S. D. de Kimpe

发表

Local dystrophin restoration with antisense oligonucleotide PRO051.

Johan T den Dunnen, G. van Ommen, J. D. den Dunnen, 2007, The New England journal of medicine.

FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection.

G. van Ommen, W. B. van den Berg, F. Hofhuis, 2002, Immunity.

Inhibition of IL-1 Signaling by Antisense Oligonucleotide-mediated Exon Skipping of IL-1 Receptor Accessory Protein (IL-1RAcP)

G. van Ommen, P. ’. ‘t Hoen, Annemieke Aartsma-Rus, 2013, Molecular therapy. Nucleic acids.

Albumin restores lysophosphatidylcholine-induced inhibition of vasodilation in rat aorta.

T. Rabelink, J. Joles, H. Koomans, 2001, Kidney international.

Vitamin E alleviates renal injury, but not hypertension, during chronic nitric oxide synthase inhibition in rats.

E. Stroes, A. Verhagen, J. Joles, 2001, Journal of the American Society of Nephrology : JASN.

The Dynamics of Compound, Transcript, and Protein Effects After Treatment With 2OMePS Antisense Oligonucleotides in mdx Mice

J. Ridings, Annemieke Aartsma-Rus, S. Hood, 2014, Molecular therapy. Nucleic acids.

Preclinical PK and PD Studies on 2′-O-Methyl-phosphorothioate RNA Antisense Oligonucleotides in the mdx Mouse Model

G. van Ommen, A. Ferlini, Annemieke Aartsma-Rus, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

In vivo comparison of 2′‐O‐methyl phosphorothioate and morpholino antisense oligonucleotides for Duchenne muscular dystrophy exon skipping

G. van Ommen, C. D. de Winter, J. V. van Deutekom, 2009, The journal of gene medicine.

Reversal of bradykinin-induced relaxation to contraction after interferon-gamma in bovine isolated mesenteric arteries.

F. Nijkamp, S. D. de Kimpe, D. van Heuven-Nolsen, 1994, European journal of pharmacology.

Opposite role of interferon-gamma and interleukin-4 on the regulation of blood pressure in mice.

I. van Ark, H. Savelkoul, A. V. van Oosterhout, 1999, Biochemical and biophysical research communications.

Antisense oligonucleotide mediated exon skipping as a potential strategy for the treatment of a variety of inflammatory diseases such as rheumatoid arthritis

G. van Ommen, P. ’. ‘t Hoen, J. V. van Deutekom, 2012, Annals of the rheumatic diseases.

Dose-dependent pharmacokinetic profiles of 2'-O-methyl phosphorothioate antisense oligonucleotidesin mdx mice.

J. V. van Deutekom, A. Aartsma-Rus, S. D. de Kimpe, 2013, Nucleic acid therapeutics.

Long-term Exon Skipping Studies With 2′-O-Methyl Phosphorothioate Antisense Oligonucleotides in Dystrophic Mouse Models

Annemieke Aartsma-Rus, J. V. van Deutekom, M. van Putten, 2012, Molecular therapy. Nucleic acids.

The Pharmacokinetics of 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides: Experiences from Developing Exon Skipping Therapies for Duchenne Muscular Dystrophy.

N. Datson, J. V. van Deutekom, S. Bosgra, 2019, Nucleic acid therapeutics.

Preclinical Studies on Intestinal Administration of Antisense Oligonucleotides as a Model for Oral Delivery for Treatment of Duchenne Muscular Dystrophy

K. V. van Dijk, Annemieke Aartsma-Rus, M. van Putten, 2014, Molecular therapy. Nucleic acids.

Systemic administration of PRO051 in Duchenne's muscular dystrophy.

G. van Ommen, Annemieke Aartsma-Rus, J. Verschuuren, 2011, The New England journal of medicine.

Guidelines for antisense oligonucleotide design and insight into splice-modulating mechanisms.

G. van Ommen, Annemieke Aartsma-Rus, C. D. de Winter, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy

B. Wieringa, D. Furling, T. M. Wheeler, 2009, Proceedings of the National Academy of Sciences.

The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure.

C. Thiemermann, J. Vane, S. D. de Kimpe, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages

Gert Folkerts, G. Folkerts, K. Karimi, 2006, Respiratory research.

Long-Term Efficacy, Safety, and Pharmacokinetics of Drisapersen in Duchenne Muscular Dystrophy: Results from an Open-Label Extension Study

N. Goemans, M. Van den Hauwe, J. V. van Deutekom, 2016, PloS one.

A Sensitive, Reproducible and Objective Immunofluorescence Analysis Method of Dystrophin in Individual Fibers in Samples from Patients with Duchenne Muscular Dystrophy

C. Beekman, J. V. van Deutekom, G. Campion, 2014, PloS one.

Bis(maltolato)oxovanadium(IV) Induces Angiogenesis via Phosphorylation of VEGFR2

P. Quax, M. D. de Vries, S. D. de Kimpe, 2020, International Journal of Molecular Sciences.

Mechanism of Gram-positive Shock: Identification of Peptidoglycan and Lipoteichoic Acid Moieties Essential in the Induction of Nitric Oxide Synthase, Shock, and Multiple Organ Failure

S. Foster, C. Thiemermann, S. D. de Kimpe, 1998, The Journal of experimental medicine.

Preclinical PK and PD Studies on 2'-O-Methyl-phosphorothioate RNA Antisense Oligonucleotides in the mdx Mouse Model.

G. van Ommen, A. Ferlini, Annemieke Aartsma-Rus, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Reactive oxygen species regulate macrophage scavenger receptor type I, but not type II, in the human monocytic cell line THP-1.

E. Anggard, M. Carrier, S. D. de Kimpe, 1998, Molecular pharmacology.

Placebo‐controlled Phase 2 Trial of Drisapersen for Duchenne Muscular Dystrophy

Ching H. Wang, B. Wong, A. Pestronk, 2018, Annals of clinical and translational neurology.

Evaluation of serum MMP-9 as predictive biomarker for antisense therapy in Duchenne

P. Nilsson, F. Muntoni, R. Wolterbeek, 2017, Scientific Reports.

Systemic administration of PRO051 in Duchenne's muscular dystrophy.

G. van Ommen, Annemieke Aartsma-Rus, J. Verschuuren, 2011, The New England journal of medicine.

Induction of nitric oxide release by interferon-gamma inhibits vasodilation and cyclic GMP increase in bovine isolated mesenteric arteries.

M. Radomski, F. Nijkamp, S. D. de Kimpe, 1994, The Journal of pharmacology and experimental therapeutics.