C. Smerdou

发表

Immunization with recombinant Semliki Forest virus induces protection against influenza challenge in mice.

P. Liljeström, P. Berglund, M. Fleeton, 1999, Vaccine.

Long-Term Systemic Expression of a Novel PD-1 Blocking Nanobody from an AAV Vector Provides Antitumor Activity without Toxicity

S. Hervás-Stubbs, G. González-Sapienza, N. Casares, 2020, Biomedicines.

Two-Helper RNA System for Production of Recombinant Semliki Forest Virus Particles

P. Liljeström, C. Smerdou, 1999, Journal of Virology.

Heme oxygenase-1 inducer hemin does not inhibit SARS-CoV-2 virus infection

M. Ávila, G. González-Aseguinolaza, A. Fontanellas, 2021, Biomedicine & Pharmacotherapy.

Replication and Packaging of Transmissible Gastroenteritis Coronavirus-Derived Synthetic Minigenomes

A. Izeta, S. Alonso, J. Plana-duran, 1999, Journal of Virology.

Optimization of a GDNF production method based on Semliki Forest virus vector.

E. Ansorena, E. Garbayo, M. Blanco-Prieto, 2021, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Capsid-deficient alphaviruses generate propagative infectious microvesicles at the plasma membrane

J. Prieto, N. Abrescia, C. Smerdou, 2016, Cellular and Molecular Life Sciences.

Virotherapy, gene transfer and immunostimulatory monoclonal antibodies

I. Melero, L. Álvarez-Vallina, P. Darcy, 2012, Oncoimmunology.

Enhancing immune responses using suicidal DNA vaccines

P. Liljeström, P. Berglund, M. Fleeton, 1998, Nature Biotechnology.

Increased efficacy and safety in the treatment of experimental liver cancer with a novel adenovirus-alphavirus hybrid vector.

J. Prieto, C. Qian, S. Kochanek, 2006, Cancer research.

Characterization of transmissible gastroenteritis coronavirus S protein expression products in avirulent S. typhimurium Δcya Δcrp: persistence, stability and immune response in swine

L. Enjuanes, C. Smerdou, A. Urniza, 1996, Veterinary Microbiology.

Residues involved in the antigenic sites of transmissible gastroenteritis coronavirus S glycoprotein

F. Gebauer, J. Lenstra, C. Sánchez, 1991, Virology.

Idiotype vaccines produced with a non-cytopathic alphavirus self-amplifying RNA vector induce antitumor responses in a murine model of B-cell lymphoma

C. Smerdou, Noelia Silva-Pilipich, E. Martišová, 2021, Scientific Reports.

Gene Therapy for Acquired and Genetic Cholestasis

G. González-Aseguinolaza, N. Weber, C. Smerdou, 2022, Biomedicines.

Adenovirus-Mediated Inducible Expression of a PD-L1 Blocking Antibody in Combination with Macrophage Depletion Improves Survival in a Mouse Model of Peritoneal Carcinomatosis

M. Buñuales, S. Hervás-Stubbs, S. Lumbreras, 2021, International journal of molecular sciences.

Eradication of Liver-Implanted Tumors by Semliki Forest Virus Expressing IL-12 Requires Efficient Long-Term Immune Responses

J. Prieto, P. Berraondo, S. Hervás-Stubbs, 2013, The Journal of Immunology.

Antigenic homology among coronaviruses related to transmissible gastroenteritis virus

F. Gebauer, M. Bullido, C. Sánchez, 1990, Virology.

Virotherapy with a Semliki Forest Virus–Based Vector Encoding IL12 Synergizes with PD-1/PD-L1 Blockade

I. Melero, V. Segura, E. Bolaños, 2015, Cancer Immunology Research.

Immunotherapeutic synergy between anti-CD137 mAb and intratumoral administration of a cytopathic Semliki Forest virus encoding IL-12.

I. Melero, S. Hervás-Stubbs, M. Sanmamed, 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

Semliki Forest Virus Expressing Interleukin-12 Induces Antiviral and Antitumoral Responses in Woodchucks with Chronic Viral Hepatitis and Hepatocellular Carcinoma

J. Prieto, G. González-Aseguinolaza, B. Tennant, 2009, Journal of Virology.

The immunological profile of tumor-bearing animals determines the outcome of cancer immunotherapy

S. Hervás-Stubbs, C. Smerdou, J. I. Quetglas, 2013, Oncoimmunology.

A Semliki Forest virus vector engineered to express IFNα induces efficient elimination of established tumors

J. Prieto, P. Berraondo, C. Smerdou, 2011, Gene Therapy.

A minimal bile salt excretory pump promoter allows bile acid-driven physiological regulation of transgene expression from a gene therapy vector

G. González-Aseguinolaza, C. Smerdou, L. Odriozola, 2022, Cell & bioscience.

Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus-Derived Vectors Fosters Dendritic Cell-Mediated T-cell Cross-Priming.

S. Quezada, I. Melero, M. Rodriguez-Ruiz, 2018, Cancer research.

Long noncoding RNA EGOT negatively affects the antiviral response and favors HCV replication

M. Enguita, P. Fortes, Marina Barriocanal, 2016, EMBO reports.

Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primates.

J. Prieto, I. Melero, S. Hervás-Stubbs, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

A new generation of vaccines based on alphavirus self-amplifying RNA

C. Smerdou, Noelia Silva-Pilipich, María Cristina Ballesteros-Briones, 2020, Current Opinion in Virology.

Non-viral amplification systems for gene transfer: vectors based on alphaviruses.

P. Liljeström, C. Smerdou, 1999, Current opinion in molecular therapeutics.

Rapid SARS-CoV-2 disinfection on distant surfaces with UV-C: The inactivation is affected by the type of material

F. Guillén-Grima, G. González-Aseguinolaza, S. Arana, 2022, Journal of Photochemistry and Photobiology.

A conserved coronavirus epitope, critical in virus neutralization, mimicked by internal-image monoclonal anti-idiotypic antibodies

L. Enjuanes, I. Antón, C. Smerdou, 1991, Journal of virology.

Biodistribution and tumor infectivity of semliki forest virus vectors in mice: effects of re-administration.

J. Prieto, C. Smerdou, J. R. Rodríguez-Madoz, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

The spike protein of transmissible gastroenteritis coronavirus controls the tropism of pseudorecombinant virions engineered using synthetic minigenomes.

C. Sánchez, A. Izeta, S. Alonso, 1998, Advances in experimental medicine and biology.

Galectin-3 inhibition boosts the therapeutic efficacy of Semliki Forest virus in pediatric osteosarcoma

A. Patiño-García, M. Alonso, M. Zalacain, 2022, Molecular therapy oncolytics.

Short-Term Local Expression of a PD-L1 Blocking Antibody from a Self-Replicating RNA Vector Induces Potent Antitumor Responses.

J. Prieto, I. Melero, M. Buñuales, 2019, Molecular therapy : the journal of the American Society of Gene Therapy.

A Proteomic Atlas of Lineage and Cancer-Polarized Expression Modules in Myeloid Cells Modeling Immunosuppressive Tumor-Infiltrating Subsets

M. Larsen, J. Fernández-Irigoyen, E. Santamaría, 2021, Journal of personalized medicine.

Development of Protection against Coronavirus Induced Diseases

J. Castilla, B. Pintado, I. Sola, 1995 .

Induction of an immune response to transmissible gastroenteritis coronavirus using vectors with enteric tropism.

J. Castilla, F. Graham, C. Sánchez, 1993, Advances in experimental medicine and biology.

Structure and encapsidation of transmissible gastroenteritis coronavirus (TGEV) defective interfering genomes.

F. Gebauer, A. Izeta, L. Enjuanes, 1995, Advances in experimental medicine and biology.

Strict requirement for vector-induced type I interferon in efficacious antitumor responses to virally encoded IL12.

I. Melero, S. Hervás-Stubbs, M. Sanmamed, 2015, Cancer research.

recombinant adenoviruses expressing virus antigens porcine transmissible gastroenteritis (TGEV) and their use in the formation of vaccines.

C. Sánchez, L. Enjuanes, J. Torres, 1995 .

Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer

Ibon Tamayo, S. Hervás-Stubbs, J. Lasarte, 2022, Frontiers in Immunology.

Cytokine gene transfer into dendritic cells for cancer treatment.

J. Prieto, C. Qian, I. Melero, 2002, Current gene therapy.

Vaccination with Recombinant Suicidal DNA/RNA

G. Atkins, I. Tubulekas, B. Sheahan, 1998 .

Development of protection against coronavirus induced diseases. A review.

J. Castilla, B. Pintado, I. Sola, 1995, Advances in experimental medicine and biology.

Photodynamic nasal SARS-CoV-2 decolonization shortens infectivity and influences specific T-Cell responses

A. Pineda-Lucena, Francesco P. Marchese, G. González-Aseguinolaza, 2023, Frontiers in Cellular and Infection Microbiology.

Evaluation of the Degradation of Materials by Exposure to Germicide UV-C Light Through Colorimetry, Tensile Strength and Surface Microstructure Analyses

F. Guillén-Grima, S. Arana, E. Pérez-Lorenzo, 2022, SSRN Electronic Journal.

PDL1 Signals through Conserved Sequence Motifs to Overcome Interferon-Mediated Cytotoxicity.

C. Wellbrock, I. Arozarena, K. Breckpot, 2017, Cell reports.

Molecular Characterization of Transmissible Gastroenteritis Coronavirus Defective Interfering Genomes: Packaging and Heterogeneity

F. Gebauer, A. Izeta, L. Enjuanes, 1996, Virology.

Alphavirus Vectors: Highly Efficient Systems for Transient Gene Expression

P. Liljeström, C. Smerdou, 2000 .

Location of antigenic sites of the S-glycoprotein of transmissible gastroenteritis virus and their conservation in coronaviruses.

F. Gebauer, M. Bullido, J. Lenstra, 1990, Advances in experimental medicine and biology.

Preclinical evaluation of a synthetic peptide vaccine against SARS-CoV-2 inducing multiepitopic and cross-reactive humoral neutralizing and cellular CD4 and CD8 responses

F. Prósper, G. González-Aseguinolaza, J. Lasarte, 2021, Emerging microbes & infections.

Antigen selection and presentation to protect against transmissible gastroenteritis coronavirus

F. Gebauer, C. Sánchez, L. Enjuanes, 1992, Veterinary Microbiology.

Gene therapy for progressive familial intrahepatic cholestasis type 3 in a clinically relevant mouse model

B. Bénichou, A. Douar, G. González-Aseguinolaza, 2019, Nature Communications.

A Simple and Efficient In Vivo Non-viral RNA Transfection Method for Labeling the Whole Axonal Tree of Individual Adult Long-Range Projection Neurons

T. Furuta, F. Clascá, César Porrero, 2016, Front. Neuroanat..

Gene therapy for HCV/HBV-induced hepatocellular carcinoma.

G. González-Aseguinolaza, C. Smerdou, R. Hernández-Alcoceba, 2010, Current opinion in investigational drugs.

Mechanisms of transmissible gastroenteritis coronavirus neutralization

F. Gebauer, M. Bullido, L. Enjuanes, 1990, Virology.

Alphavirus vectors for cancer therapy.

C. Smerdou, J. Bezunartea, Marta Ruiz-Guillen, 2010, Virus research.

Transcriptomic effects of Tet-on and mifepristone-inducible systems in mouse liver.

J. Prieto, C. Smerdou, J. de Las Rivas, 2008, Human gene therapy.

Intratumoral electroporation of a self-amplifying RNA expressing IL-12 induces antitumor effects in mouse models of cancer

J. Lasarte, C. Smerdou, Noelia Silva-Pilipich, 2022, Molecular therapy. Nucleic acids.

Neoadjuvant administration of Semliki Forest virus expressing interleukin-12 combined with attenuated Salmonella eradicates breast cancer metastasis and achieves long-term survival in immunocompetent mice

M. Moreno, J. Chabalgoity, C. Smerdou, 2015, BMC Cancer.

Semliki forest virus vectors engineered to express higher IL-12 levels induce efficient elimination of murine colon adenocarcinomas.

J. Prieto, C. Smerdou, J. R. Rodríguez-Madoz, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

Treatment with the senolytics dasatinib/quercetin reduces SARS‐CoV‐2‐related mortality in mice

M. Fresno, Andrés Pastor-Fernández, G. González-Aseguinolaza, 2023, Aging cell.

A continuous epitope from transmissible gastroenteritis virus S protein fused to E. coli heat-labile toxin B subunit expressed by attenuated Salmonella induces serum and secretory immunity

L. Enjuanes, R. Curtiss, I. Antón, 1996, Virus Research.

Gene therapy approaches against cancer using in vivo and ex vivo gene transfer of interleukin-12.

C. Smerdou, María Cristina Ballesteros-Briones, R. Hernández-Alcoceba, 2016, Immunotherapy.

A Small Virus to Deliver Small Antibodies: New Targeted Therapies Based on AAV Delivery of Nanobodies

C. Smerdou, Noelia Silva-Pilipich, L. Vanrell, 2021, Microorganisms.

A quick and efficient method to generate mammalian stable cell lines based on a novel inducible alphavirus DNA/RNA layered system

J. Prieto, E. Larrea, C. Smerdou, 2014, Cellular and Molecular Life Sciences.

A simple and efficient method for the production of human glycosylated glial cell line-derived neurotrophic factor using a Semliki Forest virus expression system.

E. Ansorena, E. Garbayo, M. Blanco-Prieto, 2013, International journal of pharmaceutics.

Recent patents on alphavirus protein expression and vector production.

C. Smerdou, J. Bezunartea, Marta Ruiz-Guillen, 2011, Recent patents on biotechnology.

A novel system for the production of high levels of functional human therapeutic proteins in stable cells with a Semliki Forest virus noncytopathic vector.

J. Prieto, C. Smerdou, Marta Ruiz-Guillen, 2010, New biotechnology.

Development of a new noncytopathic Semliki Forest virus vector providing high expression levels and stability.

J. Prieto, N. Razquin, C. Smerdou, 2008, Virology.

Induction of Antibodies Protecting against Transmissible Gastroenteritis Coronavirus (TGEV) by Recombinant Adenovirus Expressing TGEV Spike Protein

F. Graham, C. Sánchez, L. Enjuanes, 1995, Virology.

Complete Genome Sequence of Transmissible Gastroenteritis Coronavirus PUR46-MAD Clone and Evolution of the Purdue Virus Cluster

C. Sánchez, A. Izeta, I. Sola, 2004, Virus Genes.

Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses.

J. Lasarte, G. González-Sapienza, Ana Igea, 2023, Cancer letters.

479. Development and Characterization of a New Noncytopathic Vector Derived from Semliki Forest Virus

J. Prieto, N. Razquin, C. Smerdou, 2006 .

Alphavirus vectors: from protein production to gene therapy

P. Liljeström, C. Smerdou, 2000 .

JNK Activation in Alzheimer’s Disease Is Driven by Amyloid β and Is Associated with Tau Pathology

M. Luquin, M. Solas, I. Martínez-Valbuena, 2023, ACS chemical neuroscience.

Local Delivery of Immunomodulatory Antibodies for Gastrointestinal Tumors

C. Smerdou, Noelia Silva-Pilipich, Ángela Covo-Vergara, 2023, Cancers.

Short-term intratumoral interleukin-12 expressed from an alphaviral vector is sufficient to induce an efficient antitumoral response against spontaneous hepatocellular carcinomas.

J. Prieto, M. Zabala, C. Smerdou, 2014, Human gene therapy.

JNK3 Overexpression in the Entorhinal Cortex Impacts on the Hippocampus and Induces Cognitive Deficiencies and Tau Misfolding