Nigus D. Ambaye

发表

Uptake of a cell permeable G7‐18NATE construct into cells and binding with the Grb7‐SH2 domain

D. Krag, Matthew C.J. Wilce, M. Gunzburg, 2011, Biopolymers.

Noncovalent structure of SENP1 in complex with SUMO2.

Nigus D. Ambaye, 2019, Acta crystallographica. Section F, Structural biology communications.

Streptonigrin Inhibits SENP1 and Reduces the Protein Level of Hypoxia-Inducible Factor 1α (HIF1α) in Cells.

Nigus D. Ambaye, Yuan Chen, Swati Khanna, 2018, Biochemistry.

Noncovalent structure of SENP1 in complex with SUMO2.

Nigus D. Ambaye, 2019, Acta crystallographica. Section F, Structural biology communications.

Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction.

R. Heath, H. Hashimoto, A. Inoue, 2016, Bioorganic & medicinal chemistry.

Observation of an E2 (Ubc9)-homodimer by crystallography

John C Williams, Weidong Hu, John C. Williams, 2016, Data in brief.

Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.

Matthew C.J. Wilce, M. Gunzburg, J. Wilce, 2015, Journal of medicinal chemistry.

Benzopyrazine derivatives: A novel class of growth factor receptor bound protein 7 antagonists.

Matthew C.J. Wilce, M. Gunzburg, J. Wilce, 2011, Bioorganic & medicinal chemistry.

Design and testing of bicyclic inhibitors of Grb7--are two cycles better than one?

M. Gunzburg, J. Wilce, P. Perlmutter, 2013, Biopolymers.

Structural basis of binding by cyclic nonphosphorylated peptide antagonists of Grb7 implicated in breast cancer progression.

D. Krag, Matthew C.J. Wilce, M. Gunzburg, 2011, Journal of molecular biology.

Preparation of crystals for characterizing the Grb7 SH2 domain before and after complex formation with a bicyclic peptide antagonist.

Matthew C.J. Wilce, M. Gunzburg, J. Wilce, 2014, Acta crystallographica. Section F, Structural biology communications.

Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7

M. Gunzburg, J. Wilce, P. Perlmutter, 2016, Scientific Reports.

Novel anti‐cancer candidates from a combinatorial peptide library

Nigus D. Ambaye, Hua Yu, 2020, Chemical biology & drug design.

21 Grb 7 – A Newly Emerging Target in Pancreatic Cancer

J. Wilce, Nigus D. Ambaye, 2017 .

Grb7 - A Newly Emerging Target in Pancreatic Cancer

J. Wilce, Nigus D. Ambaye, 2012 .

Interaction of the non‐phosphorylated peptide G7‐18NATE with Grb7‐SH2 domain requires phosphate for enhanced affinity and specificity

D. Krag, M. Gunzburg, J. Wilce, 2012, Journal of molecular recognition : JMR.

Potent antitumor effects of cell-penetrating peptides targeting STAT3 axis

Hua Yu, D. Ann, A. Herrmann, 2021, JCI insight.

RWD Domain as an E2 (Ubc9)-Interaction Module*

Weidong Hu, John C. Williams, Nigus D. Ambaye, 2015, The Journal of Biological Chemistry.

Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.

M. Gunzburg, J. Wilce, D. Traore, 2015, Journal of medicinal chemistry.

The Discovery of Phenylbenzamide Derivatives as Grb7‐Based Antitumor Agents

M. Gunzburg, J. Wilce, Menachem J Gunzburg, 2013, ChemMedChem.

Interaction of the non‐phosphorylated peptide G7‐18NATE with Grb7‐SH2 domain requires phosphate for enhanced affinity and specificity

D. Krag, M. Gunzburg, J. Wilce, 2012, Journal of molecular recognition : JMR.

Use of SPR to Study the Interaction of G7-18NATE Peptide with the Grb7-SH2 Domain

D. Krag, M. Gunzburg, J. Wilce, 2010, International Journal of Peptide Research and Therapeutics.