O. Déas

发表

Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of αVβ3-expressing endothelial cells

P. Rustin, C. Péchoux, D. Chauvier, 2007, Cell Death and Differentiation.

Abstract 5273: XenTech patient-derived xenograft (PDX) panels: a clinically relevant platform for drug efficacy, target validation and predictive biomarker discovery studies

S. Cairo, M. Poupon, O. Déas, 2012 .

Murine model of hepatic breast cancer

Matthew N. Svalina, C. Keller, S. Cairo, 2016, Biochemistry and biophysics reports.

An NF90/NF110-Mediated Feedback Amplification Loop Regulates DICER Expression and Controls Ovarian Carcinoma Progression

W. Ritchie, P. Giraud, X. Contreras, 2018, Cell Research.

Antibodies, a Potent Tool to Target Genes into Designated Cells and Tissues

A. Durrbach, F. Hirsch, O. Déas, 2004 .

Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents

S. Cairo, M. Poupon, V. Goffin, 2016, Oncotarget.

Human growth hormone gene transfer into tumor cells may improve cancer chemotherapy

G. Vassal, J. Merlin, J. Bénard, 2002, Cancer Gene Therapy.

Thiol-mediated inhibition of FAS and CD2 apoptotic signaling in activated human peripheral T cells.

D. Métivier, B. Charpentier, F. Hirsch, 1997, International immunology.

Growth hormone prevents human monocytic cells from Fas‐mediated apoptosis by up‐regulating Bcl‐2 expression

J. Estaquier, B. Charpentier, F. Hirsch, 1999, European journal of immunology.

Targeting genome integrity dysfunctions impedes metastatic potency in non–small cell lung cancer circulating tumor cell–derived explants

S. Cairo, D. Planchard, J. Scoazec, 2022, JCI insight.

A flavivirus protein M-derived peptide directly permeabilizes mitochondrial membranes, triggers cell death and reduces human tumor growth in nude mice

S. Muller, D. Chauvier, R. Casimir, 2009, Apoptosis.

Effects of anti-CD2 monoclonal antibody: CD2- and CD95-mediated apoptosis of human peripheral T cells.

B. Charpentier, B. Mollereau, O. Déas, 1999, Transplantation proceedings.

(BTI-322) in Activated Human Peripheral T Cells Unresponsiveness Induced by a Single CD2 mAb Potent Apoptotic Signaling and Subsequent

A. Bernard, Bernard, F. Hirsch, 1998 .

Potentiation of tumour apoptosis by human growth hormone via glutathione production and decreased NF-κB activity

G. Vassal, J. Bénard, A. Dürrbach, 2003, British Journal of Cancer.

In vivo-targeted gene delivery using antibody-based nonviral vector.

E. Oosterwijk, A. Dürrbach, B. Charpentier, 2002, Human gene therapy.

Caspase-independent cell death induced by anti-CD2 or staurosporine in activated human peripheral T lymphocytes.

G. Cohen, M. MacFarlane, F. Harper, 1998, Journal of immunology.

Abstract P5-06-04: The PARP inhibitor niraparib demonstrated activity in patient-derived triple-negative breast cancer xenograft models with high homologous recombination deficiency (HRD) score

S. Cairo, A. Gutin, J. Lanchbury, 2015 .

Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells.

P. Rustin, C. Péchoux, D. Chauvier, 2007, Cell death and differentiation.

Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification.

S. Nik-Zainal, C. Caldas, S. Cairo, 2022, Cancer research.

A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation

C. Caldas, J. Baselga, S. Cairo, 2018, EMBO molecular medicine.

N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis

Jie-Wei Chen, J. Yun, Z. Pan, 2019, Nature Communications.

The sialyl-glycolipid stage-specific embryonic antigen 4 marks a subpopulation of chemotherapy-resistant breast cancer cells with mesenchymal features

A. Schneeweiss, A. Trumpp, S. Cairo, 2015, Breast Cancer Research.

The sialyl-glycolipid stage-specific embryonic antigen 4 marks a subpopulation of chemotherapy-resistant breast cancer cells with mesenchymal features

A. Schneeweiss, A. Trumpp, S. Cairo, 2015, Breast Cancer Research.

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

B. Sobhian, Y. Lévy, Clarisse Benne, 2012, Molecular cell.

Genetic characterization of a unique neuroendocrine transdifferentiation prostate circulating tumor cell-derived eXplant model

S. Cairo, N. Manaresi, N. Stoecklein, 2020, Nature Communications.

Human Peripheral T Lymphocytes Anti-CD 2 or Staurosporine in Activated Caspase-Independent Cell Death Induced by

G. Cohen, M. MacFarlane, F. Harper, 1998 .

Association of FGFR1 with ERα Maintains Ligand-Independent ER Transcription and Mediates Resistance to Estrogen Deprivation in ER+ Breast Cancer

S. Cairo, K. Hutchinson, A. Guerrero-Zotano, 2017, Clinical Cancer Research.

Patient‐derived mouse xenografts from pediatric liver cancer predict tumor recurrence and advise clinical management

S. Cairo, E. Fadel, M. Ghigna, 2016, Hepatology.

Inhibitory effect of growth hormone on TNF-alpha secretion and nuclear factor-kappaB translocation in lipopolysaccharide-stimulated human monocytes.

S. Wright, B. Charpentier, F. Hirsch, 1997, Journal of immunology.

The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient–Derived Xenograft Models

Rhys D O Jones, S. Cairo, S. Fawell, 2015, Clinical Cancer Research.

Title: Association of FGFR1 with ER  maintains ligand-independent ER transcription and 1 mediates resistance to estrogen deprivation in ER+ breast cancer 2

S. Cairo, K. Hutchinson, J. Balko, 2017 .

Abstract 318: Mechanisms of acquired resistance to FGFR inhibitors in molecularly-selected solid tumors: A prospective cohort from the MATCH-R study

J. Thiery, E. Solary, A. Eggermont, 2019, Experimental and Molecular Therapeutics.

In vivo gene targeting of IL-3 into immature hematopoietic cells through CD117 receptor mediated antibody gene delivery

J. Aigueperse, A. Dürrbach, F. Hirsch, 2004, Genetic vaccines and therapy.

Peripheral blood T cells generated after allogeneic bone marrow transplantation: lower levels of bcl-2 protein and enhanced sensitivity to spontaneous and CD95-mediated apoptosis in vitro. Abrogation of the apoptotic phenotype coincides with the recovery of normal naive/primed T-cell profiles.

B. Charpentier, A. Durrbach, J. Vernant, 1999, Blood.

Feasibility and first reports of the MATCH-R repeated biopsy trial at Gustave Roussy

E. Solary, D. Planchard, A. Eggermont, 2020, npj Precision Oncology.

Potent apoptotic signaling and subsequent unresponsiveness induced by a single CD2 mAb (BTI-322) in activated human peripheral T cells.

A. Bernard, B. Charpentier, F. Hirsch, 1998, Journal of immunology.

CD2-induced apoptosis in activated human peripheral T cells: a Fas-independent pathway that requires early protein tyrosine phosphorylation.

F. Rieux-Laucat, M. Deckert, A. Bernard, 1996, Journal of immunology.

Targeting additional costimulatory pathways: a subtle role for CD2.

B. Charpentier, A. Durrbach, F. Hirsch, 2001, Transplantation proceedings.

Relationship between proliferation and susceptibility to CD95- and CD2-mediated apoptosis in stimulated primary T lymphocytes: T cells manifesting proliferative unresponsiveness are preferentially susceptible to CD95-mediated apoptosis.

A. Bernard, B. Charpentier, B. Mollereau, 1997, Journal of immunology.

MiR-205 as predictive biomarker and adjuvant therapeutic tool in combination with trastuzumab

M. Iorio, S. Cairo, E. Tagliabue, 2018, Oncotarget.

Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer

S. Cairo, S. Vacher, S. Roman-Roman, 2015, British Journal of Cancer.

Diverse Resistance Mechanisms to the Third-Generation ALK Inhibitor Lorlatinib in ALK-Rearranged Lung Cancer

J. Thiery, E. Solary, D. Planchard, 2019, Clinical Cancer Research.

Synergic activity of FGFR2 and MEK inhibitors in the treatment of FGFR2-amplified cancers of unknown primary

M. Ferracin, G. Calin, E. Porcellini, 2023, medRxiv.