S. Zoog

发表

Signaling and protein associations of a cell permeable CD40 complex in B cells.

M. Kehry, S. Jakes, S. Zoog, 2004, Molecular immunology.

Measurement of conatumumab‐induced apoptotic activity in tumors by fine needle aspirate sampling

Connie Y. C. Ma, R. Herbst, Cheng-Pang Hsu, 2010, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

2017 White Paper on recent issues in bioanalysis: a global perspective on immunogenicity guidelines & biomarker assay performance (Part 3 - LBA: immunogenicity, biomarkers and PK assays).

Sam H Haidar, Lauren F. Stevenson, Barry van der Strate, 2017, Bioanalysis.

Baculovirus apoptotic suppressor P49 is a substrate inhibitor of initiator caspases resistant to P35 in vivo

N. Chejanovsky, S. Zoog, P. Friesen, 2002, The EMBO journal.

Confirmatory detection of neutralizing antibodies to AAV gene therapy using a cell-based transduction inhibition assay

S. Zoog, C. Vettermann, Theresa Kasprzyk, 2022, Molecular therapy. Methods & clinical development.

Depletion of interfering IgG and IgM is critical to determine the role of IgE in pegvaliase-associated hypersensitivity.

K. Larimore, R. Zori, H. Weng, 2019, Journal of immunological methods.

Antibodies that neutralize cellular uptake of elosulfase alfa are not associated with reduced efficacy or pharmacodynamic effect in individuals with Morquio A syndrome.

B. Schweighardt, A. Bagri, C. O’Neill, 2017, Journal of immunological methods.

AMG 900, a potent inhibitor of aurora kinases causes pharmacodynamic changes in p-Histone H3 immunoreactivity in human tumor xenografts and proliferating mouse tissues

Connie Y. C. Ma, T. Bush, R. Loberg, 2014, Journal of Translational Medicine.

Leveraging image cytometry for the development of clinically feasible biomarkers: evaluation of activated caspase-3 in fine needle aspirate biopsies.

J. Ferbas, S. Zoog, Gloria Juan, 2011, Methods in cell biology.

AMG 655, a fully human agonistic antibody against TRAIL receptor-2, induces apoptosis via caspase activation in vitro and in vivo

A. Coxon, D. Branstetter, I. Foltz, 2007 .

Activity of Transgene-Produced B-Domain Deleted Factor VIII in Human Plasma Following AAV5 Gene Therapy.

K. Pasi, S. Rangarajan, G. Pierce, 2020, Blood.

Pharmacokinetic, pharmacodynamic, and immunogenic rationale for optimal dosing of pegvaliase, a PEGylated bacterial enzyme, in adult patients with phenylketonuria

B. Schweighardt, K. Larimore, B. Burton, 2021, Clinical and translational science.

Antagonists of CD117 (cKit) signaling inhibit mast cell accumulation in healing skin wounds

J. Ferbas, A. Itano, E. Trueblood, 2009, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Strategy to detect pre-existing immunity to AAV gene therapy

S. Fong, B. Carter, L. Tsuruda, 2017, Gene Therapy.

Early Phase Clinical Immunogenicity of Valoctocogene Roxaparvovec, an AAV5-Mediated Gene Therapy for Hemophilia A

B. Schweighardt, F. Mingozzi, P. Véron, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Ultra-sensitive AAV capsid detection by immunocapture-based qPCR following factor VIII gene transfer

Joshua Henshaw, S. Zoog, Fan Yang, 2021, Gene therapy.

Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay

G. Dehart, S. Zoog, Andrew C. Melton, 2018, Journal of visualized experiments : JoVE.

Crystal structure of baculovirus P35: role of a novel reactive site loop in apoptotic caspase inhibition

A. Fisher, S. Zoog, C. L. Schneider, 1999, The EMBO journal.

Caspase Inhibition by Baculovirus P35 Requires Interaction between the Reactive Site Loop and the β-Sheet Core*

J. Bertin, S. Zoog, P. Friesen, 1999, The Journal of Biological Chemistry.

Molecular Characterization of CD40 Signaling Intermediates*

B. Werneburg, M. Kehry, S. Zoog, 2001, The Journal of Biological Chemistry.

Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types

A. Coxon, D. Branstetter, I. Foltz, 2010, Cancer biology & therapy.

Monitoring cell-mediated immune responses in AAV gene therapy clinical trials using a validated IFN-γ ELISpot method

S. Janetzki, S. Zoog, C. Vettermann, 2021, Molecular therapy. Methods & clinical development.

Validation of an IFN-gamma ELISpot assay to measure cellular immune responses against viral antigens in non-human primates

S. Zoog, Fan Yang, Soumi Gupta, 2021, Gene therapy.

The Impact of Pre-existing Immunity on the Non-clinical Pharmacodynamics of AAV5-Based Gene Therapy

B. Schweighardt, C. O’Neill, L. Tsuruda, 2019, Molecular therapy. Methods & clinical development.

Achieving efficacy in subjects with sustained pegvaliase-neutralizing antibody responses.

K. Larimore, S. Zoog, J. Olbertz, 2021, Molecular genetics and metabolism.

Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials

B. Schweighardt, K. Larimore, J. Atkinson, 2018, EBioMedicine.

Reveglucosidase alfa (BMN 701), an IGF2-Tagged rhAcid α-Glucosidase, Improves Respiratory Functional Parameters in a Murine Model of Pompe Disease

C. O’Neill, L. Tsuruda, M. Butt, 2017, The Journal of Pharmacology and Experimental Therapeutics.

First-in-human study of AMG 208, an oral MET inhibitor, in adult patients (pts) with advanced solid tumors.

R. Loberg, R. Kurzrock, F. Janku, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.