporal lobe

Wei Yang, Qingsong Wang, J. Ji, 2006, Proteomics.

Conjugation of Indoles to Antibodies through a Novel Self-Immolating Linker.

R. Rowntree, B. Vollmar, I. Wertz, 2018, Chemistry.

lity and release in disul fi de bonds with antibody-small molecule conjugates †

Geo., J. Flygare, S. Bhakta, 2016 .

Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics

Richard D. Smith, M. Rubin, J. Mosquera, 2017, Journal of Translational Medicine.

Comparison of two‐dimensional gel electrophoresis based and shotgun strategies in the study of plasma membrane proteome

Qingsong Wang, J. Ji, Jintang He, 2007, Proteomics. Clinical applications.

Analysis of glycoproteins for biomarker discovery.

Jing Wu, D. Lubman, Jintang He, 2013, Methods in molecular biology.

Characterization of membrane-associated glycoproteins using lectin affinity chromatography and mass spectrometry.

D. Lubman, Jintang He, Yashu Liu, 2013, Methods in molecular biology.