V. Alezra

发表

Interfering peptides targeting protein-protein interactions: the next generation of drugs?

P. Tufféry, A. Rebollo, N. Wolff, 2017, Drug discovery today.

Tertiary aromatic amide for memory of chirality: access to enantioenriched alpha-substituted valine.

R. Guillot, C. Kouklovsky, M. Branca, 2008, Journal of the American Chemical Society.

Frozen Chirality of Tertiary Aromatic Amides: Access to Enantioenriched Tertiary α-Amino Acid or Amino Alcohol without Chiral Reagent.

R. Guillot, C. Kouklovsky, Jean‐Valère Naubron, 2017, Chemistry.

Absolute asymmetric synthesis of tertiary α-amino acids.

R. Guillot, C. Kouklovsky, M. Branca, 2012, Angewandte Chemie.

β,γ-diamino acids as building blocks for new analogues of Gramicidin S: Synthesis and biological activity.

S. Zirah, Yang Wan, C. Kouklovsky, 2018, European journal of medicinal chemistry.

[CpRu((R)-Binop-F)(H2O)][SbF6], a new fluxional chiral Lewis acid catalyst: synthesis, dynamic nmr, asymmetric catalysis, and theoretical studies.

C. Saudan, G. Bernardinelli, C. Corminboeuf, 2004, Journal of the American Chemical Society.

Foldamers containing γ-amino acid residues or their analogues: structural features and applications

C. Kouklovsky, V. Alezra, Francelin Bouillère, 2011, Amino Acids.

Unexpected dimerization of a tripeptide comprising a β,γ‐diamino acid

E. Miclet, J. Baltaze, Yang Wan, 2019, Journal of peptide science : an official publication of the European Peptide Society.

Memory of chirality of tertiary aromatic amide: application to the asymmetric synthesis of (S)-α-methylDOPA.

C. Kouklovsky, V. Alezra, D. Gori, 2012, The Journal of organic chemistry.

Oxidative coupling of enolates using memory of chirality: an original enantioselective synthesis of quaternary α-amino acid derivatives.

R. Guillot, C. Kouklovsky, V. Alezra, 2018, Chemical communications.

Recent Progress in Memory Of Chirality (MOC): An Advanced Chiral Pool

T. Kawabata, V. Alezra, 2016 .

Access to β,γ-diamino acids. Application to the synthesis of 3-deoxyaminostatine.

R. Guillot, C. Kouklovsky, V. Alezra, 2011, Organic & biomolecular chemistry.

3-Aminopyrrolidines from alpha-aminoacids: total synthesis of (+)-nemonapride from D-alanine.

C. Kouklovsky, V. Alezra, V. Nguyen, 2008, The Journal of organic chemistry.

A stereoselective entry into functionalized 1,2-diamines by zinc-mediated homologation of alpha-aminoacids.

R. Guillot, C. Kouklovsky, V. Alezra, 2007, Organic Letters.

Highly Stereoselective Aldol Reactions by Memory of Chirality: Synthesis of Quaternary β‐Hydroxy α‐Amino Acids

R. Guillot, C. Kouklovsky, V. Alezra, 2021, Helvetica Chimica Acta.

Memory of Chirality in a Flow‐Based System: Enantioselective Synthesis of Quaternary α‐Amino Acids Using Flow Microreactors

J. Yoshida, Heejin Kim, C. Kouklovsky, 2018 .

Memory of chirality of tertiary aromatic amides: a simple and efficient method for the enantioselective synthesis of quaternary alpha-amino acids.

R. Guillot, C. Kouklovsky, M. Branca, 2009, Journal of the American Chemical Society.

Substrate control in enantioselective and diastereoselective aldol reaction by memory of chirality: a rapid access to enantiopure β-hydroxy quaternary α-amino acids.

R. Guillot, C. Kouklovsky, V. Alezra, 2014, Organic letters.

Amino acid homologation by the Blaise reaction: a new entry into nitrogen heterocycles.

C. Kouklovsky, V. Alezra, D. Gori, 2009, The Journal of organic chemistry.

The Origin of Chemical and Configurational Stability of Chiral Nonracemic tert‐Butyl Aziridinecarboxylate Anions

C. Policar, V. Alezra, L. Micouin, 2001 .

Practical preparation and substitution of configurationally stable aziridinyl ester anions

V. Alezra, L. Micouin, H. Husson, 2000 .

Fast ester cleavage of sterically hindered α- and β-aminoesters under non-aqueous conditions. Application to the kinetic resolution of aziridine esters

V. Alezra, L. Micouin, H. Husson, 2000 .

[(Indenyl)Ru(biphop-F)]+: A Lewis Acid Catalyst that Controls Both the Diene and the Dienophile Facial Selectivity in Diels—Alder Reactions.

C. Saudan, G. Bernardinelli, F. Viton, 2002 .

Asymmetric functionalization of a chiral non-racemic oxazolidine ester enolate. A new route towards the preparation of quaternary serine esters

A. Chiaroni, V. Alezra, L. Micouin, 2000 .

β,γ-Diamino acid: an original building block for hybrid α/γ-peptide synthesis with extra hydrogen bond donating group

E. Miclet, R. Guillot, C. Kouklovsky, 2014, Amino Acids.

Asymmetric synthesis of quaternary tetrahydroisoquinoline-3-carboxylic acid derivatives

V. Alezra, L. Micouin, H. Husson, 2001 .

Constrained Cyclic β,γ‐Diamino Acids from Glutamic Acid: Synthesis of Both Diastereomers and Unexpected Kinetic Resolution

Yang Wan, R. Guillot, C. Kouklovsky, 2018 .

Efficient synthesis of both diastereomers of β,γ-diamino acids from phenylalanine and tryptophan

R. Guillot, C. Kouklovsky, V. Alezra, 2016, Amino Acids.

Original β,γ-diamino acid as an inducer of a γ-turn mimic in short peptides.

E. Miclet, J. Baltaze, F. Brisset, 2012, Organic & biomolecular chemistry.

Constrained α/γ-peptides: a new stable extended structure in solution without any hydrogen bond and characterized by a four-fold symmetry.

E. Miclet, R. Guillot, C. Kouklovsky, 2012, Chemical communications.

A Stereoselective Entry into Functionalized 1,2-Diamines by Zinc-Mediated Homologation of α-Amino Acids.

R. Guillot, C. Kouklovsky, V. Alezra, 2007 .

Accurate conformation analysis in solution: NMR and DFT/PCM study of the S-3-(1-naphthoyl)-4-isopropyl-2,2-dimethyloxazolidin-5-one in CDCl3

P. Archirel, C. Kouklovsky, M. Branca, 2008 .

Recent Advances in the Exploration of Therapeutic Analogues of Gramicidin S, an Old but Still Potent Antimicrobial Peptide.

Yi Jin, Yang Wan, V. Alezra, 2019, Journal of medicinal chemistry.

Antimicrobial peptides: triumphs and challenges.

Yang Wan, V. Alezra, Shuhui Huang, 2021, Future medicinal chemistry.

Development of Therapeutic Gramicidin S Analogues Bearing Plastic β,γ‐Diamino Acids

Yi Jin, E. Miclet, Yang Wan, 2020, ChemMedChem.

Customized Reversible Stapling for Selective Delivery of Bioactive Peptides.

Huanwen Chen, Yi Jin, E. Miclet, 2022, Journal of the American Chemical Society.

(R,R)-1,2-Diphenyl-1,2-[di(pentafluorophenyl)phosphanoxy]ethane

V. Alezra, E. P. Kündig, 2002 .

Using the Noncanonical Metallo-Amino Acid [Cu(II)(2,2'-Bipyridin-5-yl)]-alanine to Study the Structures of Proteins.

C. Kouklovsky, S. Un, V. Alezra, 2023, The journal of physical chemistry letters.

Polymyxin B-inspired non-hemolytic tyrocidine A analogues with significantly enhanced activity against gram-negative bacteria: How cationicity impacts cell specificity and antibacterial mechanism.

Yi Jin, Yang Wan, Yuanying Fang, 2021, European journal of medicinal chemistry.

Rapid Formation of Intramolecular Disulfide Bridges using Light: An Efficient Method to Control the Conformation and Function of Bioactive Peptides.

Yang Wan, V. Alezra, Jinhua Zhu, 2023, Journal of the American Chemical Society.