S. Robia

发表

Novel determinant of PKC-ε anchoring at cardiac Z-lines

S. Robia, Misuk Kang, Jeffery W. Walker, 2005 .

Dynamics-Driven Allostery Underlies Ca2+-Mediated Release of SERCA Inhibition by Phospholamban.

L. M. Espinoza-Fonseca, R. Aguayo-Ortiz, S. Robia, 2020, Biophysical journal.

Protein Docking and Steered Molecular Dynamics Reveal Alternative Regulatory Sites on the SERCA Calcium Transporter

Jeffrey J. Gray, Rebecca F. Alford, J. J. Gray, 2019, bioRxiv.

A Structural Mechanism for Calcium Transporter Headpiece Closure

N. Smolin, Nikolai Smolin, Seth L. Robia, 2014, The journal of physical chemistry. B.

2-Color Calcium Pump Reveals Closure of the Cytoplasmic Headpiece with Calcium Binding

David D. Thomas, Zhìhóng Hú, Z. Hou, 2012, PloS one.

Phospholamban Binds with Differential Affinity to Calcium Pump Conformers*

A. Zima, Z. Hou, S. Robia, 2011, The Journal of Biological Chemistry.

Localization of Functional Endothelin Receptor Signaling Complexes in Cardiac Transverse Tubules*

T. Kamp, Ravi C Balijepalli, S. Robia, 2003, Journal of Biological Chemistry.

Dwarf open reading frame (DWORF) peptide is a direct activator of the sarcoplasmic reticulum calcium pump SERCA

M. J. Lemieux, A. Zima, E. Bovo, 2020, bioRxiv.

The E3 ubiquitin ligase atrophin interacting protein 4 binds directly to the chemokine receptor CXCR4 via a novel WW domain-mediated interaction.

A. Marchese, S. Robia, Deepali Bhandari, 2009, Molecular biology of the cell.

Phosphomimetic Mutations Increase Phospholamban Oligomerization and Alter the Structure of Its Regulatory Complex*

Z. Hou, S. Robia, E. Kelly, 2008, Journal of Biological Chemistry.

Fluorescence lifetime imaging microscopy reveals sodium pump dimers in live cells

L. M. Espinoza-Fonseca, P. Kekenes-Huskey, S. Robia, 2022, The Journal of biological chemistry.

The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans

E. Procko, R. Pratley, A. Mari, 2021, Molecular metabolism.

Spatiotemporally Distinct Protein Kinase D Activation in Adult Cardiomyocytes in Response to Phenylephrine and Endothelin*

A. Newton, K. Campbell, D. Bers, 2011, The Journal of Biological Chemistry.

Abstract 19557: Novel Stress Signaling JNK Regulates Pro-arrhythmic Molecular CaMKIIδ Activity and Expression in Aged Human Atrium

D. Bers, Xun Ai, Jiajie Yan, 2014 .

Serine-910 phosphorylation of focal adhesion kinase is critical for sarcomere reorganization in cardiomyocyte hypertrophy.

B. Russell, A. Samarel, Jody L. Martin, 2011, Cardiovascular research.

Isoform Specificity of the Na/K-ATPase Association and Regulation by Phospholemman*

D. Bers, J. Lingrel, S. Despa, 2009, The Journal of Biological Chemistry.

Regulation of Focal Adhesion Kinase through a Direct Interaction with an Endogenous Inhibitor.

A. Samarel, S. Robia, Taylor J. Zak, 2017, Biochemistry.

Dysferlin Forms a Dimer Mediated by the C2 Domains and the Transmembrane Domain In Vitro and in Living Cells

Z. Hou, S. Robia, Renzhi Han, 2011, PloS one.

Restriction of HIV-1 by Rhesus TRIM5 (cid:2) Is Governed by Alpha Helices in the Linker2 Region

N. Smolin, C. Wiethoff, E. Campbell, 2014 .

The anti-apoptotic protein HAX-1 is a regulator of cardiac function

P. Schroder, J. Qian, Zhiguo Zhang, 2009, Proceedings of the National Academy of Sciences.

p62/Sequestosome-1 Associates with and Sustains the Expression of Retroviral Restriction Factor TRIM5α

J. Luban, E. Campbell, Thomas Pertel, 2010, Journal of Virology.

Cardiac Calcium ATPase Dimerization Measured by Cross-Linking and Fluorescence Energy Transfer.

S. Robia, Daniel J. Blackwell, Taylor J. Zak, 2016, Biophysical journal.

Phospholamban Oligomerization, Quaternary Structure, and Sarco(endo)plasmic Reticulum Calcium ATPase Binding Measured by Fluorescence Resonance Energy Transfer in Living Cells*

D. Bers, Z. Hou, S. Robia, 2008, Journal of Biological Chemistry.

Förster Transfer Recovery Reveals That Phospholamban Exchanges Slowly From Pentamers but Rapidly From the SERCA Regulatory Complex

K. Campbell, David D. Thomas, Z. Hou, 2007, Circulation research.

Localization and kinetics of protein kinase C-epsilon anchoring in cardiac myocytes.

S. Robia, Jeffery W. Walker, J. Walker, 2001, Biophysical journal.

Lethal Arg9Cys phospholamban mutation hinders Ca2+-ATPase regulation and phosphorylation by protein kinase A

L. Masterson, G. Veglia, Z. Hou, 2011, Proceedings of the National Academy of Sciences.

Skin cells prefer a slower calcium pump

H. Young, S. Robia, 2018, The Journal of Biological Chemistry.

The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy

E. Olson, R. Bassel-Duby, Catherine A Makarewich, 2018, eLife.

A Kink in DWORF Helical Structure Controls the Activation of the Sarco-plasmic Reticulum Ca2+-ATPase

G. Veglia, A. De Simone, S. Robia, 2021, bioRxiv.

Phosphomimetic Mutations Enhance Oligomerization of Phospholemman and Modulate Its Interaction with the Na/K-ATPase*

D. Bers, S. Robia, Julie Bossuyt, 2011, The Journal of Biological Chemistry.

Focal Adhesion Kinase–Related Nonkinase Inhibits Vascular Smooth Muscle Cell Invasion by Focal Adhesion Targeting, Tyrosine 168 Phosphorylation, and Competition for p130Cas Binding

A. Samarel, Y. Koshman, M. Chu, 2011, Arteriosclerosis, thrombosis, and vascular biology.

TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions

J. Luban, E. Campbell, Jaya Sastri, 2011, Retrovirology.

FRNK Inhibition of Focal Adhesion Kinase-Dependent Signaling and Migration in Vascular Smooth Muscle Cells

A. Samarel, Y. Koshman, M. Chu, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Dwarf open reading frame (DWORF) is a direct activator of the sarcoplasmic reticulum calcium pump SERCA

M. J. Lemieux, A. Zima, E. Bovo, 2021, eLife.

Transporter Associated with Antigen Processing The ABCs of Immunology: Structure and Function of TAP, the

Lars V. Schäfer, E. Tajkhorshid, R. Tampé, 2015 .

Focal Adhesion Kinase – Related Nonkinase Inhibits Vascular Smooth Muscle Cell Invasion by Focal Adhesion Targeting , Tyrosine 168 Phosphorylation , and Competition for p 130 Cas Binding

A. Samarel, Y. Koshman, M. Chu, 2011 .

Defects in assembly explain reduced antiviral activity of the G249D polymorphism in human TRIM5α

D. Millar, N. Smolin, E. Campbell, 2019, PloS one.

Dynamic conformational changes in the rhesus TRIM5α dimer dictate the potency of HIV-1 restriction.

D. Millar, N. Smolin, E. Campbell, 2017, Virology.

FXYD proteins and sodium pump regulatory mechanisms

S. Robia, P. Artigas, John Q. Yap, 2021, The Journal of general physiology.

Restriction of HIV-1 by Rhesus TRIM5α Is Governed by Alpha Helices in the Linker2 Region

N. Smolin, C. Wiethoff, E. Campbell, 2014, Journal of Virology.

STOICHIOMETRY OF THE SODIUM PUMP-PHOSPHOLEMMAN REGULATORY COMPLEX

L. M. Espinoza-Fonseca, P. Kekenes-Huskey, S. Robia, 2021, bioRxiv.

Primitive Phospholamban- and Sarcolipin-like Peptides Inhibit the Sarcoplasmic Reticulum Calcium Pump SERCA.

M. J. Lemieux, L. M. Espinoza-Fonseca, H. Young, 2022, Biochemistry.

Sarcolambans are phospholamban- and sarcolipin-like regulators of the sarcoplasmic reticulum calcium pump SERCA

M. J. Lemieux, L. M. Espinoza-Fonseca, H. Young, 2020, bioRxiv.

Dimerization of SERCA2a Enhances Transport Rate and Improves Energetic Efficiency in Living Cells.

A. Zima, E. Bovo, R. Nikolaienko, 2020, Biophysical journal.

Newly Discovered Micropeptide Regulators of SERCA Form Oligomers but Bind to the Pump as Monomers.

Deo R. Singh, E. Olson, S. Robia, 2019, Journal of molecular biology.

Novel approach for quantification of endoplasmic reticulum Ca2+ transport.

A. Zima, E. Bovo, Ivana Y. Kuo, 2019, American journal of physiology. Heart and circulatory physiology.

Protein docking and steered molecular dynamics suggest alternative phospholamban-binding sites on the SERCA calcium transporter

Jeffrey J. Gray, Rebecca F. Alford, J. J. Gray, 2020, The Journal of Biological Chemistry.

Oligomeric Interactions of Sarcolipin and the Ca-ATPase*

David D. Thomas, Sean D. Pietrini, S. Robia, 2011, The Journal of Biological Chemistry.

Phosphorylated phospholamban stabilizes a compact conformation of the cardiac calcium-ATPase.

David D. Thomas, B. Svensson, Zhìhóng Hú, 2013, Biophysical journal.

Dilated cardiomyopathy variant R14del increases phospholamban pentamer stability, blunting dynamic regulation of cardiac calcium handling

A. Gramolini, P. Kekenes-Huskey, S. Robia, 2023, bioRxiv.

Restrictive Cardiomyopathy Troponin I R145W Mutation Does Not Perturb Myofilament Length-dependent Activation in Human Cardiac Sarcomeres*

A. V. Dvornikov, P. D. de Tombe, N. Smolin, 2016, The Journal of Biological Chemistry.

L30A Mutation of Phospholemman Mimics Effects of Cardiac Glycosides in Isolated Cardiomyocytes.

D. Bers, A. Kukol, N. Smolin, 2016, Biochemistry.

A kink in DWORF helical structure controls the activation of the sarcoplasmic reticulum Ca2+-ATPase

G. Veglia, A. De Simone, S. Robia, 2021, Structure.

Discovery of Enzyme Modulators via High-Throughput Time-Resolved FRET in Living Cells

Tory M. Schaaf, David D. Thomas, K. Zsebo, 2014, Journal of biomolecular screening.

ATP–Binding Cassette Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-Throughput Screening

David D. Thomas, S. Robia, Simon J. Gruber, 2015, Molecular Pharmacology.

RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET

A. Zima, E. Bovo, B. Svensson, 2023, bioRxiv.

Inhibitory and stimulatory micropeptides preferentially bind to different conformations of the cardiac calcium pump

P. Kekenes-Huskey, X. Fang, Jordan R. Beach, 2021, bioRxiv.

Redistribution of SERCA calcium pump conformers during intracellular calcium signaling

A. Zima, E. Bovo, N. Smolin, 2018, The Journal of Biological Chemistry.

Acute Inotropic and Lusitropic Effects of Cardiomyopathic R9C Mutation of Phospholamban*

P. D. de Tombe, S. Robia, Neha Abrol, 2015, The Journal of Biological Chemistry.

Phospholamban C-terminal Residues Are Critical Determinants of the Structure and Function of the Calcium ATPase Regulatory Complex*

N. Smolin, H. Young, S. Robia, 2014, The Journal of Biological Chemistry.

A dilated cardiomyopathy mutation of phospholamban, R14del, increases phospholamban pentamer stability.

A. Gramolini, P. Kekenes-Huskey, S. Robia, 2023, Biophysical Journal.

Molecular heterogeneity of calcium channel beta-subunits in canine and human heart: evidence for differential subcellular localization.

C. January, J. Foell, T. Kamp, 2004, Physiological genomics.

subcellular localization canine and human heart : evidence for differential-subunits in β Molecular heterogeneity of calcium channel

C. January, J. Foell, T. Kamp, 2004 .

Phospholamban Inhibits the Cardiac Calcium Pump Through Reversing the Allosteric Enhancement of Calcium Affinity by ATP

H. Khandelia, L. M. Espinoza-Fonseca, S. Robia, 2023, bioRxiv.

Dynamics-driven allostery underlies pre-activation of the regulatory Ca2+-ATPase/phospholamban complex

L. M. Espinoza-Fonseca, S. Robia, Olga N. Raguimova, 2020, bioRxiv.

Presenilin 1 is a direct regulator of the cardiac sarco/endoplasmic reticulum calcium pump.

A. Zima, E. Bovo, R. Nikolaienko, 2021, Cell calcium.

Intrinsically disordered HAX-1 regulates Ca2+ cycling by interacting with lipid membranes and the phospholamban cytoplasmic region.

Jiali Gao, G. Veglia, S. Robia, 2020, Biochimica et biophysica acta. Biomembranes.

Rheostatic Regulation of the SERCA/Phospholamban Membrane Protein Complex Using Non-Coding RNA and Single-Stranded DNA oligonucleotides

M. Bowser, G. Veglia, S. Robia, 2015, Scientific Reports.

Phospholamban pentamer quaternary conformation determined by in-gel fluorescence anisotropy.

David D. Thomas, S. Robia, Nicole C. Flohr, 2005, Biochemistry.

Relative affinity of calcium pump isoforms for phospholamban quantified by fluorescence resonance energy transfer.

Z. Hou, S. Robia, 2010, Journal of molecular biology.

Activation mechanism of the cardiac calcium pump by a small-molecule allosteric modulator

S. Robia, Carlos Cruz-Cortés, L. M. Espinoza-Fonseca, 2023, bioRxiv.

Protein carbonylation causes sarcoplasmic reticulum Ca2+ overload by increasing intracellular Na+ level in ventricular myocytes

A. Zima, E. Bovo, S. Robia, 2024, Research square.

The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy

E. Olson, R. Bassel-Duby, S. Bezprozvannaya, 2018, eLife.

Pathological mutations in the phospholamban cytoplasmic region affect its topology and dynamics modulating the extent of SERCA inhibition.

S. Robia, U. V. Reddy, Gianluigi N Veglia, 2024, Biochimica et biophysica acta. Biomembranes.

Phosphorylation of phospholamban promotes SERCA2a activation by dwarf open reading frame (DWORF).

A. Zima, E. Bovo, S. Robia, 2024, Cell calcium.

Phospholamban inhibits the cardiac calcium pump by interrupting an allosteric activation pathway

H. Khandelia, S. Robia, Ellen E. Cho, 2024, The Journal of biological chemistry.