Bin Yang

发表

Synthesis and helical structure of lactam bridged BH3 peptides derived from pro-apoptotic Bcl-2 family proteins.

Ziwei Huang, Bin Yang, Dongxiang Liu, 2004, Bioorganic & medicinal chemistry letters.

Marine natural products with anti-HIV activities in the last decade.

Yonghong Liu, Xianwen Yang, Xiu-ping Lin, 2013, Current medicinal chemistry.

Identification and chemistry of C4H3 and C4H5 isomers in fuel-rich flames.

P. R. Westmoreland, James A. Miller, S. Klippenstein, 2006, The journal of physical chemistry. A.

Heteroarylamide smoothened inhibitors: Discovery of N-[2,4-dimethyl-5-(1-methylimidazol-4-yl)phenyl]-4-(2-pyridylmethoxy)benzamide (AZD8542) and N-[5-(1H-imidazol-2-yl)-2,4-dimethyl-phenyl]-4-(2- pyridylmethoxy)benzamide (AZD7254).

J. Janetka, A. Hird, L. Dakin, 2019, Bioorganic & medicinal chemistry.

Discovery of a Series of 7-Azaindoles as Potent and Highly Selective CDK9 Inhibitors for Transient Target Engagement.

A. Ferguson, L. Drew, W. Shao, 2021, Journal of medicinal chemistry.

Discovery of PROTAC molecules that selectively degrade the IRAK3 pseudokinase.

Fiona Pachl, O. Tavana, S. Degorce, 2020, Journal of medicinal chemistry.

Discovery of novel hedgehog antagonists from cell-based screening: Isosteric modification of p38 bisamides as potent inhibitors of SMO.

J. Janetka, A. Hird, L. Dakin, 2012, Bioorganic & medicinal chemistry letters.

Regulation of the Oligomeric Status of CCR3 with Binding Ligands Revealed by Single-Molecule Fluorescence Imaging.

Fang Huang, Baosheng Ge, Xiaojuan Wang, 2017, Biochemistry.

Angiogenesis , Metastasis , and the Cellular Microenvironment Inhibition of the Hedgehog Pathway Targets the Tumor-Associated Stroma in Pancreatic Cancer

R. Hwang, Jeffrey L. Brown, T. Moore, 2012 .

Optimization of Highly Kinase Selective Bis-anilino Pyrimidine PAK1 Inhibitors.

E. Hennessy, C. Chuaqui, A. Ferguson, 2016, ACS medicinal chemistry letters.

Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges.

Bin Yang, S. Edmondson, C. Fallan, 2019, Bioorganic & medicinal chemistry letters.

Small molecule inhibitor of apoptosis proteins antagonists: a patent review

E. Hennessy, B. Aquila, A. Hird, 2015, Expert opinion on therapeutic patents.

Synthesis, characterization, and anti-inflammatory activities of rare earth metal complexes of luteolin

Bin Yang, Lisheng Wang, Hua Yang, 2009, Medicinal Chemistry Research.

Cembrane Diterpenes Chemistry and Biological Properties

Yonghong Liu, Xianwen Yang, Xiu-ping Lin, 2012 .

Lutetium(III)-dependent self-assembly study of ciliate Euplotes octocarinatus centrin.

L. Duan, A. Liang, Bin Yang, 2008, Journal of inorganic biochemistry.

Diversified nanoparticle assembly pathways: materials architecture control beyond the amphiphilicity paradigm.

Bin Yang, Zhiqiang Lu, Sijing Xia, 2011, The journal of physical chemistry. B.

Single-Molecule Imaging Demonstrates Ligand Regulation of the Oligomeric Status of CXCR4 in Living Cells.

Fang Huang, Baosheng Ge, Xiaojuan Wang, 2017, The journal of physical chemistry. B.

Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies.

A. Ferguson, L. Drew, W. Shao, 2020, Journal of medicinal chemistry.

Identification and Optimization of Benzimidazole Sulfonamides as Orally Bioavailable Sphingosine 1-Phosphate Receptor 1 Antagonists with in Vivo Activity.

E. Hennessy, V. Oza, P. Lyne, 2015, Journal of medicinal chemistry.

Design, synthesis, and anti-allergic activities of novel (R)(-)-1-[(4-chlorophenyl)phenyl methyl]piperazine derivatives

Bin Yang, Lisheng Wang, Hua Yang, 2010, Medicinal Chemistry Research.

Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1.

C. Chuaqui, N. Keen, Nancy Su, 2013, ACS chemical biology.

Discovery of AZD9833, a potent and orally bioavailable selective estrogen receptor degrader and antagonist.

O. Delpuech, J. Breed, J. Nissink, 2020, Journal of medicinal chemistry.

Identification and optimisation of 7-azaindole PAK1 inhibitors with improved potency and kinase selectivity

E. Hennessy, C. Chuaqui, A. Ferguson, 2014 .

Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) Inhibitors.

J. Breed, P. Lyne, J. Janetka, 2018, Journal of Medicinal Chemistry.

Addition of Fluorine and a Late-Stage Functionalization (LSF) of the Oral SERD AZD9833.

Paul R. J. Davey, James S. Scott, B. Barlaam, 2020, ACS medicinal chemistry letters.

General methods for the synthesis and late-stage diversification of 2,4-substituted 7-azaindoles

Rebecca E. Meadows, B. Barlaam, Bryan E. Roberts, 2016 .

Building Bridges in a Series of Estrogen Receptor Degraders: An Application of Metathesis in Medicinal Chemistry.

J. Breed, J. Nissink, Paul R. J. Davey, 2019, ACS medicinal chemistry letters.

Discovery of potent KIFC1 inhibitors using a method of integrated high-throughput synthesis and screening.

E. Hennessy, C. Chuaqui, Nancy Su, 2014, Journal of medicinal chemistry.

Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-Antagonists.

J. Breed, J. Nissink, Paul R. J. Davey, 2023, Journal of medicinal chemistry.

Structure-based design and synthesis of tricyclic IAP (Inhibitors of Apoptosis Proteins) inhibitors.

E. Hennessy, B. Aquila, A. Hird, 2014, Bioorganic & medicinal chemistry letters.

A chemical strategy to promote helical peptide-protein interactions involved in apoptosis.

Ziwei Huang, R. Cao, Bin Yang, 2005, Bioorganic & medicinal chemistry letters.

Discovery of potent KIFC1 inhibitors using a method of integrated high-throughput synthesis and screening.

E. Hennessy, C. Chuaqui, Nancy Su, 2014, Journal of medicinal chemistry.

Synthesis and structure characterization of novel luteolin derivatives

Bin Yang, Jing Li, Li Wang, 2010, Chemistry of Natural Compounds.