A. Chimento

发表

Biological activity of 3-chloro-azetidin-2-one derivatives having interesting antiproliferative activity on human breast cancer cell lines.

E. Novellino, A. Bertamino, I. Gomez-Monterrey, 2013, Bioorganic & medicinal chemistry letters.

Inhibition of human topoisomerase I and II and anti-proliferative effects on MCF-7 cells by new titanocene complexes.

P. Longo, C. Saturnino, A. Caruso, 2015, Bioorganic & medicinal chemistry.

The biochemical properties of the mitochondrial thiamine pyrophosphate carrier from Drosophila melanogaster

A. Santoro, D. Iacopetta, F. Palmieri, 2010, The FEBS journal.

Steroid Receptor Signallings as Targets for Resveratrol Actions in Breast and Prostate Cancer

I. Casaburi, F. De Amicis, A. Chimento, 2019, International journal of molecular sciences.

Antitumoral Activities of Curcumin and Recent Advances to ImProve Its Oral Bioavailability

I. Casaburi, F. Puoci, A. Chimento, 2021, Biomedicines.

17β-Estradiol activates rapid signaling pathways involved in rat pachytene spermatocytes apoptosis through GPR30 and ERα

S. Andò, M. Maggiolini, S. Carreau, 2010, Molecular and Cellular Endocrinology.

Gper and ESRs are expressed in rat round spermatids and mediate oestrogen-dependent rapid pathways modulating expression of cyclin B1 and Bax.

S. Andò, S. Aquila, F. Zolea, 2011, International journal of andrology.

Effects of Atrazine on Estrogen Receptor α– and G Protein–Coupled Receptor 30–Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts

E. Prossnitz, M. Maggiolini, L. Albanito, 2015, Environmental health perspectives.

Estrogen Receptors-Mediated Apoptosis in Hormone-Dependent Cancers

I. Casaburi, F. De Amicis, A. Chimento, 2022, International journal of molecular sciences.

Synthesis of a new bis(indolyl)methane that inhibits growth and induces apoptosis in human prostate cancer cells

X. Cachet, F. Conforti, G. Statti, 2013, Natural product research.

A Phenylacetamide Resveratrol Derivative Exerts Inhibitory Effects on Breast Cancer Cell Growth

A. Santarsiero, V. Infantino, C. Saturnino, 2021, International journal of molecular sciences.

Role of Scaffold Protein Proline-, Glutamic Acid-, and Leucine-Rich Protein 1 (PELP1) in the Modulation of Adrenocortical Cancer Cell Growth

I. Casaburi, C. Pilon, A. Chimento, 2017, Cells.

Differential expression of steroidogenic factor-1/adrenal 4 binding protein and liver receptor homolog-1 (LRH-1)/fetoprotein transcription factor in the rat testis: LRH-1 as a potential regulator of testicular aromatase expression.

S. Andò, M. Maggiolini, E. Simpson, 2004, Endocrinology.

Inhibition of Cyclooxygenase-2 Down-regulates Aromatase Activity and Decreases Proliferation of Leydig Tumor Cells*

S. Andò, F. Zolea, M. Maggiolini, 2009, The Journal of Biological Chemistry.

GPER Signaling in Spermatogenesis and Testicular Tumors

I. Casaburi, A. Chimento, R. Sirianni, 2014, Front. Endocrinol..

Notch Signaling in Breast Tumor Microenvironment as Mediator of Drug Resistance

F. De Amicis, A. Chimento, V. Pezzi, 2022, International journal of molecular sciences.

Triiodothyronine decreases the activity of the proximal promoter (PII) of the aromatase gene in the mouse Sertoli cell line, TM4.

C. Giordano, S. Catalano, S. Andò, 2003, Molecular endocrinology.

G-Protein–Coupled Receptor 30 and Estrogen Receptor-α Are Involved in the Proliferative Effects Induced by Atrazine in Ovarian Cancer Cells

E. Prossnitz, M. Maggiolini, L. Albanito, 2008, Environmental health perspectives.

Nandrolone and stanozolol induce leydig cell tumor proliferation through an estrogen‐dependent mechanism involving IGF‐I system

S. Catalano, S. Andò, M. Lanzino, 2012, Journal of cellular physiology.

Role of GPER-Mediated Signaling in Testicular Functions and Tumorigenesis

A. Chimento, V. Pezzi, P. Avena, 2020, Cells.

F. Sotgia, M. Fiorillo, M. Lisanti, 2015, Oncotarget.

SIRT1 is involved in adrenocortical cancer growth and motility

I. Casaburi, A. Chimento, R. Sirianni, 2021, Journal of cellular and molecular medicine.

C-MYC modulation induces responsiveness to paclitaxel in adrenocortical cancer cell lines.

V. Toscano, L. Cerquetti, B. Bucci, 2015, International journal of oncology.

Olea europaea L. Flowers as a new promising anticancer natural product: phenolic composition, antiproliferative activity and apoptosis induction

E. Perri, M. Zarrouk, N. Trabelsi, 2019, Natural product research.

Oleuropein and hydroxytyrosol inhibit MCF-7 breast cancer cell proliferation interfering with ERK1/2 activation.

S. Andò, P. Rizza, I. Casaburi, 2010, Molecular nutrition & food research.

Potential of olive oil phenols as chemopreventive and therapeutic agents against cancer: a review of in vitro studies.

I. Casaburi, F. Puoci, A. Chimento, 2013, Molecular nutrition & food research.

Selective GPER activation decreases proliferation and activates apoptosis in tumor Leydig cells

S. Andò, I. Casaburi, M. Bartucci, 2013, Cell Death and Disease.

Catalytic Double Cyclization Process for Antitumor Agents against Breast Cancer Cell Lines

B. Gabriele, R. Mancuso, A. Chimento, 2018, iScience.

Synthesis and cytotoxic activity evaluation of 2,3-thiazolidin-4-one derivatives on human breast cancer cell lines.

E. Novellino, A. Bertamino, I. Gomez-Monterrey, 2013, Bioorganic & medicinal chemistry letters.

Insulin-like growth factor-I, regulating aromatase expression through steroidogenic factor 1, supports estrogen-dependent tumor Leydig cell proliferation.

S. Andò, A. Chimento, R. Sirianni, 2007, Cancer research.

Progress to Improve Oral Bioavailability and Beneficial Effects of Resveratrol

I. Casaburi, F. Puoci, C. Saturnino, 2019, International journal of molecular sciences.

Design, synthesis, and structure-activity relationships of azolylmethylpyrroloquinolines as nonsteroidal aromatase inhibitors.

S. Moro, R. Hartmann, G. Basso, 2013, Journal of medicinal chemistry.

Resveratrol and Its Analogs As Antitumoral Agents For Breast Cancer Treatment.

C. Saturnino, A. Caruso, M. Sinicropi, 2016, Mini reviews in medicinal chemistry.

Resveratrol, Epigallocatechin Gallate and Curcumin for Cancer Therapy: Challenges from Their Pro-Apoptotic Properties

F. Conforti, F. De Amicis, A. Chimento, 2023, Life.

Antiproliferative activity of some 1,4-dimethylcarbazoles on cells that express estrogen receptors: part I

S. Rault, C. Saturnino, A. Caruso, 2012, Journal of enzyme inhibition and medicinal chemistry.

Role of Estrogen Receptors and G Protein-Coupled Estrogen Receptor in Regulation of Hypothalamus–Pituitary–Testis Axis and Spermatogenesis

I. Casaburi, A. Chimento, R. Sirianni, 2013, Front. Endocrinol..

The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17beta-estradiol on mouse spermatogonial GC-1 cell line.

S. Andò, M. Maggiolini, R. Lappano, 2008, Endocrinology.

Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells.

C. Rosano, I. Casaburi, M. Maggiolini, 2014, Molecular nutrition & food research.

DAX-1, as an androgen-target gene, inhibits aromatase expression: a novel mechanism blocking estrogen-dependent breast cancer cell proliferation

C. Giordano, I. Barone, S. Catalano, 2013, Cell Death and Disease.

Statins Reduce Intratumor Cholesterol Affecting Adrenocortical Cancer Growth

I. Casaburi, V. Rago, C. Pilon, 2020, Molecular Cancer Therapeutics.

The Involvement of Natural Polyphenols in Molecular Mechanisms Inducing Apoptosis in Tumor Cells: A Promising Adjuvant in Cancer Therapy

F. De Amicis, A. Chimento, V. Pezzi, 2023, International journal of molecular sciences.

Nandrolone and stanozolol upregulate aromatase expression and further increase IGF-I-dependent effects on MCF-7 breast cancer cell proliferation

S. Catalano, S. Andò, M. Lanzino, 2012, Molecular and Cellular Endocrinology.

17β-Estradiol activates GPER- and ESR1-dependent pathways inducing apoptosis in GC-2 cells, a mouse spermatocyte-derived cell line

S. Andò, I. Casaburi, M. Maggiolini, 2012, Molecular and Cellular Endocrinology.

Cross-talk between GPER and growth factor signaling

M. Maggiolini, R. Lappano, A. Chimento, 2013, The Journal of Steroid Biochemistry and Molecular Biology.

Cholesterol and Its Metabolites in Tumor Growth: Therapeutic Potential of Statins in Cancer Treatment

I. Casaburi, V. Rago, A. Chimento, 2019, Front. Endocrinol..

I. Casaburi, C. Hantel, M. Giulietti, 2022, Cancers.

Cholesterol as an Endogenous ERRα Agonist: A New Perspective to Cancer Treatment

I. Casaburi, V. Rago, A. Chimento, 2018, Front. Endocrinol..

Targeting estrogen receptor-α reduces adrenocortical cancer (ACC) cell growth in vitro and in vivo: potential therapeutic role of selective estrogen receptor modulators (SERMs) for ACC treatment.

G. Arnaldi, L. Cerquetti, A. Stigliano, 2012, The Journal of clinical endocrinology and metabolism.

GPER agonist G-1 decreases adrenocortical carcinoma (ACC) cell growth in vitro and in vivo

L. Cerquetti, D. Amendola, A. Stigliano, 2015, Oncotarget.

Retinoylation Reaction of Proteins in Leydig (TM-3) Cells

G. Genchi, E. Cione, A. Chimento, 2005, Journal of bioenergetics and biomembranes.

Cdk4 Regulates Glioblastoma Cell Invasion and Stemness and Is Target of a Notch Inhibitor Plus Resveratrol Combined Treatment

S. Andò, F. Conforti, F. Giordano, 2023, International journal of molecular sciences.

A Resveratrol Phenylacetamide Derivative Perturbs the Cytoskeleton Dynamics Interfering with the Migration Potential in Breast Cancer

C. Rosano, C. Saturnino, D. Iacopetta, 2022, Applied Sciences.

Adrenocortical Carcinoma (ACC) Cells Rewire Their Metabolism to Overcome Curcumin Antitumoral Effects Opening a Window of Opportunity to Improve Treatment

I. Casaburi, C. Hantel, A. Chimento, 2023, Cancers.

GPER-independent inhibition of adrenocortical cancer growth by G-1 involves ROS/Egr-1/BAX pathway

I. Casaburi, V. Rago, W. Rainey, 2017, Oncotarget.

Cross-talk between GPER and growth factor signaling

M. Maggiolini, R. Lappano, A. Chimento, 2013, The Journal of Steroid Biochemistry and Molecular Biology.

Effects of Atrazine on Estrogen Receptor α– and G Protein–Coupled Receptor 30–Mediated Signaling and Proliferation in Cancer Cells and Cancer-Associated Fibroblasts

E. Prossnitz, M. Maggiolini, L. Albanito, 2015, Environmental health perspectives.

Synthesis and cytotoxic activity evaluation of 2,3-thiazolidin-4-one derivatives on human breast cancer cell lines.

E. Novellino, A. Bertamino, I. Gomez-Monterrey, 2013, Bioorganic & medicinal chemistry letters.