J. Bylund

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The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor loop.

Tudor I. Oprea, T. Oprea, A. Karlsson, 2013, Biochimica et biophysica acta.

Amide Hydrolysis of a Novel Chemical Series of Microsomal Prostaglandin E Synthase-1 Inhibitors Induces Kidney Toxicity in the Rat

D. Hellgren, H. Andersson, J. Bylund, 2013, Drug Metabolism and Disposition.

TLR-Stimulated Neutrophils Instruct NK Cells To Trigger Dendritic Cell Maturation and Promote Adaptive T Cell Responses

J. Aurelius, A. Martner, K. Hellstrand, 2015, The Journal of Immunology.

A Bactericidal Cecropin-A Peptide with a Stabilized α-Helical Structure Possess an Increased Killing Capacity But No Proinflammatory Activity

C. Dahlgren, J. Bylund, H. Fu, 2004, Inflammation.

Human NK Cells Induce Neutrophil Apoptosis via an NKp46- and Fas-Dependent Mechanism

F. Thorén, Rebecca Riise, L. Moretta, 2012, The Journal of Immunology.

Exopolysaccharides from Burkholderia cenocepacia Inhibit Neutrophil Chemotaxis and Scavenge Reactive Oxygen Species*

R. Ernst, D. Speert, J. Bylund, 2006, Journal of Biological Chemistry.

Glycan analysis of human neutrophil granules implicates a maturation-dependent glycosylation machinery

N. Karlsson, Ian Loke, M. Thaysen‐Andersen, 2020, The Journal of Biological Chemistry.

Quantification of heterotypic granule fusion in human neutrophils by imaging flow cytometry

A. Karlsson, C. Dahlgren, J. Bylund, 2015, Data in brief.

Divergent Effects on Phagocytosis by Macrophage-Derived Oxygen Radicals

K. Brown, A. Karlsson, C. Dahlgren, 2009, Journal of Innate Immunity.

Increased intracellular oxygen radical production in neutrophils during febrile episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome.

D. Foell, K. Brown, A. Karlsson, 2013, Arthritis and rheumatism.

Increased intracellular oxygen radical production in neutrophils during febrile episodes of PFAPA syndrome

D. Foell, K. Brown, A. Karlsson, 2013 .

Subinhibitory Concentrations of the Deformylase Inhibitor Actinonin Increase Bacterial Release of Neutrophil-Activating Peptides: a New Approach to Antimicrobial Chemotherapy

C. Dahlgren, J. Bylund, H. Fu, 2003, Antimicrobial Agents and Chemotherapy.

Chemotherapy Peptides : a New Approach to Antimicrobial Bacterial Release of Neutrophil-Activating Deformylase Inhibitor Actinonin Increase Subinhibitory Concentrations of the

C. Dahlgren, J. Bylund, H. Fu, 2003 .

Recognition by leukocyte formyl peptide receptors. Promiscuous binding or pattern recognition

J. Bylund, 2002 .

The Host Defense Peptide LL-37 Selectively Permeabilizes Apoptotic Leukocytes

K. Brown, D. Davidson, S. Teneberg, 2008, Antimicrobial Agents and Chemotherapy.

A proinflammatory peptide from Helicobacter pylori activates monocytes to induce lymphocyte dysfunction and apoptosis.

K. Hellstrand, A. Romero, C. Dahlgren, 2001, The Journal of clinical investigation.

The volume of distribution is an indicator of poor in vitro–in vivo extrapolation of clearance for acidic drugs in the rat

U. Fagerholm, J. Bylund, A. Sohlenius-Sternbeck, 2013, Xenobiotica; the fate of foreign compounds in biological systems.

Chronic granulomatous disease: from genetic defect to clinical presentation.

D. Goldblatt, D. Speert, J. Bylund, 2005, Advances in experimental medicine and biology.

Production of exopolysaccharide by Burkholderia cenocepacia results in altered cell-surface interactions and altered bacterial clearance in mice.

B. Conway, D. Speert, J. Bylund, 2004, The Journal of infectious diseases.

Activated low-density granulocytes in peripheral and intervillous blood and neutrophil inflammation in placentas from SLE pregnancies

K. Blennow, B. Jacobsson, H. Zetterberg, 2021, Lupus Science & Medicine.

Intracellular generation of superoxide by the phagocyte NADPH oxidase: how, where, and what for?

K. Brown, C. Movitz, A. Karlsson, 2010, Free radical biology & medicine.

Glycan analysis of human neutrophil granules implicates a maturation-dependent glycosylation machinery

N. Karlsson, Ian Loke, M. Thaysen‐Andersen, 2020, The Journal of Biological Chemistry.

Phenyl isoxazole voltage-gated sodium channel blockers: structure and activity relationship.

P. Lund, P. Arvidsson, L. Sandberg, 2011, Bioorganic & medicinal chemistry letters.

Escape of Mycobacterium tuberculosis from oxidative killing by neutrophils

B. Corleis, U. Schaible, J. Bylund, 2012, Cellular microbiology.

Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like‐1

A. Karlsson, C. Dahlgren, J. Bylund, 2008, Journal of leukocyte biology.

Cloning and characterization of CYP4F21: a prostaglandin E2 20-hydroxylase of ram seminal vesicles.

E. Oliw, J. Bylund, 2001, Archives of biochemistry and biophysics.

Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages

C. Haslett, D. Davidson, P. Hiemstra, 2009, Journal of leukocyte biology.

ROS-deficient monocytes have aberrant gene expression that correlates with inflammatory disorders of chronic granulomatous disease.

R. Hancock, K. Brown, R. Falsafi, 2008, Clinical immunology.

Phenol-Soluble Modulin α Peptide Toxins from Aggressive Staphylococcus aureus Induce Rapid Formation of Neutrophil Extracellular Traps through a Reactive Oxygen Species-Independent Pathway

A. Karlsson, C. Urban, C. Dahlgren, 2017, Frontiers in immunology.

Bisallylic hydroxylation and epoxidation of polyunsaturated fatty acids by cytochrome P450

E. Oliw, J. Bylund, C. Herman, 1996, Lipids.

Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question

C. Dahlgren, H. Forsman, J. Bylund, 2017, PloS one.

Syddansk Universitet The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 ( GPR 43 ) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment

S. Pandey, T. Ulven, H. Forsman, 2016 .

The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment

S. Pandey, C. Dahlgren, T. Ulven, 2016, Molecular and Cellular Biology.

A pepducin designed to modulate P2Y2R function interacts with FPR2 in human neutrophils and transfers ATP to an NADPH-oxidase-activating ligand through a receptor cross-talk mechanism.

Tudor I. Oprea, T. Oprea, C. Dahlgren, 2016, Biochimica et biophysica acta.

P2Y2 receptor signaling in neutrophils is regulated from inside by a novel cytoskeleton-dependent mechanism.

Tudor I. Oprea, T. Oprea, A. Karlsson, 2015, Experimental cell research.

Receptor-Dependent and -Independent Immunomodulatory Effects of Phenol-Soluble Modulin Peptides from Staphylococcus aureus on Human Neutrophils Are Abrogated through Peptide Inactivation by Reactive Oxygen Species

C. Dahlgren, H. Forsman, J. Bylund, 2012, Infection and Immunity.

Cyclosporin H, Boc-MLF and Boc-FLFLF are Antagonists that Preferentially Inhibit Activity Triggered Through the Formyl Peptide Receptor

C. Wennerås, C. Dahlgren, J. Bylund, 2007, Inflammation.

Tumour necrosis factor (TNF)‐α primes murine neutrophils when triggered via formyl peptide receptor‐related sequence 2, the murine orthologue of human formyl peptide receptor‐like 1, through a process involving the type I TNF receptor and subcellular granule mobilization

C. Dahlgren, H. Forsman, J. Bylund, 2008, Immunology.

Outer membrane protein A deficient Escherichia coli activates neutrophils to produce superoxide and shows increased susceptibility to antibacterial peptides.

C. Dahlgren, A. Belaaouaj, J. Bylund, 2003, Microbes and infection.

Problems in identifying microbial-derived neutrophil activators, focusing on Helicobacter pylori.

C. Dahlgren, J. Bylund, 2002, Trends in microbiology.

Cytochrome P450 Enzymes in Oxygenation of Prostaglandin Endoperoxides and Arachidonic Acid Cloning, Expression and Catalytic Properties of CYP4F8 and CYP4F21

J. Bylund, 2000 .

Cytochrome P 450 Enzymes in Oxygenation of Prostaglandin Endoperoxides and Arachidonic Acid Cloning , Expression and Catalytic Properties of CYP

J. Bylund, 2000 .

The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation.

J. Raynes, A. Karlsson, C. Dahlgren, 2010, Arthritis and rheumatism.

Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils.

E. Telemo, K. Brown, A. Karlsson, 2008, Glycobiology.

The non-steroidal anti-inflammatory drug piroxicam blocks ligand binding to the formyl peptide receptor but not the formyl peptide receptor like 1.

C. Wennerås, C. Dahlgren, J. Bylund, 2007, Biochemical pharmacology.

The Human Neutrophil Subsets Defined by the Presence or Absence of OLFM4 Both Transmigrate into Tissue In Vivo and Give Rise to Distinct NETs In Vitro

A. Karlsson, C. Dahlgren, H. Forsman, 2013, PloS one.

Peptidylarginine deiminases present in the airways during tobacco smoking and inflammation can citrullinate the host defense peptide LL-37, resulting in altered activities.

M. Malmsten, Ola Kilsgård, J. Erjefält, 2012, American journal of respiratory cell and molecular biology.

Functional characteristics of circulating granulocytes in severe congenital neutropenia caused by ELANE mutations

Xiaodong Zhao, C. Dahlgren, Wenyan Li, 2019, BMC Pediatrics.

Neutrophils from patients with SAPHO syndrome show no signs of aberrant NADPH oxidase-dependent production of intracellular reactive oxygen species

A. Karlsson, P. Wekell, A. Fasth, 2016, Rheumatology.

Regulation of Neutrophil Apoptosis Differs after in vivo Transmigration to Skin Chambers and Synovial Fluid: A Role for Inflammasome-Dependent Interleukin-1β Release

A. Karlsson, J. Bylund, L. Björkman, 2013, Journal of Innate Immunity.

In vivo‐transmigrated human neutrophils are resistant to antiapoptotic stimulation

C. Movitz, C. Dahlgren, D. Speert, 2011, Journal of leukocyte biology.

Measurement of respiratory burst products generated by professional phagocytes.

A. Karlsson, C. Dahlgren, J. Bylund, 2007, Methods in molecular biology.

In Vivo Transmigrated Human Neutrophils Are Highly Primed for Intracellular Radical Production Induced by Monosodium Urate Crystals

J. Bylund, L. Björkman, K. Christenson, 2020, International journal of molecular sciences.

Immunostimulatory DNA induces degranulation and NADPH‐oxidase activation in human neutrophils while concomitantly inhibiting chemotaxis and phagocytosis

A. Karlsson, A. Tarkowski, J. Bylund, 2002, European journal of immunology.

Midkine Is Expressed and Differentially Processed during Chronic Obstructive Pulmonary Disease Exacerbations and Ventilator-Associated Pneumonia Associated with Staphylococcus aureus Infection

J. Erjefält, A. Egesten, M. Mörgelin, 2013, Molecular Medicine.

CTLA4 Immunoglobulin but Not Anti-Tumor Necrosis Factor Therapy Promotes Staphylococcal Septic Arthritis in Mice.

E. Josefsson, R. Pullerits, J. Bylund, 2015, The Journal of infectious diseases.

Measurement of Respiratory Burst Products, Released or Retained, During Activation of Professional Phagocytes.

C. Dahlgren, J. Bylund, M. Sundqvist, 2019, Methods in molecular biology.

DPI Selectively Inhibits Intracellular NADPH Oxidase Activity in Human Neutrophils

C. Dahlgren, J. Bylund, V. Venkatakrishnan, 2019, ImmunoHorizons.

Measurement of respiratory burst products, released or retained, during activation of professional phagocytes.

A. Karlsson, C. Dahlgren, J. Bylund, 2014, Methods in molecular biology.

Novel L-nucleoside analog, 5-fluorotroxacitabine, displays potent efficacy against acute myeloid leukemia

M. Minden, M. Albertella, R. Hurren, 2019, Haematologica.

Burkholderia cenocepacia Induces Neutrophil Necrosis in Chronic Granulomatous Disease1

B. Conway, D. Speert, J. Bylund, 2005, The Journal of Immunology.

Signal Regulatory Protein Alpha Is Present in Several Neutrophil Granule Populations and Is Rapidly Mobilized to the Cell Surface to Negatively Fine-Tune Neutrophil Accumulation in Inflammation

L. Vesterlund, T. Matozaki, A. Karlsson, 2014, Journal of Innate Immunity.

CFP-10 from Mycobacterium tuberculosis Selectively Activates Human Neutrophils through a Pertussis Toxin-Sensitive Chemotactic Receptor

Tudor I. Oprea, T. Oprea, A. Karlsson, 2014, Infection and Immunity.

Candida albicans promotes neutrophil extracellular trap formation and leukotoxic hypercitrullination via the peptide toxin candidalysin

R. Krüger, H. von Bernuth, C. Urban, 2022, bioRxiv.

Endogenous Acute Phase Serum Amyloid A Lacks Pro-Inflammatory Activity, Contrasting the Two Recombinant Variants That Activate Human Neutrophils through Different Receptors

A. Karlsson, J. Bylund, M. Olsson, 2013, Front. Immunol..

Intracellular Neutrophil Oxidants: From Laboratory Curiosity to Clinical Reality

A. Karlsson, C. Dahlgren, J. Bylund, 2019, The Journal of Immunology.

Neutrophil NET formation is regulated from the inside by myeloperoxidase-processed reactive oxygen species.

E. Michaëlsson, A. Karlsson, C. Dahlgren, 2015, Free radical biology & medicine.

Olfactomedin‐4 autoantibodies give unusual c‐ANCA staining patterns with reactivity to a subpopulation of neutrophils

C. Dahlgren, R. Pullerits, J. Bylund, 2015, Journal of leukocyte biology.

Neutrophil recruitment to inflamed joints can occur without cellular priming

A. Karlsson, C. Dahlgren, H. Forsman, 2019, Journal of leukocyte biology.

Collection of in vivo transmigrated neutrophils from human skin.

A. Karlsson, C. Dahlgren, J. Bylund, 2014, Methods in molecular biology.

Dexamethasone induces bisallylic hydroxylation of polyunsaturated fatty acids by rat liver microsomes.

E. Oliw, J. Bylund, L. Hörnsten, 1996, Archives of biochemistry and biophysics.

This information is current as Mechanism Apoptosis via an NKp 46-and Fas-Dependent Human NK Cells Induce Neutrophil

Marcenaro, F. Thorén, Rebecca Riise, 2012 .

Necrosis in Chronic Granulomatous Disease Burkholderia cenocepacia Induces Neutrophil

B. Conway, D. Speert, J. Bylund, 2013 .

Necrosis in Chronic Granulomatous Disease Induces Neutrophil Burkholderia cenocepacia

B. Conway, D. Speert, J. Bylund, 2005 .

Phagocyte-derived reactive oxygen species as suppressors of inflammatory disease.

K. Brown, A. Karlsson, C. Dahlgren, 2008, Arthritis and rheumatism.

Leukotriene B4 ω-side chain hydroxylation by CYP4F5 and CYP4F6

R. Roman, D. Harder, K. Maier, 2003 .

Presystemic metabolism of AZ'0908, a novel mPGES-1 inhibitor: an in vitro and in vivo cross-species comparison.

J. Bylund, T. Bueters, 2013, Journal of pharmaceutical sciences.

Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient Phagocytes

K. Brown, A. Karlsson, C. Dahlgren, 2017, Front. Immunol..

Leukotriene B4 omega-side chain hydroxylation by CYP4F5 and CYP4F6.

R. Roman, D. Harder, K. Maier, 2003, Archives of biochemistry and biophysics.

Reduced sialyl-Lewisx on salivary MUC7 from patients with burning mouth syndrome.

Shikhar P. Acharya, N. Karlsson, M. Jontell, 2019, Molecular omics.

Reduced sialyl-Lewis on salivary MUC7 from patients with burning mouth syndrome†

Shikhar P. Acharya, N. Karlsson, M. Jontell, 2019 .

Exploration and pharmacokinetic profiling of phenylalanine based carbamates as novel substance p 1-7 analogues.

P. Artursson, A. Sandström, M. Hallberg, 2014, ACS medicinal chemistry letters.

Rat poorly predicts the combined non-absorbed and presystemically metabolized fractions in the human

J. Bylund, T. Bueters, Yin Hu, 2013, Xenobiotica; the fate of foreign compounds in biological systems.

Analysis of cytochrome P450 metabolites of arachidonic and linoleic acids by liquid chromatography-mass spectrometry with ion trap MS.

E. Oliw, J. Ericsson, J. Bylund, 1998, Analytical biochemistry.

Stepwise Design of γ-Secretase Modulators with Advanced Profile by Judicious Coordinated Structural Replacements and an Unconventional Phenyl Ring Bioisostere.

C. Bissantz, W. Neidhart, Lisha Wang, 2020, Journal of medicinal chemistry.

Turning chemoattractant receptors on and off with conventional ligands and allosteric modulators: recent advances in formyl peptide receptor signaling and regulation

C. Dahlgren, H. Forsman, J. Bylund, 2014 .

Ligand recognition and activation of formyl peptide receptors in neutrophils

C. Movitz, A. Karlsson, C. Dahlgren, 2006, Journal of leukocyte biology.

A Pepducin Derived from the Third Intracellular Loop of FPR2 Is a Partial Agonist for Direct Activation of This Receptor in Neutrophils But a Full Agonist for Cross-Talk Triggered Reactivation of FPR2

C. Dahlgren, H. Forsman, J. Bylund, 2014, PloS one.

A novel receptor cross-talk between the ATP receptor P2Y2 and formyl peptide receptors reactivates desensitized neutrophils to produce superoxide.

Tudor I. Oprea, T. Oprea, C. Müller, 2014, Experimental cell research.

Antibacterial Activity of Pepducins, Allosterical Modulators of Formyl Peptide Receptor Signaling

Tudor I. Oprea, T. Oprea, C. Dahlgren, 2014, Antimicrobial Agents and Chemotherapy.

Reactivation of Desensitized Formyl Peptide Receptors by Platelet Activating Factor: A Novel Receptor Cross Talk Mechanism Regulating Neutrophil Superoxide Anion Production

A. Karlsson, C. Dahlgren, H. Forsman, 2013, PloS one.

A methodological approach to studies of desensitization of the formyl peptide receptor: Role of the read out system, reactive oxygen species and the specific agonist used to trigger neutrophils.

C. Movitz, C. Dahlgren, H. Forsman, 2010, Journal of immunological methods.

Reactivation of Formyl Peptide Receptors Triggers the Neutrophil NADPH-oxidase but Not a Transient Rise in Intracellular Calcium*

A. Karlsson, D. Granfeldt, C. Dahlgren, 2003, Journal of Biological Chemistry.

A rare CTSC mutation in Papillon-Lefèvre Syndrome results in abolished serine protease activity and reduced NET formation but otherwise normal neutrophil function

Regis Dieckmann, J. Bylund, M. Sundqvist, 2021, PloS one.

Analyzing cell death events in cultured leukocytes.

F. Thorén, J. Bylund, K. Christenson, 2012, Methods in molecular biology.

Enhanced inflammatory responses of chronic granulomatous disease leukocytes involve ROS‐independent activation of NF‐κB

R. Hancock, K. Brown, P. Mydel, 2007, European journal of immunology.

NADPH-oxidase activation in murine neutrophils via formyl peptide receptors.

A. Karlsson, J. Bylund, L. Collins, 2003, Experimental cell research.

Changes in the ratio between FPR and FPRL1 triggered superoxide production in human neutrophils-a tool in analysing receptor specific events.

A. Karlsson, C. Dahlgren, J. Bylund, 2008, Journal of immunological methods.

Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils

U. Mellqvist, K. Hellstrand, A. Karlsson, 2004, BMC Cell Biology.

Identification of a novel cytochrome P450, CYP4X1, with unique localization specific to the brain.

D. Harder, J. Bylund, Chenyang Zhang, 2002, Biochemical and biophysical research communications.

Identification of CYP4F8 in Human Seminal Vesicles as a Prominent 19-Hydroxylase of Prostaglandin Endoperoxides*

M. Ingelman-Sundberg, E. Oliw, M. Hidestrand, 2000, The Journal of Biological Chemistry.

Inhibition of phospholipase A(2) abrogates intracellular processing of NADPH-oxidase derived reactive oxygen species in human neutrophils.

A. Karlsson, D. Granfeldt, J. Bylund, 2013, Experimental cell research.

Increased CD11b and Decreased CD62L in Blood and Airway Neutrophils from Long-Term Smokers with and without COPD

A. Lindén, K. Ganguly, S. Lindén, 2020, Journal of Innate Immunity.

A simple skin blister technique for the study of in vivo transmigration of human leukocytes.

C. Movitz, F. Thorén, A. Karlsson, 2013, JIM - Journal of Immunological Methods.

Proinflammatory Activity of a Cecropin-Like Antibacterial Peptide from Helicobacter pylori

Anna Karlsson, Claes Dahlgren, T. Nyström, 2001, Antimicrobial Agents and Chemotherapy.

Determination of Subset-Restricted Anti-neutrophil Cytoplasmic Antibodies (ANCA) by Immunofluorescence Cytochemistry.

J. Bylund, A. Welin, Firoozeh Amirbeagi, 2018, Methods in molecular biology.

Galectin‐3 type‐C self‐association on neutrophil surfaces; The carbohydrate recognition domain regulates cell function

A. Karlsson, J. Bylund, A. Welin, 2018, Journal of leukocyte biology.

On the mechanism of biosynthesis of 19-hydroxyprostaglandins of human seminal fluid and expression of cyclooxygenase-2, PGH 19-hydroxylase (CYP4F8) and microsomal PGE synthase-1 in seminal vesicles and vas deferens.

E. Oliw, G. Sahlén, H. Törmä, 2005, Prostaglandins & other lipid mediators.

Oxidation of prostaglandin H2 and prostaglandin H2 analogues by human cytochromes p450: analysis of ω-side chain hydroxy metabolites and four steroisomers of 5-hydroxyprostaglandin I1 by mass spectrometry

E. Oliw, J. Bylund, K. Stark, 2001 .

Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 ( SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA).

Michael Reutlinger, Andreas Zeller, Stefan Kustermann, 2018, Journal of medicinal chemistry.

Serum amyloid A inhibits apoptosis of human neutrophils via a P2X7‐sensitive pathway independent of formyl peptide receptor‐like 1

J. Bylund, L. Björkman, K. Christenson, 2008, Journal of leukocyte biology.

The mechanism for activation of the neutrophil NADPH‐oxidase by the peptides formyl‐Met‐Leu‐Phe and Trp‐Lys‐Tyr‐Met‐Val‐Met differs from that for interleukin‐8

A. Karlsson, C. Dahlgren, J. Bylund, 2004, Immunology.

Lipopolysaccharide-Induced Granule Mobilization and Priming of the Neutrophil Response to Helicobacter pylori Peptide Hp(2-20), Which Activates Formyl Peptide Receptor-Like 1

A. Karlsson, C. Dahlgren, J. Bylund, 2002, Infection and Immunity.

Myeloid and Non-Myeloid Cells TLR/IL-1R Responses in Human Defective Post-Transcriptional Detection and Characterization of

J. Casanova, C. Picard, R. Hancock, 2009 .

IRAK-4 Mutation (Q293X): Rapid Detection and Characterization of Defective Post-Transcriptional TLR/IL-1R Responses in Human Myeloid and Non-Myeloid Cells1

J. Casanova, C. Picard, R. Hancock, 2006, The Journal of Immunology.

Myeloid and Non-Myeloid Cells TLR / IL-1 R Responses in Human Defective Post-Transcriptional Detection and Characterization of Mutation ( Q 293 X ) : RapidIRAK

J. Casanova, C. Picard, R. Hancock, 2006 .

Human Myeloid and Non-Myeloid Cells Post-Transcriptional TLR / IL-1 R Responses and Characterization of Defective Mutation ( Q 293 X ) : Rapid Detection IRAK-4 Speert

J. Casanova, C. Picard, R. Hancock, 2006 .

Phagocyte interactions with Mycobacterium tuberculosis--Simultaneous analysis of phagocytosis, phagosome maturation and intracellular replication by imaging flow cytometry.

A. Karlsson, J. Bylund, A. Welin, 2015, Journal of immunological methods.

Mice Chronically Fed High-Fat Diet Have Increased Mortality and Disturbed Immune Response in Sepsis

N. Andersson, J. Jansson, M. Bokarewa, 2009, PloS one.

The neutrophil subset defined by CD177 expression is preferentially recruited to gingival crevicular fluid in periodontitis

J. Bylund, A. Welin, L. Björkman, 2020, Journal of leukocyte biology.

Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes.

E. Oliw, J. Bylund, K. Valmsen, 1998, The Journal of pharmacology and experimental therapeutics.

Human Synovial Lubricin Expresses Sialyl Lewis x Determinant and Has L-selectin Ligand Activity*

N. Karlsson, M. Bokarewa, T. Eisler, 2012, The Journal of Biological Chemistry.

Galectin-3 Is a Target for Proteases Involved in the Virulence of Staphylococcus aureus

E. Josefsson, A. Karlsson, L. Shaw, 2017, Infection and Immunity.

Practical use of the regression offset approach for the prediction of in vivo intrinsic clearance from hepatocytes

Douglas Ferguson, Lovisa Afzelius, Brian Middleton, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

cDna cloning and expression of CYP4F12, a novel human cytochrome P450.

E. Oliw, J. Bylund, M. Bylund, 2001, Biochemical and biophysical research communications.

Lectins Offer New Perspectives in the Development of Macrophage-Targeted Therapies for COPD/Emphysema

S. Hodge, G. Hodge, P. Reynolds, 2013, PloS one.

The Role of Formyl Peptide Receptors for Immunomodulatory Activities of Antimicrobial Peptides and Peptidomimetics.

H. Franzyk, H. Forsman, J. Bylund, 2018, Current pharmaceutical design.

Metabolic profiling of TRPV1 antagonists of the benzothiazole amide series: implications for in vitro genotoxicity assessment

S. Czene, A. Lindgren, C. Petersson, 2013, Xenobiotica; the fate of foreign compounds in biological systems.

Systemic Galectin-3 in Smokers with Chronic Obstructive Pulmonary Disease and Chronic Bronchitis: The Impact of Exacerbations

A. Lindén, A. Ekberg-Jansson, J. Bylund, 2021, International journal of chronic obstructive pulmonary disease.

Host Defense Peptide LL-37 Selectively Reduces Proinflammatory Macrophage Responses

R. Hancock, K. Brown, A. Karlsson, 2011, The Journal of Immunology.

Hyper-truncated Asn355- and Asn391-glycans modulate the activity of neutrophil granule myeloperoxidase

Oliver C. Grant, R. Woods, B. Parker, 2020, The Journal of biological chemistry.

Metabotropic Glutamate Receptor Activation Enhances the Activities of Two Types of Ca2+-Activated K+Channels in Rat Hippocampal Astrocytes

R. Koehler, D. Harder, D. Gebremedhin, 2003, The Journal of Neuroscience.

Staphylokinase Control of Staphylococcus aureus Biofilm Formation and Detachment Through Host Plasminogen Activation.

B. Johansson, P. Verhamme, T. Foster, 2016, The Journal of infectious diseases.

ResponsesReduces Proinflammatory Macrophage Host Defense Peptide LL-37 Selectively

R. Hancock, K. Brown, R. Falsafi, 2011 .

The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions

T. Andersson, L. Afzelius, J. Bylund, 2014, Drug Metabolism and Disposition.

Galectin-3 enhances monocyte-derived macrophage efferocytosis of apoptotic granulocytes in asthma

K. Baines, L. Donnelly, A. Karlsson, 2019, Respiratory Research.

Short chain fatty acids released by Fusobacterium nucleatum are neutrophil chemoattractants acting via free fatty acid receptor 2 (FFAR2)

J. Bylund, V. Venkatakrishnan, K. Christenson, 2021, Cellular microbiology.

Importance of Virulence Factors for the Persistence of Oral Bacteria in the Inflamed Gingival Crevice and in the Pathogenesis of Periodontal Disease

G. Dahlén, J. Bylund, A. Basic, 2019, Journal of clinical medicine.

The secretion of cytokines by peripheral blood mononuclear cells of patients with periodontitis and healthy controls when exposed to H2S

G. Dahlén, J. Bylund, Å. Leonhardt, 2021, Journal of oral microbiology.

Porphyromonas gingivalis Produce Neutrophil Specific Chemoattractants Including Short Chain Fatty Acids

Otto Savolainen, C. Dahlgren, H. Forsman, 2021, Frontiers in Cellular and Infection Microbiology.

Gene expression of a novel cytochrome P450 of the CYP4F subfamily in human seminal vesicles.

E. Oliw, J. Bylund, N. Finnström, 1999, Biochemical and biophysical research communications.

Hyper-Truncated Glycans Augment the Activity of Neutrophil Granule Myeloperoxidase

Oliver C. Grant, R. Woods, B. Parker, 2020, bioRxiv.

Hyper-Truncated N-Acetyl-β-D-Glucosamine Decorations Augment the Activity and Inhibition Potential of Neutrophil Granule Myeloperoxidase

Oliver C. Grant, R. Woods, B. Parker, 2020 .

Interleukin-8-Derived Peptide Has Antibacterial Activity

Anna Karlsson, Claes Dahlgren, A. Karlsson, 2005, Antimicrobial Agents and Chemotherapy.

The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the agonist.

A. Karlsson, C. Dahlgren, H. Forsman, 2008, Glycobiology.

Glycoproteome remodelling and granule-specific N-glycosylation accompany neutrophil granulopoiesis

Ian Loke, M. Thaysen‐Andersen, Harry C. Tjondro, 2023, bioRxiv.

A sample preparation method for microbiological analysis of seeds

J. Bylund, 2013 .

Cord-forming mycobacteria induce DNA meshwork formation by human peripheral blood mononuclear cells.

E. Telemo, B. Johansson, J. Bylund, 2013, Pathogens and disease.

Low-density granulocytes are related to shorter pregnancy duration but not to interferon alpha protein blood levels in systemic lupus erythematosus

K. Blennow, B. Jacobsson, H. Zetterberg, 2023, Arthritis Research & Therapy.

Novel inhibitory effect of galectin-3 on the respiratory burst induced by Staphylococcus aureus in human neutrophils

Linda Bergqvist, J. Bylund, A. Welin, 2023, Glycobiology.

The FPR2-specific ligand MMK-1 activates the neutrophil NADPH-oxidase, but triggers no unique pathway for opening of plasma membrane calcium channels.

C. Dahlgren, H. Forsman, J. Bylund, 2009, Cell calcium.

Antibacterial Activity of Pepducins, Allosterical Modulators of

Tudor I. Oprea, C. Dahlgren, H. Forsman, 2014 .

Receptor Signaling Allosterical Modulators of Formyl Peptide Antibacterial Activity of Pepducins

Tudor I. Oprea, C. Dahlgren, H. Forsman, 2014 .

Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment

A Rominger, P. Cumming, A. Rominger, 2015, Molecular Psychiatry.

Rat poorly predicts the combined non-absorbed and presystemically metabolized fractions in the human

J. Bylund, T. Bueters, Yin Hu, 2013, Xenobiotica; the fate of foreign compounds in biological systems.

The Impact of Solute Carrier (SLC) Drug Uptake Transporter Loss in Human and Rat Cryopreserved Hepatocytes on Clearance Predictions

T. Andersson, L. Afzelius, J. Bylund, 2014, Drug Metabolism and Disposition.

Potent and orally efficacious benzothiazole amides as TRPV1 antagonists.

D. Labrecque, M. Maudet, M. Svensson, 2012, Bioorganic & medicinal chemistry letters.

NADPH-OXIDASE DERIVED REACTIVE OXYGEN SPECIES IN HUMAN NEUTROPHILS

D. Granfeldt, J. Bylund, A. Welin, 2012 .

MPO deficiency confers impaired processing of neutrophil reactive oxygen species in a patient with severe CRMO

A. Karlsson, P. Wekell, S. Berg, 2015, Pediatric Rheumatology.

The peptide Trp-Lys-Tyr-Met-Val-D-Met activates neutrophils through the formyl peptide receptor only when signaling through the formylpeptide receptor like 1 is blocked. A receptor switch with implications for signal transduction studies with inhibitors and receptor antagonists.

C. Dahlgren, J. Bylund, F. Boulay, 2006, Biochemical pharmacology.

Protein N-glycosylation in the bronchoalveolar space differs between never-smokers and long-term smokers with and without COPD

N. Karlsson, J. Bylund, M. Padra, 2023, Glycobiology.